GB1352104A – Bleomycin acid and process for the preparation thereof
– Google Patents
GB1352104A – Bleomycin acid and process for the preparation thereof
– Google Patents
Bleomycin acid and process for the preparation thereof
Info
Publication number
GB1352104A
GB1352104A
GB2272672A
GB2272672A
GB1352104A
GB 1352104 A
GB1352104 A
GB 1352104A
GB 2272672 A
GB2272672 A
GB 2272672A
GB 2272672 A
GB2272672 A
GB 2272672A
GB 1352104 A
GB1352104 A
GB 1352104A
Authority
GB
United Kingdom
Prior art keywords
acid
bleomycin
atcc
amino
bleomycinic
Prior art date
1971-05-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2272672A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-05-15
Filing date
1972-05-15
Publication date
1974-05-08
1972-05-15
Application filed by Microbial Chemistry Research Foundation
filed
Critical
Microbial Chemistry Research Foundation
1974-05-08
Publication of GB1352104A
publication
Critical
patent/GB1352104A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/8215—Microorganisms
Y10S435/822—Microorganisms using bacteria or actinomycetales
Y10S435/863—Mycobacterium
Y10S435/866—Mycobacterium smegmatis
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/8215—Microorganisms
Y10S435/822—Microorganisms using bacteria or actinomycetales
Y10S435/886—Streptomyces
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/8215—Microorganisms
Y10S435/911—Microorganisms using fungi
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/8215—Microorganisms
Y10S435/911—Microorganisms using fungi
Y10S435/929—Fusarium
Abstract
1352104 Bleomycinic acid ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI 15 May 1972 [15 May 1971] 22726/72 Heading C2A The invention comprises bleomycinic acid of Formula I Bleomycinic acid is characterized by a melting point of 228-230‹ C. (decomposition) and an elemental analysis of C: 40À80%, H: 5À29%, N: 16À45%, O: 24À78%, S: 4À53%, Cl: 3À37% and Cu: 4À78%, is soluble in water, slightly soluble in methanol, acetic acid and dimethylsulphoxide, and insoluble in ethanol, acetic acid, acetone and ether, and gives a positive result in the Pauly and Ehrlich reactions but gives a negative result in the ninhydrin, Sakaguchi, Dragendorf, Tollens, ferric chloride, Fehling and Molisch reactions, and has ultra-violet absorption maxima at 246 mÁ and 292 mÁ and has infra-red absorption bands at 3350, 1720, 1670, 1640, 1580, 1460, 1365, 1050 and 770 cm.
GB2272672A
1971-05-15
1972-05-15
Bleomycin acid and process for the preparation thereof
Expired
GB1352104A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
JP3223271A
JPS5319677B1
(en)
1971-05-15
1971-05-15
Publications (1)
Publication Number
Publication Date
GB1352104A
true
GB1352104A
(en)
1974-05-08
Family
ID=12353214
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB2272672A
Expired
GB1352104A
(en)
1971-05-15
1972-05-15
Bleomycin acid and process for the preparation thereof
Country Status (8)
Country
Link
US
(2)
US3843448A
(en)
JP
(1)
JPS5319677B1
(en)
CA
(1)
CA981609A
(en)
DE
(1)
DE2223535C3
(en)
DK
(1)
DK150075C
(en)
FR
(1)
FR2137911B1
(en)
GB
(1)
GB1352104A
(en)
NL
(1)
NL150415B
(en)
Families Citing this family (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4267102A
(en)
*
1979-03-05
1981-05-12
Nippon Kayaku Kabushiki Kaisha
Bleomycin group antibiotics
JPS58116496A
(en)
1981-12-29
1983-07-11
Nippon Kayaku Co Ltd
Amide n-substituted bleomycins
Family Cites Families (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3846400A
(en)
*
1969-02-15
1974-11-05
Microbial Chem Res Found
Novel process for producing antibiotics bleomycin
US3932374A
(en)
*
1971-05-15
1976-01-13
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
Bleomycinic acid and process for preparing thereof
1971
1971-05-15
JP
JP3223271A
patent/JPS5319677B1/ja
active
Pending
1972
1972-05-11
US
US00252252A
patent/US3843448A/en
not_active
Expired – Lifetime
1972-05-12
DK
DK238172A
patent/DK150075C/en
active
1972-05-15
FR
FR7217328A
patent/FR2137911B1/fr
not_active
Expired
1972-05-15
DE
DE2223535A
patent/DE2223535C3/en
not_active
Expired
1972-05-15
NL
NL727206513A
patent/NL150415B/en
not_active
IP Right Cessation
1972-05-15
CA
CA142,135A
patent/CA981609A/en
not_active
Expired
1972-05-15
GB
GB2272672A
patent/GB1352104A/en
not_active
Expired
1979
1979-05-24
US
US06/041,995
patent/USRE30413E/en
not_active
Expired – Lifetime
Also Published As
Publication number
Publication date
NL7206513A
(en)
1972-11-17
DE2223535B2
(en)
1974-08-15
NL150415B
(en)
1976-08-16
JPS5319677B1
(en)
1978-06-22
DE2223535C3
(en)
1975-04-03
US3843448A
(en)
1974-10-22
DK150075C
(en)
1987-12-21
FR2137911B1
(en)
1976-04-16
DK150075B
(en)
1986-12-01
AU4229672A
(en)
1973-10-11
USRE30413E
(en)
1980-10-07
FR2137911A1
(en)
1972-12-29
DE2223535A1
(en)
1972-11-30
CA981609A
(en)
1976-01-13
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Legal Events
Date
Code
Title
Description
1974-09-18
PS
Patent sealed [section 19, patents act 1949]
1989-01-05
PCNP
Patent ceased through non-payment of renewal fee
