AU5109298A – A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
– Google Patents
AU5109298A – A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
– Google Patents
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Info
Publication number
AU5109298A
AU5109298A
AU51092/98A
AU5109298A
AU5109298A
AU 5109298 A
AU5109298 A
AU 5109298A
AU 51092/98 A
AU51092/98 A
AU 51092/98A
AU 5109298 A
AU5109298 A
AU 5109298A
AU 5109298 A
AU5109298 A
AU 5109298A
Authority
AU
Australia
Prior art keywords
mixture
pct
aliphatic alcohols
sugar cane
primary aliphatic
Prior art date
1992-09-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU51092/98A
Other versions
AU711756B2
(en
Inventor
Rosa Mas Ferreiro
Abilio Laguna Granja
Juan Magraner Hernandez
Milagros Garcia Mesa
Daisy Carbajal Quintana
Lourdes Arruzazabala Valmana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adanifer SA
Laboratorios Dalmer SA
Original Assignee
Adanifer SA
Laboratorios Dalmer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1992-09-29
Filing date
1998-01-09
Publication date
1998-03-26
1998-01-09
Application filed by Adanifer SA, Laboratorios Dalmer SA
filed
Critical
Adanifer SA
1998-03-26
Publication of AU5109298A
publication
Critical
patent/AU5109298A/en
1999-10-21
Application granted
granted
Critical
1999-10-21
Publication of AU711756B2
publication
Critical
patent/AU711756B2/en
2013-02-25
Anticipated expiration
legal-status
Critical
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
C07C29/88—Separation; Purification; Use of additives, e.g. for stabilisation by treatment giving rise to a chemical modification of at least one compound
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/60—Salicylic acid; Derivatives thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A61P3/06—Antihyperlipidemics
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P7/00—Drugs for disorders of the blood or the extracellular fluid
A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/08—Vasodilators for multiple indications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
C07C31/02—Monohydroxylic acyclic alcohols
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
C07C31/02—Monohydroxylic acyclic alcohols
C07C31/125—Monohydroxylic acyclic alcohols containing five to twenty-two carbon atoms
Abstract
PCT No. PCT/EP93/00007 Sec. 371 Date Jul. 25, 1994 Sec. 102(e) Date Jul. 25, 1994 PCT Filed Feb. 25, 1993 PCT Pub. No. WO94/07830 PCT Pub. Date Apr. 14, 1994A mixture of higher primary aliphatic alcohols of 22 to 38 carbon atoms can be obtained by saponifying and extracting steps with organic solvents from sugar cane wax. The mixture which contains tetracosanol, hexacosanol, heptacosanol, octacosanol, nonacosanol, triacontanol, dotriacontanol and tetratriacontanol can be used for the treatment of hypercholesterolemia, and atherosclerotic complications as platelet hyperaggregabiulity, ischemia and thrombosis, and prevents drug induced gastric ulcer and improves male sexual activity.
AU51092/98A
1992-09-29
1998-01-09
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Expired
AU711756B2
(en)
Applications Claiming Priority (4)
Application Number
Priority Date
Filing Date
Title
CU10792
1992-09-29
CU92107A
CU22229A1
(en)
1992-09-29
1992-09-29
Polycosanol, a mixture of superior primary aliphatic as platelet hyperclumping, ischemic accidents, thrombosis and also effective against chemically induced gastric and procedure for its preparation from sugar cane.alcohols for treating atherosclerotic complications such
AU34939/93A
AU682462B2
(en)
1992-09-29
1993-02-25
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
PCT/EP1993/000007
WO1994007830A1
(en)
1992-09-29
1993-02-25
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Related Parent Applications (1)
Application Number
Title
Priority Date
Filing Date
AU34939/93A
Division
AU682462B2
(en)
1992-09-29
1993-02-25
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Publications (2)
Publication Number
Publication Date
AU5109298A
true
AU5109298A
(en)
1998-03-26
AU711756B2
AU711756B2
(en)
1999-10-21
Family
ID=5459372
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
AU34939/93A
Expired
AU682462B2
(en)
1992-09-29
1993-02-25
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
AU51092/98A
Expired
AU711756B2
(en)
1992-09-29
1998-01-09
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Family Applications Before (1)
Application Number
Title
Priority Date
Filing Date
AU34939/93A
Expired
AU682462B2
(en)
1992-09-29
1993-02-25
A mixture of higher primary aliphatic alcohols, its obtention from sugar cane wax and its pharmaceutical uses
Country Status (19)
Country
Link
US
(2)
US5663156A
(en)
EP
(1)
EP0619802B1
(en)
JP
(1)
JP3602531B2
(en)
KR
(1)
KR100269844B1
(en)
CN
(3)
CN1736384B
(en)
AT
(1)
ATE172954T1
(en)
AU
(2)
AU682462B2
(en)
BR
(1)
BR9305652A
(en)
CA
(1)
CA2124578C
(en)
CU
(1)
CU22229A1
(en)
DE
(1)
DE69321941T2
(en)
DK
(1)
DK0619802T3
(en)
EG
(1)
EG20174A
(en)
ES
(1)
ES2125973T3
(en)
GR
(1)
GR3029280T3
(en)
HK
(2)
HK1032356A1
(en)
HU
(2)
HU225050B1
(en)
RU
(1)
RU2163229C2
(en)
WO
(1)
WO1994007830A1
(en)
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(en)
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1992-09-29
1996-01-31
Dalmer Lab Sa
Polycosanol, a mixture of superior primary aliphatic as platelet hyperclumping, ischemic accidents, thrombosis and also effective against chemically induced gastric and procedure for its preparation from sugar cane.alcohols for treating atherosclerotic complications such
CU22412A1
(en)
*
1993-11-09
1996-01-31
Dalmer Lab Sa
A natural mixture composed of superior primary aliphatic alcohol obtained from bees wax for treating gastric ulcers and duodenals which also present anti-inflammatory activity
CU22723A1
(en)
*
1997-04-02
2002-02-28
Dalmer Lab Sa
HIGH MOLECULAR PRIMARY FAT ACIDS MIXTURE OBTAINED FROM THE CANA DE AZUCAR WAX AND ITS PHARMACEUTICAL USES
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1997-08-01
1999-03-24
Sigma Tau Ind Farmaceuti
PHARMACEUTICAL COMPOSITION CONTAINING L-CARNITINE OR AN ALCANOYL L-CARNITINE AND LONG CHAIN ALIPHATIC ALCOHOLS USEFUL FOR PREVENTION
US5952393A
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1998-02-12
1999-09-14
Sorkin, Jr.; Harlan Lee
Composition for reducing serum cholesterol levels
GB9806086D0
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1998-03-20
1998-05-20
Woolcombers Group Plc
Product and method of isolating same
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1999-06-21
2003-07-22
Hauser, Inc.
High molecular weight primary aliphatic alcohols obtained from natural products and uses thereof
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1999-06-21
2001-05-01
Cholesterol Control Laboratories, Inc.
High molecular weight primary aliphatic alcohols obtained from beeswax and pharmaceutical use thereof
US6197832B1
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1999-09-14
2001-03-06
Harlan Lee Sorkin, Jr.
Composition for reducing serum cholesterol levels
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1999-12-15
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2000-04-30
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Metaproteomics, Llc
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Unigen Pharmaceuticals, Inc.
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Volker Kuellmer
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2002-05-31
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Archer-Daniels-Midland Company
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2002-05-31
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2002-06-10
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2002-09-13
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The method of preparing high class alcohol from pollen
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2003-01-28
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Method and composition for lowering cholesterol
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CU22229A1
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1996-01-31
Dalmer Lab Sa
Polycosanol, a mixture of superior primary aliphatic as platelet hyperclumping, ischemic accidents, thrombosis and also effective against chemically induced gastric and procedure for its preparation from sugar cane.alcohols for treating atherosclerotic complications such
1992
1992-09-29
CU
CU92107A
patent/CU22229A1/en
not_active
IP Right Cessation
1993
1993-01-09
EG
EG1493A
patent/EG20174A/en
active
1993-02-25
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patent/KR100269844B1/en
not_active
IP Right Cessation
1993-02-25
WO
PCT/EP1993/000007
patent/WO1994007830A1/en
active
IP Right Grant
1993-02-25
CA
CA002124578A
patent/CA2124578C/en
not_active
Expired – Lifetime
1993-02-25
AU
AU34939/93A
patent/AU682462B2/en
not_active
Expired
1993-02-25
AT
AT93903874T
patent/ATE172954T1/en
not_active
IP Right Cessation
1993-02-25
JP
JP50860894A
patent/JP3602531B2/en
not_active
Expired – Fee Related
1993-02-25
US
US08/211,501
patent/US5663156A/en
not_active
Expired – Lifetime
1993-02-25
EP
EP93903874A
patent/EP0619802B1/en
not_active
Expired – Lifetime
1993-02-25
RU
RU94028887/04A
patent/RU2163229C2/en
active
1993-02-25
DK
DK93903874T
patent/DK0619802T3/en
active
1993-02-25
HU
HU9401938A
patent/HU225050B1/en
not_active
IP Right Cessation
1993-02-25
BR
BR9305652A
patent/BR9305652A/en
not_active
Application Discontinuation
1993-02-25
HU
HU0300408A
patent/HU0300408D0/en
unknown
1993-02-25
ES
ES93903874T
patent/ES2125973T3/en
not_active
Expired – Lifetime
1993-02-25
DE
DE69321941T
patent/DE69321941T2/en
not_active
Expired – Lifetime
1993-03-19
CN
CN2004100834974A
patent/CN1736384B/en
not_active
Expired – Fee Related
1993-03-19
CN
CN93103165A
patent/CN1084844A/en
active
Pending
1996
1996-12-23
US
US08/771,970
patent/US5856316A/en
not_active
Expired – Fee Related
1998
1998-01-09
AU
AU51092/98A
patent/AU711756B2/en
not_active
Expired
1999
1999-02-03
GR
GR990400360T
patent/GR3029280T3/en
unknown
2000
2000-01-10
CN
CNB001010573A
patent/CN1201731C/en
not_active
Expired – Fee Related
2001
2001-04-27
HK
HK01103067A
patent/HK1032356A1/en
not_active
IP Right Cessation
2006
2006-07-28
HK
HK06108438.7A
patent/HK1087935A1/en
not_active
IP Right Cessation
Also Published As
Publication number
Publication date
HK1087935A1
(en)
2006-10-27
ES2125973T3
(en)
1999-03-16
CA2124578A1
(en)
1994-04-14
EP0619802A1
(en)
1994-10-19
ATE172954T1
(en)
1998-11-15
HUT67607A
(en)
1995-04-28
EP0619802B1
(en)
1998-11-04
DE69321941D1
(en)
1998-12-10
CU22229A1
(en)
1996-01-31
DE69321941T2
(en)
1999-06-10
EG20174A
(en)
1997-08-31
BR9305652A
(en)
1996-11-19
HU9401938D0
(en)
1994-09-28
US5856316A
(en)
1999-01-05
HU0300408D0
(en)
2003-04-28
CN1084844A
(en)
1994-04-06
JP3602531B2
(en)
2004-12-15
CA2124578C
(en)
2003-12-16
CN1271577A
(en)
2000-11-01
CN1201731C
(en)
2005-05-18
KR100269844B1
(en)
2000-10-16
DK0619802T3
(en)
1999-07-19
HK1032356A1
(en)
2001-07-20
HU225050B1
(en)
2006-05-29
AU3493993A
(en)
1994-04-26
CN1736384B
(en)
2010-05-26
US5663156A
(en)
1997-09-02
AU682462B2
(en)
1997-10-09
CN1736384A
(en)
2006-02-22
RU2163229C2
(en)
2001-02-20
GR3029280T3
(en)
1999-05-28
AU711756B2
(en)
1999-10-21
JPH07505414A
(en)
1995-06-15
WO1994007830A1
(en)
1994-04-14
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