AU560922B2

AU560922B2 – Four phase administration of estrogen and progesteron
– Google Patents

AU560922B2 – Four phase administration of estrogen and progesteron
– Google Patents
Four phase administration of estrogen and progesteron

Info

Publication number
AU560922B2

AU560922B2
AU86976/82A
AU8697682A
AU560922B2
AU 560922 B2
AU560922 B2
AU 560922B2
AU 86976/82 A
AU86976/82 A
AU 86976/82A
AU 8697682 A
AU8697682 A
AU 8697682A
AU 560922 B2
AU560922 B2
AU 560922B2
Authority
AU
Australia
Prior art keywords
progesteron
estrogen
phase administration
administration
phase
Prior art date
1981-08-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
AU86976/82A
Other versions

AU8697682A
(en

Inventor
Richard Arthur Edgren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Syntex USA LLC

Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1981-08-10
Filing date
1982-08-09
Publication date
1987-04-30

1982-08-09
Application filed by Syntex USA LLC
filed
Critical
Syntex USA LLC

1983-02-17
Publication of AU8697682A
publication
Critical
patent/AU8697682A/en

1987-04-30
Application granted
granted
Critical

1987-04-30
Publication of AU560922B2
publication
Critical
patent/AU560922B2/en

2002-08-09
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone

AU86976/82A
1981-08-10
1982-08-09
Four phase administration of estrogen and progesteron

Expired

AU560922B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US06/291,533

US4390531A
(en)

1981-08-10
1981-08-10
Method of contraception using peak progestogen dosage

US291533

1981-08-10

Publications (2)

Publication Number
Publication Date

AU8697682A

AU8697682A
(en)

1983-02-17

AU560922B2
true

AU560922B2
(en)

1987-04-30

Family
ID=23120688
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU86976/82A
Expired

AU560922B2
(en)

1981-08-10
1982-08-09
Four phase administration of estrogen and progesteron

Country Status (9)

Country
Link

US
(1)

US4390531A
(en)

AU
(1)

AU560922B2
(en)

CA
(1)

CA1198057A
(en)

DE
(1)

DE3229612A1
(en)

GB
(1)

GB2104779B
(en)

HK
(1)

HK26087A
(en)

MY
(1)

MY8700596A
(en)

NZ
(1)

NZ201539A
(en)

SG
(1)

SG93686G
(en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party

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Priority date
Publication date
Assignee
Title

US4962098A
(en)

*

1987-06-15
1990-10-09
Warner-Lambert Company
Graduated estrogen contraceptive

US5010070A
(en)

*

1987-06-15
1991-04-23
Warner-Lambert Company
Graduated estrogen contraceptive

US5208225A
(en)

*

1986-02-27
1993-05-04
Warner-Lambert Company
Compositions containing fixed combinations

US4958736A
(en)

*

1986-03-18
1990-09-25
Gynex, Inc.
Package for oral contraceptive tablet

US4855305A
(en)

*

1987-03-23
1989-08-08
Applied Medical Research
Compositions and methods of effecting contraception utilizing melatonin

US5108995A
(en)

*

1987-09-24
1992-04-28
Jencap Research Ltd.
Hormone preparation and method

US5276022A
(en)

*

1987-09-24
1994-01-04
Jencap Research Ltd.
Hormone preparation and method

US4945103A
(en)

*

1989-01-17
1990-07-31
Michael Cohen
Method of treating pre-menstrual syndrome

DE4308406C1
(en)

*

1993-03-12
1994-06-16
Jenapharm Gmbh
Contraceptive compsn. with reduced hormone dose and reduced side-effects – contg. synergistic mixt. of biogenic, synthetic oestrogen and gestagen

DE4339934C2
(en)

*

1993-05-07
1995-05-24
Klaus Dr Med Umbreit

Anti-ovulation agent for hormonal contraception

US6407082B1
(en)

*

1996-09-13
2002-06-18
New Life Pharmaceuticals Inc.
Prevention of ovarian cancer by administration of a vitamin D compound

ZA949929B
(en)

*

1993-12-23
1995-08-23
Akzo Nobel Nv
Sugar-coated pharmaceutical dosage unit.

DE4429374C1
(en)

1994-08-12
1996-02-01
Jenapharm Gmbh

Pharmaceutical preparations for contraception / hormone substitution with biogenic estrogen component

US5547948A
(en)

*

1995-01-17
1996-08-20
American Home Products Corporation
Controlled release of steroids from sugar coatings

US5759577A
(en)

*

1995-01-17
1998-06-02
American Home Products Corporation
Controlled release of steroids from sugar coatings

FR2737411B1
(en)

*

1995-08-01
1997-10-17
Theramex

NOVEL HORMONAL DRUGS AND THEIR USE FOR CORRECTING ESTROGENIC DEFICIENCIES

DE19540253C2
(en)

*

1995-10-28
1998-06-04
Jenapharm Gmbh

Multi-phase preparation for contraception based on natural estrogens

US5747480A
(en)

*

1996-05-08
1998-05-05
American Home Products Corporation
Oral contraceptive

US6451778B1
(en)

1996-07-26
2002-09-17
Wyeth
Oral contraceptive

US6479475B1
(en)

1996-07-26
2002-11-12
Wyeth
Oral contraceptive

US5888543A
(en)

*

1996-07-26
1999-03-30
American Home Products Corporation
Oral contraceptives

US5858405A
(en)

*

1996-07-26
1999-01-12
American Home Products Corporation
Oral contraceptive

US6034074A
(en)

1996-09-13
2000-03-07
New Life Pharmaceuticals Inc.
Prevention of ovarian cancer by administration of a Vitamin D compound

US6765002B2
(en)

2000-03-21
2004-07-20
Gustavo Rodriguez
Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium

US6028064A
(en)

1996-09-13
2000-02-22
New Life Pharmaceuticals Inc.
Prevention of ovarian cancer by administration of progestin products

US6511970B1
(en)

1996-09-13
2003-01-28
New Life Pharmaceuticals Inc.
Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium

WO2001030355A1
(en)

1999-10-25
2001-05-03
Laboratoire Theramex
Contraceptive medicine based on a progestational agent and an oestrogen and preparation method

FR2754179B1
(en)

1996-10-08
1998-12-24
Theramex

NOVEL HORMONONAL COMPOSITION AND ITS USE

US5898032A
(en)

*

1997-06-23
1999-04-27
Medical College Of Hampton Roads
Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy

ATE279198T1
(en)

*

1997-08-27
2004-10-15
Ortho Mcneil Pharm Inc

COMBINATIONS OF ENDOMETRUM-SPAREING PROGESTAGENS AND ENDOMETRUM ATROPHIZING PROGESTAGENS WITH ESTROGENS, IN ORAL CONTRACEPTION

US6251956B1
(en)

1998-08-20
2001-06-26
Ortho Pharmaceutical Corporation
Combination progestin oral contraceptive regimen

EP1148884A4
(en)

*

1998-11-12
2003-06-11
Warner Chilcott Lab Ireland Lt
Graduated progestin contraceptive

US20050038006A1
(en)

*

1998-12-23
2005-02-17
Shangold Gary A.
Triphasic oral contraceptive

US6214815B1
(en)

1998-12-23
2001-04-10
Ortho-Mcneil Pharmaceuticals, Inc.
Triphasic oral contraceptive

US6855703B1
(en)

2000-03-10
2005-02-15
Endeavor Pharmaceuticals
Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds

US6660726B2
(en)

2000-03-10
2003-12-09
Endeavor Pharmaceuticals
Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same

US7459445B2
(en)

*

2000-03-10
2008-12-02
Duramed Pharmaceuticals, Inc.
Estrogenic compounds and topical pharmaceutical formulations of the same

US7989436B2
(en)

2003-07-23
2011-08-02
Duramed Pharmaceuticals, Inc.
Estrogenic compounds and pharmaceutical formulations comprising the same

US20050113351A1
(en)

*

2000-03-21
2005-05-26
Rodriguez Gustavo C.
Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium

US20010044431A1
(en)

*

2000-03-21
2001-11-22
Rodriguez Gustavo C.
Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium

US20040176336A1
(en)

*

2000-03-21
2004-09-09
Rodriguez Gustavo C.
Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium

CN101757628A
(en)

*

2001-12-05
2010-06-30
杜拉美德药物有限公司
Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology

US6992075B2
(en)

*

2003-04-04
2006-01-31
Barr Laboratories, Inc.
C(14) estrogenic compounds

WO2004091535A2
(en)

*

2003-04-11
2004-10-28
Barr Laboratories, Inc.
Methods of administering estrogens and progestins

AU2004257772B2
(en)

*

2003-07-16
2009-12-17
Teva Women’s Health, Inc.
Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration

EP2295041A3
(en)

*

2003-09-29
2012-01-04
Novo Nordisk Femcare AG
HRT formulations

AU2004275470B2
(en)

*

2003-09-29
2010-12-02
Novo Nordisk Health Care Ag
Improved stability of progestogen formulations

JP2007507534A
(en)

*

2003-10-01
2007-03-29
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ

Sustained three-phase contraception

WO2005092441A2
(en)

*

2004-03-19
2005-10-06
Warner Chilcott Company, Inc.
Extended cycle multiphasic oral contraceptive method

DE102004019743B4
(en)

*

2004-04-20
2008-11-27
Bayer Schering Pharma Aktiengesellschaft

Multiphase preparation for contraception based on natural estrogen

US20070111975A1
(en)

*

2004-10-07
2007-05-17
Duramed Pharmaceuticals, Inc.
Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens

US20060183724A1
(en)

*

2005-02-03
2006-08-17
Diliberti Charles E
Compositions of unconjugated estrogens and methods for their use

US8153616B2
(en)

2005-10-17
2012-04-10
Bayer Pharma Aktiengesellschaft
Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same

EP1930010A1
(en)

*

2006-10-20
2008-06-11
Bayer Schering Pharma Aktiengesellschaft
Application of estradiol valerate or 17ß-estradiol in combination with dienogest for oral therapy to maintain and/or increase the female libido

Family Cites Families (18)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3568828A
(en)

*

1967-03-01
1971-03-09
Squibb & Sons Inc
Modified sequential oral contraceptive

GB1175468A
(en)

*

1967-10-19
1969-12-23
Merck Ag E
Pharmaceutical Compositions

US3639600A
(en)

*

1969-08-28
1972-02-01
Upjohn Co
Process of establishing cyclicity in a human female

US3795734A
(en)

*

1970-04-20
1974-03-05
American Home Prod
Cyclic regimen of hormone administration for contraception

US3733407A
(en)

*

1971-08-25
1973-05-15
Syntex Corp
Menopause treatment

US3836651A
(en)

*

1972-02-22
1974-09-17
Biolog Concepts Inc
Novel oral contraceptive combination

DE2218831C3
(en)

*

1972-04-14
1979-08-30
Schering Ag, 1000 Berlin Und 4619 Bergkamen

Use of hormones for contraception

DE2335265A1
(en)

*

1973-07-09
1975-01-30
Schering Ag

METHOD OF CONTRACTION BY FOLLOWING STAGE COMBINATION PREPARATIONS

IE38781B1
(en)

*

1973-02-13
1978-05-24
Ciba Geigy Ag
A medicament pack for the oral treatment with oestrogen

US4066757A
(en)

*

1973-03-26
1978-01-03
Ortho Pharmaceutical Corporation
Oral contraceptive regimen

DE2365103C3
(en)

*

1973-12-21
1980-08-28
Schering Ag, 1000 Berlin Und 4619 Bergkamen

Use of hormones for contraception

DE2431694A1
(en)

*

1974-07-02
1976-03-04
Asche Ag
Sequential, two-stage contraceptive agents – contg a gestagen in the first stage, a gestagen plus oestrogen in the second stage and opt complementary placeboss

DE2431704A1
(en)

*

1974-07-02
1976-01-22
Asche Ag
Three-stage combination oral contraceptives – contg. oestrogen with increasing doses of gestagen

US4018919A
(en)

*

1975-07-16
1977-04-19
Eli Lilly And Company
Sequential contraceptive method using two types of progestational agents

DE2645307A1
(en)

*

1976-10-05
1978-04-06
Schering Ag

NEW MEANS AND NEW METHODS FOR TREATING CLIMATE FAILURE

US4143136A
(en)

*

1976-11-20
1979-03-06
Akzona Incorporated
Method of contraception

US4292315A
(en)

*

1977-12-30
1981-09-29
Nichols Vorys
Follicular phase estrogen or progestin with physiologic estrogen/progestin luteal phase replacement drug delivery system

US4425339A
(en)

*

1981-04-09
1984-01-10
Syntex (U.S.A.) Inc.
Treatment of menopausal symptoms

1981

1981-08-10
US
US06/291,533
patent/US4390531A/en
not_active
Expired – Lifetime

1982

1982-08-09
DE
DE19823229612
patent/DE3229612A1/en
active
Granted

1982-08-09
NZ
NZ201539A
patent/NZ201539A/en
unknown

1982-08-09
AU
AU86976/82A
patent/AU560922B2/en
not_active
Expired

1982-08-09
CA
CA000409011A
patent/CA1198057A/en
not_active
Expired

1982-08-09
GB
GB08222917A
patent/GB2104779B/en
not_active
Expired

1986

1986-12-09
SG
SG936/86A
patent/SG93686G/en
unknown

1987

1987-03-26
HK
HK260/87A
patent/HK26087A/en
not_active
IP Right Cessation

1987-12-30
MY
MY596/87A
patent/MY8700596A/en
unknown

Also Published As

Publication number
Publication date

GB2104779B
(en)

1984-08-15

GB2104779A
(en)

1983-03-16

US4390531A
(en)

1983-06-28

AU8697682A
(en)

1983-02-17

CA1198057A
(en)

1985-12-17

NZ201539A
(en)

1986-04-11

HK26087A
(en)

1987-04-03

DE3229612C2
(en)

1992-07-02

MY8700596A
(en)

1987-12-31

DE3229612A1
(en)

1983-02-24

SG93686G
(en)

1987-07-03

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Legal Events

Date
Code
Title
Description

2003-03-13
MK14
Patent ceased section 143(a) (annual fees not paid) or expired

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