AU5476580A - Creation of Inventions and Patents with Artificial Intelligence

AU5476580A – Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
– Google Patents

AU5476580A – Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole
– Google Patents
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole

Info

Publication number
AU5476580A

AU5476580A
AU54765/80A
AU5476580A
AU5476580A
AU 5476580 A
AU5476580 A
AU 5476580A
AU 54765/80 A
AU54765/80 A
AU 54765/80A
AU 5476580 A
AU5476580 A
AU 5476580A
AU 5476580 A
AU5476580 A
AU 5476580A
Authority
AU
Australia
Prior art keywords
pyrido
hexahydro
indole
aryl
derivative
Prior art date
1979-01-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU54765/80A
Other versions

AU521986B2
(en

Inventor
William Mckowan Welch Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1979-01-23
Filing date
1980-01-21
Publication date
1980-07-31

1980-01-21
Application filed by Pfizer Inc
filed
Critical
Pfizer Inc

1980-07-31
Publication of AU5476580A
publication
Critical
patent/AU5476580A/en

1982-05-13
Application granted
granted
Critical

1982-05-13
Publication of AU521986B2
publication
Critical
patent/AU521986B2/en

2000-01-21
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings

C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D307/32—Oxygen atoms

C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A61P25/20—Hypnotics; Sedatives

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A61P25/22—Anxiolytics

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides

C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides

C07C51/42—Separation; Purification; Stabilisation; Use of additives

C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings

C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D307/20—Oxygen atoms

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 – C07D463/00

C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 – C07D463/00 in which the condensed system contains two hetero rings

C07D471/04—Ortho-condensed systems

AU54765/80A
1979-01-23
1980-01-21
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole

Ceased

AU521986B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US005698

1979-01-23

US06/005,698

US4224329A
(en)

1979-01-23
1979-01-23
2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles

Related Child Applications (1)

Application Number
Title
Priority Date
Filing Date

AU76883/81A
Addition

AU532598B2
(en)

1981-10-27
1981-10-27
5-aryl-2-hydroxytetrahydrofurans

Publications (2)

Publication Number
Publication Date

AU5476580A
true

AU5476580A
(en)

1980-07-31

AU521986B2

AU521986B2
(en)

1982-05-13

Family
ID=21717248
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU54765/80A
Ceased

AU521986B2
(en)

1979-01-23
1980-01-21
Derivative of 5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3 – b) indole

Country Status (34)

Country
Link

US
(1)

US4224329A
(en)

JP
(4)

JPS55100386A
(en)

KR
(1)

KR830001932A
(en)

AR
(1)

AR231291A1
(en)

AT
(1)

AT376674B
(en)

AU
(1)

AU521986B2
(en)

BE
(1)

BE881283A
(en)

CA
(1)

CA1144168A
(en)

CH
(2)

CH648314A5
(en)

CS
(4)

CS221809B2
(en)

DD
(2)

DD149071A5
(en)

DE
(1)

DE3002367A1
(en)

DK
(1)

DK25580A
(en)

EG
(1)

EG14767A
(en)

FI
(1)

FI800179A
(en)

FR
(3)

FR2447379A1
(en)

GB
(1)

GB2041925B
(en)

GR
(1)

GR73567B
(en)

HU
(3)

HU188201B
(en)

IE
(1)

IE49500B1
(en)

IL
(1)

IL59189A
(en)

IN
(1)

IN153300B
(en)

IT
(1)

IT1149927B
(en)

LU
(1)

LU82105A1
(en)

NL
(1)

NL8000385A
(en)

NO
(2)

NO151895C
(en)

NZ
(3)

NZ192175A
(en)

PH
(4)

PH15736A
(en)

PL
(4)

PL126032B1
(en)

PT
(1)

PT70724A
(en)

SE
(3)

SE441358B
(en)

SU
(3)

SU1168094A3
(en)

YU
(2)

YU269379A
(en)

ZA
(1)

ZA796374B
(en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4432978A
(en)

1979-07-30
1984-02-21
Pfizer Inc.
Hexahydro-trans-pyridoindole

US4337250A
(en)

1979-07-30
1982-06-29
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

US4431646A
(en)

1979-07-30
1984-02-14
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

US4431649A
(en)

1979-07-30
1984-02-14
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

US4427679A
(en)

1981-01-16
1984-01-24
Pfizer Inc.
Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

US4467090A
(en)

1982-09-30
1984-08-21
Pfizer Inc.
Compound, 8-fluoro-5-(p-fluorophenyl)-2-[4-(p-fluorophenyl)-4-hydroxybutyryl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

US4477669A
(en)

1982-09-30
1984-10-16
Pfizer Inc.
Processes and intermediates useful in the preparation of flutroline

US4451655A
(en)

1982-05-17
1984-05-29
Pfizer Inc.
Process for preparing carboline derivatives and compounds used in their preparation

US4568748A
(en)

1982-09-30
1986-02-04
Pfizer Inc.
2-Carbobenzoxy-8-fluoro-5-(p-fluorophenyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

US4698444A
(en)

1982-09-30
1987-10-06
Pfizer Inc.
1,1-bis(p-fluorophenyl)urea

JPS61248502A
(en)

1985-04-26
1986-11-05
Pioneer Electronic Corp
Bonding method for magnetic material

US4636563A
(en)

1985-09-16
1987-01-13
American Home Products Corporation
Antipsychotic γ-carbolines

US4672117A
(en)

1985-09-16
1987-06-09
American Home Products Corporation
Antipsychotic gamma-carbolines

US4798896A
(en)

1988-01-19
1989-01-17
American Home Products Corporation
Antipsychotic gamma-carboline N-oxides

US5075315A
(en)

1990-05-17
1991-12-24
Mcneilab, Inc.
Antipsychotic hexahydro-2H-indeno[1,2-c]pyridine derivatives

IL143830A0
(en)

1998-12-21
2002-04-21
Janssen Pharmaceutica Nv
BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS

RU2329044C1
(en)

2006-11-16
2008-07-20
Андрей Александрович Иващенко
Ligands of 5-ht6 receptors, pharmaceutical formulation, production method and medical product

Family Cites Families (9)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

CA551241A
(en)

1958-01-07
S. Abbott Leslie
Production of substituted piperidines

US3382250A
(en)

1966-12-07
1968-05-07
Abbott Lab
Aroylalkyl derivatives of 1, 2, 3, 4-tetrahydro-5h-pyrido[4, 3b]indoles

US3687961A
(en)

1971-05-03
1972-08-29
Abbott Lab
8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline

AR205452A1
(en)

1973-12-06
1976-05-07
Endo Lab

METHOD TO PREPARE NEW TRANS-2, 3, 4, 4A, 5, 9B-HEXAHYDRO-5-PHENYL-1H-PYRID (4,3-B) INDOLES

JPS50126699A
(en)

1974-03-20
1975-10-04

AR207799A1
(en)

1974-04-01
1976-10-29
Pfizer

PROCEDURE TO PREPARE AZACICLO (3,4-A) -N-PHENYLINDOLES-2-SUBSTITUTE

US4001263A
(en)

1974-04-01
1977-01-04
Pfizer Inc.
5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

SE7702301L
(en)

1976-04-08
1977-10-09
Endo Lab

TRANS-HEXAHYDRO-PYRIDO-INDOLES

SE441448B
(en)

1977-05-23
1985-10-07
Pfizer

SET TO MAKE HEXAHYDRO-GAMMA CARBOL COMPOUNDS

1979

1979-01-23
US
US06/005,698
patent/US4224329A/en
not_active
Expired – Lifetime

1979-10-17
IN
IN726/DEL/79A
patent/IN153300B/en
unknown

1979-10-22
PH
PH23203A
patent/PH15736A/en
unknown

1979-11-05
YU
YU02693/79A
patent/YU269379A/en
unknown

1979-11-19
EG
EG668/79D
patent/EG14767A/en
active

1979-11-20
NZ
NZ192175A
patent/NZ192175A/en
unknown

1979-11-20
NZ
NZ197582A
patent/NZ197582A/en
unknown

1979-11-20
NZ
NZ197581A
patent/NZ197581A/en
unknown

1979-11-20
AR
AR278965A
patent/AR231291A1/en
active

1979-11-23
ZA
ZA00796374A
patent/ZA796374B/en
unknown

1979-12-28
NO
NO794317A
patent/NO151895C/en
unknown

1980

1980-01-03
CS
CS815712A
patent/CS221809B2/en
unknown

1980-01-03
CS
CS8098A
patent/CS221806B2/en
unknown

1980-01-03
CS
CS815710A
patent/CS221807B2/en
unknown

1980-01-03
CS
CS815711A
patent/CS221808B2/en
unknown

1980-01-04
HU
HU822859A
patent/HU188201B/en
unknown

1980-01-04
HU
HU8023A
patent/HU184712B/en
unknown

1980-01-04
HU
HU822858A
patent/HU189174B/en
unknown

1980-01-04
SU
SU802865803A
patent/SU1168094A3/en
active

1980-01-07
PL
PL1980231005A
patent/PL126032B1/en
unknown

1980-01-07
PL
PL1980221248A
patent/PL120774B1/en
unknown

1980-01-07
PL
PL1980231006A
patent/PL126532B1/en
unknown

1980-01-07
PL
PL1980231004A
patent/PL126867B1/en
unknown

1980-01-15
SE
SE8000329A
patent/SE441358B/en
unknown

1980-01-15
GB
GB8001232A
patent/GB2041925B/en
not_active
Expired

1980-01-18
CA
CA000343988A
patent/CA1144168A/en
not_active
Expired

1980-01-21
CH
CH5785/83A
patent/CH648314A5/en
not_active
IP Right Cessation

1980-01-21
GR
GR60998A
patent/GR73567B/el
unknown

1980-01-21
CH
CH456/80A
patent/CH651040A5/en
not_active
IP Right Cessation

1980-01-21
JP
JP561180A
patent/JPS55100386A/en
active
Granted

1980-01-21
AU
AU54765/80A
patent/AU521986B2/en
not_active
Ceased

1980-01-22
IT
IT19373/80A
patent/IT1149927B/en
active

1980-01-22
IL
IL59189A
patent/IL59189A/en
unknown

1980-01-22
NL
NL8000385A
patent/NL8000385A/en
not_active
Application Discontinuation

1980-01-22
LU
LU82105A
patent/LU82105A1/en
unknown

1980-01-22
AT
AT0033380A
patent/AT376674B/en
not_active
IP Right Cessation

1980-01-22
BE
BE0/199065A
patent/BE881283A/en
not_active
IP Right Cessation

1980-01-22
KR
KR1019800000225A
patent/KR830001932A/en
unknown

1980-01-22
IE
IE121/80A
patent/IE49500B1/en
unknown

1980-01-22
FR
FR8001301A
patent/FR2447379A1/en
active
Granted

1980-01-22
DK
DK25580A
patent/DK25580A/en
not_active
Application Discontinuation

1980-01-22
FI
FI800179A
patent/FI800179A/en
not_active
Application Discontinuation

1980-01-22
DD
DD80218578A
patent/DD149071A5/en
unknown

1980-01-23
PT
PT70724A
patent/PT70724A/en
unknown

1980-01-23
DE
DE19803002367
patent/DE3002367A1/en
not_active
Ceased

1980-05-16
JP
JP6515580A
patent/JPS5636487A/en
active
Pending

1980-05-16
JP
JP55065153A
patent/JPS5855151B2/en
not_active
Expired

1980-05-16
JP
JP6515480A
patent/JPS5636475A/en
active
Pending

1980-05-28
FR
FR8011816A
patent/FR2453175A1/en
active
Granted

1980-05-28
FR
FR8011815A
patent/FR2453174A1/en
active
Granted

1980-06-17
PH
PH24155A
patent/PH15086A/en
unknown

1980-06-17
PH
PH24153A
patent/PH15072A/en
unknown

1980-06-17
PH
PH24154A
patent/PH17773A/en
unknown

1981

1981-01-22
DD
DD22761181A
patent/DD156369A5/en
unknown

1981-01-26
SU
SU813233005A
patent/SU1080746A3/en
active

1981-01-26
SU
SU813233012A
patent/SU1333239A3/en
active

1983

1983-12-13
YU
YU02421/83A
patent/YU242183A/en
unknown

1984

1984-07-27
NO
NO843041A
patent/NO843041L/en
unknown

1984-09-11
SE
SE8404554A
patent/SE8404554D0/en
unknown

1984-09-11
SE
SE8404555A
patent/SE8404555D0/en
not_active
Application Discontinuation

Also Published As

Publication number
Publication date

IN153300B
(en)

1984-06-30

SE8000329L
(en)

1980-07-24

BE881283A
(en)

1980-07-22

CH648314A5
(en)

1985-03-15

SE8404555L
(en)

1984-09-11

NL8000385A
(en)

1980-07-25

FR2447379A1
(en)

1980-08-22

NO151895B
(en)

1985-03-18

JPS5636486A
(en)

1981-04-09

FR2453174B1
(en)

1983-07-29

PL126532B1
(en)

1983-08-31

FI800179A
(en)

1980-07-24

FR2453174A1
(en)

1980-10-31

PL221248A1
(en)

1980-12-01

YU242183A
(en)

1984-06-30

DD156369A5
(en)

1982-08-18

PT70724A
(en)

1980-02-01

NO794317L
(en)

1980-07-24

LU82105A1
(en)

1980-08-08

SU1333239A3
(en)

1987-08-23

EG14767A
(en)

1985-12-31

PH15736A
(en)

1983-03-18

DK25580A
(en)

1980-07-24

HU184712B
(en)

1984-10-29

JPS55100386A
(en)

1980-07-31

IT1149927B
(en)

1986-12-10

ZA796374B
(en)

1980-11-26

IE49500B1
(en)

1985-10-16

JPS5740151B2
(en)

1982-08-25

NZ192175A
(en)

1984-05-31

GB2041925B
(en)

1982-10-20

YU269379A
(en)

1984-04-30

US4224329A
(en)

1980-09-23

DD149071A5
(en)

1981-06-24

ATA33380A
(en)

1984-05-15

CA1144168A
(en)

1983-04-05

SU1168094A3
(en)

1985-07-15

NO151895C
(en)

1985-06-26

SE8404554L
(en)

1984-09-11

DE3002367A1
(en)

1980-07-24

NO843041L
(en)

1980-07-24

CH651040A5
(en)

1985-08-30

AT376674B
(en)

1984-12-27

CS221809B2
(en)

1983-04-29

JPS5636487A
(en)

1981-04-09

JPS5636475A
(en)

1981-04-09

FR2447379B1
(en)

1983-08-19

IT8019373D0
(en)

1980-01-22

IE800121L
(en)

1980-07-23

AU521986B2
(en)

1982-05-13

CS221808B2
(en)

1983-04-29

SE8404554D0
(en)

1984-09-11

HU189174B
(en)

1986-06-30

PL126032B1
(en)

1983-07-30

IL59189A0
(en)

1980-05-30

SE8404555D0
(en)

1984-09-11

PH15072A
(en)

1982-06-03

SE441358B
(en)

1985-09-30

NZ197582A
(en)

1984-05-31

FR2453175B1
(en)

1983-07-29

IL59189A
(en)

1984-01-31

PL126867B1
(en)

1983-09-30

KR830001932A
(en)

1983-05-19

PL120774B1
(en)

1982-03-31

AR231291A1
(en)

1984-10-31

PH15086A
(en)

1982-07-02

FR2453175A1
(en)

1980-10-31

GB2041925A
(en)

1980-09-17

SU1080746A3
(en)

1984-03-15

HU188201B
(en)

1986-03-28

CS221806B2
(en)

1983-04-29

CS221807B2
(en)

1983-04-29

JPS5855151B2
(en)

1983-12-08

PH17773A
(en)

1984-12-11

GR73567B
(en)

1984-03-16

NZ197581A
(en)

1984-05-31

Información de contacto