GB1432660A

GB1432660A – Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them
– Google Patents

GB1432660A – Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them
– Google Patents
Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

Info

Publication number
GB1432660A

GB1432660A
GB5030973A
GB5030973A
GB1432660A
GB 1432660 A
GB1432660 A
GB 1432660A
GB 5030973 A
GB5030973 A
GB 5030973A
GB 5030973 A
GB5030973 A
GB 5030973A
GB 1432660 A
GB1432660 A
GB 1432660A
Authority
GB
United Kingdom
Prior art keywords
preparation
piperazine derivatives
pharamacueitcal
compositions containing
oct
Prior art date
1973-10-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB5030973A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Science Union et Cie

Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1973-10-30
Filing date
1973-10-30
Publication date
1976-04-22

1973-10-30
Application filed by Science Union et Cie
filed
Critical
Science Union et Cie

1973-10-30
Priority to GB5030973A
priority
Critical
patent/GB1432660A/en

1974-10-07
Priority to US05/512,461
priority
patent/US3954765A/en

1974-10-22
Priority to DE19742450193
priority
patent/DE2450193A1/en

1974-10-25
Priority to CA212,265A
priority
patent/CA1034576A/en

1974-10-25
Priority to FR7435776A
priority
patent/FR2248840B1/fr

1974-10-29
Priority to SU2073853A
priority
patent/SU549084A3/en

1974-10-29
Priority to JP49124828A
priority
patent/JPS5071685A/en

1974-10-30
Priority to ES431526A
priority
patent/ES431526A1/en

1976-04-22
Publication of GB1432660A
publication
Critical
patent/GB1432660A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00

C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P25/00—Drugs for disorders of the nervous system

A61P25/04—Centrally acting analgesics, e.g. opioids

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/08—Vasodilators for multiple indications

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P9/00—Drugs for disorders of the cardiovascular system

A61P9/12—Antihypertensives

Abstract

1432660 Piperazine derivatives containing two further heterocyclic rings SCIENCE UNION ET CIE SOC FRANCAISE DE RECHERCHE MEDICALE 29 Oct 1974 [30 Oct 1973] 50309/73 Heading C2C The invention comprises compounds of formula and their acid addition salts, wherein n is 0 or 1, X is O or S, and R, R1 are each H or C 1 -C 5 alkyl. The following methods are used for their preparation the products being represented W-CH 2 -Y-Z: (a) WCH 2 Br or under reductive conditions, followed by reduction of the thus-formed ketone W-CO-Y-Z, and Therapeutic compositions having peripheral vasodilatory, anti-Parkinson, antihypertensive, analgesic, neuroleptic and C.N.S. activity comprise compounds of the above formula, and may be administered orally, parenterally or rectally.

GB5030973A
1973-10-30
1973-10-30
Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

Expired

GB1432660A
(en)

Priority Applications (8)

Application Number
Priority Date
Filing Date
Title

GB5030973A

GB1432660A
(en)

1973-10-30
1973-10-30
Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

US05/512,461

US3954765A
(en)

1973-10-30
1974-10-07
Piperazines derivatives

DE19742450193

DE2450193A1
(en)

1973-10-30
1974-10-22

PIPERAZINE DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

CA212,265A

CA1034576A
(en)

1973-10-30
1974-10-25
Processes for the preparation of new piperazine derivatives

FR7435776A

FR2248840B1
(en)

1973-10-30
1974-10-25

SU2073853A

SU549084A3
(en)

1973-10-30
1974-10-29

The method of obtaining piperazine derivatives or their salts

JP49124828A

JPS5071685A
(en)

1973-10-30
1974-10-29
Piperajinjudotai oyobi sonosanenno seizohoho

ES431526A

ES431526A1
(en)

1973-10-30
1974-10-30
Piperazines derivatives

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

GB5030973A

GB1432660A
(en)

1973-10-30
1973-10-30
Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

Publications (1)

Publication Number
Publication Date

GB1432660A
true

GB1432660A
(en)

1976-04-22

Family
ID=10455445
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB5030973A
Expired

GB1432660A
(en)

1973-10-30
1973-10-30
Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

Country Status (8)

Country
Link

US
(1)

US3954765A
(en)

JP
(1)

JPS5071685A
(en)

CA
(1)

CA1034576A
(en)

DE
(1)

DE2450193A1
(en)

ES
(1)

ES431526A1
(en)

FR
(1)

FR2248840B1
(en)

GB
(1)

GB1432660A
(en)

SU
(1)

SU549084A3
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4259490A
(en)

*

1980-06-23
1981-03-31
American Cyanamid Company
2-(Substituted amino)benz[cd]indoles

Families Citing this family (6)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB1518559A
(en)

*

1976-04-12
1978-07-19
Science Union & Cie
Naphthyl derivatives processes for their preparation an pharmaceutical compositions containing them

NZ187474A
(en)

*

1977-06-10
1981-03-16
Science Union & Cie
4-heterocyclyl-piperazine-i-carbodithioic acids and salts and pharmaceutical compositions thereof

OA06083A
(en)

*

1977-11-09
1981-06-30
Science Union & Cie Ste Franca

New disubstituted piperazines, their preparation processes and pharmaceutical compositions containing them.

JPS6051189A
(en)

*

1983-08-30
1985-03-22
Sankyo Co Ltd
Thiazolidine derivative and its preparation

DE19532311A1
(en)

*

1995-09-01
1997-03-06
Basf Ag

Benzoyl derivatives

US7919496B2
(en)

*

2004-09-20
2011-04-05
Xenon Pharmaceuticals Inc.
Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes

Family Cites Families (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

DE2037852C3
(en)

*

1970-07-30
1980-06-26
Boehringer Sohn Ingelheim

New piperazine derivatives and processes for their preparation

1973

1973-10-30
GB
GB5030973A
patent/GB1432660A/en
not_active
Expired

1974

1974-10-07
US
US05/512,461
patent/US3954765A/en
not_active
Expired – Lifetime

1974-10-22
DE
DE19742450193
patent/DE2450193A1/en
not_active
Withdrawn

1974-10-25
FR
FR7435776A
patent/FR2248840B1/fr
not_active
Expired

1974-10-25
CA
CA212,265A
patent/CA1034576A/en
not_active
Expired

1974-10-29
SU
SU2073853A
patent/SU549084A3/en
active

1974-10-29
JP
JP49124828A
patent/JPS5071685A/en
active
Granted

1974-10-30
ES
ES431526A
patent/ES431526A1/en
not_active
Expired

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4259490A
(en)

*

1980-06-23
1981-03-31
American Cyanamid Company
2-(Substituted amino)benz[cd]indoles

Also Published As

Publication number
Publication date

FR2248840B1
(en)

1977-07-08

SU549084A3
(en)

1977-02-28

US3954765A
(en)

1976-05-04

CA1034576A
(en)

1978-07-11

JPS5335955B2
(en)

1978-09-29

JPS5071685A
(en)

1975-06-13

ES431526A1
(en)

1976-09-01

DE2450193A1
(en)

1975-05-07

FR2248840A1
(en)

1975-05-23

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Legal Events

Date
Code
Title
Description

1976-09-02
PS
Patent sealed [section 19, patents act 1949]

1981-06-17
PCNP
Patent ceased through non-payment of renewal fee

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