GB1249443A

GB1249443A – New pyrazine derivatives
– Google Patents

GB1249443A – New pyrazine derivatives
– Google Patents
New pyrazine derivatives

Info

Publication number
GB1249443A

GB1249443A
GB02321/70A
GB1232170A
GB1249443A
GB 1249443 A
GB1249443 A
GB 1249443A
GB 02321/70 A
GB02321/70 A
GB 02321/70A
GB 1232170 A
GB1232170 A
GB 1232170A
GB 1249443 A
GB1249443 A
GB 1249443A
Authority
GB
United Kingdom
Prior art keywords
alkyl
march
alkoxy
pyrazine derivatives
new pyrazine
Prior art date
1969-03-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB02321/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1969-03-26
Filing date
1970-03-13
Publication date
1971-10-13

1970-03-13
Application filed by Carlo Erba SpA
filed
Critical
Carlo Erba SpA

1971-10-13
Publication of GB1249443A
publication
Critical
patent/GB1249443A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings

C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members

C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

1,249,443. Sulphonyl-ureas. CARLO ERBA S.p.A. 13 March, 1970 [26 March, 1969; 18 June, 1969], No. 12321/70. Heading C2C. Novel compounds (I) where R1, R2 and R3 are H, halogen, optionally substituted alkyl, alkoxy, OH, NH 2 , Ph or MeCONH and R4 is alkyl, alkenyl or an unsubstituted or alkyl- or alkoxy-substituted cycloaliphatic hydrocarbon, are made according to standard methods. 4 – [# – (2 – Pyrazineamido) ethyl] – benzene sulphonamide is prepared by interacting pyrazine-2-carboxylic acid chloride and p-(#-aminoethyl)-benzenesulphonamide. Pharmaceutical preparations having hypoglycaemic action contain (I) as active ingredient; administration is preferably orally.

GB02321/70A
1969-03-26
1970-03-13
New pyrazine derivatives

Expired

GB1249443A
(en)

Applications Claiming Priority (2)

Application Number
Priority Date
Filing Date
Title

IT1458169

1969-03-26

IT1830169

1969-06-18

Publications (1)

Publication Number
Publication Date

GB1249443A
true

GB1249443A
(en)

1971-10-13

Family
ID=26326731
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB02321/70A
Expired

GB1249443A
(en)

1969-03-26
1970-03-13
New pyrazine derivatives

Country Status (14)

Country
Link

US
(1)

US3669966A
(en)

BE
(1)

BE747405A
(en)

CA
(1)

CA952112A
(en)

CH
(1)

CH547809A
(en)

CY
(1)

CY645A
(en)

DE
(1)

DE2012138C3
(en)

DK
(1)

DK128320B
(en)

FI
(1)

FI52720C
(en)

FR
(1)

FR2035890B1
(en)

GB
(1)

GB1249443A
(en)

IL
(1)

IL34153A
(en)

MY
(1)

MY7300007A
(en)

NL
(1)

NL138933B
(en)

NO
(1)

NO127399B
(en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE3320583A1
(en)

*

1983-06-08
1984-12-13
Dr. Karl Thomae Gmbh, 7950 Biberach

NEW GALENIC PREPARATION FORMS OF ORAL ANTIDIABETICS AND METHOD FOR THE PRODUCTION THEREOF

DE3320582A1
(en)

*

1983-06-08
1984-12-13
Dr. Karl Thomae Gmbh, 7950 Biberach

METHODS OF PREPARATION WITH GLIQUIDONE AND METHOD FOR THE PRODUCTION THEREOF

US5196410A
(en)

*

1986-10-31
1993-03-23
Pfizer Inc.
Transdermal flux enhancing compositions

US6361795B1
(en)

1989-09-05
2002-03-26
Alza Corporation
Method for lowering blood glucose

US5516906A
(en)

*

1995-01-17
1996-05-14
Usv Limited
Process for the preparation of N-[2-[4-(aminosulfonyl) phenyl]ethyl]5-methylpyrazinecarboxamide

US8236352B2
(en)

*

1998-10-01
2012-08-07
Alkermes Pharma Ireland Limited
Glipizide compositions

US7041691B1
(en)

*

1999-06-30
2006-05-09
Amgen Inc.
Compounds for the modulation of PPARγ activity

AU6118001A
(en)

*

2000-05-03
2001-11-12
Tularik Inc
Combination therapeutic compositions and methods of use

US20030171399A1
(en)

*

2000-06-28
2003-09-11
Tularik Inc.
Quinolinyl and benzothiazolyl modulators

US8268352B2
(en)

*

2002-08-05
2012-09-18
Torrent Pharmaceuticals Limited
Modified release composition for highly soluble drugs

US8216609B2
(en)

2002-08-05
2012-07-10
Torrent Pharmaceuticals Limited
Modified release composition of highly soluble drugs

US7223761B2
(en)

2003-10-03
2007-05-29
Amgen Inc.
Salts and polymorphs of a potent antidiabetic compound

US20070025953A1
(en)

*

2005-07-27
2007-02-01
Jones Michael R
Co-therapy for diabetic conditions

CN107501407B
(en)

2007-03-30
2022-03-18
Ambrx公司
Modified FGF-21 polypeptides and uses thereof

TW202124419A
(en)

2014-10-24
2021-07-01
美商必治妥美雅史谷比公司
Modified fgf-21 polypeptides and uses thereof

CN105399692A
(en)

*

2015-12-18
2016-03-16
四川大学
Glipizide crystal form III, and preparation method thereof

WO2018078657A1
(en)

*

2016-10-28
2018-05-03
J.B. Chemicals & Pharmaceuticals Limited
Process for preparation of glipizide

Family Cites Families (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE1185180B
(en)

*

1963-10-19
1965-01-14
Hoechst Ag

Process for the preparation of benzenesulfonylureas

NL6707184A
(en)

*

1966-06-06
1967-12-07

US3573305A
(en)

*

1968-12-30
1971-03-30
Merck & Co Inc
(3-amino-pyrazinoyl)sulfamides and their preparation

1969

1969-10-17
NL
NL696915776A
patent/NL138933B/en
not_active
IP Right Cessation

1970

1970-02-20
FR
FR7006139A
patent/FR2035890B1/fr
not_active
Expired

1970-03-13
GB
GB02321/70A
patent/GB1249443A/en
not_active
Expired

1970-03-14
DE
DE2012138A
patent/DE2012138C3/en
not_active
Expired

1970-03-16
BE
BE747405D
patent/BE747405A/en
not_active
IP Right Cessation

1970-03-20
FI
FI700791A
patent/FI52720C/en
active

1970-03-24
US
US22389A
patent/US3669966A/en
not_active
Expired – Lifetime

1970-03-24
IL
IL34153A
patent/IL34153A/en
unknown

1970-03-25
NO
NO01138/70A
patent/NO127399B/no
unknown

1970-03-25
CH
CH454470A
patent/CH547809A/en
not_active
IP Right Cessation

1970-03-25
CA
CA078,355A
patent/CA952112A/en
not_active
Expired

1970-03-25
DK
DK152570AA
patent/DK128320B/en
not_active
IP Right Cessation

1972

1972-06-16
CY
CY64572A
patent/CY645A/en
unknown

1973

1973-12-30
MY
MY7/73A
patent/MY7300007A/en
unknown

Also Published As

Publication number
Publication date

CY645A
(en)

1972-06-16

IL34153A0
(en)

1970-05-21

US3669966A
(en)

1972-06-13

NL6915776A
(en)

1970-09-29

DK128320B
(en)

1974-04-08

DE2012138C3
(en)

1978-08-10

FI52720B
(en)

1977-08-01

CH547809A
(en)

1974-04-11

FR2035890A1
(en)

1970-12-24

DE2012138B2
(en)

1977-12-15

FI52720C
(en)

1977-11-10

NO127399B
(en)

1973-06-18

MY7300007A
(en)

1973-12-31

FR2035890B1
(en)

1974-01-11

CA952112A
(en)

1974-07-30

DE2012138A1
(en)

1970-10-01

IL34153A
(en)

1972-12-29

NL138933B
(en)

1973-05-15

BE747405A
(en)

1970-08-31

Similar Documents

Publication
Publication Date
Title

GB1249443A
(en)

1971-10-13

New pyrazine derivatives

EP0214659A3
(en)

1988-07-27

Peptide derivatives, process for the production thereof and pharmaceutical compositions containing same

ES482153A1
(en)

1980-08-16

Phenethanolamines, their formulations, preparation and use.

GB1337280A
(en)

1973-11-14

5-phenyl-isoxazole-3-carboxylic acids and their derivatives

GB1289240A
(en)

1972-09-13

ES8405616A1
(en)

1984-06-16

3-Aryl-7-chloro-3,4-dihydro-acridine-1,9-(2H,10H)-dione-1-oximes and 1-hydrazones, their salts, process for their preparation and pharmaceutical preparations containing them, and their application.

GB1475314A
(en)

1977-06-01

Phenyl-propylamine derivatives

GB1254414A
(en)

1971-11-24

Novel aminoethanesulfonylamino derivatives and their production

GB1296133A
(en)

1972-11-15

GB1362400A
(en)

1974-08-07

1-amino-isoquinoline derivatives

GB1314899A
(en)

1973-04-26

Thiosemicarbazones processes for their preparations and compositions incorporating them

GB1449404A
(en)

1976-09-15

N-arylsulphonyl urea derivatives

GB1503626A
(en)

1978-03-15

Substituted piperazine derivative its preparation and compositions containing it

GB1302353A
(en)

1973-01-10

GB1199758A
(en)

1970-07-22

Arylsulphonyl-Semicarbazides and their production

GB1470780A
(en)

1977-04-21

Pyridine derivatives

GB1342643A
(en)

1974-01-03

Thioacetanilide derivatives

GB1298057A
(en)

1972-11-29

Bis(aminoalkylsulphamoyl)anthraquinones

GB1444558A
(en)

1976-08-04

Pyridylthioureas

GB1173809A
(en)

1969-12-10

N-Substituted Nor-Morphines

GB1426685A
(en)

1976-03-03

1,3-bis -beta-ethylhexyl-5 amino-5-methylhexahydropyrimidine- pyridine-3-carboxylate

GB1195319A
(en)

1970-06-17

Alkyl Sulfate Salts of 1-(p-Chlorobenzhydryl)-4-Methylhomopiperazines

GB1317099A
(en)

1973-05-16

3-sulphamyl-4-chlorobenzoic acid derivatives

GB1386028A
(en)

1975-03-05

Alpha-aminoalkyl-4-hydroxy-3-alkylsulphonylmethylbenzyl alcohols

GB1306396A
(en)

1973-02-07

Legal Events

Date
Code
Title
Description

1972-02-23
PS
Patent sealed [section 19, patents act 1949]

1986-04-03
732
Registration of transactions, instruments or events in the register (sect. 32/1977)

1986-12-31
746B
Proceeding under section 46(3) patents act 1977

1987-04-15
746D
Case decided by the comptroller (sect. 46(3)/1977)

1988-09-28
746D
Case decided by the comptroller (sect. 46(3)/1977)

1989-02-08
746B
Proceeding under section 46(3) patents act 1977

1990-04-11
PE20
Patent expired after termination of 20 years

1990-06-06
746B
Proceeding under section 46(3) patents act 1977

Download PDF in English

None