AU7456691A – Mercaptoacyl aminolactam endopeptidase inhibitors
– Google Patents
AU7456691A – Mercaptoacyl aminolactam endopeptidase inhibitors
– Google Patents
Mercaptoacyl aminolactam endopeptidase inhibitors
Info
Publication number
AU7456691A
AU7456691A
AU74566/91A
AU7456691A
AU7456691A
AU 7456691 A
AU7456691 A
AU 7456691A
AU 74566/91 A
AU74566/91 A
AU 74566/91A
AU 7456691 A
AU7456691 A
AU 7456691A
AU 7456691 A
AU7456691 A
AU 7456691A
Authority
AU
Australia
Prior art keywords
aminolactam
mercaptoacyl
endopeptidase inhibitors
endopeptidase
inhibitors
Prior art date
1990-03-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU74566/91A
Inventor
Bernard R. Neustadt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1990-03-09
Filing date
1991-03-07
Publication date
1991-10-10
1991-03-07
Application filed by Schering Corp
filed
Critical
Schering Corp
1991-10-10
Publication of AU7456691A
publication
Critical
patent/AU7456691A/en
Status
Abandoned
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
C07D211/74—Oxygen atoms
C07D211/76—Oxygen atoms attached in position 2 or 6
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P13/00—Drugs for disorders of the urinary system
A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P15/00—Drugs for genital or sexual disorders; Contraceptives
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P3/00—Drugs for disorders of the metabolism
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/12—Antihypertensives
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D223/12—Nitrogen atoms not forming part of a nitro radical
AU74566/91A
1990-03-09
1991-03-07
Mercaptoacyl aminolactam endopeptidase inhibitors
Abandoned
AU7456691A
(en)
Applications Claiming Priority (2)
Application Number
Priority Date
Filing Date
Title
US07/491,148
US5075302A
(en)
1990-03-09
1990-03-09
Mercaptoacyl aminolactam endopeptidase inhibitors
US491148
1990-03-09
Publications (1)
Publication Number
Publication Date
AU7456691A
true
AU7456691A
(en)
1991-10-10
Family
ID=23950990
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
AU74566/91A
Abandoned
AU7456691A
(en)
1990-03-09
1991-03-07
Mercaptoacyl aminolactam endopeptidase inhibitors
Country Status (6)
Country
Link
US
(1)
US5075302A
(en)
EP
(1)
EP0518943A1
(en)
JP
(1)
JPH0688969B2
(en)
AU
(1)
AU7456691A
(en)
CA
(1)
CA2077746A1
(en)
WO
(1)
WO1991013870A1
(en)
Families Citing this family (23)
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Title
WO1992007568A1
(en)
*
1990-11-01
1992-05-14
Smithkline Beecham Corporation
η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS
US5244889A
(en)
*
1991-11-26
1993-09-14
Ciba-Geigy Corporation
Certain macrocyclic lactam derivatives
WO1993010773A1
(en)
*
1991-12-06
1993-06-10
Schering-Plough S.P.A.
Use of neutral endopeptidase inhibitors in the treatment of left ventricular hypertrophy
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1992-05-18
1996-09-03
E. R. Squibb & Sons, Inc.
Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
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1992-10-28
1996-04-02
Bristol-Myers Squibb Co.
Benzo-fused lactams
US6034247A
(en)
*
1993-02-17
2000-03-07
The Trustees Of The University Of Pennsylvania
Oxazolidinones and methods for the synthesis and use of same
US5489692A
(en)
*
1993-02-17
1996-02-06
The Trustees Of The University Of Pennsylvania
Pyrrolinone-based compounds
US5514814A
(en)
*
1993-02-17
1996-05-07
Trustees Of The University Of Pennsylvania
Pyrrolinone-based compounds
US5770732A
(en)
*
1993-02-17
1998-06-23
The Trustees Of The University Of Pennsylvania
Pyrrolinone-based peptidomimetics
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1993-05-13
1997-08-05
Bristol-Myers Squibb
Spiro lactam dual action inhibitors
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1993-06-15
1996-04-16
Bristol-Myers Squibb Company
Compounds containing a fused bicycle ring and processes therefor
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1993-07-06
1993-11-15
Univ Ramot
Compositions and method for modulating fertility
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*
1993-07-26
1994-11-08
Bristol-Myers Squibb
Substituted azepino[2,1-a]isoquinoline compounds
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*
1993-11-18
1996-06-11
Bristol-Myers Squibb Co.
Compounds containing a fused multiple ring lactam
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*
1994-05-05
1997-04-01
Bristol-Myers Squibb Co.
Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
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*
1995-02-17
1996-12-24
Bristol-Myers Squibb Company
Azepinone compounds useful in the inhibition of ACE and NEP
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*
1995-03-21
1997-09-30
The Procter & Gamble Company
Lactam-containing hydroxamic acids
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1995-05-17
1999-03-02
Bristol-Myers Squibb
Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
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*
1995-06-07
1997-07-22
Karanewsky; Donald S.
Thiazolo benzazepine containing dual action inhibitors
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1995-06-07
1997-06-03
Bristol-Myers Squibb Co.
Diazepine containing dual action inhibitors
US20040186071A1
(en)
1998-04-13
2004-09-23
Bennett C. Frank
Antisense modulation of CD40 expression
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(en)
1998-12-31
2004-08-03
Aventis Pharmaceuticals Inc.
1-Carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of MMP-12
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(en)
2007-11-20
2014-12-23
Isis Pharmaceuticals, Inc.
Modulation of CD40 expression
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1976-06-21
1978-08-08
E. R. Squibb & Sons, Inc.
Proline derivatives and related compounds
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1978-12-11
1983-03-31
Merck & Co Inc
Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
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*
1979-07-13
1981-03-17
Usv Pharmaceutical Corporation
Antihypertensive amides
US4508729A
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*
1979-12-07
1985-04-02
Adir
Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
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(en)
*
1980-10-06
1982-09-21
Warner-Lambert Company
Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
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*
1980-04-11
1984-02-29
The Wellcome Foundation Limited
Pharmaceutical amides, and preparation, formulations and use thereof
FR2480747A1
(en)
*
1980-04-17
1981-10-23
Roques Bernard
AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
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1980-08-30
1994-06-09
Hoechst Ag
Amino acid derivatives, processes for their preparation, compositions containing them and their use.
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1982-08-17
Warner-Lambert Company
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
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Carboxyalkyl dipeptides Process for their preparation and medicaments containing them
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1981-04-28
1984-09-11
Schering Corporation
7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids
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1983-02-22
Ciba-Geigy Corporation
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DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (3.3.0) -OCTAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THE USE THEREOF
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*
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*
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*
1981-12-24
1985-11-26
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Phosphorus containing compounds and use as hypotensives
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(en)
*
1982-05-12
1985-05-22
Hoffmann La Roche
Diaza-bicyclic compounds
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(en)
*
1982-06-14
1984-08-28
E. R. Squibb & Sons, Inc.
Esters of phosphinylalkanoyl substituted prolines
US4470973A
(en)
*
1982-07-19
1984-09-11
E. R. Squibb & Sons, Inc.
Substituted peptide compounds
US4552889A
(en)
*
1983-06-09
1985-11-12
Eli Lilly And Company
3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4774256A
(en)
*
1983-10-03
1988-09-27
E. R. Squibb & Sons, Inc.
Use of enkephalinase inhibitors as analgesic agents
US4801609B1
(en)
*
1987-03-27
1993-11-09
Mercapto-acylamino acid antihypertensives
US4740499A
(en)
*
1986-07-28
1988-04-26
Monsanto Company
Method of enhancing the bioactivity of atrial peptides
KR880007441A
(en)
*
1986-12-11
1988-08-27
알렌 제이.스피겔
Spiro-Substituted Glutaramide Diuretics
CA1337400C
(en)
*
1987-06-08
1995-10-24
Norma G. Delaney
Inhibitors of neutral endopeptidase
1990
1990-03-09
US
US07/491,148
patent/US5075302A/en
not_active
Expired – Fee Related
1991
1991-03-07
AU
AU74566/91A
patent/AU7456691A/en
not_active
Abandoned
1991-03-07
EP
EP91905618A
patent/EP0518943A1/en
not_active
Withdrawn
1991-03-07
CA
CA002077746A
patent/CA2077746A1/en
not_active
Abandoned
1991-03-07
WO
PCT/US1991/001420
patent/WO1991013870A1/en
not_active
Application Discontinuation
1991-03-07
JP
JP3505469A
patent/JPH0688969B2/en
not_active
Expired – Lifetime
Also Published As
Publication number
Publication date
WO1991013870A1
(en)
1991-09-19
EP0518943A1
(en)
1992-12-23
JPH0688969B2
(en)
1994-11-09
CA2077746A1
(en)
1991-09-10
US5075302A
(en)
1991-12-24
JPH05504772A
(en)
1993-07-22
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