AU585167B2

AU585167B2 – Novel substrate peptides
– Google Patents

AU585167B2 – Novel substrate peptides
– Google Patents
Novel substrate peptides

Info

Publication number
AU585167B2

AU585167B2
AU76623/87A
AU7662387A
AU585167B2
AU 585167 B2
AU585167 B2
AU 585167B2
AU 76623/87 A
AU76623/87 A
AU 76623/87A
AU 7662387 A
AU7662387 A
AU 7662387A
AU 585167 B2
AU585167 B2
AU 585167B2
Authority
AU
Australia
Prior art keywords
ala
arg
lys
ser
novel substrate
Prior art date
1986-08-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Application number
AU76623/87A
Other versions

AU7662387A
(en

Inventor
Steven Paul Adams
Luis Glaser
Dwight Arnold Towler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Washington University in St Louis WUSTL

Original Assignee
University of Washington
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1986-08-07
Filing date
1987-08-06
Publication date
1989-06-08

1987-08-06
Application filed by University of Washington, Washington University in St Louis WUSTL
filed
Critical
University of Washington

1988-02-11
Publication of AU7662387A
publication
Critical
patent/AU7662387A/en

1989-06-08
Application granted
granted
Critical

1989-06-08
Publication of AU585167B2
publication
Critical
patent/AU585167B2/en

2007-08-06
Anticipated expiration
legal-status
Critical

Status
Ceased
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07K—PEPTIDES

C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

C07K7/04—Linear peptides containing only normal peptide links

C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Abstract

A peptide substrate for myristoylating enzymes is disclosed having an amino acid sequence selected from the group consisting of the following sequences or a physiologically acceptable amide or salt derivative thereof: @ly-R-S-T-@, @ly-R-S-T-W- @, @ly-R-S-T-W-X- @ or @ly-R-S-T-W-X-Y- @, wherein R = Ala, Asn, Gln or Ser; S = Ala, Arg, Gln, Glu, Phe or Ser; T = Ala or Lys; W = Ala or Ser; X = Ala, Tyr, or Lys; Y = Arg or Pro; and Z = Arg, Leu or Lys; with the proviso that when S-T-W-X-Y-Z is Ala-Ala-Ala-Ala-Arg-Arg R is not Asn.

AU76623/87A
1986-08-07
1987-08-06
Novel substrate peptides

Ceased

AU585167B2
(en)

Applications Claiming Priority (4)

Application Number
Priority Date
Filing Date
Title

US89423586A

1986-08-07
1986-08-07

US894235

1986-08-07

US924543

1986-10-29

US06/924,543

US4740588A
(en)

1986-08-07
1986-10-29
Novel substrate peptides

Publications (2)

Publication Number
Publication Date

AU7662387A

AU7662387A
(en)

1988-02-11

AU585167B2
true

AU585167B2
(en)

1989-06-08

Family
ID=27129082
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU76623/87A
Ceased

AU585167B2
(en)

1986-08-07
1987-08-06
Novel substrate peptides

Country Status (9)

Country
Link

US
(1)

US4740588A
(en)

EP
(1)

EP0258203B1
(en)

JP
(2)

JP2674753B2
(en)

AT
(1)

ATE124955T1
(en)

AU
(1)

AU585167B2
(en)

CA
(1)

CA1308217C
(en)

DE
(1)

DE3751398T2
(en)

ES
(1)

ES2076933T3
(en)

GR
(1)

GR3017297T3
(en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4709012A
(en)

*

1986-08-07
1987-11-24
Washington University
Novel inhibitor peptides

DE68901781T2
(en)

*

1988-02-03
1993-01-07
Univ Washington

ENZYME SUBSTRATES BASED ON NEW FATTY ACID ANALOGS.

US5082967A
(en)

*

1988-06-16
1992-01-21
Washington University
Novel fatty acid analog enzyme substrates

US5073571A
(en)

*

1988-06-16
1991-12-17
Washington University
Method of inhibiting virus

US5571689A
(en)

*

1988-06-16
1996-11-05
Washington University
Method of N-acylating peptide and proteins with diheteroatom substituted analogs of myristic acid

US5320945A
(en)

*

1989-07-14
1994-06-14
Boehringer Mannheim Gmbh
Method and reagent for the determination of antithrombin III

JPH06245775A
(en)

*

1990-02-26
1994-09-06
Washington Univ
Method for myristoylation of protein n

US5444042A
(en)

*

1990-12-28
1995-08-22
Cortex Pharmaceuticals
Method of treatment of neurodegeneration with calpain inhibitors

US5362629A
(en)

*

1991-08-05
1994-11-08
President And Fellows Of Harvard College
Detection of immunosuppressants

Citations (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU7662287A
(en)

*

1986-08-07
1988-02-11

Washington University

Novel inhibitor peptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4320118A
(en)

*

1980-12-22
1982-03-16
Syntex (U.S.A.) Inc.
Deca-, undeca-, dodeca- and tridecapeptides with thymic activity

EP0105481A1
(en)

*

1982-09-30
1984-04-18
The Wellcome Foundation Limited
Novel antigens and vaccines containing them

FR2546164B1
(en)

*

1983-05-16
1987-07-17
Centre Nat Rech Scient

NOVEL PEPTIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ELASTASE INHIBITORS

1986

1986-10-29
US
US06/924,543
patent/US4740588A/en
not_active
Expired – Lifetime

1987

1987-08-06
CA
CA000543906A
patent/CA1308217C/en
not_active
Expired – Lifetime

1987-08-06
EP
EP87870109A
patent/EP0258203B1/en
not_active
Expired – Lifetime

1987-08-06
DE
DE3751398T
patent/DE3751398T2/en
not_active
Expired – Fee Related

1987-08-06
AT
AT87870109T
patent/ATE124955T1/en
not_active
IP Right Cessation

1987-08-06
ES
ES87870109T
patent/ES2076933T3/en
not_active
Expired – Lifetime

1987-08-06
AU
AU76623/87A
patent/AU585167B2/en
not_active
Ceased

1987-08-06
JP
JP62195443A
patent/JP2674753B2/en
not_active
Expired – Lifetime

1995

1995-09-05
GR
GR950402422T
patent/GR3017297T3/en
unknown

1997

1997-01-10
JP
JP9003145A
patent/JPH09235295A/en
active
Pending

Patent Citations (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU7662287A
(en)

*

1986-08-07
1988-02-11
Washington University
Novel inhibitor peptides

Also Published As

Publication number
Publication date

EP0258203A3
(en)

1990-01-31

AU7662387A
(en)

1988-02-11

JPH09235295A
(en)

1997-09-09

DE3751398D1
(en)

1995-08-17

US4740588A
(en)

1988-04-26

CA1308217C
(en)

1992-09-29

JP2674753B2
(en)

1997-11-12

DE3751398T2
(en)

1996-02-08

GR3017297T3
(en)

1995-12-31

ES2076933T3
(en)

1995-11-16

EP0258203A2
(en)

1988-03-02

JPS6344597A
(en)

1988-02-25

EP0258203B1
(en)

1995-07-12

ATE124955T1
(en)

1995-07-15

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Legal Events

Date
Code
Title
Description

2001-03-08
MK14
Patent ceased section 143(a) (annual fees not paid) or expired

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