GB1135966A - Creation of Inventions and Patents with Artificial Intelligence

GB1135966A – Improvements in or relating to sustained-release medicaments
– Google Patents

GB1135966A – Improvements in or relating to sustained-release medicaments
– Google Patents
Improvements in or relating to sustained-release medicaments

Info

Publication number
GB1135966A

GB1135966A
GB832/67A
GB83267A
GB1135966A
GB 1135966 A
GB1135966 A
GB 1135966A
GB 832/67 A
GB832/67 A
GB 832/67A
GB 83267 A
GB83267 A
GB 83267A
GB 1135966 A
GB1135966 A
GB 1135966A
Authority
GB
United Kingdom
Prior art keywords
jan
medicament
ethylene glycol
sustained
hydrogel
Prior art date
1966-01-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB832/67A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Czech Academy of Sciences CAS

Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1966-01-06
Filing date
1967-01-06
Publication date
1968-12-11

1967-01-06
Application filed by Czech Academy of Sciences CAS
filed
Critical
Czech Academy of Sciences CAS

1968-12-11
Publication of GB1135966A
publication
Critical
patent/GB1135966A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/20—Pills, tablets, discs, rods

A61K9/2004—Excipients; Inactive ingredients

A61K9/2022—Organic macromolecular compounds

A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

C—CHEMISTRY; METALLURGY

C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON

C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS

C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds

C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds

C08F36/20—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds unconjugated

Abstract

1,135,966. Sustained-release medicaments. CESKOSLOVENSKA AKADEMIE VED. 6 Jan., 1967 [6 Jan., 1966; 9 Jan., 1966], No. 832/67. Headings A5B and A5R. Pharmaceutical preparations for the sustained administration of a medicament to a living organism in direct contact therewith comprise a hydrogel of a polymer which is insoluble but swellable in the fluids of the living organism and which is prepared by copolymerising a hydrophilic mono-olefinic monomer with 0.1 to 5% of a cross-linking agent which surrounds, or in which is incorporated, a soluble biologically active substance which is diffusible through the hydrogel. Forms of preparation mentioned include inplants, prostheses, granules, and delayed release forms (in which the polymer may be an ionexchanger which binds the medicament). Suitable polymers are those derived from such monomers as ethylene glycol monomethacrylate, ethylene glycol monoacrylate, their polyethylene glycol and poly-ethylene glycol/ propylene glycol analogues, methacrylamide, acrylamide, maleic acid anhydride, methacrylic acid, acrylic acid, alkali metal ethylene sulphonate and mixtures thereof. Numerous types of medicament are mentioned, specific examples relating to preparations comprising chloramphenical (microporous sponge for treating burns). 1-γ-oxabutyl-2,5-dioxo-3,4-diphenyl pyrazolidine (implant tablets), tetracycline hydrochloride (sponge), hormones e.g. dihydrocortisone and ovarial or androgenic hormones and 6-azauridine (films) and oxytetracycline (implant).

GB832/67A
1966-01-06
1967-01-06
Improvements in or relating to sustained-release medicaments

Expired

GB1135966A
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

CS8366

1966-01-06

CS83866

1966-02-09

Publications (1)

Publication Number
Publication Date

GB1135966A
true

GB1135966A
(en)

1968-12-11

Family
ID=25745236
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB832/67A
Expired

GB1135966A
(en)

1966-01-06
1967-01-06
Improvements in or relating to sustained-release medicaments

Country Status (7)

Country
Link

US
(2)

US3551556A
(en)

AU
(1)

AU411053B2
(en)

DE
(1)

DE1617393C2
(en)

ES
(1)

ES335314A1
(en)

FR
(1)

FR1586811A
(en)

GB
(1)

GB1135966A
(en)

IT
(1)

IT1050353B
(en)

Cited By (10)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2052973A1
(en)

1969-06-16
1971-04-16
Reese Hospital Michael

FR2187290A1
(en)

1972-06-09
1974-01-18
Purdue Research Foundation

FR2355510A1
(en)

1976-06-21
1978-01-20
Toko Yakuhin Kogyo Kk

PROCESS FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF AQUEOUS SOLUTION OF CARBOXYVINYL POLYMER WITH A BASIC COMPOUND

US4202880A
(en)

1976-12-13
1980-05-13
Imperial Chemical Industries Limited
Delivery means for biologically active agents comprising hydrophilic polyurethane

US4235988A
(en)

1976-12-13
1980-11-25
Imperial Chemical Industries Limited
Delivery means for biologically active agents

US4296097A
(en)

1979-02-27
1981-10-20
Lee Weng Y
Suppression of reaginic antibodies to drugs employing polyvinyl alcohol as carrier therefor

US4430260A
(en)

1979-02-27
1984-02-07
Lee Weng Y
Penicillin-polyvinyl alcohol conjugate and process of preparation

GB2181053A
(en)

1985-10-01
1987-04-15
Sandoz Ltd
Controlled release formulation

US4894238A
(en)

1979-03-21
1990-01-16
National Research Development Corporation
Controlled release compositions

US5342624A
(en)

1989-02-16
1994-08-30
British Technology Group Ltd.
Dispensing device

Families Citing this family (105)

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Publication number
Priority date
Publication date
Assignee
Title

DE1617393C2
(en)

1966-01-06
1982-11-11
Československá akademie věd, Praha

Process for the preparation of hydrophilic crosslinked copolymers containing biologically active substances

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(en)

1968-03-06
1975-05-20
Ceskoslovenska Akademie Ved
Hydrogel laminates and method of manufacturing thereof

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1968-04-22
1975-01-14
Searle & Co
Method for use and compositions of 11-lower alkyl steroids and drug delivery system for the controlled elution of 11-lower alkyl steroids

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1970-09-09
1974-12-31
F Gould
Dry hydrophilic acrylate or methacrylate polymer prolonged release drug implants

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1970-09-29
1973-01-16
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Drug-delivery device with stretched, rate-controlling membrane

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1971-01-08
1974-09-16

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1971-06-04
1973-05-08
Alza Corp
Bandage for the controlled metering of topical drugs to the skin

BE789524A
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1971-09-30
1973-01-15
Alza Corp

DRUG RELEASE SYSTEM

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1972-12-27
1974-05-21
Alza Corp
Bioerodible ocular device

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1973-03-28
1976-05-04
A/S Alfred Benzon
Oral drug preparations

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1973-05-04
1975-11-18
Merck & Co Inc
Growth promoting subcutaneous compositions

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1973-09-10
1975-09-09
Union Corp
Sustained release of chlorpheniramine maleate

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1973-09-10
1975-10-07
Union Corp
Sustained release of methantheline

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1973-09-10
1975-08-26
Union Corp
Sustained release of methantheline

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1973-09-10
1975-08-26
Union Corp
Sustained release of methantheline

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1973-09-10
1979-12-11
Union Corporation
Sustained release pharmaceutical composition

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1973-09-10
1975-08-26
Union Corp
Sustained release of atropine

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1973-09-10
1977-02-08
Union Corporation
Sustained release pesticidal composition

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1973-09-10
1975-08-26
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1973-09-10
1975-08-26
Union Corp
Sustained release of hydrochlorothiazide

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1973-09-10
1975-08-26
Union Corp
Sustained release of dexamethasone

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1973-10-26
1975-08-26
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1975-12-29
1980-07-30
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1976-01-05
1980-01-29
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1981-01-13
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1978-05-03
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1977-07-20
1979-01-23
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1978-03-03
1981-07-07
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1978-10-20
1980-07-01
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1979-09-10
1981-11-03
National Patent Development Corporation
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1979-12-05
1986-11-17
Medline Ab

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1982-06-21
1984-04-17
Euroceltique, S.A.
Extended action controlled release compositions

GB8305797D0
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1983-03-02
1983-04-07
Graham N B
Hydrogel-containing envelopes

CA1196863A
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1983-06-08
1985-11-19
Mattheus F.A. Goosen
Slow release injectable insulin composition

GB8331546D0
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1983-11-25
1984-01-04
Exxon Research Engineering Co
Polymeric compositions

US4749576A
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1984-05-10
1988-06-07
Ciba-Geigy Corporation
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US4624848A
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1984-05-10
1986-11-25
Ciba-Geigy Corporation
Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use

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1985-05-20
1987-06-16
Autotrol Corporation
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Sustained-release formulation containing and amino acid polymer

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1987-06-04
Sunstar Inc
Ointment base

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1990-08-14
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1988-10-20
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Biocompatible implants.

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1986-05-22
1990-09-25
Syntex (U.S.A.) Inc.
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1989-08-08
Dow Corning Corporation
Lattice-entrapped composition

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American Cyanamid Company
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1994-01-11
Fmc Corporation
Gel-in-matrix containing a fractured hydrogel

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1987-11-25
1990-06-05
Minnesota Mining And Manufacturing Company
Pressure-sensitive medical sealant

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1991-09-10
Watson Laboratories, Inc.
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1995-03-30
Columbia Lab Inc

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US6764697B1
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Family Cites Families (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3220960A
(en)

1960-12-21
1965-11-30
Wichterle Otto
Cross-linked hydrophilic polymers and articles made therefrom

DE1617393C2
(en)

1966-01-06
1982-11-11
Československá akademie věd, Praha

Process for the preparation of hydrophilic crosslinked copolymers containing biologically active substances

1967

1967-01-05
DE
DE1617393A
patent/DE1617393C2/en
not_active
Expired

1967-01-05
FR
FR1586811D
patent/FR1586811A/fr
not_active
Expired

1967-01-05
IT
IT11212/67A
patent/IT1050353B/en
active

1967-01-05
ES
ES0335314A
patent/ES335314A1/en
not_active
Expired

1967-01-06
AU
AU16202/67A
patent/AU411053B2/en
not_active
Expired

1967-01-06
GB
GB832/67A
patent/GB1135966A/en
not_active
Expired

1967-01-06
US
US607637A
patent/US3551556A/en
not_active
Expired – Lifetime

1970

1970-09-23
US
US74905A
patent/US3689634A/en
not_active
Expired – Lifetime

Cited By (12)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2052973A1
(en)

1969-06-16
1971-04-16
Reese Hospital Michael

FR2187290A1
(en)

1972-06-09
1974-01-18
Purdue Research Foundation

FR2355510A1
(en)

1976-06-21
1978-01-20
Toko Yakuhin Kogyo Kk

PROCESS FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF AQUEOUS SOLUTION OF CARBOXYVINYL POLYMER WITH A BASIC COMPOUND

US4202880A
(en)

1976-12-13
1980-05-13
Imperial Chemical Industries Limited
Delivery means for biologically active agents comprising hydrophilic polyurethane

US4235988A
(en)

1976-12-13
1980-11-25
Imperial Chemical Industries Limited
Delivery means for biologically active agents

US4296097A
(en)

1979-02-27
1981-10-20
Lee Weng Y
Suppression of reaginic antibodies to drugs employing polyvinyl alcohol as carrier therefor

US4430260A
(en)

1979-02-27
1984-02-07
Lee Weng Y
Penicillin-polyvinyl alcohol conjugate and process of preparation

US4894238A
(en)

1979-03-21
1990-01-16
National Research Development Corporation
Controlled release compositions

US4931288A
(en)

1979-03-21
1990-06-05
Lloyds Bank Plc
Controlled release compositions (II)

GB2181053A
(en)

1985-10-01
1987-04-15
Sandoz Ltd
Controlled release formulation

GB2181053B
(en)

1985-10-01
1990-05-23
Sandoz Ltd
Pharmaceutical formulations with controlled release of the active substance

US5342624A
(en)

1989-02-16
1994-08-30
British Technology Group Ltd.
Dispensing device

Also Published As

Publication number
Publication date

US3689634A
(en)

1972-09-05

AU1620267A
(en)

1968-07-11

FR1586811A
(en)

1970-03-06

IT1050353B
(en)

1981-03-10

ES335314A1
(en)

1967-12-01

US3551556A
(en)

1970-12-29

DE1617393A1
(en)

1971-03-18

AU411053B2
(en)

1971-03-01

DE1617393C2
(en)

1982-11-11

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