AU5550490A – Process for the preparation of l-alpha-glycerylphosphorylcholine and of l-alpha-glycerylphosphorylethanolamine
– Google Patents
AU5550490A – Process for the preparation of l-alpha-glycerylphosphorylcholine and of l-alpha-glycerylphosphorylethanolamine
– Google Patents
Process for the preparation of l-alpha-glycerylphosphorylcholine and of l-alpha-glycerylphosphorylethanolamine
Info
Publication number
AU5550490A
AU5550490A
AU55504/90A
AU5550490A
AU5550490A
AU 5550490 A
AU5550490 A
AU 5550490A
AU 55504/90 A
AU55504/90 A
AU 55504/90A
AU 5550490 A
AU5550490 A
AU 5550490A
AU 5550490 A
AU5550490 A
AU 5550490A
Authority
AU
Australia
Prior art keywords
pct
alpha
glycerylphosphorylethanolamine
glycerylphosphorylcholine
date nov
Prior art date
1989-05-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU55504/90A
Inventor
Giovanni Tronconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archimica SpA
Original Assignee
Istituto Chemioterapico Italiano Fine Chemicals SpA
Istituto Chemioterapico Italiano SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1989-05-08
Filing date
1990-05-04
Publication date
1990-11-29
Family has litigation
First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=11166558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU5550490(A)
“Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
1990-05-04
Application filed by Istituto Chemioterapico Italiano Fine Chemicals SpA, Istituto Chemioterapico Italiano SpA
filed
Critical
Istituto Chemioterapico Italiano Fine Chemicals SpA
1990-11-29
Publication of AU5550490A
publication
Critical
patent/AU5550490A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
239000008777
Glycerylphosphorylcholine
Substances
0.000
title
abstract
4
238000000034
method
Methods
0.000
title
abstract
2
SUHOQUVVVLNYQR-MRVPVSSYSA-N
choline alfoscerate
Chemical compound
C[N+](C)(C)CCOP([O-])(=O)OC[C@H](O)CO
SUHOQUVVVLNYQR-MRVPVSSYSA-N
0.000
title
1
SUHOQUVVVLNYQR-MRVPVSSYSA-O
glycerylphosphorylcholine
Chemical compound
C[N+](C)(C)CCO[P@](O)(=O)OC[C@H](O)CO
SUHOQUVVVLNYQR-MRVPVSSYSA-O
0.000
abstract
3
229960004956
glycerylphosphorylcholine
Drugs
0.000
abstract
3
FRMZOWIQVCBEAC-UHFFFAOYSA-N
glycerylphosphorylethanolamine
Chemical compound
OCCN(P(O)(O)=O)CC(O)CO
FRMZOWIQVCBEAC-UHFFFAOYSA-N
0.000
abstract
3
239000011347
resin
Substances
0.000
abstract
3
229920005989
resin
Polymers
0.000
abstract
3
239000000203
mixture
Substances
0.000
abstract
2
238000005406
washing
Methods
0.000
abstract
2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
Ethanol
Chemical compound
CCO
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
0.000
abstract
1
239000002253
acid
Substances
0.000
abstract
1
125000002091
cationic group
Chemical group
0.000
abstract
1
238000000746
purification
Methods
0.000
abstract
1
239000002904
solvent
Substances
0.000
abstract
1
XLYOFNOQVPJJNP-UHFFFAOYSA-N
water
Substances
O
XLYOFNOQVPJJNP-UHFFFAOYSA-N
0.000
abstract
1
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
C07F9/02—Phosphorus compounds
C07F9/06—Phosphorus compounds without P—C bonds
C07F9/08—Esters of oxyacids of phosphorus
C07F9/09—Esters of phosphoric acids
C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Abstract
PCT No. PCT/EP90/00717 Sec. 371 Date Nov. 8, 1991 Sec. 102(e) Date Nov. 8, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13552 PCT Pub. Date Nov. 15, 1990.A process for the purification of glycerylphosphorylcholine (GPC) and glycerylphosphorylethanolamine (GPE) from crude mixtures by eluting the latter on a cationic resin in acid form equilibrated in an anhydrous solvent, washing the resin with alcohol or a hydrated mixture thereof followed by washing with water, and then eluting on a strong basic resin in OH form to separate purified GPC and GPE.
AU55504/90A
1989-05-08
1990-05-04
Process for the preparation of l-alpha-glycerylphosphorylcholine and of l-alpha-glycerylphosphorylethanolamine
Abandoned
AU5550490A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
IT8920413A
IT1229238B
(en)
1989-05-08
1989-05-08
PROCEDURE FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE AND ALPHA-GLYCERYLPHOSPHORYLETHANOLAMINE.
IT20413/89
1989-05-08
Publications (1)
Publication Number
Publication Date
AU5550490A
true
AU5550490A
(en)
1990-11-29
Family
ID=11166558
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU55504/90A
Abandoned
AU5550490A
(en)
1989-05-08
1990-05-04
Process for the preparation of l-alpha-glycerylphosphorylcholine and of l-alpha-glycerylphosphorylethanolamine
Country Status (11)
Country
Link
US
(1)
US5250719A
(en)
EP
(1)
EP0471706B1
(en)
JP
(1)
JP2883202B2
(en)
AT
(1)
ATE109785T1
(en)
AU
(1)
AU5550490A
(en)
CA
(1)
CA2055503C
(en)
DE
(1)
DE69011516T2
(en)
DK
(1)
DK0471706T3
(en)
ES
(1)
ES2057561T3
(en)
IT
(1)
IT1229238B
(en)
WO
(1)
WO1990013552A1
(en)
Families Citing this family (19)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE59208905D1
(en)
*
1991-07-04
1997-10-23
Asta Medica Ag
Process for the preparation of alkylphosphocholines and pure preparation thereof
GB9201371D0
(en)
*
1992-01-22
1992-03-11
Enzymatix Ltd
Crystallisation process
IT1254991B
(en)
*
1992-06-24
1995-10-11
Chemi Spa
PROCEDURE FOR THE PREPARATION OF GLYCEROPHOSPHOLIPIDS
US5917068A
(en)
*
1995-12-29
1999-06-29
Eastman Chemical Company
Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds
US6063946A
(en)
*
1996-01-26
2000-05-16
Eastman Chemical Company
Process for the isolation of polyunsaturated fatty acids and esters thereof from complex mixtures which contain sterols and phosphorus compounds
US6200624B1
(en)
1996-01-26
2001-03-13
Abbott Laboratories
Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids
US5883273A
(en)
*
1996-01-26
1999-03-16
Abbott Laboratories
Polyunsaturated fatty acids and fatty acid esters free of sterols and phosphorus compounds
WO2009146526A1
(en)
*
2008-06-02
2009-12-10
University Of Saskatchewan
Recovery of multiple compounds and recyclable water from thin stillage
US8658401B2
(en)
*
2011-03-24
2014-02-25
Jiannan University
Method for preparing high purity L-α glycerylphosphorylcholine
ITVI20120063A1
(en)
*
2012-03-22
2013-09-23
Fortom Chimica S R L
PROCEDURE FOR THE EXTRACTION AND REFINING OF PHOSPHATIDYLCOLIN AND OTHER PHOSPHOLIPIDES FROM VEGETABLE LECITHINS
CN102875592A
(en)
*
2012-09-29
2013-01-16
常熟富士莱医药化工有限公司
Natural L-alpha-glycero-phosphatidylcholine preparation method
CN103172659A
(en)
*
2013-03-29
2013-06-26
山东罗欣药业股份有限公司
L-alpha-glyceryl phosphoryl choline crystal form compound
WO2015108355A1
(en)
*
2014-01-15
2015-07-23
지준홍
Glyceryl phosphoryl choline crystal and preparation method therefor
KR101616945B1
(en)
2014-02-10
2016-04-29
엔자이텍 주식회사
Method for Preparing Racemic or Optically Active Glycerophosphoryl choline
US20170101425A1
(en)
2014-06-10
2017-04-13
Chemi S.P.A.
Process for the purification of l-alpha-glycerophosphorylcholine
RU2685238C1
(en)
*
2016-07-01
2019-04-17
Общество с ограниченной ответственностью “ФАРМАЦЕЛЬ”
Method of producing crystalline glycerophosphatidylcholine
RU2635665C1
(en)
*
2017-02-16
2017-11-15
Общество с ограниченной ответственностью “БИОН”
METHOD FOR OBTAINING OF COMPENDIAL GRADE L-a-GLYCEROPHOSPHORYLCHOLINE
WO2023026449A1
(en)
*
2021-08-26
2023-03-02
協和発酵バイオ株式会社
Method for producing cytidine 5′-diphosphate compound
CN114106036A
(en)
*
2021-11-08
2022-03-01
云南开放大学(云南国防工业职业技术学院)
Separation and extraction method of L-alpha-glycerophosphatidylcholine
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE1543722A1
(en)
*
1966-08-25
1969-09-11
Knoll Ag
Process for the production of pure natural choline phosphoric acid diglyceride esters
FR2587574B1
(en)
*
1985-09-18
1987-10-30
Commissariat Energie Atomique
RESISTOR FOR PROCESSING MATERIALS
IT1201477B
(en)
*
1985-10-04
1989-02-02
Istituto Chemioterapico
PROCEDURE FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE, L-ALPHA-GLYCERYLPHOSPHORYLETHANOLOMINE AND L-ALPHA-GLYCERYLPHOSPHORYLINOSITOL FROM RAW AND / OR DEOLEATE LECITHINS
1989
1989-05-08
IT
IT8920413A
patent/IT1229238B/en
active
1990
1990-05-04
DK
DK90906950.2T
patent/DK0471706T3/en
active
1990-05-04
AU
AU55504/90A
patent/AU5550490A/en
not_active
Abandoned
1990-05-04
US
US07/773,923
patent/US5250719A/en
not_active
Expired – Lifetime
1990-05-04
DE
DE69011516T
patent/DE69011516T2/en
not_active
Expired – Fee Related
1990-05-04
WO
PCT/EP1990/000717
patent/WO1990013552A1/en
active
IP Right Grant
1990-05-04
JP
JP2506592A
patent/JP2883202B2/en
not_active
Expired – Fee Related
1990-05-04
CA
CA002055503A
patent/CA2055503C/en
not_active
Expired – Fee Related
1990-05-04
EP
EP90906950A
patent/EP0471706B1/en
not_active
Expired – Lifetime
1990-05-04
ES
ES90906950T
patent/ES2057561T3/en
not_active
Expired – Lifetime
1990-05-04
AT
AT90906950T
patent/ATE109785T1/en
not_active
IP Right Cessation
Also Published As
Publication number
Publication date
CA2055503A1
(en)
1990-11-09
US5250719A
(en)
1993-10-05
IT8920413D0
(en)
1989-05-08
EP0471706B1
(en)
1994-08-10
JP2883202B2
(en)
1999-04-19
DE69011516D1
(en)
1994-09-15
ES2057561T3
(en)
1994-10-16
CA2055503C
(en)
2000-01-18
DK0471706T3
(en)
1994-11-21
JPH04505013A
(en)
1992-09-03
ATE109785T1
(en)
1994-08-15
EP0471706A1
(en)
1992-02-26
WO1990013552A1
(en)
1990-11-15
IT1229238B
(en)
1991-07-26
DE69011516T2
(en)
1994-12-08
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