AU534945B2

AU534945B2 – Anti-hypertensive agents
– Google Patents

AU534945B2 – Anti-hypertensive agents
– Google Patents
Anti-hypertensive agents

Info

Publication number
AU534945B2

AU534945B2
AU59227/80A
AU5922780A
AU534945B2
AU 534945 B2
AU534945 B2
AU 534945B2
AU 59227/80 A
AU59227/80 A
AU 59227/80A
AU 5922780 A
AU5922780 A
AU 5922780A
AU 534945 B2
AU534945 B2
AU 534945B2
Authority
AU
Australia
Prior art keywords
hypertensive agents
hypertensive
agents
Prior art date
1980-03-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU59227/80A
Other versions

AU5922780A
(en

Inventor
Alfred Chung
James Walter Ryan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Miami

Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1980-03-03
Filing date
1980-06-11
Publication date
1984-02-23

1980-06-11
Application filed by University of Miami
filed
Critical
University of Miami

1981-09-10
Publication of AU5922780A
publication
Critical
patent/AU5922780A/en

1984-02-23
Application granted
granted
Critical

1984-02-23
Publication of AU534945B2
publication
Critical
patent/AU534945B2/en

2000-06-11
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

C07D207/50—Nitrogen atoms

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/12—Antihypertensives

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members

C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member

C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom

C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member

C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D207/24—Oxygen or sulfur atoms

C07D207/26—2-Pyrrolidones

C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms

C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07K—PEPTIDES

C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof

C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links

C07K5/06—Dipeptides

C07K5/06086—Dipeptides with the first amino acid being basic

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07K—PEPTIDES

C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof

C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links

C07K5/06—Dipeptides

C07K5/06139—Dipeptides with the first amino acid being heterocyclic

C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K38/00—Medicinal preparations containing peptides

AU59227/80A
1980-03-03
1980-06-11
Anti-hypertensive agents

Ceased

AU534945B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US121188

1980-03-03

US06/121,188

US4692459A
(en)

1979-08-14
1980-03-03
Anti-hypertensive agents

Publications (2)

Publication Number
Publication Date

AU5922780A

AU5922780A
(en)

1981-09-10

AU534945B2
true

AU534945B2
(en)

1984-02-23

Family
ID=22395126
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU59227/80A
Ceased

AU534945B2
(en)

1980-03-03
1980-06-11
Anti-hypertensive agents

Country Status (15)

Country
Link

US
(1)

US4692459A
(en)

EP
(1)

EP0035383B1
(en)

JP
(1)

JPS56164115A
(en)

AT
(1)

AT385038B
(en)

AU
(1)

AU534945B2
(en)

DD
(1)

DD158238A5
(en)

DE
(1)

DE3163812D1
(en)

DK
(1)

DK93081A
(en)

FI
(1)

FI76558C
(en)

IE
(1)

IE51259B1
(en)

IL
(1)

IL62203A
(en)

NZ
(1)

NZ194002A
(en)

PL
(1)

PL229971A1
(en)

PT
(1)

PT70158A1
(en)

ZA
(1)

ZA803486B
(en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4692458A
(en)

*

1980-03-05
1987-09-08
University Of Miami
Anti-hypertensive agents

JPS57209270A
(en)

*

1981-06-19
1982-12-22
Chugai Pharmaceut Co Ltd
Proline derivative

DK110285A
(en)

*

1984-03-12
1985-09-13
Pfizer

POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES CONTAINING STATIN OR DERIVATIVES THEREOF AND PHARMACEUTICAL PREPARATIONS

US5025001A
(en)

*

1988-06-15
1991-06-18
Brigham And Women’s Hospital
S-nitroso derivatives of ACE inhibitors and the use thereof

US5356890A
(en)

*

1988-06-15
1994-10-18
Brigham And Women’s Hospital
S-nitroso derivatives of ace inhibitors and the use thereof

US5187183A
(en)

*

1988-06-15
1993-02-16
Brigham & Women’s Hospital
S-nitroso derivatives of ACE inhibitors and the use thereof

DE4010797A1
(en)

*

1990-04-04
1991-10-10
Hoechst Ag

SUBSTITUTED AZOLES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF

DE10115938A1
(en)

*

2001-03-30
2002-10-10
Medigene Ag Ges Fuer Molekular

Process for the preparation of oxirane carboxylic acids and derivatives thereof

US11229746B2
(en)

2006-06-22
2022-01-25
Excelsior Medical Corporation
Antiseptic cap

US9259535B2
(en)

2006-06-22
2016-02-16
Excelsior Medical Corporation
Antiseptic cap equipped syringe

US9078992B2
(en)

2008-10-27
2015-07-14
Pursuit Vascular, Inc.
Medical device for applying antimicrobial to proximal end of catheter

WO2013009998A2
(en)

2011-07-12
2013-01-17
Pursuit Vascular, Inc.
Device for delivery of antimicrobial agent into trans-dermal catheter

JP6822978B2
(en)

2015-05-08
2021-01-27
アイシーユー・メディカル・インコーポレーテッド

Medical connector configured to accept the emitter of a therapeutic agent

FI3525865T3
(en)

2016-10-14
2023-01-13

Sanitizing caps for medical connectors

WO2018204206A2
(en)

2017-05-01
2018-11-08
Icu Medical, Inc.
Medical fluid connectors and methods for providing additives in medical fluid lines

JP6600386B1
(en)

*

2018-07-06
2019-10-30
Kyb株式会社

Valve device

US11400195B2
(en)

2018-11-07
2022-08-02
Icu Medical, Inc.
Peritoneal dialysis transfer set with antimicrobial properties

US11517732B2
(en)

2018-11-07
2022-12-06
Icu Medical, Inc.
Syringe with antimicrobial properties

US11541220B2
(en)

2018-11-07
2023-01-03
Icu Medical, Inc.
Needleless connector with antimicrobial properties

US11541221B2
(en)

2018-11-07
2023-01-03
Icu Medical, Inc.
Tubing set with antimicrobial properties

US11534595B2
(en)

2018-11-07
2022-12-27
Icu Medical, Inc.
Device for delivering an antimicrobial composition into an infusion device

EP3883638A1
(en)

2018-11-21
2021-09-29
ICU Medical, Inc.
Antimicrobial device comprising a cap with ring and insert

Family Cites Families (8)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3947575A
(en)

*

1969-06-30
1976-03-30
E. R. Squibb & Sons, Inc.
Peptides as argiotensin converting enzyme inhibitors

US3832337A
(en)

*

1970-07-28
1974-08-27
Squibb & Sons Inc
Peptide enzyme inhibitors

US3891616A
(en)

*

1974-04-17
1975-06-24
Squibb & Sons Inc
Hypotensive {62 -homoaminoacid nonapeptides

US4046889A
(en)

*

1976-02-13
1977-09-06
E. R. Squibb & Sons, Inc.
Azetidine-2-carboxylic acid derivatives

US4052511A
(en)

*

1976-02-13
1977-10-04
E. R. Squibb & Sons, Inc.
Carboxyacylproline derivatives

US4053651A
(en)

*

1976-05-10
1977-10-11
E. R. Squibb & Sons, Inc.
Compounds and method for alleviating angiotensin related hypertension

US4113715A
(en)

*

1977-01-17
1978-09-12
E. R. Squibb & Sons, Inc.
Amino acid derivatives

GR73585B
(en)

*

1978-09-11
1984-03-26
Univ Miami

1979

1979-09-10
PT
PT70158A
patent/PT70158A1/en
unknown

1980

1980-03-03
US
US06/121,188
patent/US4692459A/en
not_active
Expired – Lifetime

1980-06-11
NZ
NZ194002A
patent/NZ194002A/en
unknown

1980-06-11
AU
AU59227/80A
patent/AU534945B2/en
not_active
Ceased

1980-06-11
ZA
ZA00803486A
patent/ZA803486B/en
unknown

1981

1981-02-24
IL
IL62203A
patent/IL62203A/en
unknown

1981-02-27
DE
DE8181300825T
patent/DE3163812D1/en
not_active
Expired

1981-02-27
EP
EP81300825A
patent/EP0035383B1/en
not_active
Expired

1981-03-02
AT
AT0097081A
patent/AT385038B/en
not_active
IP Right Cessation

1981-03-02
DK
DK93081A
patent/DK93081A/en
not_active
Application Discontinuation

1981-03-03
IE
IE460/81A
patent/IE51259B1/en
unknown

1981-03-03
JP
JP3042981A
patent/JPS56164115A/en
active
Granted

1981-03-03
DD
DD81228014A
patent/DD158238A5/en
not_active
IP Right Cessation

1981-03-03
FI
FI810663A
patent/FI76558C/en
not_active
IP Right Cessation

1981-03-03
PL
PL22997181A
patent/PL229971A1/xx
unknown

Also Published As

Publication number
Publication date

ATA97081A
(en)

1987-07-15

FI810663L
(en)

1981-09-04

FI76558B
(en)

1988-07-29

EP0035383B1
(en)

1984-05-30

AT385038B
(en)

1988-02-10

EP0035383A1
(en)

1981-09-09

DK93081A
(en)

1981-09-04

IE51259B1
(en)

1986-11-26

ZA803486B
(en)

1981-06-24

IE810460L
(en)

1981-09-03

JPS56164115A
(en)

1981-12-17

NZ194002A
(en)

1982-12-21

AU5922780A
(en)

1981-09-10

PT70158A1
(en)

1982-03-01

DE3163812D1
(en)

1984-07-05

PL229971A1
(en)

1982-02-01

DD158238A5
(en)

1983-01-05

IL62203A
(en)

1984-07-31

JPH03386B2
(en)

1991-01-07

US4692459A
(en)

1987-09-15

FI76558C
(en)

1988-11-10

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