AU6538286A – Process for the quantification of cell populations or subpopulations and a reagent suitable therefor
– Google Patents
AU6538286A – Process for the quantification of cell populations or subpopulations and a reagent suitable therefor
– Google Patents
Process for the quantification of cell populations or subpopulations and a reagent suitable therefor
Info
Publication number
AU6538286A
AU6538286A
AU65382/86A
AU6538286A
AU6538286A
AU 6538286 A
AU6538286 A
AU 6538286A
AU 65382/86 A
AU65382/86 A
AU 65382/86A
AU 6538286 A
AU6538286 A
AU 6538286A
AU 6538286 A
AU6538286 A
AU 6538286A
Authority
AU
Australia
Prior art keywords
cells
sample
subpopulations
quantification
cell populations
Prior art date
1985-11-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU65382/86A
Other versions
AU574281B2
(en
Inventor
Winfried Albert
Josef Endl
Hartmat Schetters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-11-19
Filing date
1986-11-19
Publication date
1987-05-21
1986-11-19
Application filed by Boehringer Mannheim GmbH
filed
Critical
Boehringer Mannheim GmbH
1987-05-21
Publication of AU6538286A
publication
Critical
patent/AU6538286A/en
1988-06-30
Application granted
granted
Critical
1988-06-30
Publication of AU574281B2
publication
Critical
patent/AU574281B2/en
2006-11-19
Anticipated expiration
legal-status
Critical
Status
Ceased
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 – G01N31/00
G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 – G01N31/00
G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N33/56966—Animal cells
G01N33/56972—White blood cells
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 – G01N31/00
G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N33/56966—Animal cells
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/81—Packaged device or kit
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/00—Chemistry: analytical and immunological testing
Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Abstract
A process for quantification of cell populations or subpopulations, by incubating a sample with labelled antibodies directed against characteristic surface antigens of the cell population to be quantified to form labelled antibody/antigen complexes. Standards with known, differing particle concentration and having comparable sedimentation behavior to the cells to be determined and further, carrying molecules which are directed against the labelled antibody or a part hereof are also incubated with the labelled antibodies. The cells of the sample solution, as well as the particles of the standard solution, are separated off from the excess labelled antibodies and the amount of the labelling is measured not only on the cells but also on the particles. By comparison of the measurement value from the sample with the measurement values from the standard solutions, there is ascertained the number of cells to be determined in the sample. The standard and a reagent kit for carrying out the process are also the subject of this application.
AU65382/86A
1985-11-19
1986-11-19
Process for the quantification of cell populations or subpopulations and a reagent suitable therefor
Ceased
AU574281B2
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
DE19853541033
DE3541033A1
(en)
1985-11-19
1985-11-19
METHOD FOR QUANTIFYING CELL POPULATIONS OR SUBPOPULATIONS AND REAGENT SUITABLE FOR THIS
DE3541033
1985-11-19
Publications (2)
Publication Number
Publication Date
AU6538286A
true
AU6538286A
(en)
1987-05-21
AU574281B2
AU574281B2
(en)
1988-06-30
Family
ID=6286390
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU65382/86A
Ceased
AU574281B2
(en)
1985-11-19
1986-11-19
Process for the quantification of cell populations or subpopulations and a reagent suitable therefor
Country Status (10)
Country
Link
US
(2)
US4876189A
(en)
EP
(1)
EP0224134B1
(en)
JP
(1)
JPS62121361A
(en)
KR
(1)
KR870005249A
(en)
AT
(1)
ATE50647T1
(en)
AU
(1)
AU574281B2
(en)
CA
(1)
CA1278258C
(en)
DE
(2)
DE3541033A1
(en)
IL
(1)
IL80655A0
(en)
ZA
(1)
ZA868569B
(en)
Families Citing this family (43)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US6159740A
(en)
*
1987-03-13
2000-12-12
Coulter Corporation
Method and apparatus for screening obscured or partially obscured cells
US5100777A
(en)
*
1987-04-27
1992-03-31
Tanox Biosystems, Inc.
Antibody matrix device and method for evaluating immune status
DE3736027A1
(en)
*
1987-10-24
1989-05-03
Gerhard Dipl Phys Artmann
Method for determining the shape of cells which prevails at a specific instant and device for carrying out the method
ES2035317T5
(en)
*
1987-11-09
1998-03-16
Becton Dickinson Co
METHOD FOR ANALYZING HEMATOPOYETIC CELLS IN A SAMPLE.
US5385822A
(en)
*
1988-05-02
1995-01-31
Zynaxis, Inc.
Methods for detection and quantification of cell subsets within subpopulations of a mixed cell population
US5256532A
(en)
*
1988-05-02
1993-10-26
Zynaxis Technologies, Inc.
Methods, reagents and test kits for determination of subpopulations of biological entities
FR2644894B1
(en)
*
1989-03-24
1994-05-13
Sanofi
ENZYMATIC DOSAGE KIT AND METHOD APPLICABLE TO WHOLE CELLS
FR2644893B1
(en)
*
1989-03-24
1991-07-12
Sanofi Sa
DOSAGE KIT AND METHOD APPLICABLE TO WHOLE CELLS
IE76732B1
(en)
*
1990-08-07
1997-11-05
Becton Dickinson Co
One step test for absolute counts
AU1533092A
(en)
*
1991-02-01
1992-09-07
Arizona Technology Development Corporation
Apparatus and methods for using hemozoin
US5459073A
(en)
*
1991-05-08
1995-10-17
Streck Laboratories, Inc.
Method and composition for preserving antigens and process for utilizing cytological material produced by same
US5849517A
(en)
*
1991-05-08
1998-12-15
Streck Laboratories, Inc.
Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5460797A
(en)
*
1991-05-08
1995-10-24
Streck Laboratories, Inc.
Method for fixing tissues and cells for analysis using oxazolidine compounds
CA2070244A1
(en)
*
1991-08-07
1993-02-08
Young Ran Kim
Method and reagent composition for subtyping lymphocytes in peripheral blood
ATE266195T1
(en)
1992-09-14
2004-05-15
Stanford Res Inst Int
UP-CONVERTING REPORTER MOLECULES FOR BIOLOGICAL AND OTHER TESTING PROCEDURES USING LASER EXCITATION TECHNIQUES
US5342754A
(en)
*
1992-09-14
1994-08-30
Coulter Corporation
Preserved, non-infectious control cell for use in the identification of a disease through blood testing
US5585246A
(en)
*
1993-02-17
1996-12-17
Biometric Imaging, Inc.
Method for preparing a sample in a scan capillary for immunofluorescent interrogation
US5409826A
(en)
*
1993-06-08
1995-04-25
Coulter Corporation
Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
JPH08330818A
(en)
*
1995-05-27
1996-12-13
Nec Corp
Snow melting device for parabolic antenna
DE19725133A1
(en)
*
1997-06-13
1998-12-17
Micromet Ges Fuer Biomedizinis
Immuno-cyto-chemical detection of target cells
US6759246B1
(en)
2001-11-30
2004-07-06
Research & Diagnostic Systems, Inc.
Hematology control composition including lymphocyte analogs and method for preparation and use
JP4748719B2
(en)
*
2006-03-02
2011-08-17
国立大学法人大阪大学
Methods for quantifying specific proteins in living cells and preparing standard fluorescent microbeads
AU2009311588B2
(en)
2008-11-07
2016-07-28
Adaptive Biotechnologies Corp.
Methods of monitoring conditions by sequence analysis
US8748103B2
(en)
2008-11-07
2014-06-10
Sequenta, Inc.
Monitoring health and disease status using clonotype profiles
US9528160B2
(en)
2008-11-07
2016-12-27
Adaptive Biotechnolgies Corp.
Rare clonotypes and uses thereof
US9506119B2
(en)
2008-11-07
2016-11-29
Adaptive Biotechnologies Corp.
Method of sequence determination using sequence tags
US9365901B2
(en)
2008-11-07
2016-06-14
Adaptive Biotechnologies Corp.
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US8628927B2
(en)
2008-11-07
2014-01-14
Sequenta, Inc.
Monitoring health and disease status using clonotype profiles
EP2387627B1
(en)
2009-01-15
2016-03-30
Adaptive Biotechnologies Corporation
Adaptive immunity profiling and methods for generation of monoclonal antibodies
WO2010151416A1
(en)
2009-06-25
2010-12-29
Fred Hutchinson Cancer Research Center
Method of measuring adaptive immunity
US10385475B2
(en)
2011-09-12
2019-08-20
Adaptive Biotechnologies Corp.
Random array sequencing of low-complexity libraries
EP2768982A4
(en)
2011-10-21
2015-06-03
Adaptive Biotechnologies Corp
Quantification of adaptive immune cell genomes in a complex mixture of cells
EP2788509B1
(en)
2011-12-09
2018-07-11
Adaptive Biotechnologies Corporation
Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2
(en)
2011-12-13
2016-11-22
Adaptive Biotechnologies Corp.
Detection and measurement of tissue-infiltrating lymphocytes
EP3372694A1
(en)
2012-03-05
2018-09-12
Adaptive Biotechnologies Corporation
Determining paired immune receptor chains from frequency matched subunits
US9150905B2
(en)
2012-05-08
2015-10-06
Adaptive Biotechnologies Corporation
Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions
ES2660027T3
(en)
2012-10-01
2018-03-20
Adaptive Biotechnologies Corporation
Evaluation of immunocompetence by the diversity of adaptive immunity receptors and clonal characterization
US10150996B2
(en)
2012-10-19
2018-12-11
Adaptive Biotechnologies Corp.
Quantification of adaptive immune cell genomes in a complex mixture of cells
US9708657B2
(en)
2013-07-01
2017-07-18
Adaptive Biotechnologies Corp.
Method for generating clonotype profiles using sequence tags
CA2941612A1
(en)
2014-03-05
2015-09-11
Adaptive Biotechnologies Corporation
Methods using randomer-containing synthetic molecules
US10066265B2
(en)
2014-04-01
2018-09-04
Adaptive Biotechnologies Corp.
Determining antigen-specific t-cells
EP3212790B1
(en)
2014-10-29
2020-03-25
Adaptive Biotechnologies Corp.
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10246701B2
(en)
2014-11-14
2019-04-02
Adaptive Biotechnologies Corp.
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
Family Cites Families (12)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU531777B2
(en)
*
1978-04-05
1983-09-08
Syva Co.
Label/solid conjugate immunoassay system
US4381295A
(en)
*
1979-04-26
1983-04-26
Ortho Pharmaceutical Corporation
Monoclonal antibody to human helper T cells and methods of preparing same
US4284412A
(en)
*
1979-07-13
1981-08-18
Ortho Diagnostics, Inc.
Method and apparatus for automated identification and enumeration of specified blood cell subclasses
JPS56141559A
(en)
*
1980-04-04
1981-11-05
Toray Ind Inc
Reagent for immunological inspection
US4486530A
(en)
*
1980-08-04
1984-12-04
Hybritech Incorporated
Immunometric assays using monoclonal antibodies
EP0054685B1
(en)
*
1980-12-23
1986-07-09
Roche Diagnostics GmbH
Hydrophilic latex particles, process for their preparation and their use
US4511662A
(en)
*
1982-06-18
1985-04-16
Bio-Rad Laboratories, Inc.
Simultaneous assay for T and B lymphocyte populations and subpopulations
US4614722A
(en)
*
1983-11-01
1986-09-30
Pasula Mark J
Method and apparatus for measuring the degree of reaction between antigens and leukocyte cellular antibodies
US4745075A
(en)
*
1984-09-06
1988-05-17
Burroughs Wellcome Co.
Diagnostic test methods
US4828984A
(en)
*
1986-04-11
1989-05-09
Flow Cytometry Standards Corporation
Composition, synthesis and use of simulated cells
US4720465A
(en)
*
1985-05-14
1988-01-19
Fisher Scientific Company
Centrifugal kinetic agglutination assay
US4714682A
(en)
*
1985-12-11
1987-12-22
Flow Cytometry Standards Corporation
Fluorescent calibration microbeads simulating stained cells
1985
1985-11-19
DE
DE19853541033
patent/DE3541033A1/en
not_active
Withdrawn
1986
1986-10-31
CA
CA000521967A
patent/CA1278258C/en
not_active
Expired – Lifetime
1986-11-05
US
US06/927,803
patent/US4876189A/en
not_active
Expired – Lifetime
1986-11-12
ZA
ZA868569A
patent/ZA868569B/en
unknown
1986-11-13
DE
DE8686115758T
patent/DE3669206D1/en
not_active
Expired – Lifetime
1986-11-13
EP
EP86115758A
patent/EP0224134B1/en
not_active
Expired – Lifetime
1986-11-13
AT
AT86115758T
patent/ATE50647T1/en
not_active
IP Right Cessation
1986-11-16
IL
IL80655A
patent/IL80655A0/en
not_active
IP Right Cessation
1986-11-18
JP
JP61273082A
patent/JPS62121361A/en
active
Granted
1986-11-19
KR
KR860009778A
patent/KR870005249A/en
not_active
Application Discontinuation
1986-11-19
AU
AU65382/86A
patent/AU574281B2/en
not_active
Ceased
1989
1989-07-07
US
US07/376,707
patent/US5094940A/en
not_active
Expired – Fee Related
Also Published As
Publication number
Publication date
DE3669206D1
(en)
1990-04-05
US5094940A
(en)
1992-03-10
EP0224134A1
(en)
1987-06-03
JPH0521508B2
(en)
1993-03-24
JPS62121361A
(en)
1987-06-02
KR870005249A
(en)
1987-06-05
EP0224134B1
(en)
1990-02-28
AU574281B2
(en)
1988-06-30
ATE50647T1
(en)
1990-03-15
ZA868569B
(en)
1987-07-29
CA1278258C
(en)
1990-12-27
DE3541033A1
(en)
1987-05-21
IL80655A0
(en)
1987-02-27
US4876189A
(en)
1989-10-24
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