AU539043B2

AU539043B2 – Stable solutions of derivatives of indole acetic and indane acetic acids
– Google Patents

AU539043B2 – Stable solutions of derivatives of indole acetic and indane acetic acids
– Google Patents
Stable solutions of derivatives of indole acetic and indane acetic acids

Info

Publication number
AU539043B2

AU539043B2
AU57330/80A
AU5733080A
AU539043B2
AU 539043 B2
AU539043 B2
AU 539043B2
AU 57330/80 A
AU57330/80 A
AU 57330/80A
AU 5733080 A
AU5733080 A
AU 5733080A
AU 539043 B2
AU539043 B2
AU 539043B2
Authority
AU
Australia
Prior art keywords
acetic
derivatives
indane
stable solutions
indole
Prior art date
1979-04-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU57330/80A
Other versions

AU5733080A
(en

Inventor
Adorjan Erdos
Eugene Etschenberg
Miklos Ghyczy
Gotz Ritzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

A Natterman und Cie GmbH

Original Assignee
A Natterman und Cie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1979-04-11
Filing date
1980-04-10
Publication date
1984-09-06

1980-04-10
Application filed by A Natterman und Cie GmbH
filed
Critical
A Natterman und Cie GmbH

1980-10-16
Publication of AU5733080A
publication
Critical
patent/AU5733080A/en

1984-09-06
Application granted
granted
Critical

1984-09-06
Publication of AU539043B2
publication
Critical
patent/AU539043B2/en

2000-04-10
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/66—Phosphorus compounds

A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols

A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids

A61K31/19—Carboxylic acids, e.g. valproic acid

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole

A61K31/404—Indoles, e.g. pindolol

A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent

A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound

A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine

A61K47/544—Phospholipids

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/0012—Galenical forms characterised by the site of application

A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

AU57330/80A
1979-04-11
1980-04-10
Stable solutions of derivatives of indole acetic and indane acetic acids

Ceased

AU539043B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

DE19792914789

DE2914789A1
(en)

1979-04-11
1979-04-11

INJECTABLE MEDICINES WITH ANTI-INFLAMMATORY EFFECT

DE29147895

1979-04-11

Publications (2)

Publication Number
Publication Date

AU5733080A

AU5733080A
(en)

1980-10-16

AU539043B2
true

AU539043B2
(en)

1984-09-06

Family
ID=6068138
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU57330/80A
Ceased

AU539043B2
(en)

1979-04-11
1980-04-10
Stable solutions of derivatives of indole acetic and indane acetic acids

Country Status (14)

Country
Link

US
(1)

US4309420A
(en)

JP
(1)

JPS55147217A
(en)

AT
(1)

AT369650B
(en)

AU
(1)

AU539043B2
(en)

BE
(1)

BE882732A
(en)

CA
(1)

CA1136048A
(en)

CH
(1)

CH642547A5
(en)

DE
(1)

DE2914789A1
(en)

FR
(1)

FR2453646A1
(en)

GB
(1)

GB2047535B
(en)

IT
(1)

IT1148791B
(en)

NL
(1)

NL8002096A
(en)

SE
(1)

SE451428B
(en)

ZA
(1)

ZA802158B
(en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE3042365A1
(en)

*

1980-11-10
1982-06-03
Harsanyi, Dr., Eugen, 5014 Kerpen

LIQUID LIQUID-CONTAINING SINGLE-PHASE MULTI-MATERIAL SYSTEMS

JPS59152348A
(en)

*

1983-02-19
1984-08-31
Kaken Pharmaceut Co Ltd
Biphenylylpropionic acid ester derivative and its preparation

US5196567A
(en)

*

1983-02-19
1993-03-23
Kaken Pharmaceutical Co., Ltd.
Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same

US5059591B1
(en)

*

1983-05-26
2000-04-25
Liposome Co Inc
Drug preparations of reduced toxicity

CA1237670A
(en)

*

1983-05-26
1988-06-07
Andrew S. Janoff
Drug preparations of reduced toxicity

JPS601122A
(en)

*

1983-06-20
1985-01-07
Green Cross Corp:The
Fat emulsion of biphenylylpropionic acid derivative

PT78628B
(en)

*

1984-05-02
1986-06-18
Liposome Co Inc
Pharmaceutical composition with reduced toxicity

IL79114A
(en)

*

1985-08-07
1990-09-17
Allergan Pharma
Method and composition for making liposomes

IT1269569B
(en)

*

1994-04-22
1997-04-08
Ugo Citernesi

PROCEDURE FOR THE PREPARATION OF COMPLEX BETWEEN PHOSPHOLIPIDS AND ACTIVE PRINCIPLES USEFUL FOR THE PRODUCTION OF LIPOSOMES AND ACTIVE PRINCIPLES AND LIPOSOMES OBTAINED WITH THE PROCEDURE

US5763422A
(en)

1995-01-27
1998-06-09
Board Of Regents, The University Of Texas System
Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein

EP0805684B1
(en)

*

1995-01-27
2002-06-12
The Board Of Regents, The University Of Texas System
Methods of enhancing the therapeutic activity of nsaids and compositions of zwitterionic phospholipids useful therein

US5955451A
(en)

*

1995-05-12
1999-09-21
The University Of Texas System Board Of Regents
Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein

US20040077604A1
(en)

2001-12-19
2004-04-22
Lenard Lichtenberger
Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity

KR102180667B1
(en)

2011-09-29
2020-11-20
피엘엑스 옵코 인코포레이티드
Ph dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same

AU2021244695A1
(en)

2020-03-26
2022-11-10
Plx Opco Inc.
Pharmaceutical carriers capable of pH dependent reconstitution and methods for making and using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

CA725596A
(en)

*

1960-08-26
1966-01-11
J. Wretlind Arvid
Method of preparing intravenously injectable fat emulsions free from side reactions or complications

GB1214515A
(en)

*

1967-04-11
1970-12-02
Sumitomi Chemical Company Ltd
Indole derivatives and salts thereof

JPS5186117A
(en)

*

1975-01-27
1976-07-28
Tanabe Seiyaku Co
Johoseibiryushiseizainoseiho

GB1523965A
(en)

*

1976-03-19
1978-09-06
Ici Ltd
Pharmaceutical compositions containing steroids

US4093733A
(en)

*

1976-09-09
1978-06-06
Merck & Co., Inc.
Parenteral suspensions

GB1575343A
(en)

*

1977-05-10
1980-09-17
Ici Ltd
Method for preparing liposome compositions containing biologically active compounds

DE2856333C2
(en)

*

1978-12-27
1983-09-22
A. Nattermann & Cie GmbH, 5000 Köln

Oral medicines with anti-inflammatory effects

1979

1979-04-11
DE
DE19792914789
patent/DE2914789A1/en
active
Granted

1980

1980-04-08
GB
GB8011633A
patent/GB2047535B/en
not_active
Expired

1980-04-08
CA
CA000349306A
patent/CA1136048A/en
not_active
Expired

1980-04-09
FR
FR8007938A
patent/FR2453646A1/en
active
Granted

1980-04-10
AT
AT0194780A
patent/AT369650B/en
not_active
IP Right Cessation

1980-04-10
CH
CH274580A
patent/CH642547A5/en
not_active
IP Right Cessation

1980-04-10
BE
BE0/200183A
patent/BE882732A/en
not_active
IP Right Cessation

1980-04-10
AU
AU57330/80A
patent/AU539043B2/en
not_active
Ceased

1980-04-10
IT
IT21300/80A
patent/IT1148791B/en
active

1980-04-10
JP
JP4632280A
patent/JPS55147217A/en
active
Granted

1980-04-10
US
US06/139,117
patent/US4309420A/en
not_active
Expired – Lifetime

1980-04-10
SE
SE8002715A
patent/SE451428B/en
not_active
IP Right Cessation

1980-04-10
ZA
ZA00802158A
patent/ZA802158B/en
unknown

1980-04-10
NL
NL8002096A
patent/NL8002096A/en
not_active
Application Discontinuation

Also Published As

Publication number
Publication date

ATA194780A
(en)

1982-06-15

DE2914789C2
(en)

1991-05-29

AT369650B
(en)

1983-01-25

CA1136048A
(en)

1982-11-23

CH642547A5
(en)

1984-04-30

JPS55147217A
(en)

1980-11-17

FR2453646A1
(en)

1980-11-07

BE882732A
(en)

1980-07-31

GB2047535B
(en)

1983-10-26

IT8021300D0
(en)

1980-04-10

AU5733080A
(en)

1980-10-16

US4309420A
(en)

1982-01-05

SE8002715L
(en)

1980-10-12

DE2914789A1
(en)

1980-10-16

IT1148791B
(en)

1986-12-03

JPH0210805B2
(en)

1990-03-09

GB2047535A
(en)

1980-12-03

NL8002096A
(en)

1980-10-14

FR2453646B1
(en)

1985-01-25

ZA802158B
(en)

1981-05-27

SE451428B
(en)

1987-10-12

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