AU561211B2 – Tissue protein pp4
– Google Patents
AU561211B2 – Tissue protein pp4
– Google Patents
Tissue protein pp4
Info
Publication number
AU561211B2
AU561211B2
AU27203/84A
AU2720384A
AU561211B2
AU 561211 B2
AU561211 B2
AU 561211B2
AU 27203/84 A
AU27203/84 A
AU 27203/84A
AU 2720384 A
AU2720384 A
AU 2720384A
AU 561211 B2
AU561211 B2
AU 561211B2
Authority
AU
Australia
Prior art keywords
alpha
protein
tissue protein
dsd
globulins
Prior art date
1983-04-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27203/84A
Other versions
AU2720384A
(en
Inventor
Hans Bohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1983-04-26
Filing date
1984-04-24
Publication date
1987-04-30
1984-04-24
Application filed by Behringwerke AG
filed
Critical
Behringwerke AG
1984-11-01
Publication of AU2720384A
publication
Critical
patent/AU2720384A/en
1987-04-30
Application granted
granted
Critical
1987-04-30
Publication of AU561211B2
publication
Critical
patent/AU561211B2/en
1998-10-29
Assigned to DADE BEHRING MARBURG GMBH
reassignment
DADE BEHRING MARBURG GMBH
Request to Amend Deed and Register
Assignors: BEHRINGWERKE AKTIENGESELLSCHAFT
2004-04-24
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
C07K14/4721—Lipocortins
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/806—Antigenic peptides or proteins
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/834—Urine; urinary system
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/834—Urine; urinary system
Y10S530/835—Kidney
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/838—Marrow; spleen
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/842—Skin; hair; nails; sebaceous glands; cerumen
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/843—Digestive system
Y10S530/844—Stomach; intestine
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Y10S530/827—Proteins from mammals or birds
Y10S530/85—Reproductive organs or embryos
Y10S530/851—Placenta; amniotic fluid
Abstract
The protein PP4 which has (a) an electrophoretic mobility in the range between that of alpha 1 and alpha 2 globulins; (b) an isoelectric point of 4.85+/-0.15; (c) a sedimentation coefficient s20,w0 of 3.3+/-0.2S; (d) a molecular weight determined in polyacrylamide gel containing sodium dodecylsulfate (DSD) of 35,000+/-5,000; (e) an extinction coefficient E1 cm1% (280 nm) of 5.9+/-0.6; (f) a carbohydrate content of 2.4+/-0.94% (g/100 g) (mannose 0.3+/-0.2%, galactose 0.4+/-0.2%, xylose 0.1+/-0.4%, glucose 0.2+/-0.1%, glucosamine 1.0+/-0.2% and neuraminic acid 0.4+/-0.2%) and (g) a specified aminoacid composition, and a process for its preparation are described. PP4 can be used to prepare antisera which can be employed to detect and determine PP4 in body fluids in order to diagnose diseases of particular organs, as a “marker” to monitor the progress of a disease or to check therapy.
AU27203/84A
1983-04-26
1984-04-24
Tissue protein pp4
Ceased
AU561211B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE3315000
1983-04-26
DE19833315000
DE3315000A1
(en)
1983-04-26
1983-04-26
TISSUE PROTEIN PP (DOWN ARROW) 4 (DOWN ARROW), METHOD FOR ITS RECOVERY AND USE
Publications (2)
Publication Number
Publication Date
AU2720384A
AU2720384A
(en)
1984-11-01
AU561211B2
true
AU561211B2
(en)
1987-04-30
Family
ID=6197344
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU27203/84A
Ceased
AU561211B2
(en)
1983-04-26
1984-04-24
Tissue protein pp4
Country Status (7)
Country
Link
US
(1)
US4507229A
(en)
EP
(1)
EP0123307B1
(en)
JP
(1)
JPS59225196A
(en)
AT
(1)
ATE53298T1
(en)
AU
(1)
AU561211B2
(en)
CA
(1)
CA1224775A
(en)
DE
(2)
DE3315000A1
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU576712B2
(en)
*
1984-03-23
1988-09-01
Dade Behring Marburg Gmbh
Tissue protein pp21
AU576996B2
(en)
*
1984-02-09
1988-09-08
Dade Behring Marburg Gmbh
Tissue protien pp19
Families Citing this family (28)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE3338480A1
(en)
*
1983-10-22
1985-05-02
Behringwerke Ag, 3550 Marburg
NEW PROTEIN PP (DOWN ARROW) 2 (DOWN ARROW) (DOWN ARROW) 0 (DOWN ARROW), METHOD FOR ITS OBTAINMENT AND USE
FI83882C
(en)
*
1984-09-21
1991-09-10
Boehringer Ingelheim Int
Process for producing blood-liver inhibitory proteins
US5264550A
(en)
*
1985-04-15
1993-11-23
Scios Nova Inc.
Human anti-inflammatory phospholipase inhibitor protein
DE3682233D1
(en)
*
1985-06-12
1991-12-05
Lubrizol Genetics Inc
MODIFIED ZEIN.
CA1265446A
(en)
*
1985-09-30
1990-02-06
Masahiro Maki
Anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component
JPH0689014B2
(en)
*
1986-01-21
1994-11-09
興和株式会社
Thrombin-binding substance and method for producing the same
US5047503A
(en)
*
1986-07-15
1991-09-10
Kowa Company, Ltd.
Thrombin-binding substance and process for its preparation
JPH08840B2
(en)
*
1986-11-14
1996-01-10
興和株式会社
Anti-PCI monoclonal antibody, anti-PCI purification method and immunoassay using the same
DE3643182A1
(en)
*
1986-12-18
1988-06-30
Behringwerke Ag
MEDICINAL PRODUCTS CONTAINING THE TISSUE PROTEIN PP4, METHOD FOR THE PRODUCTION OF PP4 AND ITS PASTEURIZATION AND THE USE OF PP4
EP0286830A3
(en)
*
1987-03-13
1990-01-24
BEHRINGWERKE Aktiengesellschaft
Process for the extraction of protein pp4 from tissues, and the use of citric acid therefor
DE3724726A1
(en)
*
1987-07-25
1989-02-02
Behringwerke Ag
METHOD FOR PURIFYING THE PLACENTARY TISSUE PROTEIN PP4
DE3737237A1
(en)
*
1987-11-03
1989-05-18
Behringwerke Ag
ANTICOAGULATORY PROTEIN PP4-X, ITS PRODUCTION AND USE
DE3737239A1
(en)
*
1987-11-03
1989-10-12
Behringwerke Ag
GENETIC PRODUCTION OF ANTICOAGULATORY PROTEIN PP4
DK0409053T3
(en)
*
1989-07-15
1993-11-08
Boehringer Ingelheim Int
Method for purifying annexins
DE59001418D1
(en)
*
1989-07-15
1993-06-17
Boehringer Ingelheim Int
AGENT CONTAINING ANTI-COAGUALITY.
DE4003773A1
(en)
*
1990-02-08
1991-08-14
Behringwerke Ag
METHOD FOR PURIFYING LIPOCORTINES
US5322655A
(en)
*
1993-02-19
1994-06-21
Thomas Engineering, Inc.
Method for monitoring and controlling the weights of each layer of a multilayer tablet
US5968477A
(en)
*
1994-01-24
1999-10-19
Neorx Corporation
Radiolabeled annexin conjugates with hexose and a chelator
US20030220233A1
(en)
*
1994-01-24
2003-11-27
Neorx Corporation
Radiolabeled annexins
CA2190727C
(en)
*
1994-05-19
2006-07-18
Sudhakar Kasina
Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6005083A
(en)
1997-03-28
1999-12-21
Neorx Corporation
Bridged aromatic substituted amine ligands with donor atoms
DE19734648A1
(en)
1997-08-11
1999-02-18
Dade Behring Marburg Gmbh
Use of annexins as a lupus anticoagulant control or standard in coagulation tests
US7635680B2
(en)
*
2001-02-21
2009-12-22
Alavita Pharmaceuticals, Inc.
Attenuation of reperfusion injury
US7645739B2
(en)
*
2001-02-21
2010-01-12
Alavita Pharmaceuticals, Inc.
Modified annexin compositions and methods of using same
US7635676B2
(en)
*
2001-02-21
2009-12-22
Alavita Pharmaccuticals, Inc.
Modified annexin proteins and methods for their use in organ transplantation
WO2002067857A2
(en)
*
2001-02-21
2002-09-06
Surromed, Inc.
Modified annexin proteins and methods for preventing thrombosis
US20090291086A1
(en)
*
2001-02-21
2009-11-26
Alavita Pharmaceuticals, Inc.
Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia
US6982154B2
(en)
*
2002-02-21
2006-01-03
Surromed, Inc.
Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease
Family Cites Families (12)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE2221261A1
(en)
*
1972-04-29
1973-11-15
Behringwerke Ag
AP GLYCOPROTEINS AND PROCEDURES FOR THEIR ISOLATION
DE2640387C3
(en)
*
1976-09-08
1981-01-22
Behringwerke Ag, 3550 Marburg
Tissue-specific protein and method for its production
DE2720704C2
(en)
*
1977-05-07
1986-09-25
Behringwerke Ag, 3550 Marburg
New glycoprotein, process for its production and its uses
DE2726886A1
(en)
*
1977-06-15
1979-01-18
Behringwerke Ag
NEW GLYCOPROTEIN AND METHOD FOR THE PRODUCTION THEREOF
DE2745680A1
(en)
*
1977-10-11
1979-04-12
Behringwerke Ag
CONTRACEPTIVE MEANS
DE2842467A1
(en)
*
1978-09-29
1980-04-10
Behringwerke Ag
NEW UBIQUITAER GEWEBSPROTEIN PP TIEF 8
DE2854759A1
(en)
*
1978-12-19
1980-07-10
Behringwerke Ag
NEW PLACENT-SPECIFIC FABRIC PROTEIN PP DEEP 10
DE2946458A1
(en)
*
1979-11-17
1981-06-11
Behringwerke Ag, 3550 Marburg
NEW PROTEIN PP (DOWN ARROW) 11 (DOWN ARROW)
DE2952792A1
(en)
*
1979-12-31
1981-07-02
Behringwerke Ag, 3550 Marburg
NEW PROTEIN (PP (DOWN ARROW) 15 (DOWN ARROW)) WITH IMMUNE SUPPRESSIVE EFFECT
DE3013724A1
(en)
*
1980-04-10
1981-10-15
Behringwerke Ag, 3550 Marburg
NEW PROTEIN PP (DOWN ARROW) 9 (DOWN ARROW), METHOD FOR ITS ENRICHMENT AND PRODUCTION AND ITS USE
DE3109629A1
(en)
*
1981-03-13
1982-09-23
Behringwerke Ag, 3550 Marburg
“NEW PROTEIN (PP (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 6 (DOWN ARROW)), METHOD FOR ITS PREPARATION AND PRODUCTION AND ITS USE”
DE3228503A1
(en)
*
1982-07-30
1984-02-02
Behringwerke Ag, 3550 Marburg
NEW PROTEIN (PP (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 7 (DOWN ARROW)), METHOD FOR ITS ENHANCEMENT AND PRODUCTION AND USE
1983
1983-04-26
DE
DE19833315000
patent/DE3315000A1/en
active
Granted
1984
1984-04-21
EP
EP84104546A
patent/EP0123307B1/en
not_active
Expired – Lifetime
1984-04-21
AT
AT84104546T
patent/ATE53298T1/en
active
1984-04-21
DE
DE8484104546T
patent/DE3482404D1/en
not_active
Expired – Fee Related
1984-04-24
US
US06/603,346
patent/US4507229A/en
not_active
Expired – Lifetime
1984-04-24
AU
AU27203/84A
patent/AU561211B2/en
not_active
Ceased
1984-04-25
CA
CA000452691A
patent/CA1224775A/en
not_active
Expired
1984-04-25
JP
JP59082120A
patent/JPS59225196A/en
active
Granted
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU576996B2
(en)
*
1984-02-09
1988-09-08
Dade Behring Marburg Gmbh
Tissue protien pp19
AU576712B2
(en)
*
1984-03-23
1988-09-01
Dade Behring Marburg Gmbh
Tissue protein pp21
Also Published As
Publication number
Publication date
JPS59225196A
(en)
1984-12-18
DE3315000A1
(en)
1984-10-31
US4507229A
(en)
1985-03-26
EP0123307A3
(en)
1987-08-26
EP0123307A2
(en)
1984-10-31
EP0123307B1
(en)
1990-06-06
DE3482404D1
(en)
1990-07-12
DE3315000C2
(en)
1991-06-27
ATE53298T1
(en)
1990-06-15
CA1224775A
(en)
1987-07-28
AU2720384A
(en)
1984-11-01
JPH0544478B2
(en)
1993-07-06
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Legal Events
Date
Code
Title
Description
2001-11-22
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
