GB1268243A – 0,2,4,5,-tetrahydro-3h,3-benzazepines
– Google Patents
GB1268243A – 0,2,4,5,-tetrahydro-3h,3-benzazepines
– Google Patents
0,2,4,5,-tetrahydro-3h,3-benzazepines
Info
Publication number
GB1268243A
GB1268243A
GB1284469A
GB1284469A
GB1268243A
GB 1268243 A
GB1268243 A
GB 1268243A
GB 1284469 A
GB1284469 A
GB 1284469A
GB 1284469 A
GB1284469 A
GB 1284469A
GB 1268243 A
GB1268243 A
GB 1268243A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
phenyl
lower alkyl
alkyl
substituted
Prior art date
1968-03-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1284469A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Filter Wallace and Tiernan Inc
Original Assignee
Wallace and Tiernan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1968-03-11
Filing date
1969-03-11
Publication date
1972-03-22
1969-03-11
Application filed by Wallace and Tiernan Inc
filed
Critical
Wallace and Tiernan Inc
1972-03-22
Publication of GB1268243A
publication
Critical
patent/GB1268243A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
C07D223/16—Benzazepines; Hydrogenated benzazepines
Abstract
1,268,243. Benzazepine derivatives. WALLACE & TIERNAN Inc. 11 March, 1969 [11 March, 1968], No. 12844/69. Heading C2C. Novel compounds I or the pharmaceutically acceptable addition salts thereof, wherein R is H, lower alkyl, dialkylaminoalkyl; lower alkenyl containing 3-6 carbon atoms; aryl-C 3 -C 6 alkenyl; cycloalkyl-alkyl; aryl-cylcoalkyl-alkyl; propargyl; aryl-lower alkyl, the aryl group selected from phenyl, tolyl, nitrophenyl, aminophenyl, acylaminophenyl, methoxyphenyl, hydroxyphenyl, methylaminophenyl, ethylaminophenyl, or dimethylaminophenyl; a lower alkyl ester of hydroxyalkyl; a heterocyclic group, an alkyl group substituted by a heterocyclic ring (unsubstituted or substituted with one or more phenyl, hydroxyl or acyl groups), 2-phthalimidoethyl- (the phenyl moiety unsubstituted or substituted in any of the remaining positons with NH 2 , OH, OCH 3 , halogen, alkyl); 2-(2- isoindolinyl)-ethyl- (the phenyl moiety unsubstituted or substituted in any of the remaining positions with NH 2 , OH, OCH 3 , halogen, alkyl); 2 – [4 – benzyl – 1 – piperazinyl] – ethyl- (the phenyl moiety unsubstituted or substituted in the o, m, or p-position with NH 2 , OH, OCH 3 ); 2 – (4 – phenyl – 1 – piperazinyl) – ethyl- (the phenyl moiety unsubstituted or substituted in the o, m, p-position with NH 2 , OH, OCH 3 , halogen, alkyl); 2-[4-(o-methylbenzyl)-1-piperazinyl]-ethyl- (the phenyl moiety unsubstituted or substituted in the o, m, or p-position with NH 2 , OH, OCH 3 , halogen, alkyl); R
GB1284469A
1968-03-11
1969-03-11
0,2,4,5,-tetrahydro-3h,3-benzazepines
Expired
GB1268243A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US71189768A
1968-03-11
1968-03-11
Publications (1)
Publication Number
Publication Date
GB1268243A
true
GB1268243A
(en)
1972-03-22
Family
ID=24859960
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB1284469A
Expired
GB1268243A
(en)
1968-03-11
1969-03-11
0,2,4,5,-tetrahydro-3h,3-benzazepines
Country Status (2)
Country
Link
CA
(1)
CA974989A
(en)
GB
(1)
GB1268243A
(en)
Cited By (34)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0005300A1
(en)
*
1978-05-08
1979-11-14
Technobiotic Ltd.
Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them
EP0007070A1
(en)
*
1978-07-07
1980-01-23
Smithkline Beckman Corporation
2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity
US4284556A
(en)
*
1980-01-31
1981-08-18
Smithkline Corporation
7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0044709A1
(en)
*
1980-07-17
1982-01-27
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1981-11-27
1983-06-08
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3-Benzazepines as alpha-2 antagonists
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1982-07-29
1984-03-28
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Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines
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*
1982-10-08
1984-05-16
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3-Benzazepines as alpha-2 antagonists
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1981-11-27
1985-01-29
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Pharmaceutical compositions and methods for producing alpha antagonism
WO1985000808A1
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1983-08-12
1985-02-28
Schering Corp.
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1985-01-17
1986-07-30
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1985-12-20
1987-04-21
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1985-12-20
1987-11-17
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1987-03-25
1988-09-28
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WO1988007526A1
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1987-03-27
1988-10-06
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Substituted benzazepines, their preparation and pharmaceutical compositions containing them
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1988-06-15
1989-12-27
Novo Nordisk A/S
Benzazepine derivatives
EP0383247A1
(en)
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1989-02-14
1990-08-22
Novo Nordisk A/S
Benzazepines with antidopaminergic activity
US5015639A
(en)
*
1987-03-27
1991-05-14
Schering Corporation
Substituted benzazepines, their preparation and pharmaceutical compositions containing them
WO2002074746A1
(en)
*
2001-03-16
2002-09-26
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2003-06-17
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Method for preparing 3-benzazepine
EP2133340A1
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2002-12-20
2009-12-16
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1969
1969-03-11
GB
GB1284469A
patent/GB1268243A/en
not_active
Expired
1969-03-11
CA
CA045,388A
patent/CA974989A/en
not_active
Expired
Cited By (72)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0005300A1
(en)
*
1978-05-08
1979-11-14
Technobiotic Ltd.
Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them
EP0007070A1
(en)
*
1978-07-07
1980-01-23
Smithkline Beckman Corporation
2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity
EP0080012A1
(en)
*
1978-07-07
1983-06-01
Smithkline Beckman Corporation
6-Chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, its acid addition salts and its use as an intermediate
US4284556A
(en)
*
1980-01-31
1981-08-18
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7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0044709A1
(en)
*
1980-07-17
1982-01-27
Smithkline Beckman Corporation
New dopaminergic benzazepines
US4496558A
(en)
*
1981-11-27
1985-01-29
Smithkline Beckman Corporation
Pharmaceutical compositions and methods for producing alpha antagonism
EP0080779A1
(en)
*
1981-11-27
1983-06-08
Smithkline Beckman Corporation
3-Benzazepines as alpha-2 antagonists
EP0103961A1
(en)
*
1982-07-29
1984-03-28
Smithkline Beckman Corporation
Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0108170A1
(en)
*
1982-10-08
1984-05-16
Smithkline Beckman Corporation
3-Benzazepines as alpha-2 antagonists
WO1985000808A1
(en)
*
1983-08-12
1985-02-28
Schering Corp.
Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
EP0135767A1
(en)
*
1983-08-12
1985-04-03
Schering Corporation
Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
GB2170197A
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*
1985-01-17
1986-07-30
Ici Plc
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US4659706A
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*
1985-12-20
1987-04-21
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US4707483A
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*
1985-12-20
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US4891372A
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*
1987-03-25
1990-01-02
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*
1987-03-25
1988-09-28
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Substituted benzazepines, their preparation and pharmaceutical compositions containing them
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Substituted benzazepines, their preparation and pharmaceutical compositions containing them
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1988-10-06
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Substituted benzazepines, their preparation and pharmaceutical compositions containing them
EP0347672A1
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1988-06-15
1989-12-27
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EP0383247A1
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1989-02-14
1990-08-22
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US5079243A
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*
1989-02-14
1992-01-07
Novo Nordisk A/S
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WO2002074746A1
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2001-03-16
2002-09-26
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Also Published As
Publication number
Publication date
CA974989A
(en)
1975-09-23
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(en)
1988-12-13
4-(isoxazolyl)-thiazole-2- oxamic acids and derivatives thereof
ES8400743A1
(en)
1983-11-01
1-Phenylindazol-3-one compounds, process and intermediates for their preparation and medicines containing these compounds.
DE3264708D1
(en)
1985-08-22
4-aryloxy-1,2,3,4-tetrahydroisoquinolines, and intermediates, a process for preparing the same, a pharmaceutical composition containing the same and their use as medicaments
ES8405020A1
(en)
1984-05-16
Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same.
IE39042L
(en)
1975-05-28
Ergoline derivatives
IE40722B1
(en)
1979-08-01
Indolopiperdino-alkylthiazines
JPS5524127A
(en)
1980-02-21
3,6-endomethylene-delta4-1,2,3,6-tetrahydrophtalimide derivative
JPS5527142A
(en)
1980-02-27
Novel 1-phthalazone derivative
ES8300114A1
(en)
1982-10-01
Thiovinyl-3-cephalosporin derivatives, their preparation and pharmaceutical compositions containing them.
JPS572289A
(en)
1982-01-07
Production of penem-3-carboxylic derivative
JPS525797A
(en)
1977-01-17
Preparation of tetrahydropyrido pyrimidinone derivatives
None