GB1346791A – Process and intermediates for preparing benzamide compounds
– Google Patents
GB1346791A – Process and intermediates for preparing benzamide compounds
– Google Patents
Process and intermediates for preparing benzamide compounds
Info
Publication number
GB1346791A
GB1346791A
GB224071A
GB224071A
GB1346791A
GB 1346791 A
GB1346791 A
GB 1346791A
GB 224071 A
GB224071 A
GB 224071A
GB 224071 A
GB224071 A
GB 224071A
GB 1346791 A
GB1346791 A
GB 1346791A
Authority
GB
United Kingdom
Prior art keywords
methyl
formula
phthalimidobenzoate
methoxy
isopropyl
Prior art date
1970-01-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB224071A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-01-21
Filing date
1971-01-18
Publication date
1974-02-13
1971-01-18
Application filed by Delmar Chemicals Inc
filed
Critical
Delmar Chemicals Inc
1974-02-13
Publication of GB1346791A
publication
Critical
patent/GB1346791A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
C07D209/44—Iso-indoles; Hydrogenated iso-indoles
C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
Abstract
1346791 Phthalimides DELMAR CHEMICALS Ltd 18 Jan 1971 [21 Jan 1970] 2240/71 Heading C2C The invention comprises novel phthalimides of the Formula II wherein X is Cl or Br, and R 1 and R 2 each are H or alkyl and the conversion of the above compounds in which R 1 and R 2 are alkyl into benzamides of the Formula I wherein R is alkyl and Z is tertiary aminoalkyl, by reacting the said compounds under substantially anhydrous conditions with diamines of the formula ZNH 2 . The compounds of Formula II above are prepared by reacting the appropriate amines with phthalic anhydride, followed by or preceded by, esterification, alkylation and/or bromination or chlorination. Methyl 2-methoxy-4-phthalimidobenzoate is obtained by methylating methyl 4-phthalimidosalicylate, resulting from the reaction of phthalic anhydride on methyl 4-aminosalicylate, obtained by esterifying 4-aminosalicyclic acid. The first named compound may also be obtained by reacting dimethyl sulphate with 4-phthalimidosalicylic acid resulting from the reaction between phthalic anhydride and 4-aminosalicylic acid. Ethyl and isopropyl 4-aminosalicylate, ethyl and isopropyl 4-phthalimidosalicylate, and ethyl and isopropyl 2-methoxy-4-phthalimidobenzoate are obtained by similar processes. N – (2 – Diethylaminoethyl)phthalimide is obtained as a by-product in the reaction between N,N-diethylethylenediamine and methyl 5- chloro-2-methoxy-4-phthalimidobenzoate. Reference has been directed by the Comptroller to Specification 994,023.
GB224071A
1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds
Expired
GB1346791A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US458770A
1970-01-21
1970-01-21
Publications (1)
Publication Number
Publication Date
GB1346791A
true
GB1346791A
(en)
1974-02-13
Family
ID=21711507
Family Applications (2)
Application Number
Title
Priority Date
Filing Date
GB224071A
Expired
GB1346791A
(en)
1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds
GB4814872A
Expired
GB1346792A
(en)
1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds
Family Applications After (1)
Application Number
Title
Priority Date
Filing Date
GB4814872A
Expired
GB1346792A
(en)
1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds
Country Status (15)
Country
Link
JP
(2)
JPS5024B1
(en)
AT
(2)
AT335425B
(en)
BE
(1)
BE761820A
(en)
BR
(1)
BR7100323D0
(en)
CH
(1)
CH544086A
(en)
DE
(2)
DE2102848C3
(en)
DK
(1)
DK136032B
(en)
ES
(1)
ES387498A1
(en)
FI
(1)
FI57098C
(en)
FR
(1)
FR2077252B1
(en)
GB
(2)
GB1346791A
(en)
NL
(1)
NL7100795A
(en)
NO
(1)
NO132536C
(en)
SE
(3)
SE400776B
(en)
ZA
(1)
ZA71389B
(en)
Families Citing this family (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPH0825970B2
(en)
*
1987-09-01
1996-03-13
住友化学工業株式会社
Process for producing tetrahydrophthalimide compound, intermediate thereof and process for producing the intermediate
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DE1233877B
(en)
*
1961-07-25
1967-02-09
Ile De France
Process for the preparation of substituted N- (tert. Aminoalkyl) -benzamides
FR1407055A
(en)
*
1963-03-05
1965-07-30
Ile De France
New process for the preparation of substituted benzamides
FR1476925A
(en)
*
1965-04-08
1967-04-14
Ile De France
New process for the preparation of nu-tertiary-aminoalkyl-2-hydroxy (or alkoxy) 4-amino-5-halo benzamides
1970
1970-05-14
JP
JP45041549A
patent/JPS5024B1/ja
active
Pending
1971
1971-01-18
GB
GB224071A
patent/GB1346791A/en
not_active
Expired
1971-01-18
GB
GB4814872A
patent/GB1346792A/en
not_active
Expired
1971-01-19
BR
BR000323/71A
patent/BR7100323D0/en
unknown
1971-01-20
SE
SE7100631A
patent/SE400776B/en
unknown
1971-01-20
BE
BE761820A
patent/BE761820A/en
unknown
1971-01-20
NO
NO196/71A
patent/NO132536C/no
unknown
1971-01-20
AT
AT45271*#A
patent/AT335425B/en
not_active
IP Right Cessation
1971-01-20
AT
AT724072A
patent/AT322539B/en
not_active
IP Right Cessation
1971-01-20
FI
FI146/71A
patent/FI57098C/en
active
1971-01-20
FR
FR717101809A
patent/FR2077252B1/fr
not_active
Expired
1971-01-21
ZA
ZA710389A
patent/ZA71389B/en
unknown
1971-01-21
ES
ES387498A
patent/ES387498A1/en
not_active
Expired
1971-01-21
CH
CH89671A
patent/CH544086A/en
not_active
IP Right Cessation
1971-01-21
DE
DE2102848A
patent/DE2102848C3/en
not_active
Expired
1971-01-21
DE
DE19712119260
patent/DE2119260A1/en
active
Pending
1971-01-21
DK
DK25271AA
patent/DK136032B/en
unknown
1971-01-21
NL
NL7100795A
patent/NL7100795A/xx
not_active
Application Discontinuation
1971-10-05
JP
JP46078263A
patent/JPS507593B1/ja
active
Pending
1973
1973-08-30
SE
SE7311783A
patent/SE402911C/en
unknown
1973-08-30
SE
SE7311784A
patent/SE400553B/en
unknown
Also Published As
Publication number
Publication date
AT322539B
(en)
1975-05-26
ES387498A1
(en)
1974-01-16
SE402911C
(en)
1983-11-22
DK136032B
(en)
1977-08-01
DE2102848A1
(en)
1971-10-21
BE761820A
(en)
1971-07-01
DK136032C
(en)
1981-09-14
DE2102848C3
(en)
1983-03-10
FR2077252B1
(en)
1973-06-08
AT335425B
(en)
1977-03-10
SE400553B
(en)
1978-04-03
CH544086A
(en)
1973-11-15
NO132536C
(en)
1975-11-26
DE2102848B2
(en)
1975-11-06
JPS5024B1
(en)
1975-01-06
FR2077252A1
(en)
1971-10-22
GB1346792A
(en)
1974-02-13
JPS507593B1
(en)
1975-03-27
BR7100323D0
(en)
1973-07-19
FI57098C
(en)
1980-06-10
DE2119260A1
(en)
1972-03-30
ZA71389B
(en)
1971-10-27
NO132536B
(en)
1975-08-18
SE402911B
(en)
1978-07-24
NL7100795A
(en)
1971-07-23
FI57098B
(en)
1980-02-29
SE400776B
(en)
1978-04-10
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Legal Events
Date
Code
Title
Description
1974-07-03
PS
Patent sealed
1977-08-10
PLNP
Patent lapsed through nonpayment of renewal fees