GB1360180A - Creation of Inventions and Patents with Artificial Intelligence

GB1360180A – Anthelmintically active benzimidazole derivatives and process for preparing them
– Google Patents

GB1360180A – Anthelmintically active benzimidazole derivatives and process for preparing them
– Google Patents
Anthelmintically active benzimidazole derivatives and process for preparing them

Info

Publication number
GB1360180A

GB1360180A
GB5966672A
GB5966672A
GB1360180A
GB 1360180 A
GB1360180 A
GB 1360180A
GB 5966672 A
GB5966672 A
GB 5966672A
GB 5966672 A
GB5966672 A
GB 5966672A
GB 1360180 A
GB1360180 A
GB 1360180A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
group
preparing
dec
benzimidazole derivatives
Prior art date
1971-12-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB5966672A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-12-27
Filing date
1972-12-27
Publication date
1974-07-17

1972-12-27
Application filed by Hoechst AG, Farbwerke Hoechst AG
filed
Critical
Hoechst AG

1974-07-17
Publication of GB1360180A
publication
Critical
patent/GB1360180A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings

C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems

C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles

C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

C07D235/30—Nitrogen atoms not forming part of a nitro radical

C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Abstract

1360180 Benzimidazoles FARBWERKE HOECHST AG 27 Dec 1972 [27 Dec 1971] 59666/72 Heading C2C Novel compounds (I) in which R 1 represents an alkyl group having from 1 to 4 carbon atoms, R 2 and R 3 , which may be the same of different, each represents a hydrogen atom, a hydroxyl group, an alkoxy group having from 1 to 4 carbon atoms, a halogen atom, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms or a carbalkoxy group having from 1 to 4 carbon atoms in the alkoxy group, R 4 represents a hydrogen or chlorine atom and X represents oxygen or sulphur, are made by standard methods from diamines VII, themselves prepared from the corresponding 3- amino-4-nitro compounds. Pharmaceutical preparations possessing anthelmintic action contain (I) as active ingredient. Administration is orally or parenterally.

GB5966672A
1971-12-27
1972-12-27
Anthelmintically active benzimidazole derivatives and process for preparing them

Expired

GB1360180A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

DE2164690A

DE2164690C3
(en)

1971-12-27
1971-12-27

5-phenoxy- and 5-phenylthiobenzimidazolyl- (2) -carbamic acid methyl ester effective as anthelmintic and process for their preparation

Publications (1)

Publication Number
Publication Date

GB1360180A
true

GB1360180A
(en)

1974-07-17

Family
ID=5829297
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB5966672A
Expired

GB1360180A
(en)

1971-12-27
1972-12-27
Anthelmintically active benzimidazole derivatives and process for preparing them

Country Status (30)

Country
Link

US
(1)

US3954791A
(en)

JP
(1)

JPS5033067B2
(en)

KR
(1)

KR780000116B1
(en)

AT
(1)

AT320638B
(en)

AU
(1)

AU465226B2
(en)

BE
(1)

BE793358A
(en)

BG
(2)

BG22080A3
(en)

CA
(1)

CA1017750A
(en)

CH
(2)

CH583710A5
(en)

CS
(2)

CS173615B2
(en)

DD
(2)

DD110760A5
(en)

DE
(1)

DE2164690C3
(en)

DK
(1)

DK130293B
(en)

EG
(1)

EG11122A
(en)

ES
(1)

ES409860A1
(en)

FI
(1)

FI54299C
(en)

FR
(1)

FR2166048B1
(en)

GB
(1)

GB1360180A
(en)

HU
(1)

HU165060B
(en)

IL
(1)

IL41170A
(en)

IT
(1)

IT1043888B
(en)

KE
(1)

KE2613A
(en)

MY
(1)

MY7600092A
(en)

NL
(1)

NL153187B
(en)

NO
(1)

NO137092C
(en)

PL
(1)

PL85192B1
(en)

RO
(1)

RO71503A
(en)

SE
(1)

SE395890B
(en)

SU
(2)

SU492086A3
(en)

ZA
(1)

ZA729076B
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4299837A
(en)

1979-12-05
1981-11-10
Montedison S.P.A.
Anthelmintic benzimidazole-carbamates

Families Citing this family (29)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3965113A
(en)

1972-12-29
1976-06-22
Syntex (U.S.A.) Inc.
5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

HU169503B
(en)

1974-02-05
1976-12-28

RO64921A
(en)

1974-05-28
1979-07-15
Syntex Inc

PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE-2-CARBAMATE DERIVATIVES

DE2432631A1
(en)

1974-07-06
1976-01-22
Hoechst Ag
Alkyl 5-phenylsulphinyl-2-benzimidazolecarbamate derivs – prepd. by oxidising corresponding 5-phenylthio cpds.

DE2441201C2
(en)

1974-08-28
1986-08-07
Hoechst Ag, 6230 Frankfurt

2-Carbalkoxyamino-5 (6) -phenyl-sulfonyloxy-benzimidazoles and process for their preparation

DE2441202C2
(en)

1974-08-28
1986-05-28
Hoechst Ag, 6230 Frankfurt

2-Carbalkoxyamino-benzimidazolyl-5 (6) -sulfonic acid-phenyl ester, process for their preparation and anthelmintic compositions containing them

US4076825A
(en)

1977-06-22
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles

US4076828A
(en)

1977-02-17
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles

US4076827A
(en)

1977-04-28
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles

IT1076022B
(en)

1977-04-20
1985-04-22
Montedison Spa

ANTIELMINTIC BENZIMIDAZOLCARBAMMATES

SE443977B
(en)

1977-05-10
1986-03-17
Chinoin Gyogyszer Es Vegyeszet

PROCEDURE FOR PREPARING 5 (6) -TIO-BENZIMIDAZOLDE DERIVATIVES

US4156006A
(en)

1978-01-09
1979-05-22
E. R. Squibb & Sons, Inc.
Vinyl sulfide derivatives of benzimidazoles

US4136174A
(en)

1978-01-18
1979-01-23
E. R. Squibb & Sons, Inc.
Benzimidazolecarbamates and method

US4154846A
(en)

1978-06-16
1979-05-15
E. R. Squibb & Sons, Inc.
Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates

EP0028455A1
(en)

1979-10-12
1981-05-13
Imperial Chemical Industries Plc
5-Phenylselenobenzimidazole derivatives, their preparation and anthelmintic or fasciolicidal compositions containing them

US4662935A
(en)

1980-01-14
1987-05-05
Rohm And Haas Company
Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers

DE3260986D1
(en)

1981-03-18
1984-11-22
Ciba Geigy Ag
Anthelmintics

IE56125B1
(en)

1982-10-28
1991-04-24
Ici Plc
Indole derivatives

WO1990010630A1
(en)

1989-03-15
1990-09-20
Janssen Pharmaceutica N.V.
[5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates

NZ232785A
(en)

1989-03-15
1991-03-26
Janssen Pharmaceutica Nv
5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions

US5538989A
(en)

1993-11-10
1996-07-23
Hoechst-Roussel Agri-Vet Company
Fenbendazole formulations

US5861142A
(en)

1996-03-25
1999-01-19
Schick; Mary Pichler
Method for promoting hair, nail, and skin keratinization

GB9900752D0
(en)

1999-01-15
1999-03-03
Angiogene Pharm Ltd
Benzimidazole vascular damaging agents

US7396819B2
(en)

2003-08-08
2008-07-08
Virbac Corporation
Anthelmintic formulations

US7582612B2
(en)

2004-03-12
2009-09-01
Hartz Mountain Corporation
Multi-action anthelmintic formulations

JP5227795B2
(en)

2005-07-28
2013-07-03
インターベツト・インターナシヨナル・ベー・ベー

Novel benzimidazole (thio) carbamate with antiparasitic activity and its synthesis

EP2032046B1
(en)

2006-06-12
2015-11-04
Smith & Nephew, Inc.
Systems and devices for tibial resection

WO2007144362A1
(en)

2006-06-14
2007-12-21
Intervet International B.V.
A suspension comprising benzimidazole carbamate and a polysorbate

CA3043549A1
(en)

2015-11-30
2017-06-08
Children’s Medical Center Corporation
Compounds for treating proliferative diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US3480642A
(en)

1967-03-22
1969-11-25
Smithkline Corp
Process for producing 2-carbalkoxyaminobenzimidazoles

DK131821C
(en)

1967-03-22
1976-03-08
Smith Kline French Lab

ANALOGICAL PROCEDURE FOR THE PREPARATION OF A 2-CARBALCOXYAMINOBENZIMIDAZOLE

FR2063815A5
(en)

1969-10-31
1971-07-09
Aries Robert
Antifungal and anthelmintic benzimidazole carbamates

BE
BE793358D
patent/BE793358A/en
not_active
IP Right Cessation

1971

1971-12-27
DE
DE2164690A
patent/DE2164690C3/en
not_active
Expired

1972

1972-12-19
RO
RO7273205A
patent/RO71503A/en
unknown

1972-12-20
CS
CS8805A
patent/CS173615B2/cs
unknown

1972-12-20
CH
CH827476A
patent/CH583710A5/xx
not_active
IP Right Cessation

1972-12-20
CS
CS5893A
patent/CS173650B2/cs
unknown

1972-12-20
CH
CH1856672A
patent/CH580080A5/xx
not_active
IP Right Cessation

1972-12-20
HU
HUHO1535A
patent/HU165060B/hu
unknown

1972-12-20
ES
ES409860A
patent/ES409860A1/en
not_active
Expired

1972-12-21
DD
DD178527*A
patent/DD110760A5/xx
unknown

1972-12-21
DD
DD167796A
patent/DD109219A5/xx
unknown

1972-12-21
FI
FI3637/72A
patent/FI54299C/en
active

1972-12-22
DK
DK642872AA
patent/DK130293B/en
unknown

1972-12-22
NL
NL727217532A
patent/NL153187B/en
not_active
IP Right Cessation

1972-12-22
IT
IT33528/72A
patent/IT1043888B/en
active
Protection Beyond IP Right Term

1972-12-22
AU
AU50486/72A
patent/AU465226B2/en
not_active
Expired

1972-12-22
CA
CA159,777A
patent/CA1017750A/en
not_active
Expired

1972-12-22
NO
NO4753/72A
patent/NO137092C/en
unknown

1972-12-22
AT
AT1099672A
patent/AT320638B/en
not_active
IP Right Cessation

1972-12-23
BG
BG22217A
patent/BG22080A3/xx
unknown

1972-12-23
BG
BG25960A
patent/BG20591A3/xx
unknown

1972-12-23
PL
PL1972159809A
patent/PL85192B1/pl
unknown

1972-12-25
IL
IL41170A
patent/IL41170A/en
unknown

1972-12-26
US
US05/318,271
patent/US3954791A/en
not_active
Expired – Lifetime

1972-12-26
KR
KR7201961A
patent/KR780000116B1/en
active

1972-12-26
EG
EG541/72A
patent/EG11122A/en
active

1972-12-27
ZA
ZA729076A
patent/ZA729076B/en
unknown

1972-12-27
SU
SU1865601A
patent/SU492086A3/en
active

1972-12-27
FR
FR7246316A
patent/FR2166048B1/fr
not_active
Expired

1972-12-27
SE
SE7216998A
patent/SE395890B/en
unknown

1972-12-27
GB
GB5966672A
patent/GB1360180A/en
not_active
Expired

1972-12-27
JP
JP734324A
patent/JPS5033067B2/ja
not_active
Expired

1973

1973-11-11
SU
SU1967977A
patent/SU493967A3/en
active

1976

1976-03-22
KE
KE2613*UA
patent/KE2613A/en
unknown

1976-12-30
MY
MY92/76A
patent/MY7600092A/en
unknown

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4299837A
(en)

1979-12-05
1981-11-10
Montedison S.P.A.
Anthelmintic benzimidazole-carbamates

Also Published As

Publication number
Publication date

AT320638B
(en)

1975-02-25

ES409860A1
(en)

1975-11-16

DD109219A5
(en)

1974-10-20

ZA729076B
(en)

1973-11-28

DK130293B
(en)

1975-02-03

JPS5033067B2
(en)

1975-10-27

RO71503A
(en)

1981-01-30

SU492086A3
(en)

1975-11-15

SU493967A3
(en)

1975-11-28

FR2166048B1
(en)

1976-07-02

DE2164690C3
(en)

1981-04-16

NL153187B
(en)

1977-05-16

CH580080A5
(en)

1976-09-30

BE793358A
(en)

1973-06-27

CS173650B2
(en)

1977-02-28

KE2613A
(en)

1976-04-15

US3954791A
(en)

1976-05-04

KR780000116B1
(en)

1978-04-15

NL7217532A
(en)

1973-06-29

BG22080A3
(en)

1976-11-25

CS173615B2
(en)

1977-02-28

MY7600092A
(en)

1976-12-31

IL41170A
(en)

1977-01-31

DE2164690A1
(en)

1973-07-12

EG11122A
(en)

1977-05-31

IL41170A0
(en)

1973-02-28

HU165060B
(en)

1974-06-28

FI54299B
(en)

1978-07-31

DE2164690B2
(en)

1980-08-14

SE395890B
(en)

1977-08-29

DD110760A5
(en)

1975-01-12

JPS4880558A
(en)

1973-10-29

FR2166048A1
(en)

1973-08-10

BG20591A3
(en)

1975-12-05

DK130293C
(en)

1975-06-30

IT1043888B
(en)

1980-02-29

AU5048672A
(en)

1974-06-27

NO137092B
(en)

1977-09-19

PL85192B1
(en)

1976-04-30

FI54299C
(en)

1978-11-10

AU465226B2
(en)

1975-09-18

CH583710A5
(en)

1977-01-14

NO137092C
(en)

1977-12-28

CA1017750A
(en)

1977-09-20

Información de contacto