GB1046543A - Creation of Inventions and Patents with Artificial Intelligence

GB1046543A – Improvements in or relating to azathiaxanthene derivatives
– Google Patents

GB1046543A – Improvements in or relating to azathiaxanthene derivatives
– Google Patents
Improvements in or relating to azathiaxanthene derivatives

Info

Publication number
GB1046543A

GB1046543A
GB4109/64A
GB410964A
GB1046543A
GB 1046543 A
GB1046543 A
GB 1046543A
GB 4109/64 A
GB4109/64 A
GB 4109/64A
GB 410964 A
GB410964 A
GB 410964A
GB 1046543 A
GB1046543 A
GB 1046543A
Authority
GB
United Kingdom
Prior art keywords
aza
halo
general formula
acid
signifies
Prior art date
1963-02-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB4109/64A
Inventor
Ernst Jucker
Anton Ebnoether
Erwin Rissi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz Patent Ltd

Sandoz AG

Original Assignee
Sandoz Patent Ltd
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1963-02-22
Filing date
1964-01-31
Publication date
1966-10-26

1963-02-22
Priority claimed from CH224663A
external-priority
patent/CH420165A/en

1964-01-31
Application filed by Sandoz Patent Ltd, Sandoz AG
filed
Critical
Sandoz Patent Ltd

1966-10-26
Publication of GB1046543A
publication
Critical
patent/GB1046543A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

C07D495/04—Ortho-condensed systems

Abstract

The invention comprises compounds of the general formula wherein R1 signifies hydrogen or an alkyl radical containing from 1-4 carbon atoms, R2 signifies a hydrogen or halogen atom and R3 signifies an alkyl radical containing from 1-4 carbon atoms, and their acid addition salts, and the preparation thereof by oxidizing a compound of general formula with hydrogen peroxide, an organic peracid, an inorganic peracid or salts thereof, especially with an alkali metal metaperiodate for 4-5 days at room temperature. The acid addition salts may be prepared by addition of an organic or inorganic acid to the above compounds. Pharmaceutical compositions comprise a compound of the first general formula above and an inert diluent for enteral or parentaral administration. The therapeutic compositions are anti-histaminics, antiallergics, narcosis potentiators and adrenolytics. 7 – Halo – 9 – (11 – alkylpiperidylidene – 41) – 4 – aza – thiaxanthenes of the second general formula above (R2 = halogen) are prepared by reacting a 7-halo-4-aza-thiaxanthone with a 1-alkyl-4-piperidyl magnesium halide, hydrolysing the Grignard complex and treating the resulting 7 – halo – 9 – (11 – alkylpiperidyl – 41) – aza-thiaxanthydrol with a dehydrating agent. 7-Halo-4-aza-thiaxanthones are prepared by condensing a 2-chloronicotinic acid with a p-halothiophenol and cyclizing the resulting 3-carboxypyridyl-(2) p-halophenyl sulphide by heating with polyphosphoric acid.

GB4109/64A
1963-02-22
1964-01-31
Improvements in or relating to azathiaxanthene derivatives

Expired

GB1046543A
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

CH224663A

CH420165A
(en)

1963-02-22
1963-02-22

Process for the preparation of new heterocyclic compounds

CH432163

1963-04-04

Publications (1)

Publication Number
Publication Date

GB1046543A
true

GB1046543A
(en)

1966-10-26

Family
ID=25689891
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB4109/64A
Expired

GB1046543A
(en)

1963-02-22
1964-01-31
Improvements in or relating to azathiaxanthene derivatives

Country Status (6)

Country
Link

AT
(1)

AT240376B
(en)

BE
(1)

BE644121A
(en)

DK
(1)

DK103831C
(en)

ES
(1)

ES296634A1
(en)

FR
(1)

FR3403M
(en)

GB
(1)

GB1046543A
(en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

IE68935B1
(en)

1990-06-22
1996-07-24
Schering Corp
Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use

EP0586560A1
(en)

1991-05-23
1994-03-16
Schering Corporation
Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use

AU2392392A
(en)

1991-07-23
1993-02-23
Schering Corporation
Novel benzopyrido piperylidene compounds, compositions, methods of manufacture and methods of use

WO1993020080A1
(en)

1992-03-27
1993-10-14
Schering Corporation
Bridged bis-aryl carbinol derivatives, compositions and methods of use

AU3918993A
(en)

1992-03-27
1993-11-08
Schering Corporation
Unbridged bis-aryl carbinol derivatives, compositions and methods of use

1964

1964-01-31
GB
GB4109/64A
patent/GB1046543A/en
not_active
Expired

1964-02-20
ES
ES296634A
patent/ES296634A1/en
not_active
Expired

1964-02-20
AT
AT143264A
patent/AT240376B/en
active

1964-02-20
BE
BE644121A
patent/BE644121A/xx
unknown

1964-02-21
DK
DK86664A
patent/DK103831C/en
active

1964-05-19
FR
FR975012A
patent/FR3403M/en
not_active
Expired

Also Published As

Publication number
Publication date

FR3403M
(en)

1965-06-28

BE644121A
(en)

1964-08-20

ES296634A1
(en)

1964-09-01

AT240376B
(en)

1965-05-25

DK103831C
(en)

1966-02-28

Contact information