AU6957991A – Chromogenic substrate
– Google Patents
AU6957991A – Chromogenic substrate
– Google Patents
Chromogenic substrate
Info
Publication number
AU6957991A
AU6957991A
AU69579/91A
AU6957991A
AU6957991A
AU 6957991 A
AU6957991 A
AU 6957991A
AU 69579/91 A
AU69579/91 A
AU 69579/91A
AU 6957991 A
AU6957991 A
AU 6957991A
AU 6957991 A
AU6957991 A
AU 6957991A
Authority
AU
Australia
Prior art keywords
pct
peptide derivatives
date jun
glyc
lys
Prior art date
1989-12-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU69579/91A
Inventor
Salo Arielly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KABI DIAGNOSTICA AB
Original Assignee
Kabi Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1989-12-12
Filing date
1990-12-03
Publication date
1991-07-18
1990-12-03
Application filed by Kabi Pharmacia AB
filed
Critical
Kabi Pharmacia AB
1991-07-18
Publication of AU6957991A
publication
Critical
patent/AU6957991A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
239000003593
chromogenic compound
Substances
0.000
title
1
108090000765
processed proteins & peptides
Proteins
0.000
abstract
3
HSRJKNPTNIJEKV-UHFFFAOYSA-N
Guaifenesin
Chemical compound
COC1=CC=CC=C1OCC(O)CO
HSRJKNPTNIJEKV-UHFFFAOYSA-N
0.000
abstract
2
239000002158
endotoxin
Substances
0.000
abstract
2
238000000034
method
Methods
0.000
abstract
2
TYMLOMAKGOJONV-UHFFFAOYSA-N
4-nitroaniline
Chemical group
NC1=CC=C([N+]([O-])=O)C=C1
TYMLOMAKGOJONV-UHFFFAOYSA-N
0.000
abstract
1
125000006239
protecting group
Chemical group
0.000
abstract
1
150000003839
salts
Chemical class
0.000
abstract
1
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
C07K5/10—Tetrapeptides
C07K5/1002—Tetrapeptides with the first amino acid being neutral
C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
Y02P20/00—Technologies relating to chemical industry
Y02P20/50—Improvements relating to the production of bulk chemicals
Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
PCT No. PCT/SE90/00797 Sec. 371 Date Jun. 11, 1992 Sec. 102(e) Date Jun. 11, 1992 PCT Filed Dec. 3, 1990 PCT Pub. No. WO91/09052 PCT Pub. Date Jun. 27, 1991.The invention relates to, novel peptide derivatives with the formula: R1-A1-A2-A3-A4-R2 or its salt, wherein R1=H or a protective group, A1=H, Ile, Leu or Val, A2=Glu, Asp, Ser, Thr; A3=Gly or Glyc; A4=Arg or Lys; R2=4-nitroaniline with the proviso that A3 is Gly when A4 is Lys and that A3 is Glyc when A4 is Arg. The invention also discloses the process for the preparation of the peptide derivatives, the method for the determination of the bacterial endotoxins by the use of the invented peptide derivatives and the use of these derivatives for determination of bacterial endotoxins.
AU69579/91A
1989-12-12
1990-12-03
Chromogenic substrate
Abandoned
AU6957991A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
SE8904188
1989-12-12
SE8904188A
SE8904188D0
(en)
1989-12-12
1989-12-12
CHROMOGENIC SUBSTRATE
Publications (1)
Publication Number
Publication Date
AU6957991A
true
AU6957991A
(en)
1991-07-18
Family
ID=20377747
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU69579/91A
Abandoned
AU6957991A
(en)
1989-12-12
1990-12-03
Chromogenic substrate
Country Status (9)
Country
Link
US
(1)
US5334703A
(en)
EP
(1)
EP0505428B1
(en)
JP
(1)
JP2929555B2
(en)
AT
(1)
ATE149516T1
(en)
AU
(1)
AU6957991A
(en)
DE
(1)
DE69030102T2
(en)
ES
(1)
ES2098344T3
(en)
SE
(1)
SE8904188D0
(en)
WO
(1)
WO1991009052A1
(en)
Families Citing this family (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0549102B1
(en)
*
1991-12-25
1996-07-03
Maruha Corporation
Beta-glucans detection reagents and methods of detecting beta-glucans
DE10251894A1
(en)
*
2002-11-07
2004-05-19
C-Cit Ag
New peptide-containing benzophenoxazine or napthoquinone derivatives, useful as chromogenic substrates for enzymes, e.g. for diagnosis, monitoring therapy and detecting pyrogens
Family Cites Families (13)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3759218A
(en)
*
1971-08-03
1973-09-18
H Korstvedt
Breading apparatus
JPS5415797A
(en)
*
1977-06-14
1979-02-05
Seikagaku Kogyo Co Ltd
Detection and measurement of toxin in cells
SE7801373L
(en)
*
1978-02-07
1979-08-08
Kabi Ab
EASY SPLABLE SUBSTRATE FOR QUANTIFIATION OF PROTEASES
US4244865A
(en)
*
1979-12-03
1981-01-13
Abbott Laboratories
α hydroxy tripeptide substrates
DE3164437D1
(en)
*
1980-08-25
1984-08-02
Kabivitrum Ab
Peptide substrates for determination of protease activity
US4563305A
(en)
*
1981-01-07
1986-01-07
University Of Miami
Radiolabelled substrates for assaying mammalian enzymes
FR2497798A1
(en)
*
1981-01-09
1982-07-16
Pharmindustrie
NOVEL PEPTIDES CARRYING A FLUOROPHORE, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION TO FLUORIMETRIC DETERMINATION OF ENDOTOXINS
US4510241A
(en)
*
1981-09-03
1985-04-09
Mallinckrodt, Inc.
Peptide-type substrates useful in the quantitative determination of endotoxin
JPS5885162A
(en)
*
1981-11-16
1983-05-21
Seikagaku Kogyo Co Ltd
Endotoxine measurement
SE431228B
(en)
*
1981-12-17
1984-01-23
Kenneth Soderhell
SETTING FOR DETERMINATION OF BACTERIAL ENDOTOXIN MEDIUM PROPHENOLOXIDAS-CONTAINING ANIMAL ANIMAL OR INSECTS AND REAGENTS
DE3244030A1
(en)
*
1982-11-27
1984-05-30
Behringwerke Ag, 3550 Marburg
CHROMOGENIC COMPOUNDS, METHOD FOR THEIR PRODUCTION AND THEIR USE
JPS62236474A
(en)
*
1986-04-08
1987-10-16
San Plant Kogyo Kk
Flour attaching automatic machine
JPS62294027A
(en)
*
1986-06-11
1987-12-21
サン・プラント工業株式会社
Roller type powder feeder
1989
1989-12-12
SE
SE8904188A
patent/SE8904188D0/en
unknown
1990
1990-12-03
JP
JP3501386A
patent/JP2929555B2/en
not_active
Expired – Lifetime
1990-12-03
DE
DE69030102T
patent/DE69030102T2/en
not_active
Expired – Fee Related
1990-12-03
ES
ES91900986T
patent/ES2098344T3/en
not_active
Expired – Lifetime
1990-12-03
AT
AT91900986T
patent/ATE149516T1/en
not_active
IP Right Cessation
1990-12-03
US
US07/859,717
patent/US5334703A/en
not_active
Expired – Fee Related
1990-12-03
AU
AU69579/91A
patent/AU6957991A/en
not_active
Abandoned
1990-12-03
EP
EP91900986A
patent/EP0505428B1/en
not_active
Expired – Lifetime
1990-12-03
WO
PCT/SE1990/000797
patent/WO1991009052A1/en
active
IP Right Grant
Also Published As
Publication number
Publication date
JPH05506209A
(en)
1993-09-16
EP0505428A1
(en)
1992-09-30
US5334703A
(en)
1994-08-02
ATE149516T1
(en)
1997-03-15
ES2098344T3
(en)
1997-05-01
DE69030102D1
(en)
1997-04-10
DE69030102T2
(en)
1997-07-17
JP2929555B2
(en)
1999-08-03
EP0505428B1
(en)
1997-03-05
SE8904188D0
(en)
1989-12-12
WO1991009052A1
(en)
1991-06-27
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