GB1046435A – Improvements in or relating to podophyllum glucosides
– Google Patents
GB1046435A – Improvements in or relating to podophyllum glucosides
– Google Patents
Improvements in or relating to podophyllum glucosides
Info
Publication number
GB1046435A
GB1046435A
GB18780/63A
GB1878063A
GB1046435A
GB 1046435 A
GB1046435 A
GB 1046435A
GB 18780/63 A
GB18780/63 A
GB 18780/63A
GB 1878063 A
GB1878063 A
GB 1878063A
GB 1046435 A
GB1046435 A
GB 1046435A
Authority
GB
United Kingdom
Prior art keywords
glucoside
benzylidene
podophyllum
mixture
optionally
Prior art date
1962-05-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18780/63A
Inventor
Jany Renz
Albert Von Wartburg
Emil Angliker
Hans Emmenegger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Sandoz AG
Original Assignee
Sandoz Patent Ltd
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1962-05-24
Filing date
1963-05-13
Publication date
1966-10-26
1963-05-13
Application filed by Sandoz Patent Ltd, Sandoz AG
filed
Critical
Sandoz Patent Ltd
1966-10-26
Publication of GB1046435A
publication
Critical
patent/GB1046435A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K36/18—Magnoliophyta (angiosperms)
A61K36/185—Magnoliopsida (dicotyledons)
A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
Abstract
A novel reaction product resulting from extracting dried podophyllum rhizomes with a water miscible aliphatic alcohol, optionally treating with a tannin precipitating agent, optionally additionally extracting the material into an alcohol/chlorinated hydrocarbon mixture, and directly condensing with benzaldehyde the glucoside mixture contained in the said extract after removal of non-glucosidal components, preferably by prior extraction of these with a chlorinated hydrocarbon.ALSO:Pharmaceutical compositions comprise an inert diluent and a novel reaction product resulting from extracting dried podophyllum rhizomes with a water miscible aliphatic alcohol and directly condensing with benzaldehyde the glucoside mixture contained in the said extract after removal of non-glucosidal components. The examples contain a mixture of podophyllotoxin-benzylidene-b -D-glucoside, 41-demethyl-podophyllotoxin-benzylidene-b -D-glucoside, an aglucone and resin fraction, unreacted glucosides and additional unidentified matter optionally with a – and b -peltatin-benzylidene-b -D-glucoside being present.
GB18780/63A
1962-05-24
1963-05-13
Improvements in or relating to podophyllum glucosides
Expired
GB1046435A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
CH629562A
CH420197A
(en)
1962-05-24
1962-05-24
Process for the production of a new mitosis-inhibiting preparation
Publications (1)
Publication Number
Publication Date
GB1046435A
true
GB1046435A
(en)
1966-10-26
Family
ID=4307300
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB18780/63A
Expired
GB1046435A
(en)
1962-05-24
1963-05-13
Improvements in or relating to podophyllum glucosides
Country Status (13)
Country
Link
AT
(1)
AT256335B
(en)
BR
(1)
BR6349355D0
(en)
CH
(1)
CH420197A
(en)
DE
(1)
DE1518141C3
(en)
DK
(1)
DK107437C
(en)
ES
(1)
ES288250A1
(en)
FI
(1)
FI46030C
(en)
GB
(1)
GB1046435A
(en)
LU
(1)
LU43801A1
(en)
MY
(1)
MY6900115A
(en)
NL
(1)
NL144153B
(en)
OA
(1)
OA00708A
(en)
SE
(1)
SE318973B
(en)
1962
1962-05-24
CH
CH629562A
patent/CH420197A/en
unknown
1963
1963-05-13
GB
GB18780/63A
patent/GB1046435A/en
not_active
Expired
1963-05-17
NL
NL63292903A
patent/NL144153B/en
unknown
1963-05-22
DE
DE1518141A
patent/DE1518141C3/en
not_active
Expired
1963-05-22
SE
SE5742/63A
patent/SE318973B/xx
unknown
1963-05-22
LU
LU43801D
patent/LU43801A1/xx
unknown
1963-05-22
FI
FI631057A
patent/FI46030C/en
active
1963-05-22
ES
ES288250A
patent/ES288250A1/en
not_active
Expired
1963-05-22
DK
DK244063AA
patent/DK107437C/en
active
1963-05-22
AT
AT413763A
patent/AT256335B/en
active
1963-05-24
BR
BR149355/63A
patent/BR6349355D0/en
unknown
1964
1964-12-08
OA
OA50788A
patent/OA00708A/en
unknown
1969
1969-12-31
MY
MY1969115A
patent/MY6900115A/en
unknown
Also Published As
Publication number
Publication date
ES288250A1
(en)
1963-12-01
DK107437C
(en)
1967-05-29
DE1518141A1
(en)
1969-07-24
AT256335B
(en)
1967-08-10
OA00708A
(en)
1967-07-15
SE318973B
(en)
1969-12-22
NL144153B
(en)
1974-12-16
MY6900115A
(en)
1969-12-31
CH420197A
(en)
1966-09-15
FI46030C
(en)
1972-12-11
FI46030B
(en)
1972-08-31
DE1518141C3
(en)
1973-09-27
DE1518141B2
(en)
1973-03-08
LU43801A1
(en)
1963-10-22
BR6349355D0
(en)
1973-08-02
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