AU5132590A

AU5132590A – Method for silicon reduction with dimercaptosuccinic acid (dmsa)
– Google Patents

AU5132590A – Method for silicon reduction with dimercaptosuccinic acid (dmsa)
– Google Patents
Method for silicon reduction with dimercaptosuccinic acid (dmsa)

Info

Publication number
AU5132590A

AU5132590A
AU51325/90A
AU5132590A
AU5132590A
AU 5132590 A
AU5132590 A
AU 5132590A
AU 51325/90 A
AU51325/90 A
AU 51325/90A
AU 5132590 A
AU5132590 A
AU 5132590A
AU 5132590 A
AU5132590 A
AU 5132590A
Authority
AU
Australia
Prior art keywords
dmsa
dimercaptosuccinic acid
silicon
silicon reduction
preventing
Prior art date
1989-03-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU51325/90A
Other versions

AU626390B2
(en

Inventor
Harvey Craig Gonick
Farhad Khalil-Manesh
Elmar Willibald Johannes Weiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cedars Sinai Medical Center

Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1989-03-17
Filing date
1990-03-14
Publication date
1990-11-08

1990-03-14
Application filed by Cedars Sinai Medical Center
filed
Critical
Cedars Sinai Medical Center

1990-11-08
Publication of AU5132590A
publication
Critical
patent/AU5132590A/en

1992-07-30
Application granted
granted
Critical

1992-07-30
Publication of AU626390B2
publication
Critical
patent/AU626390B2/en

2010-03-14
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom

A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids

A61K31/19—Carboxylic acids, e.g. valproic acid

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P13/00—Drugs for disorders of the urinary system

A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P15/00—Drugs for genital or sexual disorders; Contraceptives

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer’s disease or other forms of dementia

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P39/00—General protective or antinoxious agents

A61P39/02—Antidotes

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/12—Antihypertensives

Abstract

Dimercaptosuccinic Acid (DMSA) may be used to reduce the level of silicon in blood and tissue thereby reducing blood pressure, improving kidney function, preventing or retarding the progression of chronic renal failure, treating the accumulation of silicon in advanced kidney disease, and/or preventing the onset or improving the current status of dementia and Alzheimer’s Disease.

AU51325/90A
1989-03-17
1990-03-14
Method for silicon reduction with dimercaptosuccinic acid (dmsa)

Ceased

AU626390B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US325297

1989-03-17

US07/325,297

US4962127A
(en)

1989-03-17
1989-03-17
Method for silicon reduction with dimercaptosuccinic acid (DMSA)

Publications (2)

Publication Number
Publication Date

AU5132590A
true

AU5132590A
(en)

1990-11-08

AU626390B2

AU626390B2
(en)

1992-07-30

Family
ID=23267294
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU51325/90A
Ceased

AU626390B2
(en)

1989-03-17
1990-03-14
Method for silicon reduction with dimercaptosuccinic acid (dmsa)

Country Status (9)

Country
Link

US
(1)

US4962127A
(en)

EP
(1)

EP0388241B1
(en)

JP
(1)

JPH0729917B2
(en)

KR
(1)

KR920006904B1
(en)

AT
(1)

ATE117550T1
(en)

AU
(1)

AU626390B2
(en)

DE
(1)

DE69016232T2
(en)

IE
(1)

IE66237B1
(en)

PT
(1)

PT93462B
(en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US5426122A
(en)

1989-03-17
1995-06-20
Cedars-Sinai Medical Center
Methods for reducing blood pressure with dimercaptosuccinic acid (DMSA)

AU725537B2
(en)

*

1992-12-15
2000-10-12
Cedars-Sinai Medical Center
Methods for treatment with dimercaptosuccinic acid (DMSA)

US6664239B2
(en)

*

1997-05-06
2003-12-16
Vanderbilt University
Diagnosis and management of infection caused by Chlamydia

1989

1989-03-17
US
US07/325,297
patent/US4962127A/en
not_active
Expired – Fee Related

1990

1990-03-14
AU
AU51325/90A
patent/AU626390B2/en
not_active
Ceased

1990-03-16
PT
PT93462A
patent/PT93462B/en
active
IP Right Grant

1990-03-17
JP
JP2068003A
patent/JPH0729917B2/en
not_active
Expired – Lifetime

1990-03-17
KR
KR1019900003618A
patent/KR920006904B1/en
not_active
IP Right Cessation

1990-03-19
AT
AT90302905T
patent/ATE117550T1/en
not_active
IP Right Cessation

1990-03-19
EP
EP90302905A
patent/EP0388241B1/en
not_active
Expired – Lifetime

1990-03-19
DE
DE69016232T
patent/DE69016232T2/en
not_active
Expired – Fee Related

1990-03-20
IE
IE102190A
patent/IE66237B1/en
not_active
IP Right Cessation

Also Published As

Publication number
Publication date

KR900013956A
(en)

1990-10-22

ATE117550T1
(en)

1995-02-15

EP0388241A1
(en)

1990-09-19

JPH0729917B2
(en)

1995-04-05

PT93462B
(en)

1996-03-29

PT93462A
(en)

1990-11-07

KR920006904B1
(en)

1992-08-22

IE66237B1
(en)

1995-12-13

JPH037219A
(en)

1991-01-14

AU626390B2
(en)

1992-07-30

DE69016232D1
(en)

1995-03-09

US4962127A
(en)

1990-10-09

EP0388241B1
(en)

1995-01-25

IE901021L
(en)

1990-09-17

DE69016232T2
(en)

1995-05-24

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Legal Events

Date
Code
Title
Description

2000-10-19
MK14
Patent ceased section 143(a) (annual fees not paid) or expired

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