AU611113B2 – Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
– Google Patents
AU611113B2 – Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
– Google Patents
Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
Info
Publication number
AU611113B2
AU611113B2
AU82403/87A
AU8240387A
AU611113B2
AU 611113 B2
AU611113 B2
AU 611113B2
AU 82403/87 A
AU82403/87 A
AU 82403/87A
AU 8240387 A
AU8240387 A
AU 8240387A
AU 611113 B2
AU611113 B2
AU 611113B2
Authority
AU
Australia
Prior art keywords
compounds
preparation
drugs containing
basically substituted
substituted phenylacetonitriles
Prior art date
1986-12-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU82403/87A
Other versions
AU8240387A
(en
Inventor
Verena Baldinger
Josef Gries
Manfred Raschack
Klaus Ruebsamen
Werner Seitz
Liliane Unger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1986-12-11
Filing date
1987-12-10
Publication date
1991-06-06
1987-12-10
Application filed by BASF SE
filed
Critical
BASF SE
1988-06-16
Publication of AU8240387A
publication
Critical
patent/AU8240387A/en
1991-06-06
Application granted
granted
Critical
1991-06-06
Publication of AU611113B2
publication
Critical
patent/AU611113B2/en
2007-12-10
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C255/00—Carboxylic acid nitriles
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P11/00—Drugs for disorders of the respiratory system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
Abstract
Basic-substituted phenylacetonitriles of the formula I
in which
R<1> to R<6> and n have the meaning given in the description, are suitable for combating diseases.
AU82403/87A
1986-12-11
1987-12-10
Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
Ceased
AU611113B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE3642331
1986-12-11
DE19863642331
DE3642331A1
(en)
1986-12-11
1986-12-11
BASICLY SUBSTITUTED PHENYL ACETONITRILES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM
Publications (2)
Publication Number
Publication Date
AU8240387A
AU8240387A
(en)
1988-06-16
AU611113B2
true
AU611113B2
(en)
1991-06-06
Family
ID=6315963
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU82403/87A
Ceased
AU611113B2
(en)
1986-12-11
1987-12-10
Basically substituted phenylacetonitriles, their preparation and drugs containing these compounds
Country Status (9)
Country
Link
US
(1)
US4940780A
(en)
EP
(1)
EP0271013B1
(en)
JP
(1)
JP2569088B2
(en)
AT
(1)
ATE90339T1
(en)
AU
(1)
AU611113B2
(en)
CA
(1)
CA1337991C
(en)
DE
(1)
DE3642331A1
(en)
ES
(1)
ES2054650T3
(en)
ZA
(1)
ZA879280B
(en)
Families Citing this family (13)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FI86633C
(en)
*
1985-10-18
1992-09-25
Searle & Co
FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA BICYKLOSUBSTITUERADE FENYLACETONITRILDERIVAT.
CH679150A5
(en)
*
1986-11-07
1991-12-31
Oreal
GB8823203D0
(en)
*
1988-10-04
1988-11-09
Pfizer Ltd
Therapeutic agents
CA2032872A1
(en)
*
1989-12-21
1991-06-22
Philippe R. Bovy
W-amino-.alpha.-phenylalkanonitrile derivatives
IE64870B1
(en)
*
1989-12-21
1995-09-20
Searle & Co
Methods of using 2-isopropyl-2-phenylaminovaleronitriles immunosuppressants and vasodilators
US5162569A
(en)
*
1989-12-21
1992-11-10
G. D. Searle & Co.
Phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives
US5223536A
(en)
*
1991-07-23
1993-06-29
Fmc Corporation
1,4-diaryl-1-cyclopropyl-4-substituted butanes as insecticides and acaricides
FR2717473B1
(en)
*
1994-03-16
1996-06-28
Esteve Labor Dr
Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments.
DE19502967A1
(en)
*
1995-01-31
1996-08-01
Basf Ag
Process for the resolution of 2-aryl-2-omega-alkylaminoalkanenitriles
US5859279A
(en)
*
1996-09-10
1999-01-12
Darwin Discovery Limited
Compound and process
GB9618835D0
(en)
*
1996-09-10
1996-10-23
Chiroscience Ltd
Process
US6667412B1
(en)
1999-03-16
2003-12-23
Eisai Co., Ltd.
Nitrile compound
EP1488776A4
(en)
*
2002-03-28
2005-09-07
Shiseido Co Ltd
Phenylacetonitrile derivatives and hair tonics and external preparations for skin containing the derivatives
Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU562730B2
(en)
*
1984-09-12
1987-06-18
Boehringer Mannheim Gmbh
Phenyl acetonitrice derivatives containing a nitrooxy (ono2) substituent
AU584547B2
(en)
*
1984-10-17
1989-05-25
Hokuriku Pharmaceutical Co. Limited
Pharmaceutical “ -aminoalkyl- “ -alkylphenylacetonitriles
AU590338B2
(en)
*
1985-10-18
1989-11-02
G.D. Searle & Co.
Bicyclo-substituted phenylacetonitrile derivatives
Family Cites Families (21)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CA916157A
(en)
*
1972-12-05
Dengel Ferdinand
Basically substituted phenylacetonitriles and method for their preparation
FR1449564A
(en)
*
1962-04-02
1966-05-06
Knoll Ag
Process for the preparation of phenylacetronitriles substituted with basic groups
NL127712C
(en)
*
1964-12-21
DE1493904A1
(en)
*
1965-07-31
1969-06-19
Knoll Ag
Process for the preparation of basic substituted phenylacetonitriles
DE1643429A1
(en)
*
1967-09-20
1971-01-28
Knoll Ag
Basically substituted phenylacetonitriles and process for their preparation
GB1202750A
(en)
*
1967-12-11
1970-08-19
Knoll Ag
Substituted phenylacetonitriles
US4003914A
(en)
*
1973-12-21
1977-01-18
Hoffmann-La Roche Inc.
Sulphur containing derivatives
CH611614A5
(en)
*
1973-12-21
1979-06-15
Hoffmann La Roche
Process for the preparation of heterocyclic compounds
DE2509797C2
(en)
*
1975-03-06
1985-07-18
Dr. Karl Thomae Gmbh, 7950 Biberach
Phthalimidines, their physiologically acceptable acid addition salts, processes for their preparation and pharmaceuticals containing these compounds
AT345806B
(en)
*
1975-03-06
1978-10-10
Thomae Gmbh Dr K
PROCESS FOR THE PRODUCTION OF NEW SUBSTITUTED ARYLALKYLAMINES AND THEIR SALTS
DE2631222C3
(en)
*
1976-07-12
1979-01-04
Knoll Ag, 6700 Ludwigshafen
Process for the preparation of basic substituted phenylacetonitriles
DE3144150A1
(en)
*
1981-04-10
1982-12-09
Basf Ag, 6700 Ludwigshafen
(OMEGA) -CYAN-1, (OMEGA) -DIPHENYL-AZAALKAN DERIVATIVES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM
DE3138488A1
(en)
*
1981-09-28
1983-04-14
Knoll Ag, 6700 Ludwigshafen
USE OF BASICLY SUBSTITUTED PHENYL ACETONE RITRILES IN THE PREVENTIVE FIGHT AGAINST DISEASES AND AGENTS THEREFOR
JPS59304A
(en)
*
1982-06-23
1984-01-05
Agency Of Ind Science & Technol
Fpreparation of separation membrane
JPS59146001A
(en)
*
1983-02-09
1984-08-21
Seiko Epson Corp
Spectacle lens
DE3344755A1
(en)
*
1983-12-10
1985-06-20
Basf Ag, 6700 Ludwigshafen
1,7-DIPHENYL-3-METHYLAZA-7-CYAN-8-METHYL-NONANES FOR USE IN THE FIGHT AGAINST DISEASES
DE3409612A1
(en)
*
1984-03-16
1985-09-19
Boehringer Ingelheim KG, 6507 Ingelheim
NEW SUBSTITUTED ISOCHROMANS AND OXEPINES, THEIR ACID ADDITIONAL SALTS, THE MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
GB8426738D0
(en)
*
1984-10-23
1984-11-28
Scras
Pyridine derivatives
GB8427218D0
(en)
*
1984-10-27
1984-12-05
Scras
Pyridine derivatives
US4593042A
(en)
*
1985-10-18
1986-06-03
G. D. Searle & Co.
Bicyclo-substituted phenylacetonitrile derivatives
DE3603032A1
(en)
*
1986-01-31
1987-08-06
Basf Ag
BASICLY SUBSTITUTED PHENYL ACETONITRILES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM
1986
1986-12-11
DE
DE19863642331
patent/DE3642331A1/en
not_active
Withdrawn
1987
1987-11-30
JP
JP62300314A
patent/JP2569088B2/en
not_active
Expired – Lifetime
1987-12-04
ES
ES87117946T
patent/ES2054650T3/en
not_active
Expired – Lifetime
1987-12-04
EP
EP87117946A
patent/EP0271013B1/en
not_active
Expired – Lifetime
1987-12-04
AT
AT87117946T
patent/ATE90339T1/en
not_active
IP Right Cessation
1987-12-10
ZA
ZA879280A
patent/ZA879280B/en
unknown
1987-12-10
AU
AU82403/87A
patent/AU611113B2/en
not_active
Ceased
1987-12-10
CA
CA000554039A
patent/CA1337991C/en
not_active
Expired – Fee Related
1987-12-10
US
US07/130,954
patent/US4940780A/en
not_active
Expired – Lifetime
Patent Citations (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU562730B2
(en)
*
1984-09-12
1987-06-18
Boehringer Mannheim Gmbh
Phenyl acetonitrice derivatives containing a nitrooxy (ono2) substituent
AU584547B2
(en)
*
1984-10-17
1989-05-25
Hokuriku Pharmaceutical Co. Limited
Pharmaceutical “ -aminoalkyl- “ -alkylphenylacetonitriles
AU590338B2
(en)
*
1985-10-18
1989-11-02
G.D. Searle & Co.
Bicyclo-substituted phenylacetonitrile derivatives
Also Published As
Publication number
Publication date
EP0271013A3
(en)
1990-01-24
EP0271013B1
(en)
1993-06-09
JPS63156763A
(en)
1988-06-29
JP2569088B2
(en)
1997-01-08
DE3642331A1
(en)
1988-06-23
CA1337991C
(en)
1996-01-23
ZA879280B
(en)
1989-08-30
ATE90339T1
(en)
1993-06-15
ES2054650T3
(en)
1994-08-16
US4940780A
(en)
1990-07-10
EP0271013A2
(en)
1988-06-15
AU8240387A
(en)
1988-06-16
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Legal Events
Date
Code
Title
Description
2003-07-10
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
