AU6661086A - Creation of Inventions and Patents with Artificial Intelligence

AU6661086A – Stabilised human tissue plasminogen activator compositions
– Google Patents

AU6661086A – Stabilised human tissue plasminogen activator compositions
– Google Patents
Stabilised human tissue plasminogen activator compositions

Info

Publication number
AU6661086A

AU6661086A
AU66610/86A
AU6661086A
AU6661086A
AU 6661086 A
AU6661086 A
AU 6661086A
AU 66610/86 A
AU66610/86 A
AU 66610/86A
AU 6661086 A
AU6661086 A
AU 6661086A
AU 6661086 A
AU6661086 A
AU 6661086A
Authority
AU
Australia
Prior art keywords
plasminogen activator
human tissue
tissue plasminogen
activator compositions
stabilised
Prior art date
1985-12-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
AU66610/86A
Other versions

AU600246B2
(en

Inventor
William Franklin Bennett
Stuart E. Builder
Larry Alan Gatlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Genentech Inc

Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1985-12-17
Filing date
1986-12-16
Publication date
1987-06-18
Family has litigation

First worldwide family litigation filed
litigation
Critical
https://patents.darts-ip.com/?family=25205495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU6661086(A)
“Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-12-16
Application filed by Genentech Inc
filed
Critical
Genentech Inc

1987-06-18
Publication of AU6661086A
publication
Critical
patent/AU6661086A/en

1990-08-09
Application granted
granted
Critical

1990-08-09
Publication of AU600246B2
publication
Critical
patent/AU600246B2/en

2006-12-16
Anticipated expiration
legal-status
Critical

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K38/00—Medicinal preparations containing peptides

A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

A61K38/43—Enzymes; Proenzymes; Derivatives thereof

A61K38/46—Hydrolases (3)

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/0012—Galenical forms characterised by the site of application

A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K38/00—Medicinal preparations containing peptides

A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

A61K38/43—Enzymes; Proenzymes; Derivatives thereof

A61K38/46—Hydrolases (3)

A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)

A61K38/49—Urokinase; Tissue plasminogen activator

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates

A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P7/00—Drugs for disorders of the blood or the extracellular fluid

A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Abstract

Stable pharmaceutically acceptable compositions containing human tissue plasminogen activator featuring, for example, an argininium ion containing buffer as a component.

AU66610/86A
1985-12-17
1986-12-16
Stabilised human tissue plasminogen activator compositions

Expired

AU600246B2
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

US06/811,081

US4777043A
(en)

1985-12-17
1985-12-17
Stabilized human tissue plasminogen activator compositions

US811081

1985-12-17

Publications (2)

Publication Number
Publication Date

AU6661086A
true

AU6661086A
(en)

1987-06-18

AU600246B2

AU600246B2
(en)

1990-08-09

Family
ID=25205495
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

AU66610/86A
Expired

AU600246B2
(en)

1985-12-17
1986-12-16
Stabilised human tissue plasminogen activator compositions

Country Status (23)

Country
Link

US
(2)

US4777043A
(en)

EP
(1)

EP0228862B1
(en)

JP
(2)

JPH0714886B2
(en)

KR
(1)

KR950010322B1
(en)

AT
(1)

ATE79273T1
(en)

AU
(1)

AU600246B2
(en)

DD
(1)

DD255477A5
(en)

DE
(2)

DE3642960A1
(en)

DK
(1)

DK174203B1
(en)

ES
(1)

ES2044840T3
(en)

FI
(1)

FI88873C
(en)

FR
(1)

FR2591485B1
(en)

GB
(1)

GB2184354B
(en)

GR
(1)

GR3006078T3
(en)

HU
(1)

HU200101B
(en)

IE
(1)

IE59060B1
(en)

IL
(1)

IL80904A
(en)

MY
(1)

MY102185A
(en)

NO
(1)

NO168988C
(en)

NZ
(1)

NZ218612A
(en)

PH
(1)

PH24716A
(en)

PT
(1)

PT83933B
(en)

ZA
(1)

ZA869457B
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU625307B2
(en)

1989-12-20
1992-07-09
Boehringer Mannheim Gmbh
Stabilization of k2p pro

Families Citing this family (27)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE3687255T2
(en)

1985-09-10
1993-05-06
Eisai Co Ltd

COMPOSITION CONTAINING A TISSUE PLASMINOGEN ACTIVATOR.

JPH0672105B2
(en)

1985-10-02
1994-09-14
持田製薬株式会社

Thrombolytic agent and manufacturing method thereof

US5453363A
(en)

1985-10-23
1995-09-26
Boehringer Mannheim Gmbh
Process for the activation of t-PA or Ing after genetic expression in prokaryotes

US5034225A
(en)

1985-12-17
1991-07-23
Genentech Inc.
Stabilized human tissue plasminogen activator compositions

JP2708749B2
(en)

1987-08-10
1998-02-04
エーザイ株式会社

Injectable composition containing modified tPA

DE3877529T2
(en)

1987-10-23
1996-11-07
Centre Regional De Transfusion

Production of highly purified human factor IX and other plasma protein concentrate and its therapeutic use.

US4898826A
(en)

1987-12-10
1990-02-06
Invitron Corporation
Method to solubilize tissue plasminogen activator

HU206367B
(en)

1988-04-30
1992-10-28
Sandoz Ag
Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts

US4980165A
(en)

1989-01-27
1990-12-25
Genetics Institute, Inc.
Pharmaceutical formulations of plasminogen activator proteins

DE3903581A1
(en)

1989-02-07
1990-08-16
Boehringer Mannheim Gmbh

FABRIC PLASMINOGEN ACTIVATOR DERIVATIVE

JP2520975B2
(en)

1989-09-21
1996-07-31
三井東圧化学株式会社

Thrombolytic agent containing tissue plasminogen activator or its derivative

US6207151B1
(en)

1989-09-21
2001-03-27
Mitsui Chemicals Inc.
Aqueous solution of t-PA

DE3942145A1
(en)

1989-12-20
1991-06-27
Boehringer Mannheim Gmbh

T-PA SOLUBILIZATION

DE3942142A1
(en)

1989-12-20
1991-06-27
Boehringer Mannheim Gmbh

STABILIZATION OF GLYCOSYLATED T-PA

DE3942143A1
(en)

1989-12-20
1991-06-27
Boehringer Mannheim Gmbh

T-PA PRO STABILIZATION

DE3942144A1
(en)

1989-12-20
1991-06-27
Boehringer Mannheim Gmbh

STABILIZATION OF K1K2P PRO

US5358708A
(en)

1993-01-29
1994-10-25
Schering Corporation
Stabilization of protein formulations

US5656730A
(en)

1995-04-07
1997-08-12
Enzon, Inc.
Stabilized monomeric protein compositions

DE19606551C2
(en)

1996-02-22
2000-06-08
Basotherm Gmbh

rt-PA for the prevention of cataract after cataract surgery

US5972912A
(en)

1998-12-17
1999-10-26
S.P. Pharmaceuticals
Method for lyophilizing ifosfamide

DE60009926T2
(en)

1999-08-17
2005-04-07
Novo Nordisk Health Care Ag

STABILIZATION OF FREEZE-DRIED CAKE

US6586574B1
(en)

1999-08-17
2003-07-01
Nn A/S
Stabilization of freeze-dried cake

AU781023B2
(en)

1999-11-04
2005-04-28
Genentech Inc.
Reversed-phase HPLC assay for plasminogen activators

AU4458401A
(en)

2000-03-31
2001-10-15
Kirin Brewery
Powdery preparation for transmucosal administration containing a polymeric form of drug and exhibiting improved storage stability

CA2459120A1
(en)

2001-09-07
2003-03-20
Kenneth S. S. Chang
Human tissue urokinase type plasminogen activator formulation

US20110179558A1
(en)

2009-07-29
2011-07-28
International Enviroguard Systems, Inc.
Breathable Protective Fabric and Garment

EP3693021A1
(en)

2013-03-14
2020-08-12
Allergan, Inc.
Composition of a sustained-release delivery and method of stabilizing proteins during fabrication process

Family Cites Families (13)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DK98833C
(en)

1961-04-25
1964-05-25
Novo Terapeutisk Labor As

Method for stabilizing therapeutically useful plasmin solutions.

EP0112940B1
(en)

1982-12-30
1986-10-15
Kowa Company, Ltd.
Method of producing a tissue plasminogen activator and composition comprising same

JPS59196824A
(en)

1983-04-21
1984-11-08
Kowa Co
Adsorption inhibitor

EP0156169B1
(en)

1984-02-29
1991-12-18
Asahi Kasei Kogyo Kabushiki Kaisha
An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method

NO175216C
(en)

1985-04-22
1994-09-14
Genentech Inc

Method of Preparation of Human Tissue Plasminogen Activator, DNA Sequence, Replicable Expression Vector and Cell Culture

US4929444A
(en)

1985-05-28
1990-05-29
Burroughs Wellcome Co.
Low pH pharmaceutical formulation containing t-PA

HU200695B
(en)

1985-05-28
1990-08-28
Wellcome Found
Process for producing stable pharmaceutical compositions comprising tissural plasminogene activator

ZW14486A1
(en)

1985-07-29
1986-10-22
Smithkline Beckman Corp
Pharmaceutical dosage unit

DE3687255T2
(en)

1985-09-10
1993-05-06
Eisai Co Ltd

COMPOSITION CONTAINING A TISSUE PLASMINOGEN ACTIVATOR.

JPH0672105B2
(en)

1985-10-02
1994-09-14
持田製薬株式会社

Thrombolytic agent and manufacturing method thereof

DE3537708A1
(en)

1985-10-23
1987-04-23
Boehringer Mannheim Gmbh

METHOD FOR ACTIVATING T-PA AFTER EXPRESSION IN PROKARYONTS

JPS62120321A
(en)

1985-11-20
1987-06-01
Eisai Co Ltd
Tpa-containing pharmaceutical composition

JPS62283932A
(en)

1986-05-29
1987-12-09
Green Cross Corp:The
Dry pharmaceutical of tissue plasminogen activator

1985

1985-12-17
US
US06/811,081
patent/US4777043A/en
not_active
Expired – Lifetime

1986

1986-12-08
IL
IL80904A
patent/IL80904A/en
not_active
IP Right Cessation

1986-12-12
NZ
NZ218612A
patent/NZ218612A/en
unknown

1986-12-15
PT
PT83933A
patent/PT83933B/en
unknown

1986-12-16
DE
DE19863642960
patent/DE3642960A1/en
not_active
Ceased

1986-12-16
DE
DE8686309811T
patent/DE3686410T2/en
not_active
Expired – Lifetime

1986-12-16
NO
NO865079A
patent/NO168988C/en
not_active
IP Right Cessation

1986-12-16
GB
GB8629981A
patent/GB2184354B/en
not_active
Revoked

1986-12-16
PH
PH34602A
patent/PH24716A/en
unknown

1986-12-16
HU
HU865225A
patent/HU200101B/en
unknown

1986-12-16
IE
IE327986A
patent/IE59060B1/en
not_active
IP Right Cessation

1986-12-16
EP
EP86309811A
patent/EP0228862B1/en
not_active
Expired – Lifetime

1986-12-16
DK
DK198606057A
patent/DK174203B1/en
not_active
IP Right Cessation

1986-12-16
DD
DD86297695A
patent/DD255477A5/en
unknown

1986-12-16
ES
ES86309811T
patent/ES2044840T3/en
not_active
Expired – Lifetime

1986-12-16
FR
FR8617593A
patent/FR2591485B1/en
not_active
Expired

1986-12-16
AU
AU66610/86A
patent/AU600246B2/en
not_active
Expired

1986-12-16
KR
KR1019860010747A
patent/KR950010322B1/en
not_active
IP Right Cessation

1986-12-16
AT
AT86309811T
patent/ATE79273T1/en
not_active
IP Right Cessation

1986-12-17
JP
JP61302767A
patent/JPH0714886B2/en
not_active
Expired – Lifetime

1986-12-17
FI
FI865159A
patent/FI88873C/en
not_active
IP Right Cessation

1986-12-17
ZA
ZA869457A
patent/ZA869457B/en
unknown

1987

1987-10-01
MY
MYPI87002760A
patent/MY102185A/en
unknown

1988

1988-03-28
US
US07/173,854
patent/US4908205A/en
not_active
Expired – Lifetime

1992

1992-10-26
GR
GR920402407T
patent/GR3006078T3/el
unknown

1994

1994-08-04
JP
JP6183274A
patent/JPH07173076A/en
active
Pending

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

AU625307B2
(en)

1989-12-20
1992-07-09
Boehringer Mannheim Gmbh
Stabilization of k2p pro

Also Published As

Publication number
Publication date

ATE79273T1
(en)

1992-08-15

GB2184354A
(en)

1987-06-24

EP0228862A2
(en)

1987-07-15

FI88873B
(en)

1993-04-15

EP0228862A3
(en)

1988-09-28

NO168988B
(en)

1992-01-20

IE59060B1
(en)

1993-12-15

GR3006078T3
(en)

1993-06-21

DD255477A5
(en)

1988-04-06

NO865079L
(en)

1987-06-18

JPS62164632A
(en)

1987-07-21

DE3642960A1
(en)

1987-06-19

GB2184354B
(en)

1990-04-11

FI88873C
(en)

1993-07-26

DK605786A
(en)

1987-06-18

GB8629981D0
(en)

1987-01-28

PT83933A
(en)

1987-01-01

DK605786D0
(en)

1986-12-16

KR950010322B1
(en)

1995-09-14

US4908205A
(en)

1990-03-13

JPH0714886B2
(en)

1995-02-22

US4777043A
(en)

1988-10-11

DK174203B1
(en)

2002-09-16

DE3686410T2
(en)

1993-02-18

PT83933B
(en)

1989-01-17

MY102185A
(en)

1992-04-30

NZ218612A
(en)

1989-07-27

DE3686410D1
(en)

1992-09-17

IL80904A0
(en)

1987-03-31

FR2591485B1
(en)

1989-07-28

HU200101B
(en)

1990-04-28

HUT42955A
(en)

1987-09-28

IE863279L
(en)

1987-06-17

AU600246B2
(en)

1990-08-09

JPH07173076A
(en)

1995-07-11

NO168988C
(en)

1992-04-29

NO865079D0
(en)

1986-12-16

EP0228862B1
(en)

1992-08-12

PH24716A
(en)

1990-10-01

ES2044840T3
(en)

1994-01-16

ZA869457B
(en)

1988-08-31

FI865159A
(en)

1987-06-18

FI865159A0
(en)

1986-12-17

KR870005647A
(en)

1987-07-06

IL80904A
(en)

1992-01-15

FR2591485A1
(en)

1987-06-19

Contact information