GB1065296A - Creation of Inventions and Patents with Artificial Intelligence

GB1065296A – Phenthiazine derivatives
– Google Patents

GB1065296A – Phenthiazine derivatives
– Google Patents
Phenthiazine derivatives

Info

Publication number
GB1065296A

GB1065296A
GB6688/65A
GB668865A
GB1065296A
GB 1065296 A
GB1065296 A
GB 1065296A
GB 6688/65 A
GB6688/65 A
GB 6688/65A
GB 668865 A
GB668865 A
GB 668865A
GB 1065296 A
GB1065296 A
GB 1065296A
Authority
GB
United Kingdom
Prior art keywords
formula
imidazolidone
ethyl
methyl
carbethoxypiperazine
Prior art date
1964-02-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB6688/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ASTA-WERKE AG

Asta Medica GmbH

Original Assignee
ASTA-WERKE AG
Asta Werke AG Chemische Fabrik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1964-02-28
Filing date
1965-02-16
Publication date
1967-04-12

1965-02-16
Application filed by ASTA-WERKE AG, Asta Werke AG Chemische Fabrik
filed
Critical
ASTA-WERKE AG

1967-04-12
Publication of GB1065296A
publication
Critical
patent/GB1065296A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

WJFKNYWRSNBZNX-UHFFFAOYSA-N
10H-phenothiazine
Chemical class

C1=CC=C2NC3=CC=CC=C3SC2=C1
WJFKNYWRSNBZNX-UHFFFAOYSA-N
0.000
title
abstract
2

239000002253
acid
Substances

0.000
abstract
3

YAMHXTCMCPHKLN-UHFFFAOYSA-N
imidazolidin-2-one
Chemical compound

O=C1NCCN1
YAMHXTCMCPHKLN-UHFFFAOYSA-N
0.000
abstract
3

150000007513
acids
Chemical class

0.000
abstract
2

150000001875
compounds
Chemical class

0.000
abstract
2

125000001495
ethyl group
Chemical group

[H]C([H])([H])C([H])([H])*

0.000
abstract
2

LNOQURRKNJKKBU-UHFFFAOYSA-N
ethyl piperazine-1-carboxylate
Chemical compound

CCOC(=O)N1CCNCC1
LNOQURRKNJKKBU-UHFFFAOYSA-N
0.000
abstract
2

125000002496
methyl group
Chemical group

[H]C([H])([H])*

0.000
abstract
2

229950000688
phenothiazine
Drugs

0.000
abstract
2

-1
phenothiazine compound
Chemical class

0.000
abstract
2

150000003839
salts
Chemical class

0.000
abstract
2

DPUVPRWTWNQSOS-UHFFFAOYSA-N
3-chloro-10h-phenothiazine
Chemical compound

C1=CC=C2SC3=CC(Cl)=CC=C3NC2=C1
DPUVPRWTWNQSOS-UHFFFAOYSA-N
0.000
abstract
1

239000011230
binding agent
Substances

0.000
abstract
1

230000000911
decarboxylating effect
Effects

0.000
abstract
1

239000003085
diluting agent
Substances

0.000
abstract
1

230000000694
effects
Effects

0.000
abstract
1

150000002148
esters
Chemical class

0.000
abstract
1

239000000203
mixture
Substances

0.000
abstract
1

238000007911
parenteral administration
Methods

0.000
abstract
1

239000008194
pharmaceutical composition
Substances

0.000
abstract
1

150000004885
piperazines
Chemical class

0.000
abstract
1

125000001436
propyl group
Chemical group

[H]C([*])([H])C([H])([H])C([H])([H])[H]

0.000
abstract
1

SQMCFUSVGSBKFK-UHFFFAOYSA-N
sodium;5-(cyclohexen-1-yl)-1,5-dimethyl-1,3-diazinane-2,4,6-trione
Chemical compound

[Na+].O=C1N(C)C(=O)NC(=O)C1(C)C1=CCCCC1
SQMCFUSVGSBKFK-UHFFFAOYSA-N
0.000
abstract
1

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00

C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings

C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00

C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

Compounds of the general formula and their salts with pharmacologically acceptable acids, where R is methyl or ethyl and n is 2 or 3 are prepared by reacting (a) a phenothiazine of the formula where X is the residue of a reactive ester with an imidazolidone of the formula or (b) 3-chlorophenothiazine with an imidazolidone of the formula at an elevated temperature; or (c) a phenothiazine compound of the formula with an imidazolidone derivative of the formula at an elevated temperature and in the presence of an acid binding agent. N – [b – (1 – Methyl and 1 – ethyl – 2 – oxoimidazolidyl)-ethyl and propyl] piperazines are prepared by reacting the 1-alkyl-3-b -chloroethyl – imidazolidone – (2) with mono carbethoxypiperazine and decarboxylating the N-carbethoxypiperazine derivative formed.ALSO:Pharmaceutical compositions comprise compounds of the formula or their salts with pharmacologically acceptable acids, wherein n is 2 or 3 and R is methyl or ethyl, and an inert carrier or diluent. Examples are given of parenteral administration of the compositions and of the naicosis prolonging effect on previously administered hexobarbital -Na.

GB6688/65A
1964-02-28
1965-02-16
Phenthiazine derivatives

Expired

GB1065296A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

DEA45348A

DE1243199B
(en)

1964-02-28
1964-02-28

Process for the production of new phenthiazine derivatives

Publications (1)

Publication Number
Publication Date

GB1065296A
true

GB1065296A
(en)

1967-04-12

Family
ID=6934670
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB6688/65A
Expired

GB1065296A
(en)

1964-02-28
1965-02-16
Phenthiazine derivatives

Country Status (8)

Country
Link

US
(1)

US3320247A
(en)

BE
(1)

BE668972A
(en)

BG
(1)

BG15398A3
(en)

CH
(1)

CH446340A
(en)

DE
(1)

DE1243199B
(en)

FR
(1)

FR4223M
(en)

GB
(1)

GB1065296A
(en)

MY
(1)

MY6900349A
(en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

BE666965A
(en)

1964-07-17

BE754642A
(en)

1969-08-11
1971-02-10
Geigy Ag J R

IMIDAZOLIDINONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES

BE754641A
(en)

1969-08-11
1971-02-10
Geigy Ag J R

IMIDAZOLIDINONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES

BE754640A
(en)

1969-08-11
1971-02-10
Geigy Ag J R

IMIDAZOLIDINONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES

CN106143066A
(en)

2016-08-09
2016-11-23
上海贝洱热系统有限公司
Scalable perfume (or spice) atmosphere vaporizer

CN107310350A
(en)

2017-06-27
2017-11-03
大陆汽车投资（上海）有限公司
Vehicle air adjusting means

CN115381995A
(en)

2018-01-18
2022-11-25
宝洁公司
Method of delivering volatile compositions into the air

Family Cites Families (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE1097995B
(en)

1956-03-08
1961-01-26
Egyt Gyogyszervegyeszeti Gyar

Process for the preparation of phenthiazine derivatives

1964

1964-02-28
DE
DEA45348A
patent/DE1243199B/en
active
Pending

1965

1965-02-10
US
US431712A
patent/US3320247A/en
not_active
Expired – Lifetime

1965-02-12
CH
CH191465A
patent/CH446340A/en
unknown

1965-02-16
GB
GB6688/65A
patent/GB1065296A/en
not_active
Expired

1965-02-27
FR
FR7353A
patent/FR4223M/fr
not_active
Expired

1965-08-31
BE
BE668972D
patent/BE668972A/xx
unknown

1967

1967-06-27
BG
BG015398A
patent/BG15398A3/en
unknown

1969

1969-12-31
MY
MY1969349A
patent/MY6900349A/en
unknown

Also Published As

Publication number
Publication date

BG15398A3
(en)

1976-05-26

US3320247A
(en)

1967-05-16

BE668972A
(en)

1965-12-16

MY6900349A
(en)

1969-12-31

DE1243199B
(en)

1967-06-29

FR4223M
(en)

1966-06-13

CH446340A
(en)

1967-11-15

Contact information