GB1220623A – 0,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives
– Google Patents
GB1220623A – 0,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives
– Google Patents
0,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives
Info
Publication number
GB1220623A
GB1220623A
GB21907/68A
GB2190768A
GB1220623A
GB 1220623 A
GB1220623 A
GB 1220623A
GB 21907/68 A
GB21907/68 A
GB 21907/68A
GB 2190768 A
GB2190768 A
GB 2190768A
GB 1220623 A
GB1220623 A
GB 1220623A
Authority
GB
United Kingdom
Prior art keywords
substituted
dioxy
dihydro
oxo
methylene
Prior art date
1967-05-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21907/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1967-05-18
Filing date
1968-05-08
Publication date
1971-01-27
1968-05-08
Application filed by Warner Lambert Pharmaceutical Co
filed
Critical
Warner Lambert Pharmaceutical Co
1971-01-27
Publication of GB1220623A
publication
Critical
patent/GB1220623A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 – C07D459/00, C07D463/00, C07D477/00 or C07D489/00
C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 – C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
C07D491/04—Ortho-condensed systems
Abstract
1,220,623. 6,7 – Methylenedioxyquinoline derivatives. WARNER-LAMBERT PHARMACEUTICAL CO. 8 May, 1968 [18 May, 1967], No. 21907/68. Heading C2C. [Also in Division A5] The invention comprises compounds of formula wherein R is C 1-12 alkyl (possibly OH- or CO 2 H-substituted), C 2-12 alkenyl or C 3-8 cycloalkyl, and R 1 is NHOH, NHCOOR 2 , NHC 6 – H 4 OCH 3 or OCH 2 CH 2 N(R 2 ) 2 , where R 2 is C 1-12 alkyl. These compounds are prepared by reacting the acid chloride (above formula, R 1 Cl) with NH 2 OH, NH 2 COOR 2 , NH 2 C 6 H 4 – OCH 3 or HOCH 2 CH 2 N(R 2 ) 2 .
GB21907/68A
1967-05-18
1968-05-08
0,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives
Expired
GB1220623A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US63930467A
1967-05-18
1967-05-18
Publications (1)
Publication Number
Publication Date
GB1220623A
true
GB1220623A
(en)
1971-01-27
Family
ID=24563571
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB21907/68A
Expired
GB1220623A
(en)
1967-05-18
1968-05-08
0,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives
Country Status (6)
Country
Link
US
(1)
US3524858A
(en)
CA
(1)
CA918665A
(en)
DE
(1)
DE1770447A1
(en)
FR
(1)
FR8415M
(en)
GB
(1)
GB1220623A
(en)
SE
(1)
SE342450B
(en)
Families Citing this family (31)
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Publication number
Priority date
Publication date
Assignee
Title
DE1194219B
(en)
*
1962-01-12
1965-06-03
Schaefer & Kind Armaturenfabri
Quick-acting shut-off valve with a non-rising twist grip
US3966743A
(en)
*
1968-07-23
1976-06-29
Boehringer Mannheim G.M.B.H.
Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives
US3907808A
(en)
*
1971-05-17
1975-09-23
Sterling Drug Inc
1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
US3755332A
(en)
*
1971-07-01
1973-08-28
Ciba Geigy Corp
Substituted 4 indazolaminoquinolines
BE793524A
(en)
*
1971-12-30
1973-06-29
Riker Laboratories Inc
BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES
US4014877A
(en)
*
1972-11-02
1977-03-29
Riker Laboratories, Inc.
Substituted benzo[ij]quinolizine-2-carboxylic acids and derivatives thereof
US3985882A
(en)
*
1972-11-02
1976-10-12
Riker Laboratories, Inc.
Substituted benzo[ij]quinolinzine-2-carboxylic acids and derivatives thereof as bactericidal agents
US3905982A
(en)
*
1973-07-23
1975-09-16
Searle & Co
1-Aryl-n-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related compounds
US4001244A
(en)
*
1973-07-23
1977-01-04
G. D. Searle & Co.
1-aryl-3,4-dihydro-2(1h)-isoquinoline carbonyl chlorides
FR2281761A1
(en)
*
1974-08-13
1976-03-12
Roussel Uclaf
NEW DERIVATIVES OF 3-QUINOLEINE CARBOXYLIC ACID, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS A MEDICINAL PRODUCT
US4192876A
(en)
*
1975-07-23
1980-03-11
Sandoz, Inc.
4-Hydroxy-3-nitro-quinoline-2(1H)-ones
JPS5324028A
(en)
*
1976-08-19
1978-03-06
Sumitomo Chem Co Ltd
Systemic bactericide for plant
US4273930A
(en)
*
1977-06-20
1981-06-16
Sandoz, Inc.
4-Hydroxy-2-quinolinone-3-carboxylic acid esters
US4281131A
(en)
*
1977-06-20
1981-07-28
Sandoz, Inc.
4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4216324A
(en)
*
1978-12-26
1980-08-05
E. I. Du Pont De Nemours And Company
1-Difluoromethyl-6,7-methylenedioxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
US4284777A
(en)
*
1978-12-26
1981-08-18
E. I. Du Pont De Nemours And Company
Antibacterials: 1-difluoromethyl-6,7-methylenedioxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and its esters
IE52670B1
(en)
*
1981-03-03
1988-01-20
Leo Ab
Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
FR2564832B1
(en)
*
1984-05-23
1987-05-15
Panmedica Sa
NOVEL N-ACYL DERIVATIVES OF AMINO ACIDS AND THEIR ESTERS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
MX9800921A
(en)
*
1995-08-02
1998-05-31
Chirotech Technology Ltd
Quinolones and their therapeutic use.
AU696390B2
(en)
*
1995-08-02
1998-09-10
Darwin Discovery Limited
Quinolones and their therapeutic use
US20100074949A1
(en)
2008-08-13
2010-03-25
William Rowe
Pharmaceutical composition and administration thereof
US8354427B2
(en)
*
2004-06-24
2013-01-15
Vertex Pharmaceutical Incorporated
Modulators of ATP-binding cassette transporters
EP2502913A3
(en)
*
2004-06-24
2013-11-27
Vertex Pharmaceuticals Incorporated
Modulators of ATP-binding cassette transporters
RU2525115C2
(en)
*
2004-06-24
2014-08-10
Вертекс Фармасьютикалз Инкорпорейтед
Method of modulating transporters of atp-binding cassette
PL2502911T3
(en)
*
2004-06-24
2017-09-29
Vertex Pharma
Modulators of ATP-binding cassette transporters
CA2634113A1
(en)
*
2005-12-24
2007-07-05
Vertex Pharmaceuticals Incorporated
Quinolin- 4 – one derivatives as modulators of abc transporters
ES2790700T3
(en)
2005-12-28
2020-10-28
Vertex Pharma
Pharmaceutical compositions of the amorphous form of N- [2,4-bis (1,1-dimethylethyl) -5-hydroxyphenyl] -1,4-dihydro-4-oxoquinoline-3-carboxamide
SG10201504084QA
(en)
2009-03-20
2015-06-29
Vertex Pharma
Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2
(en)
2010-12-10
2014-08-12
Vertex Pharmaceuticals Incorporated
Modulators of ATP-Binding Cassette transporters
CN104470518A
(en)
2012-02-27
2015-03-25
沃泰克斯药物股份有限公司
Pharmaceutical composition and administration thereof
JP6746569B2
(en)
2014-10-07
2020-08-26
バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ
Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
Family Cites Families (5)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3172811A
(en)
*
1965-03-09
Quinolone proteus infection
treatment
US2614121A
(en)
*
1946-03-01
1952-10-14
Charles C Price
Process for making intermediates for producing basic compounds
FR1505313A
(en)
*
1962-04-09
1967-12-15
Norwich Pharma Co
Lower alkyl esters of 6, 7-dialkoxy (lower) -4-hydroxy-3-quinoline carboxylic acids and process for their preparation
GB1076828A
(en)
*
1963-12-12
1967-07-26
Warner Lambert Pharmaceutical
Methylenedioxy quinoline derivatives
US3397208A
(en)
*
1965-02-24
1968-08-13
Norwich Pharma Co
Method for preparing 4-hydroxy-6, 7-dialkoxy-3-carboalkoxyquinolines and novel 4-chloro-6, 7-dialkoxy-3-carboalkoxyquinolines useful therein
1967
1967-05-18
US
US639304A
patent/US3524858A/en
not_active
Expired – Lifetime
1968
1968-05-08
GB
GB21907/68A
patent/GB1220623A/en
not_active
Expired
1968-05-17
FR
FR152381A
patent/FR8415M/fr
not_active
Expired
1968-05-17
CA
CA020366A
patent/CA918665A/en
not_active
Expired
1968-05-17
DE
DE19681770447
patent/DE1770447A1/en
active
Pending
1968-05-17
SE
SE6739/68A
patent/SE342450B/xx
unknown
Also Published As
Publication number
Publication date
US3524858A
(en)
1970-08-18
CA918665A
(en)
1973-01-09
SE342450B
(en)
1972-02-07
DE1770447A1
(en)
1972-03-16
FR8415M
(en)
1971-06-10
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