GB1523259A – Antitumor antibiotic sporamycin
– Google Patents
GB1523259A – Antitumor antibiotic sporamycin
– Google Patents
Antitumor antibiotic sporamycin
Info
Publication number
GB1523259A
GB1523259A
GB28299/77A
GB2829977A
GB1523259A
GB 1523259 A
GB1523259 A
GB 1523259A
GB 28299/77 A
GB28299/77 A
GB 28299/77A
GB 2829977 A
GB2829977 A
GB 2829977A
GB 1523259 A
GB1523259 A
GB 1523259A
Authority
GB
United Kingdom
Prior art keywords
sporamycin
july
hydrochloric acid
absorption spectrum
reactions
Prior art date
1976-07-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28299/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1976-07-10
Filing date
1977-07-06
Publication date
1978-08-31
1977-07-06
Application filed by Kitasato Institute
filed
Critical
Kitasato Institute
1978-08-31
Publication of GB1523259A
publication
Critical
patent/GB1523259A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/00—Chemistry: molecular biology and microbiology
Y10S435/8215—Microorganisms
Y10S435/822—Microorganisms using bacteria or actinomycetales
Y10S435/907—Streptosporangium
Abstract
1523259 Sporamycin KITASATO INSTITUTE 6 July 1977 [10 July 1976] 28299/77 Heading C3H The antitumour antibiotic sporamycin having the following properties: (1) elemental analysis: carbon 44À72-47À38%; hydrogen 6À4-6À88%; nitrogen 13À9-15À0%; (2) ultraviolet absorption spectrum: absorption peaks at 285 nm. (shoulder), 276 nm,. 267 nm., 265 nm., 258 nm. and 253 nm. in an aqueous and 0À1 N hydrochloric acid solution; peak at 290 nm. in 0À1 N aqueous sodium hydroxide solution; (3) infrared absorption spectrum: absorption peaks at 3320 cm<-1>, 1640 cm.<-1> and 1520 cm.<-1> in KBr; (4) white powder; (5) solubility: soluble in water; insoluble in methanol, ethanol and acetone; (6) colour reaction: positive for Folin- Lowry, Ehrlich and biuret reactions; weakly positive for ninhydrin reaction; negative for Molisch, Fehling, Tollens and anthrone reactions; (7) molecular weight: 10,500-13,000; (8) amino acid analysis of 6N hydrochloric acid hydrolysis product (110 C.; 15 hours) : at least 12 kinds of amino acids: lysine, aspartic acid, threonine, serine, glutamic acid, glycine, alanine, valine, isoleucine, leucine, tyrosine and phenylalanine; (9) basic substance; (10 melting point: becomes brown at 220-225 C. and carbonizes with increasing temperature; and (11) [alpha]D<20>: approximately -56 (C=0À5, H2O) is claimed per se. It may be prepared by culturing Streptosporanjuim pseudovulgare in a conventional nutrient medium.
GB28299/77A
1976-07-10
1977-07-06
Antitumor antibiotic sporamycin
Expired
GB1523259A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
JP51081470A
JPS595278B2
(en)
1976-07-10
1976-07-10
New antibiotic PO-357 substance and its manufacturing method and uses
Publications (1)
Publication Number
Publication Date
GB1523259A
true
GB1523259A
(en)
1978-08-31
Family
ID=13747280
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB28299/77A
Expired
GB1523259A
(en)
1976-07-10
1977-07-06
Antitumor antibiotic sporamycin
Country Status (5)
Country
Link
US
(1)
US4147774A
(en)
JP
(1)
JPS595278B2
(en)
DE
(1)
DE2730952C2
(en)
FR
(1)
FR2357573A1
(en)
GB
(1)
GB1523259A
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US6638659B1
(en)
1999-04-30
2003-10-28
University Of Connecticut
Membrane electrode assemblies using ionic composite membranes
Families Citing this family (6)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS55102596A
(en)
*
1978-12-27
1980-08-05
Meiji Seika Kaisha Ltd
Novel antibiotic substance, bn-183b substance, and its preparation
WO1981000962A1
(en)
*
1979-10-12
1981-04-16
Boehringer Sohn Ingelheim
Antibiotic compounds,process for the preparation and pharmaceutical compositions thereof,methods of treatment therewith and staphylococcus bacteria
US4529542A
(en)
*
1983-06-21
1985-07-16
The Kitasato Institute
Novel proteinous substance KUD-PC and its production
FR2548686B1
(en)
*
1983-07-08
1987-12-04
Kitasato Inst
NOVEL KUD-PC PROTEIN, PROCESS FOR THE PREPARATION THEREOF AND ITS USE AS A MEDICINAL PRODUCT
JPH01193185A
(en)
*
1988-01-28
1989-08-03
Nitto Seiko Co Ltd
Industrial robot
EP1470241A2
(en)
*
2002-01-24
2004-10-27
Ecopia Biosciences Inc.
Method, system and knowledge repository for identifying a secondary metabolite from a microorganism
1976
1976-07-10
JP
JP51081470A
patent/JPS595278B2/en
not_active
Expired
1977
1977-07-06
GB
GB28299/77A
patent/GB1523259A/en
not_active
Expired
1977-07-08
FR
FR7721152A
patent/FR2357573A1/en
active
Granted
1977-07-08
DE
DE2730952A
patent/DE2730952C2/en
not_active
Expired
1977-07-11
US
US05/814,665
patent/US4147774A/en
not_active
Expired – Lifetime
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US6638659B1
(en)
1999-04-30
2003-10-28
University Of Connecticut
Membrane electrode assemblies using ionic composite membranes
Also Published As
Publication number
Publication date
JPS537601A
(en)
1978-01-24
FR2357573B1
(en)
1979-07-20
DE2730952A1
(en)
1978-04-20
JPS595278B2
(en)
1984-02-03
DE2730952C2
(en)
1984-12-13
US4147774A
(en)
1979-04-03
FR2357573A1
(en)
1978-02-03
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Legal Events
Date
Code
Title
Description
1979-01-24
PS
Patent sealed [section 19, patents act 1949]
1988-03-02
PCNP
Patent ceased through non-payment of renewal fee
