GB1297476A

GB1297476A – – Google Patents

GB1297476A – – Google Patents

Info

Publication number
GB1297476A

GB1297476A

GB1297476DA
GB1297476A
GB 1297476 A
GB1297476 A
GB 1297476A

GB 1297476D A
GB1297476D A
GB 1297476DA
GB 1297476 A
GB1297476 A
GB 1297476A
Authority
GB
United Kingdom
Prior art keywords
acetate
active
propionate
water
glycol ether
Prior art date
1970-03-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-03-04
Filing date
1971-04-19
Publication date
1972-11-22

1971-04-19
Application filed
filed
Critical

1972-11-22
Publication of GB1297476A
publication
Critical
patent/GB1297476A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

A61K9/5005—Wall or coating material

A61K9/5021—Organic macromolecular compounds

A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin

A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

A61K9/1605—Excipients; Inactive ingredients

A61K9/1629—Organic macromolecular compounds

A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

A61K9/5005—Wall or coating material

A61K9/5021—Organic macromolecular compounds

A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin

A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K9/00—Medicinal preparations characterised by special physical form

A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

A61K9/5089—Processes

B—PERFORMING OPERATIONS; TRANSPORTING

B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL

B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS

B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons

B01J13/02—Making microcapsules or microballoons

B01J13/06—Making microcapsules or microballoons by phase separation

B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution

Abstract

1297476 Microgranulate FARBENFABRIKEN BAYER AG 19 April 1971 [4 March 1970] 22308/71 Heading A5B [Also in Division B8] Solid, free-flowing, substantially spherical particles (microgranulates) are prepared by dispersing or dissolving an “active” material in a solution of a cellulose ester in a glycol ether and introducing discrete droplets of the resultant into water whereby the glycol ether is given up to the water and the droplets become solidified and may be separated. Suitable cellulose esters are: cellulose acetate, propionate, propionate acetate and butyrate acetate preferably having 2.2 to 2.6 acyl radicals per anhydroglucose unit. Suitable glycol ethers are mono- and di-alkyl ethers of aliphatic glycols having 1 to 6 carbon atoms in the alkyl group. Examples relate to processes in which the “active” material is: aspirin, paraffin oil, TiO 2 and the compound (CH 3 O) 2 PO (CHOH-CCl 3 ).

GB1297476D
1970-03-04
1971-04-19

Expired

GB1297476A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

DE19702010116

DE2010116A1
(en)

1970-03-04
1970-03-04

Process for the production of micro-granules

Publications (1)

Publication Number
Publication Date

GB1297476A
true

GB1297476A
(en)

1972-11-22

Family
ID=5764038
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB1297476D
Expired

GB1297476A
(en)

1970-03-04
1971-04-19

Country Status (13)

Country
Link

JP
(1)

JPS5344424B1
(en)

AT
(1)

AT310127B
(en)

BE
(1)

BE763791A
(en)

CA
(1)

CA922588A
(en)

CH
(1)

CH549408A
(en)

CS
(1)

CS158290B2
(en)

DE
(1)

DE2010116A1
(en)

ES
(1)

ES388917A1
(en)

FR
(1)

FR2084200A5
(en)

GB
(1)

GB1297476A
(en)

IL
(1)

IL36222A
(en)

TR
(1)

TR16847A
(en)

ZA
(1)

ZA711052B
(en)

Cited By (8)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4609542A
(en)

*

1978-12-22
1986-09-02
Elan Corporation, P.L.C.
New pharmaceutical forms for administration of medicaments by oral route, with programmed release

WO1999055774A1
(en)

*

1998-04-24
1999-11-04
Eastman Chemical Company
Coprecipitation of cellulose esters with functional additives and compositions thus obtainable

EP1044683A1
(en)

*

1999-04-15
2000-10-18
Debio Recherche Pharmaceutique S.A.
One-step dispersion method for the microencapsulation of water soluble substances

EP1151741A1
(en)

*

2000-05-05
2001-11-07
L’oreal
Microcapsules with an aqueous core containing at least an active water-soluble cosmetic or dermatologic ingredient and cosmetic or dermatologic compositions containing these microcapsules

WO2005061095A1
(en)

*

2003-12-24
2005-07-07
Mg Pharmacy Inc.
Process for producing microsphere and apparatus for producing the same

US9156016B2
(en)

2010-09-30
2015-10-13
Midatech Pharma (Wales) Limited
Apparatus and method for making solid beads

US9259701B2
(en)

2010-09-30
2016-02-16
Q Chip Ltd.
Method for making solid beads

WO2019238892A1
(en)

*

2018-06-15
2019-12-19
Taminco Bvba
Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain

Families Citing this family (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4389330A
(en)

*

1980-10-06
1983-06-21
Stolle Research And Development Corporation
Microencapsulation process

DD160393A3
(en)

*

1980-11-14
1983-07-27
Horst Dautzenberg

MICRO CAPSULES AND METHOD FOR THE PRODUCTION THEREOF

JP2534691B2
(en)

*

1986-12-26
1996-09-18
トツパン・ム−ア株式会社

Method for producing high-density microcapsules

1970

1970-03-04
DE
DE19702010116
patent/DE2010116A1/en
active
Pending

1971

1971-02-17
IL
IL36222A
patent/IL36222A/en
unknown

1971-02-18
ZA
ZA711052A
patent/ZA711052B/en
unknown

1971-03-01
AT
AT173571A
patent/AT310127B/en
not_active
IP Right Cessation

1971-03-02
CA
CA106615A
patent/CA922588A/en
not_active
Expired

1971-03-03
CS
CS158871A
patent/CS158290B2/cs
unknown

1971-03-03
TR
TR16847A
patent/TR16847A/en
unknown

1971-03-03
CH
CH307871A
patent/CH549408A/en
not_active
IP Right Cessation

1971-03-04
JP
JP1101371A
patent/JPS5344424B1/ja
active
Pending

1971-03-04
ES
ES388917A
patent/ES388917A1/en
not_active
Expired

1971-03-04
FR
FR7107509A
patent/FR2084200A5/fr
not_active
Expired

1971-03-04
BE
BE763791A
patent/BE763791A/xx
unknown

1971-04-19
GB
GB1297476D
patent/GB1297476A/en
not_active
Expired

Cited By (12)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4609542A
(en)

*

1978-12-22
1986-09-02
Elan Corporation, P.L.C.
New pharmaceutical forms for administration of medicaments by oral route, with programmed release

WO1999055774A1
(en)

*

1998-04-24
1999-11-04
Eastman Chemical Company
Coprecipitation of cellulose esters with functional additives and compositions thus obtainable

EP1044683A1
(en)

*

1999-04-15
2000-10-18
Debio Recherche Pharmaceutique S.A.
One-step dispersion method for the microencapsulation of water soluble substances

WO2000062761A1
(en)

*

1999-04-15
2000-10-26
Debio Recherche Pharmaceutique S.A.
Process for microencapsulation of water soluble substances

US6777002B1
(en)

1999-04-15
2004-08-17
Debio Recherche Pharmaceutique S.A.
Process for microencapsulation of water soluble substances

EP1151741A1
(en)

*

2000-05-05
2001-11-07
L’oreal
Microcapsules with an aqueous core containing at least an active water-soluble cosmetic or dermatologic ingredient and cosmetic or dermatologic compositions containing these microcapsules

US6531160B2
(en)

2000-05-05
2003-03-11
L′Oreal
Microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle and cosmetic or dermatological compositions containing them

WO2005061095A1
(en)

*

2003-12-24
2005-07-07
Mg Pharmacy Inc.
Process for producing microsphere and apparatus for producing the same

US9156016B2
(en)

2010-09-30
2015-10-13
Midatech Pharma (Wales) Limited
Apparatus and method for making solid beads

US9259701B2
(en)

2010-09-30
2016-02-16
Q Chip Ltd.
Method for making solid beads

WO2019238892A1
(en)

*

2018-06-15
2019-12-19
Taminco Bvba
Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain

CN112334011A
(en)

*

2018-06-15
2021-02-05
塔明克公司
Treatment of poultry or pigs for reducing feed conversion ratio or increasing weight gain

Also Published As

Publication number
Publication date

FR2084200A5
(en)

1971-12-17

IL36222A0
(en)

1971-04-28

ES388917A1
(en)

1974-02-16

SU379074A3
(en)

1973-04-18

AT310127B
(en)

1973-09-25

TR16847A
(en)

1973-07-01

CH549408A
(en)

1974-05-31

IL36222A
(en)

1973-08-29

ZA711052B
(en)

1971-10-27

DE2010116A1
(en)

1971-09-16

CS158290B2
(en)

1974-10-15

BE763791A
(en)

1971-08-02

JPS5344424B1
(en)

1978-11-29

CA922588A
(en)

1973-03-13

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Legal Events

Date
Code
Title
Description

1973-04-04
PS
Patent sealed [section 19, patents act 1949]

1977-11-16
PLNP
Patent lapsed through nonpayment of renewal fees

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