AU6444786A – The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations
– Google Patents
AU6444786A – The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations
– Google Patents
The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations
Info
Publication number
AU6444786A
AU6444786A
AU64447/86A
AU6444786A
AU6444786A
AU 6444786 A
AU6444786 A
AU 6444786A
AU 64447/86 A
AU64447/86 A
AU 64447/86A
AU 6444786 A
AU6444786 A
AU 6444786A
AU 6444786 A
AU6444786 A
AU 6444786A
Authority
AU
Australia
Prior art keywords
loweralkyl
hydrogen
amino
acids
benzoylbenzeneacetic
Prior art date
1985-10-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU64447/86A
Other versions
AU596813B2
(en
Inventor
Richard George Poser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-10-28
Filing date
1986-10-27
Publication date
1987-04-30
1986-10-27
Application filed by American Home Products Corp
filed
Critical
American Home Products Corp
1987-04-30
Publication of AU6444786A
publication
Critical
patent/AU6444786A/en
1990-05-17
Application granted
granted
Critical
1990-05-17
Publication of AU596813B2
publication
Critical
patent/AU596813B2/en
1992-04-30
Assigned to A.H. ROBINS COMPANY, INCORPORATED
reassignment
A.H. ROBINS COMPANY, INCORPORATED
Alteration of Name(s) in Register under S187
Assignors: A.H. ROBINS COMPANY, INCORPORATED
1999-08-12
Assigned to AMERICAN HOME PRODUCTS CORPORATION
reassignment
AMERICAN HOME PRODUCTS CORPORATION
Request to Amend Deed and Register
Assignors: A.H. ROBINS COMPANY, INCORPORATED
2006-10-27
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A61K31/19—Carboxylic acids, e.g. valproic acid
A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/04—Centrally acting analgesics, e.g. opioids
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Pain and or inflammation is treated by transdermal administration of 2-amino-3-benzoyl-benzeneacetic acids, salts and esters having the formula
wherein R<1> is hydrogen, loweralkyl or a pharmaceutically acceptable cation; R<2> is hydrogen, halogen, loweralkyl or loweralkoxy; R<3>, R<4> and R<5> are hydrogen or loweralkyl; X is hydrogen, halogen, loweralkyl, hydroxy, loweralkoxy, nitro, trifluoromethyl or loweralkylthio; Y is hydrogen, loweralkyl, loweralkoxy, nitro or trifluoromethyl and hydrates and alcoholates thereof.
AU64447/86A
1985-10-28
1986-10-27
The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations
Ceased
AU596813B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
US06/792,269
US4683242A
(en)
1985-10-28
1985-10-28
Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters
US792269
1985-10-28
Publications (2)
Publication Number
Publication Date
AU6444786A
true
AU6444786A
(en)
1987-04-30
AU596813B2
AU596813B2
(en)
1990-05-17
Family
ID=25156312
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU64447/86A
Ceased
AU596813B2
(en)
1985-10-28
1986-10-27
The use of 2-amino-3-benzoylbenzeneacetic acids and derivatives in pharmaceutical preparations
Country Status (12)
Country
Link
US
(1)
US4683242A
(en)
EP
(1)
EP0221753B1
(en)
JP
(1)
JPH07116027B2
(en)
AT
(1)
ATE71358T1
(en)
AU
(1)
AU596813B2
(en)
DE
(1)
DE3683350D1
(en)
ES
(1)
ES2039354T3
(en)
GR
(1)
GR3004278T3
(en)
HU
(1)
HU197210B
(en)
IE
(1)
IE59229B1
(en)
PH
(1)
PH22410A
(en)
ZA
(1)
ZA867988B
(en)
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1986-08-26
1988-11-01
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2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters
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1988-01-27
1990-03-20
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Locally administrable therapeutic composition for inflammatory disease
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1990-02-20
1991-05-21
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1995-12-12
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Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
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2000-03-23
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Foamy or foamable preparations containing surfactants and electrolytes
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2003-11-11
Alcon Manufacturing, Ltd.
Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
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1997-12-19
2000-05-23
Alcon Laboratories, Inc.
Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
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1998-01-08
2006-01-19
Kellogg Scott C
Agents and methods for enhancement of transdermal transport
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1998-01-08
2012-10-16
Echo Therapeutics, Inc.
Method and apparatus for enhancement of transdermal transport
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1998-01-08
2006-06-27
Sontra Medical, Inc.
System, method, and device for non-invasive body fluid sampling and analysis
US20040171980A1
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1998-12-18
2004-09-02
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Method and apparatus for enhancement of transdermal transport
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2003-08-20
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METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
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2000-08-14
2003-08-20
Alcon Inc
METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE
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2000-08-30
2003-01-07
Unimed Pharmaceuticals, Inc.
Pharmaceutical composition and method for treating hypogonadism
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2001-03-06
2002-09-12
Astrazeneca Ab
Indolone derivatives having vascular-damaging activity
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2001-04-02
2002-10-10
Alcon, Inc.
Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
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2002-05-03
2003-11-13
Alcon, Inc.
Method of treating vascular endothelial growth factor mediated vascular disorders using amfenac or nepafenac
WO2004064828A1
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2003-01-21
2004-08-05
Senju Pharmaceutical Co., Ltd.
Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
US20030187072A1
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2003-02-14
2003-10-02
Kapin Michael A.
Method of treating angiogenesis-related disorders
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2004-10-28
2012-07-17
Echo Therapeutics, Inc.
System and method for analyte sampling and analysis with hydrogel
TWI358290B
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2004-12-02
2012-02-21
Alcon Inc
Topical nepafenac formulations
PL2450041T3
(en)
2005-10-12
2019-02-28
Unimed Pharmaceuticals, Llc
Improved testosterone gel for use in the treatment of hypogonadism
US7432069B2
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*
2005-12-05
2008-10-07
Sontra Medical Corporation
Biocompatible chemically crosslinked hydrogels for glucose sensing
TW200812575A
(en)
*
2006-04-28
2008-03-16
Alcon Inc
Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
FR2909876A1
(en)
*
2006-12-19
2008-06-20
Galderma Res & Dev S N C Snc
Use of 2-(2-amino-3-benzoyl-phenyl)-acetamide and its derivatives for the preparation of a composition for the treatment of skin diseases e.g. rosacea, psoriasis or atopic dermatitis
US20080153818A1
(en)
*
2006-12-21
2008-06-26
Bingaman David P
Methods for preventing inflammation during surgery
US20090105245A1
(en)
*
2006-12-21
2009-04-23
Bingaman David P
Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
WO2008080110A1
(en)
*
2006-12-21
2008-07-03
Alcon, Inc.
Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
NZ580179A
(en)
*
2007-03-07
2011-06-30
Echo Therapeutics Inc
Transdermal analyte monitoring systems and methods for analyte detection
NZ580997A
(en)
*
2007-04-27
2011-08-26
Echo Therapeutics Inc
Dermal abrasion device with feedback electrode to deliver data on skin thickness and removable abrasion heads
GB2484843A
(en)
*
2009-10-15
2012-04-25
Johnson Matthey Plc
Polymorphs of Bromfenac sodium
US8299295B2
(en)
2009-10-15
2012-10-30
Johnson Matthey Public Limited Company
Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0
(en)
*
2009-11-12
2009-12-30
Johnson Matthey Plc
Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
CN104151182B
(en)
*
2014-06-16
2016-03-30
广东众生药业股份有限公司
The preparation method of a kind of Bromfenac sodium times semihydrate
CN104177272B
(en)
*
2014-06-16
2016-04-06
广东众生药业股份有限公司
A kind of preparation method of Bromfenac sodium
CN106404952B
(en)
*
2016-08-31
2019-06-11
辰欣佛都药业（汶上）有限公司
A kind of measuring method of the sodium bromophenolate eye drops in relation to substance
CN115093340A
(en)
*
2022-06-27
2022-09-23
辰欣药业股份有限公司
Preparation method of bromfenac sodium sesquihydrate
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* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
CH577461A5
(en)
*
1975-08-13
1976-07-15
Robins Co Inc A H
JPS53130634A
(en)
*
1977-04-20
1978-11-14
Hisamitsu Pharmaceut Co Inc
Novel 2-(3-phenoxyphenyl) propionic acid ester derivatives
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(en)
*
1980-11-28
1984-02-10
日東電工株式会社
pharmaceutical formulations
US4503073A
(en)
*
1981-01-07
1985-03-05
A. H. Robins Company, Incorporated
2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids
IL64724A0
(en)
*
1981-02-17
1982-03-31
Robins Co Inc A H
2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
JPS5883622A
(en)
*
1981-11-10
1983-05-19
Hisamitsu Pharmaceut Co Inc
Anti-inflammatory and analgesic cream agent
WO1986002636A1
(en)
*
1984-10-30
1986-05-09
Takeda Chemical Industries, Ltd.
Benzoic acid derivatives and process for their preparation
1985
1985-10-28
US
US06/792,269
patent/US4683242A/en
not_active
Expired – Lifetime
1986
1986-10-21
ZA
ZA867988A
patent/ZA867988B/en
unknown
1986-10-24
IE
IE281186A
patent/IE59229B1/en
not_active
IP Right Cessation
1986-10-24
PH
PH34409A
patent/PH22410A/en
unknown
1986-10-27
AU
AU64447/86A
patent/AU596813B2/en
not_active
Ceased
1986-10-27
HU
HU864499A
patent/HU197210B/en
not_active
IP Right Cessation
1986-10-28
JP
JP61256712A
patent/JPH07116027B2/en
not_active
Expired – Lifetime
1986-10-28
DE
DE8686308373T
patent/DE3683350D1/en
not_active
Expired – Fee Related
1986-10-28
AT
AT86308373T
patent/ATE71358T1/en
not_active
IP Right Cessation
1986-10-28
EP
EP86308373A
patent/EP0221753B1/en
not_active
Expired – Lifetime
1986-10-28
ES
ES86308373T
patent/ES2039354T3/en
not_active
Expired – Lifetime
1992
1992-04-06
GR
GR920400633T
patent/GR3004278T3/el
unknown
Also Published As
Publication number
Publication date
IE59229B1
(en)
1994-01-26
GR3004278T3
(en)
1993-03-31
EP0221753A3
(en)
1988-04-27
PH22410A
(en)
1988-08-26
ATE71358T1
(en)
1992-01-15
US4683242A
(en)
1987-07-28
HUT42948A
(en)
1987-09-28
IE862811L
(en)
1987-04-28
ES2039354T3
(en)
1996-07-16
JPS62126124A
(en)
1987-06-08
JPH07116027B2
(en)
1995-12-13
AU596813B2
(en)
1990-05-17
EP0221753B1
(en)
1992-01-08
DE3683350D1
(en)
1992-02-20
HU197210B
(en)
1989-03-28
EP0221753A2
(en)
1987-05-13
ZA867988B
(en)
1987-06-24
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Legal Events
Date
Code
Title
Description
2000-06-01
MK14
Patent ceased section 143(a) (annual fees not paid) or expired
