GB1107935A – A 7-chloro-4-aminoalkylaminoquinoline, its preparation and pharmaceutical compositions
– Google Patents
GB1107935A – A 7-chloro-4-aminoalkylaminoquinoline, its preparation and pharmaceutical compositions
– Google Patents
A 7-chloro-4-aminoalkylaminoquinoline, its preparation and pharmaceutical compositions
Info
Publication number
GB1107935A
GB1107935A
GB20524/66A
GB2052466A
GB1107935A
GB 1107935 A
GB1107935 A
GB 1107935A
GB 20524/66 A
GB20524/66 A
GB 20524/66A
GB 2052466 A
GB2052466 A
GB 2052466A
GB 1107935 A
GB1107935 A
GB 1107935A
Authority
GB
United Kingdom
Prior art keywords
chloro
quinoline
acid
methylbutylamino
hydroxyethylamino
Prior art date
1965-05-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20524/66A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1965-05-18
Filing date
1966-05-09
Publication date
1968-03-27
1966-05-09
Application filed by Sterling Drug Inc
filed
Critical
Sterling Drug Inc
1968-03-27
Publication of GB1107935A
publication
Critical
patent/GB1107935A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D215/38—Nitrogen atoms
C07D215/42—Nitrogen atoms attached in position 4
C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
Abstract
7 – Chloro – 4 – [4 – (2 – hydroxyethylamino) – 1 – methylbutylamino] quinoline or an acid addition salt thereof is made by reacting a 7 – chloro – 4 – (4 – halo – 1 – methylbutylamino)-quinoline with 2-hydroxyethylamine and, if desired, reacting the free base obtained with an acid to form a salt. Specified salts include those of oxalic, pamoic, phosphoric, sulphuric, methanesulphonic, 3 – hydroxy – 2 – naphthoic, naponic, salicylic, mucic and muconic acids.ALSO:Anti-inflammatory compositions comprise 7 – chloro – 4 – [4 – (2 – hydroxyethylamino) – 1-methyl-butylamino] quinoline or an acid addition salt thereof and a pharmaceutical carrier. Optional additional ingredients are the corticosteroids, e.g. prednisone, prednisolone, cortisone, hydrocortisone and the 9- or 12-halocorticosteroids; or non-steroids, e.g. acetylsalicylic acid, salicylamide, aminopyrine, chloroquine and hydroxychloroquine. The compositions may be formulated in dosage units for oral or parenteral administration.
GB20524/66A
1965-05-18
1966-05-09
A 7-chloro-4-aminoalkylaminoquinoline, its preparation and pharmaceutical compositions
Expired
GB1107935A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US456810A
US3415932A
(en)
1965-05-18
1965-05-18
7 – chloro – 4 – [4-(2-hydroxyethylamino)-1-methylbutylamino]quinoline; anti-inflammatory compositions and method using same
Publications (1)
Publication Number
Publication Date
GB1107935A
true
GB1107935A
(en)
1968-03-27
Family
ID=23814240
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB20524/66A
Expired
GB1107935A
(en)
1965-05-18
1966-05-09
A 7-chloro-4-aminoalkylaminoquinoline, its preparation and pharmaceutical compositions
Country Status (11)
Country
Link
US
(1)
US3415932A
(en)
AT
(1)
AT265272B
(en)
BE
(1)
BE681170A
(en)
BR
(1)
BR6679514D0
(en)
CH
(1)
CH471785A
(en)
DE
(1)
DE1620489A1
(en)
FR
(1)
FR5494M
(en)
GB
(1)
GB1107935A
(en)
MY
(1)
MY7000048A
(en)
NL
(1)
NL6606704A
(en)
NO
(1)
NO118153B
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
RU2580656C1
(en)
*
2014-11-20
2016-04-10
Закрытое Акционерное Общество “БИОКОМ”
Immediate-release solid dosage form of hydroxychloroquine and method for producing it
Families Citing this family (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP2967062A4
(en)
2013-03-15
2016-10-19
Univ Leland Stanford Junior
Desethylhydroxychloroquine for the treatment of diseases associated with inflammation
Family Cites Families (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US2546658A
(en)
*
1949-07-23
1951-03-27
Sterling Drug Inc
7-chloro-4-[5-(n-ethyl-n-2-hydroxyethylamino)-2-pentyl] aminoquinoline, its acid addition salts, and method of preparation
1965
1965-05-18
US
US456810A
patent/US3415932A/en
not_active
Expired – Lifetime
1966
1966-05-09
GB
GB20524/66A
patent/GB1107935A/en
not_active
Expired
1966-05-16
NL
NL6606704A
patent/NL6606704A/xx
unknown
1966-05-16
FR
FR61701A
patent/FR5494M/fr
not_active
Expired
1966-05-16
NO
NO163035A
patent/NO118153B/no
unknown
1966-05-17
AT
AT466466A
patent/AT265272B/en
active
1966-05-17
BE
BE681170D
patent/BE681170A/xx
unknown
1966-05-17
BR
BR179514/66A
patent/BR6679514D0/en
unknown
1966-05-17
CH
CH714066A
patent/CH471785A/en
not_active
IP Right Cessation
1966-05-18
DE
DE19661620489
patent/DE1620489A1/en
active
Pending
1970
1970-12-31
MY
MY197048A
patent/MY7000048A/en
unknown
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
RU2580656C1
(en)
*
2014-11-20
2016-04-10
Закрытое Акционерное Общество “БИОКОМ”
Immediate-release solid dosage form of hydroxychloroquine and method for producing it
Also Published As
Publication number
Publication date
CH471785A
(en)
1969-04-30
NO118153B
(en)
1969-11-17
FR5494M
(en)
1967-10-30
MY7000048A
(en)
1970-12-31
AT265272B
(en)
1968-10-10
BR6679514D0
(en)
1973-10-23
DE1620489A1
(en)
1970-04-30
NL6606704A
(en)
1966-11-21
US3415932A
(en)
1968-12-10
BE681170A
(en)
1966-11-17
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None