GB1205751A

GB1205751A – Improvements relating to multiple pipetting apparatus
– Google Patents

GB1205751A – Improvements relating to multiple pipetting apparatus
– Google Patents
Improvements relating to multiple pipetting apparatus

Info

Publication number
GB1205751A

GB1205751A
GB33226/66A
GB3322666A
GB1205751A
GB 1205751 A
GB1205751 A
GB 1205751A
GB 33226/66 A
GB33226/66 A
GB 33226/66A
GB 3322666 A
GB3322666 A
GB 3322666A
GB 1205751 A
GB1205751 A
GB 1205751A
Authority
GB
United Kingdom
Prior art keywords
bar
motor
nozzle
frame
syringes
Prior art date
1966-07-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB33226/66A
Inventor
Peter James Littlejoh Sequeira
Alan Rendal Drake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Baird and Tatlock Ltd

Original Assignee
Baird and Tatlock Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1966-07-23
Filing date
1966-07-23
Publication date
1970-09-16

1966-07-23
Application filed by Baird and Tatlock Ltd
filed
Critical
Baird and Tatlock Ltd

1966-07-23
Priority to GB33226/66A
priority
Critical
patent/GB1205751A/en

1967-07-21
Priority to SE10770/67*A
priority
patent/SE357620B/xx

1967-07-24
Priority to DE1648818A
priority
patent/DE1648818B2/en

1969-11-03
Priority to US871609A
priority
patent/US3551112A/en

1970-09-16
Publication of GB1205751A
publication
Critical
patent/GB1205751A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

239000007788
liquid
Substances

0.000
abstract
4

230000000284
resting effect
Effects

0.000
abstract
2

230000001154
acute effect
Effects

0.000
abstract
1

230000015572
biosynthetic process
Effects

0.000
abstract
1

239000003153
chemical reaction reagent
Substances

0.000
abstract
1

230000003993
interaction
Effects

0.000
abstract
1

XLYOFNOQVPJJNP-UHFFFAOYSA-N
water
Substances

O
XLYOFNOQVPJJNP-UHFFFAOYSA-N
0.000
abstract
1

Classifications

G—PHYSICS

G01—MEASURING; TESTING

G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor

G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes

Abstract

1,205,751. Multiple pipetting apparatus. BAIRD & TATLOCK (LONDON) Ltd. 24 July, 1967 [23 July, 1966], No. 33226/66. Heading B1X. Multiple pipetting apparatus comprises a carriage 2, Fig. 14 for supporting in a generally rectangular array a plurality of receptacles, a positioning mechanism 3, Fig. 2, comprising a nozzle support 4 drive means 5 Fig. 1, and 6 Fig. 1. to move the carriage 2 and the positioning mechanism 3 respectively linearly relative to one another and to provide translational movement of the nozzle support from a position in which a nozzle carried thereby is above one receptacle to a position in which said nozzle is above another receptacle and movement of the nozzle support while said nozzle is in register with predetermined receptacles between an upper and lower position which the nozzle is spaced above the receptacle and a lower position in, which the nozzle extends into the receptacle and a measuring device 8, Fig. 12, operable to extract liquidfrom or dispense liquid into predetermined receptacles only when the nozzle support is in its lower position. The positioning mechanism 3, Fig. 2, comprises a nut 14 on a lead screw 15 coupled with motor 16 which is rotated intermittently to move mechanism 3 step by step. The nozzle support 4 is carried by arm 13 and comprises first and second pivoted frames 48, 49 each of generally parallelogramme formation arranged in spaced apart vertical planes, frame 48 being coupled with motor 17 to be pivoted about pivots 52 and 54 between upper and lower positions, bars 53, 55 and 64 remaining vertical. Bars 55 and 64 support nozzles in spring wire loops 78, Fig. 3. Thus when motor shaft 13a, Fig. 2, causes frame 48 to move from its upper to its lower position via link 48, and if at this time bar 81 engages a tongue on castellated edge 82 frame 49 remains in its upper position and as frame 48 rotates towards its lower position spring 71a, Fig. 3, urges the auxilliary arm 71 along side arm 67 so that nozzles carried by extensions 75 and 77 may extend into the same test tube. However, if bar 81 register with a recess in edge 82 the second frame 49 will be carried down with the first frame 48 with the inclined lower surface of plate 74 resting on the roller 73 so urging arm 71 towards arm 68 so that nozzles carried by extension 76, 77 will dip into the same test tube. When frame 48 is raised again it will cause frame 49 up with it by the interaction of the roller 73 and the plate 74. The measuring device 8, Fig. 12 comprises a replaceable base board 88, Fig. 14, carrying a plurality of syringes 90 together with a rotatable slide valve 91 which enables the syringes 90 connected thereto to be separately connected with nozzles 79 and 80 or externally of the apparatus to reagent reservoirs. The syringes 90 are operated by the rotation of crank 20, Fig. 1 in shaft 18 via connecting rod 97 and drive member 95, and the extent of the movement of member 90 and hence the quantity of liquid sucked in and discharged by the syringes 90 is controlled by the adjustable stop 117. Thus as shown in Fig. 12 in which the mechanism is shown in reverse compared to the mechanism 21 in Fig. 1, as shaft 18 rotates, bar 105 is moved to the right via connecting rod 97 where it engages pad 107 and then moves connected bar 95 to the right without compressing spring 109 and liquid is drawn into the syringe 90 until stop 117 prevents further movement of bar 95 to the right. Further movement of bar 105 compresses lost motion spring 109. Bar 105 is allowed to complete its stroke by compressing spring 109, during which ‘time bar 99’engages end 113 of bell carnk lever 110 to operate valve 91 to reconnect the syringes appropriately. Bar 105, and hence bar 95 is then urged to the left by connecting rod 97 thus causing discharge from syringes 90 until further movement of bar 105 and bar 95 is prevented by stop 119. The rest of the movement of bar 99, is taken up about fixed pivot 102 by extension of lost motion spring 104, during which time bar 99 contacts end 112 of bell crank lever 110 to readjust valve 91. Micro switches 23 operated by cams 22 carried on shaft 18 serve through timing control 26 to correlate operation of motors 16, 17 and 19, Fig. 1. Thus with positioning mechanism 3 positioned as in Fig. 1, motor 17 is energised by a micro switch acting through control 26 to move nozzle support 4 to its lowermost position, where motor 17 is deenergised by control 26. After appropriate delay control 26 energises motor 19 to operate syringes 90 during the first half revolution of crank 20. Near the end of this first half revolution control 26 energises motor 17 to lift the nozzle support to its uppermost position. A micro switch 22 then causes energisation of the motor 16 to drive lead screw 15 to move positioning mechanism 3 through a distance equal to one tube pitch. Another micro switch then energises motor 17 to lower the nozzle support as before and the second half of the revolution of crank 20 causes liquid in the springes to be dispensed. Motor 17 is then energised to lift the nozzle support as before and the motor 16 to move the positioning mechanism. Throughout this time the drum 28 has been steadily driven from shaft 18 via a chain 25 to move carriage 2 inwardly of the apparatus, the lead screw 15 being at an acute angle to the direction of movement of the carriage. The carriage 2 may contain a water bath and resting trays containing the receptacles as described in Specification, 1,205,752.

GB33226/66A
1966-07-23
1966-07-23
Improvements relating to multiple pipetting apparatus

Expired

GB1205751A
(en)

Priority Applications (4)

Application Number
Priority Date
Filing Date
Title

GB33226/66A

GB1205751A
(en)

1966-07-23
1966-07-23
Improvements relating to multiple pipetting apparatus

SE10770/67*A

SE357620B
(en)

1966-07-23
1967-07-21

DE1648818A

DE1648818B2
(en)

1966-07-23
1967-07-24

Pipetting device

US871609A

US3551112A
(en)

1966-07-23
1969-11-03
Multiple pipetting apparatus

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

GB33226/66A

GB1205751A
(en)

1966-07-23
1966-07-23
Improvements relating to multiple pipetting apparatus

Publications (1)

Publication Number
Publication Date

GB1205751A
true

GB1205751A
(en)

1970-09-16

Family
ID=10350183
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB33226/66A
Expired

GB1205751A
(en)

1966-07-23
1966-07-23
Improvements relating to multiple pipetting apparatus

Country Status (4)

Country
Link

US
(1)

US3551112A
(en)

DE
(1)

DE1648818B2
(en)

GB
(1)

GB1205751A
(en)

SE
(1)

SE357620B
(en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3767364A
(en)

*

1971-07-30
1973-10-23
Sherwood Medical Ind Inc
Reagent pipette system

FI55093C
(en)

*

1974-07-05
1979-05-10
Osmo Antero Suovaniemi

FOERFARANDE FOER EXAKT MAETNING AV ABSORPTION AV SMAO VAETSKEMAENGDER SAMT ANORDNING FOER DESS GENOMFOERANDE

JPS56132567A
(en)

*

1980-03-20
1981-10-16
Toshiba Corp
Automatic chemical analyzer

AU531969B2
(en)

*

1980-03-31
1983-09-15
Tokyo Shibaura Denki Kabushiki Kaisha
Automated chemical analytic apparatus

JPS56142460A
(en)

*

1980-04-08
1981-11-06
Toshiba Corp
Automatic chemical analyzing device

US4820497A
(en)

*

1986-06-23
1989-04-11
E. I. Du Pont De Nemours And Company
Movable cleaning assembly for an aspirating needle

CN101602022B
(en)

*

2009-07-20
2011-08-17
中国检验检疫科学研究院
Automatic rotating liquid adding and extracting volume fixing device

CN106000499A
(en)

*

2016-05-31
2016-10-12
四川金域医学检验中心有限公司
Examination test tube

1966

1966-07-23
GB
GB33226/66A
patent/GB1205751A/en
not_active
Expired

1967

1967-07-21
SE
SE10770/67*A
patent/SE357620B/xx
unknown

1967-07-24
DE
DE1648818A
patent/DE1648818B2/en
active
Granted

1969

1969-11-03
US
US871609A
patent/US3551112A/en
not_active
Expired – Lifetime

Also Published As

Publication number
Publication date

DE1648818C3
(en)

1975-10-23

DE1648818B2
(en)

1975-01-16

SE357620B
(en)

1973-07-02

US3551112A
(en)

1970-12-29

DE1648818A1
(en)

1972-06-08

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Legal Events

Date
Code
Title
Description

1971-01-27
PS
Patent sealed [section 19, patents act 1949]

1976-09-02
PLE
Entries relating assignments, transmissions, licences in the register of patents

1977-04-14
PLE
Entries relating assignments, transmissions, licences in the register of patents

1982-02-24
PCNP
Patent ceased through non-payment of renewal fee

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