GB1297411A – – Google Patents
GB1297411A – – Google Patents
Info
Publication number
GB1297411A
GB1297411A
GB1436570A
GB1297411DA
GB1297411A
GB 1297411 A
GB1297411 A
GB 1297411A
GB 1436570 A
GB1436570 A
GB 1436570A
GB 1297411D A
GB1297411D A
GB 1297411DA
GB 1297411 A
GB1297411 A
GB 1297411A
Authority
GB
United Kingdom
Prior art keywords
formula
compound
dopa
alkyl
forms
Prior art date
1970-03-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1436570A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-03-24
Filing date
1970-03-24
Publication date
1972-11-22
1970-03-24
Application filed
filed
Critical
1972-11-22
Publication of GB1297411A
publication
Critical
patent/GB1297411A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A61K31/19—Carboxylic acids, e.g. valproic acid
A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/13—Amines
A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A61K31/19—Carboxylic acids, e.g. valproic acid
A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
A61K9/1605—Excipients; Inactive ingredients
A61K9/1617—Organic compounds, e.g. phospholipids, fats
A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
A61K9/1605—Excipients; Inactive ingredients
A61K9/1629—Organic macromolecular compounds
A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/20—Pills, tablets, discs, rods
A61K9/2004—Excipients; Inactive ingredients
A61K9/2022—Organic macromolecular compounds
A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/20—Pills, tablets, discs, rods
A61K9/2004—Excipients; Inactive ingredients
A61K9/2022—Organic macromolecular compounds
A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
A61K9/4841—Filling excipients; Inactive ingredients
A61K9/4858—Organic compounds
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
A61K9/4841—Filling excipients; Inactive ingredients
A61K9/4866—Organic macromolecular compounds
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 – A61K41/00
Abstract
1297411 Antiparkinsonism &c medicines M SANDLER 19 April 1971 [24 March 1970 28 July 1970] 14365/70 and 36430/70 Heading A5B Pharmaceutical compositions useful in the treatment of depression and Parkinson’s disease comprise a compound of Formula I below together with a compound of Formula II below. Each may be in the form of a pharmaceutically acceptable salt, acid addition salt or a salt with an ion-exchange resin, the compositions suitably being in such forms as tablets. The formulae are: wherein R is H or alkoxycarbonyl and R 1 is H or -COOR 2 where R @ is H or alkyl, providing that R and R @ are not both H. “Alkyl” and “alkoxy” refer to such groups having up to 6 C atoms. The compounds are preferably in their L-forms, the preferred compound of Formula I being m-tyrosine. Formula II includes “dopa”, i.e. “L-dopa”.
GB1436570A
1970-03-24
1970-03-24
Expired
GB1297411A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB1436570
1970-03-24
Publications (1)
Publication Number
Publication Date
GB1297411A
true
GB1297411A
(en)
1972-11-22
Family
ID=10039897
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB1436570A
Expired
GB1297411A
(en)
1970-03-24
1970-03-24
Country Status (2)
Country
Link
GB
(1)
GB1297411A
(en)
ZA
(1)
ZA711821B
(en)
1970
1970-03-24
GB
GB1436570A
patent/GB1297411A/en
not_active
Expired
1971
1971-03-22
ZA
ZA711821A
patent/ZA711821B/en
unknown
Also Published As
Publication number
Publication date
ZA711821B
(en)
1971-12-29
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m-TYROSINE ESTERS
Legal Events
Date
Code
Title
Description
1973-04-04
PS
Patent sealed [section 19, patents act 1949]
1975-11-19
PLNP
Patent lapsed through nonpayment of renewal fees