AU6452886A

AU6452886A – Protection of plants against viral infection
– Google Patents

AU6452886A – Protection of plants against viral infection
– Google Patents
Protection of plants against viral infection

Info

Publication number
AU6452886A

AU6452886A
AU64528/86A
AU6452886A
AU6452886A
AU 6452886 A
AU6452886 A
AU 6452886A
AU 64528/86 A
AU64528/86 A
AU 64528/86A
AU 6452886 A
AU6452886 A
AU 6452886A
AU 6452886 A
AU6452886 A
AU 6452886A
Authority
AU
Australia
Prior art keywords
plant
plant cells
protection
virus
viral infection
Prior art date
1985-10-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU64528/86A
Other versions

AU608204B2
(en

Inventor
Roger N. Beachy
Robert T. Fraley
Stephen G. Rogers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Monsanto Co

Washington University in St Louis WUSTL

Original Assignee
University of Washington
Monsanto Co
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-10-29
Filing date
1986-10-28
Publication date
1987-04-30

1986-10-28
Application filed by University of Washington, Monsanto Co, Washington University in St Louis WUSTL
filed
Critical
University of Washington

1987-04-30
Publication of AU6452886A
publication
Critical
patent/AU6452886A/en

1991-03-28
Application granted
granted
Critical

1991-03-28
Publication of AU608204B2
publication
Critical
patent/AU608204B2/en

2006-10-28
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

C12N15/09—Recombinant DNA-technology

C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing

C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07K—PEPTIDES

C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

C12N15/09—Recombinant DNA-technology

C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts

C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)

C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology

C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield

C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance

C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance

C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

C12N15/09—Recombinant DNA-technology

C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses

C12N2750/00011—Details

C12N2750/12011—Geminiviridae

C12N2750/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense

C12N2770/00011—Details

C12N2770/14011—Bromoviridae

C12N2770/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

C—CHEMISTRY; METALLURGY

C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING

C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA

C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense

C12N2770/00011—Details

C12N2770/40011—Tymoviridae

C12N2770/40022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

A process for producing genetically transformed plants which are resistant to infection by a plant virus, comprises the steps of: (a) inserting into the genome of a plant cell a recombinant, double-stranded DNA molecule comprising (i) a promoter which functions in plant cells to cause the production of RNA sequences of said plant virus; (ii) a DNA sequence that corresponds to an RNA sequence of said plant virus. (iii) a 3′ non-translated region which functions in plant cells to cause the addition of polyadenylated nucleotides to the 3′ end of said RNA sequence; (b) obtaining transformed plant cells; and (c) regenerating from the transformed plant cells genetically transformed plants which have increased resistance to infection by said plant virus. o

AU64528/86A
1985-10-29
1986-10-28
Protection of plants against viral infection

Expired

AU608204B2
(en)

Applications Claiming Priority (6)

Application Number
Priority Date
Filing Date
Title

US79238985A

1985-10-29
1985-10-29

US792389

1985-10-29

US84491886A

1986-03-27
1986-03-27

US844918

1986-03-27

US917027

1986-10-09

US06/917,027

US6608241B1
(en)

1985-10-29
1986-10-09
Protection of plants against viral infection

Publications (2)

Publication Number
Publication Date

AU6452886A
true

AU6452886A
(en)

1987-04-30

AU608204B2

AU608204B2
(en)

1991-03-28

Family
ID=27419896
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU64528/86A
Expired

AU608204B2
(en)

1985-10-29
1986-10-28
Protection of plants against viral infection

Country Status (13)

Country
Link

US
(1)

US6608241B1
(en)

EP
(1)

EP0223452B1
(en)

JP
(4)

JPH06339379A
(en)

AT
(1)

ATE136330T1
(en)

AU
(1)

AU608204B2
(en)

BG
(1)

BG49720A3
(en)

CA
(1)

CA1341565C
(en)

DE
(1)

DE3650507T2
(en)

DK
(1)

DK515186A
(en)

ES
(1)

ES2087055T3
(en)

GR
(1)

GR3020438T3
(en)

IE
(1)

IE81098B1
(en)

IL
(1)

IL80433A
(en)

Cited By (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU603351B2
(en)

*

1986-01-23
1990-11-15
Agricultural Genetics Company Limited
Modification of plant viruses or their effects

AU606382B2
(en)

*

1987-02-09
1991-02-07
Mycogen Plant Science, Inc.
Hybrid rna virus

AU612972B2
(en)

*

1986-04-02
1991-07-25
Pioneer Hi-Bred International, Inc.
Virus resistant plants having antisense rna

Families Citing this family (58)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE3650759T2
(en)

*

1985-03-21
2002-05-08
Cornell Res Foundation Inc

Resistance gained from parasite

US5175102A
(en)

*

1986-01-23
1992-12-29
Agricultural Genetics Company, Limited
Modification of plant viruses or their effects

US5107065A
(en)

*

1986-03-28
1992-04-21
Calgene, Inc.
Anti-sense regulation of gene expression in plant cells

IL81737A
(en)

*

1986-03-28
1992-11-15
Calgene Inc
Regulation of gene expression in plant cells

US5453566A
(en)

*

1986-03-28
1995-09-26
Calgene, Inc.
Antisense regulation of gene expression in plant/cells

ATE119201T1
(en)

*

1986-04-02
1995-03-15
Pioneer Hi Bred Int

VIRUS RESISTANT PLANTS WITH A VIRAL COATING PROTEIN.

EP0279433B1
(en)

*

1987-02-20
1991-10-23
Takeda Chemical Industries, Ltd.
Plants resistant to cucumber mosaic virus infection

ES2165345T3
(en)

*

1987-07-10
2002-03-16
Syngenta Participations Ag

Induced viral resistance in plants.

WO1989005858A1
(en)

*

1987-12-21
1989-06-29
The Upjohn Company
Cucumber mosaic virus coat protein gene

US5623066A
(en)

*

1987-12-21
1997-04-22
Asgrow Seed Company
Cucumber mosaic virus coat protein gene

FR2631973B1
(en)

*

1988-05-30
1992-12-11
Agronomique Inst Nat Rech

COMPLETE NUCLEOTIDE SEQUENCE OF COMPLEMENTARY DNA OF POTYVIRUS GENOMIC RNA, GENES ENCODING POTYVIRUS CAPSIDE PROTEIN AND APPLICATIONS OF THESE GENES TO CREATE POTYVIRUS-RESISTANT TRANSGENIC PLANTS

KR900702041A
(en)

*

1988-08-19
1990-12-05
로버트 에이. 아미테이지

Plant Expression Cassette

WO1990002185A1
(en)

*

1988-08-19
1990-03-08
The Upjohn Company
Cocumber mosaic virus coat protein gene

GB8827094D0
(en)

*

1988-11-19
1988-12-21
Scottish Crop Research Inst
Dna sequence encoding coat protein gene of potato leafroll virus

WO1990010076A1
(en)

*

1989-02-24
1990-09-07
Monsanto Company
Synthetic plant genes and method for preparation

US5428144A
(en)

*

1989-04-07
1995-06-27
Pioneer Hi-Bred International, Inc.
Maize dwarf mosaic virus cDNA

ATE114720T1
(en)

*

1989-09-20
1994-12-15
Upjohn Co

SOMATIC EMBRYOGENESIS OF PUMPKINS.

US5939600A
(en)

*

1989-11-03
1999-08-17
Goldbach; Robert Willem
Nucleic acids encoding tospovirus genome and expression thereof

HUT57265A
(en)

*

1989-11-03
1991-11-28
Zaadunie Bv
Process for producing plants of diminished infection-sensitivity

JPH04144685A
(en)

*

1989-11-28
1992-05-19
Nippon Oil Co Ltd
Cdna of orsv gene

FR2658988A1
(en)

*

1990-03-02
1991-09-06
Biosem
Rhizomania-resistant beet

ATE129745T1
(en)

*

1990-03-02
1995-11-15
Biocem

REGENERATION AND GENETIC TRANSFORMATION OF SUGAR BEET.

US5514570A
(en)

*

1991-08-27
1996-05-07
Cornell Research Foundation
Squash mosaic virus genes and plants transformed therewith

HU9401401D0
(en)

*

1992-01-08
1994-08-29
Sandoz Ag
Virus resistant corn plants

US5569828A
(en)

*

1993-03-24
1996-10-29
Pioneer Hi-Bred International, Inc.
Maize chlorotic dwarf virus and resistance thereto

WO1995002056A2
(en)

*

1993-07-09
1995-01-19
Asgrow Seed Company
Lettuce infectious yellows virus genes

GB9505907D0
(en)

*

1995-03-23
1995-05-10
Sandoz Ltd
Improvements in or relating to organic compounds

BR9713329A
(en)

*

1996-11-04
2000-01-25
Univ Kentucky

Resistance mediated by the coating protein in plants

GB9703146D0
(en)

1997-02-14
1997-04-02
Innes John Centre Innov Ltd
Methods and means for gene silencing in transgenic plants

GB9827152D0
(en)

1998-07-03
1999-02-03
Devgen Nv
Characterisation of gene function using double stranded rna inhibition

JP4446085B2
(en)

2001-10-05
2010-04-07
独立行政法人産業技術総合研究所

Plant introduced with phenol oxidase gene, and method for producing phenol oxidase by said plant

US7371848B2
(en)

2004-01-20
2008-05-13
Monsanto Technology Llc
Chimeric promoters comprising a caulimovirus promoter enhancer for use in plants

EP2336333A1
(en)

2004-10-21
2011-06-22
Venganza Inc.
Methods and materials for conferring resistance to pests and pathogens of plants

US7838729B2
(en)

2007-02-26
2010-11-23
Monsanto Technology Llc
Chloroplast transit peptides for efficient targeting of DMO and uses thereof

ES2562908T3
(en)

2008-04-07
2016-03-09
Monsanto Technology Llc

Plant regulatory elements and their uses

US20120277117A1
(en)

2009-02-27
2012-11-01
Adel Zayed
Hydroponic apparatus and methods of use

US20100257634A1
(en)

*

2009-04-03
2010-10-07
Venganza Inc.
Bioassay for gene silencing constructs

US8937214B2
(en)

2009-10-23
2015-01-20
Monsanto Technology Llc
Methods and compositions for expression of transgenes in plants

CA2786697C
(en)

2010-01-14
2018-10-30
Stanislaw Flasinski
Plant regulatory elements and uses thereof

PT2611925T
(en)

2010-08-30
2018-03-02
Dow Agrosciences Llc
Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics

CN103534267B
(en)

2011-03-25
2017-07-14
孟山都技术公司
Plant control element and application thereof

EP2752492B1
(en)

2011-05-13
2018-01-31
Monsanto Technology LLC
Plant regulatory elements and uses thereof

KR20140130506A
(en)

2012-02-29
2014-11-10
다우 아그로사이언시즈 엘엘씨
Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics

US9663793B2
(en)

2012-04-20
2017-05-30
Monsanto Technology, Llc
Plant regulatory elements and uses thereof

ES2691941T3
(en)

2012-12-19
2018-11-29
Monsanto Technology Llc

Regulatory elements of plants and their uses

UA121457C2
(en)

2013-03-14
2020-06-10
Монсанто Текнолоджи Ллс
Plant regulatory elements and uses thereof

KR102270068B1
(en)

2013-03-14
2021-06-28
몬산토 테크놀로지 엘엘씨
Plant regulatory elements and uses thereof

WO2016154631A1
(en)

2015-03-26
2016-09-29
The Texas A&M University System
Conversion of lignin into bioplastics and lipid fuels

AU2017229608B2
(en)

2016-03-11
2022-12-01
Monsanto Technology Llc
Plant regulatory elements and uses thereof

UA126798C2
(en)

2016-05-24
2023-02-08
Монсанто Текнолоджі Ллс
Plant regulatory elements and uses thereof

CA3029271A1
(en)

2016-06-28
2018-01-04
Cellectis
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences

US11236355B2
(en)

*

2017-08-22
2022-02-01
The Regents Of The University Of California
ROQ1 provides resistance to both xanthomonas and pseudomonas in plants

US20200332311A1
(en)

2018-01-12
2020-10-22
The Texas A&M University System
Increasing plant bioproduct yield

WO2022204464A1
(en)

2021-03-26
2022-09-29
Flagship Pioneering Innovations Vii, Llc
Production of circular polyribonucleotides in a eukaryotic system

CN117120605A
(en)

2021-03-26
2023-11-24
旗舰创业创新七公司
Compositions and methods for producing cyclic polyribonucleotides

TW202305130A
(en)

2021-03-26
2023-02-01
美商旗艦先鋒創新有限責任(Vii)公司
Production of circular polyribonucleotides in a prokaryotic system

WO2023077118A1
(en)

2021-11-01
2023-05-04
Flagship Pioneering Innovations Vii, Llc
Polynucleotides for modifying organisms

WO2023141540A2
(en)

2022-01-20
2023-07-27
Flagship Pioneering Innovations Vii, Llc
Polynucleotides for modifying organisms

Family Cites Families (10)

* Cited by examiner, † Cited by third party

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Priority date
Publication date
Assignee
Title

US4407956A
(en)

*

1981-03-13
1983-10-04
The Regents Of The University Of California
Cloned cauliflower mosaic virus DNA as a plant vehicle

US4527287A
(en)

1983-06-24
1985-07-09
Figgie International Inc.
Baseball glove or mitt

WO1985004898A1
(en)

1984-04-26
1985-11-07
The Australian National University
An improved method of cloning double-stranded rna, and its use in the production of viral gene clones

DE3650759T2
(en)

1985-03-21
2002-05-08
Cornell Res Foundation Inc

Resistance gained from parasite

US5580716A
(en)

1985-03-21
1996-12-03
Stephen A. Johnston
Parasite-derived resistance

US6617496B1
(en)

1985-10-16
2003-09-09
Monsanto Company
Effecting virus resistance in plants through the use of negative strand RNAs

GB8601680D0
(en)

1986-01-23
1986-02-26
Agricultural Genetics Co
Modification of plant viruses

ATE119201T1
(en)

1986-04-02
1995-03-15
Pioneer Hi Bred Int

VIRUS RESISTANT PLANTS WITH A VIRAL COATING PROTEIN.

ATE124993T1
(en)

1986-04-02
1995-07-15
Pioneer Hi Bred Int

PLANTS RESISTANT TO THE VIRUS HAVING ANTI-SENS RNS.

KR950012900B1
(en)

*

1992-08-19
1995-10-23
주식회사진로
Expression vector for anti-virus protein gene

1986

1986-10-09
US
US06/917,027
patent/US6608241B1/en
not_active
Expired – Lifetime

1986-10-23
CA
CA000521247A
patent/CA1341565C/en
active
Active

1986-10-28
IE
IE282886A
patent/IE81098B1/en
not_active
IP Right Cessation

1986-10-28
AU
AU64528/86A
patent/AU608204B2/en
not_active
Expired

1986-10-28
IL
IL8043386A
patent/IL80433A/en
not_active
IP Right Cessation

1986-10-28
DK
DK515186A
patent/DK515186A/en
not_active
Application Discontinuation

1986-10-29
BG
BG76908A
patent/BG49720A3/en
unknown

1986-10-29
DE
DE3650507T
patent/DE3650507T2/en
not_active
Expired – Lifetime

1986-10-29
ES
ES86308397T
patent/ES2087055T3/en
not_active
Expired – Lifetime

1986-10-29
EP
EP86308397A
patent/EP0223452B1/en
not_active
Expired – Lifetime

1986-10-29
AT
AT86308397T
patent/ATE136330T1/en
not_active
IP Right Cessation

1994

1994-01-27
JP
JP6007601A
patent/JPH06339379A/en
active
Pending

1995

1995-07-10
JP
JP17377495A
patent/JP3281512B2/en
not_active
Expired – Fee Related

1996

1996-07-02
GR
GR960401811T
patent/GR3020438T3/en
unknown

1999

1999-07-28
JP
JP11214304A
patent/JP2000041512A/en
active
Pending

1999-11-19
JP
JP11330565A
patent/JP2000157288A/en
active
Pending

Cited By (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU603351B2
(en)

*

1986-01-23
1990-11-15
Agricultural Genetics Company Limited
Modification of plant viruses or their effects

AU612972B2
(en)

*

1986-04-02
1991-07-25
Pioneer Hi-Bred International, Inc.
Virus resistant plants having antisense rna

AU606382B2
(en)

*

1987-02-09
1991-02-07
Mycogen Plant Science, Inc.
Hybrid rna virus

Also Published As

Publication number
Publication date

IL80433A
(en)

1996-11-14

DK515186D0
(en)

1986-10-28

IE81098B1
(en)

2000-03-08

JP2000041512A
(en)

2000-02-15

DE3650507D1
(en)

1996-05-09

ES2087055T3
(en)

1996-07-16

EP0223452A2
(en)

1987-05-27

JPH06339379A
(en)

1994-12-13

JPH0851986A
(en)

1996-02-27

US6608241B1
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2003-08-19

IE862828L
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1987-04-29

GR3020438T3
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1996-10-31

AU608204B2
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1991-03-28

ATE136330T1
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1996-04-15

JP2000157288A
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2000-06-13

JP3281512B2
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2002-05-13

BG49720A3
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1992-01-15

DK515186A
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1987-04-30

EP0223452A3
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1989-08-30

DE3650507T2
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1996-10-17

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2007-12-04

EP0223452B1
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1996-04-03

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