GB1346791A

GB1346791A – Process and intermediates for preparing benzamide compounds
– Google Patents

GB1346791A – Process and intermediates for preparing benzamide compounds
– Google Patents
Process and intermediates for preparing benzamide compounds

Info

Publication number
GB1346791A

GB1346791A
GB224071A
GB224071A
GB1346791A
GB 1346791 A
GB1346791 A
GB 1346791A
GB 224071 A
GB224071 A
GB 224071A
GB 224071 A
GB224071 A
GB 224071A
GB 1346791 A
GB1346791 A
GB 1346791A
Authority
GB
United Kingdom
Prior art keywords
methyl
formula
phthalimidobenzoate
methoxy
isopropyl
Prior art date
1970-01-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB224071A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Delmar Chemicals Inc

Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-01-21
Filing date
1971-01-18
Publication date
1974-02-13

1971-01-18
Application filed by Delmar Chemicals Inc
filed
Critical
Delmar Chemicals Inc

1974-02-13
Publication of GB1346791A
publication
Critical
patent/GB1346791A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring

C07D209/44—Iso-indoles; Hydrogenated iso-indoles

C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Abstract

1346791 Phthalimides DELMAR CHEMICALS Ltd 18 Jan 1971 [21 Jan 1970] 2240/71 Heading C2C The invention comprises novel phthalimides of the Formula II wherein X is Cl or Br, and R 1 and R 2 each are H or alkyl and the conversion of the above compounds in which R 1 and R 2 are alkyl into benzamides of the Formula I wherein R is alkyl and Z is tertiary aminoalkyl, by reacting the said compounds under substantially anhydrous conditions with diamines of the formula ZNH 2 . The compounds of Formula II above are prepared by reacting the appropriate amines with phthalic anhydride, followed by or preceded by, esterification, alkylation and/or bromination or chlorination. Methyl 2-methoxy-4-phthalimidobenzoate is obtained by methylating methyl 4-phthalimidosalicylate, resulting from the reaction of phthalic anhydride on methyl 4-aminosalicylate, obtained by esterifying 4-aminosalicyclic acid. The first named compound may also be obtained by reacting dimethyl sulphate with 4-phthalimidosalicylic acid resulting from the reaction between phthalic anhydride and 4-aminosalicylic acid. Ethyl and isopropyl 4-aminosalicylate, ethyl and isopropyl 4-phthalimidosalicylate, and ethyl and isopropyl 2-methoxy-4-phthalimidobenzoate are obtained by similar processes. N – (2 – Diethylaminoethyl)phthalimide is obtained as a by-product in the reaction between N,N-diethylethylenediamine and methyl 5- chloro-2-methoxy-4-phthalimidobenzoate. Reference has been directed by the Comptroller to Specification 994,023.

GB224071A
1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds

Expired

GB1346791A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

US458770A

1970-01-21
1970-01-21

Publications (1)

Publication Number
Publication Date

GB1346791A
true

GB1346791A
(en)

1974-02-13

Family
ID=21711507
Family Applications (2)

Application Number
Title
Priority Date
Filing Date

GB224071A
Expired

GB1346791A
(en)

1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds

GB4814872A
Expired

GB1346792A
(en)

1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds

Family Applications After (1)

Application Number
Title
Priority Date
Filing Date

GB4814872A
Expired

GB1346792A
(en)

1970-01-21
1971-01-18
Process and intermediates for preparing benzamide compounds

Country Status (15)

Country
Link

JP
(2)

JPS5024B1
(en)

AT
(2)

AT335425B
(en)

BE
(1)

BE761820A
(en)

BR
(1)

BR7100323D0
(en)

CH
(1)

CH544086A
(en)

DE
(2)

DE2102848C3
(en)

DK
(1)

DK136032B
(en)

ES
(1)

ES387498A1
(en)

FI
(1)

FI57098C
(en)

FR
(1)

FR2077252B1
(en)

GB
(2)

GB1346791A
(en)

NL
(1)

NL7100795A
(en)

NO
(1)

NO132536C
(en)

SE
(3)

SE400776B
(en)

ZA
(1)

ZA71389B
(en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

JPH0825970B2
(en)

*

1987-09-01
1996-03-13
住友化学工業株式会社

Process for producing tetrahydrophthalimide compound, intermediate thereof and process for producing the intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE1233877B
(en)

*

1961-07-25
1967-02-09
Ile De France

Process for the preparation of substituted N- (tert. Aminoalkyl) -benzamides

FR1407055A
(en)

*

1963-03-05
1965-07-30
Ile De France

New process for the preparation of substituted benzamides

FR1476925A
(en)

*

1965-04-08
1967-04-14
Ile De France

New process for the preparation of nu-tertiary-aminoalkyl-2-hydroxy (or alkoxy) 4-amino-5-halo benzamides

1970

1970-05-14
JP
JP45041549A
patent/JPS5024B1/ja
active
Pending

1971

1971-01-18
GB
GB224071A
patent/GB1346791A/en
not_active
Expired

1971-01-18
GB
GB4814872A
patent/GB1346792A/en
not_active
Expired

1971-01-19
BR
BR000323/71A
patent/BR7100323D0/en
unknown

1971-01-20
SE
SE7100631A
patent/SE400776B/en
unknown

1971-01-20
BE
BE761820A
patent/BE761820A/en
unknown

1971-01-20
NO
NO196/71A
patent/NO132536C/no
unknown

1971-01-20
AT
AT45271*#A
patent/AT335425B/en
not_active
IP Right Cessation

1971-01-20
AT
AT724072A
patent/AT322539B/en
not_active
IP Right Cessation

1971-01-20
FI
FI146/71A
patent/FI57098C/en
active

1971-01-20
FR
FR717101809A
patent/FR2077252B1/fr
not_active
Expired

1971-01-21
ZA
ZA710389A
patent/ZA71389B/en
unknown

1971-01-21
ES
ES387498A
patent/ES387498A1/en
not_active
Expired

1971-01-21
CH
CH89671A
patent/CH544086A/en
not_active
IP Right Cessation

1971-01-21
DE
DE2102848A
patent/DE2102848C3/en
not_active
Expired

1971-01-21
DE
DE19712119260
patent/DE2119260A1/en
active
Pending

1971-01-21
DK
DK25271AA
patent/DK136032B/en
unknown

1971-01-21
NL
NL7100795A
patent/NL7100795A/xx
not_active
Application Discontinuation

1971-10-05
JP
JP46078263A
patent/JPS507593B1/ja
active
Pending

1973

1973-08-30
SE
SE7311783A
patent/SE402911C/en
unknown

1973-08-30
SE
SE7311784A
patent/SE400553B/en
unknown

Also Published As

Publication number
Publication date

AT322539B
(en)

1975-05-26

ES387498A1
(en)

1974-01-16

SE402911C
(en)

1983-11-22

DK136032B
(en)

1977-08-01

DE2102848A1
(en)

1971-10-21

BE761820A
(en)

1971-07-01

DK136032C
(en)

1981-09-14

DE2102848C3
(en)

1983-03-10

FR2077252B1
(en)

1973-06-08

AT335425B
(en)

1977-03-10

SE400553B
(en)

1978-04-03

CH544086A
(en)

1973-11-15

NO132536C
(en)

1975-11-26

DE2102848B2
(en)

1975-11-06

JPS5024B1
(en)

1975-01-06

FR2077252A1
(en)

1971-10-22

GB1346792A
(en)

1974-02-13

JPS507593B1
(en)

1975-03-27

BR7100323D0
(en)

1973-07-19

FI57098C
(en)

1980-06-10

DE2119260A1
(en)

1972-03-30

ZA71389B
(en)

1971-10-27

NO132536B
(en)

1975-08-18

SE402911B
(en)

1978-07-24

NL7100795A
(en)

1971-07-23

FI57098B
(en)

1980-02-29

SE400776B
(en)

1978-04-10

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(en)

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Legal Events

Date
Code
Title
Description

1974-07-03
PS
Patent sealed

1977-08-10
PLNP
Patent lapsed through nonpayment of renewal fees

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