GB1572650A – Shielded syringe
– Google Patents
GB1572650A – Shielded syringe
– Google Patents
Shielded syringe
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Info
Publication number
GB1572650A
GB1572650A
GB11374/77A
GB1137477A
GB1572650A
GB 1572650 A
GB1572650 A
GB 1572650A
GB 11374/77 A
GB11374/77 A
GB 11374/77A
GB 1137477 A
GB1137477 A
GB 1137477A
GB 1572650 A
GB1572650 A
GB 1572650A
Authority
GB
United Kingdom
Prior art keywords
syringe
barrel
shell
shielding
radiation
Prior art date
1976-03-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB11374/77A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medi Ray Inc
Original Assignee
Medi Ray Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1976-03-19
Filing date
1977-03-17
Publication date
1980-07-30
1977-03-17
Application filed by Medi Ray Inc
filed
Critical
Medi Ray Inc
1980-07-30
Publication of GB1572650A
publication
Critical
patent/GB1572650A/en
Status
Expired
legal-status
Critical
Current
Links
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Global Dossier
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Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
A61M5/178—Syringes
A61M5/1785—Syringes comprising radioactive shield means
Description
PATENT SPECIFICATION
( 11) 1 572 650 ( 21) Application No 11374/77 ( 31) ( 33) ( 44) ( 51) ( 52) ( 72) ( 22) Filed 17 Mar 1977 ( 19) Convention Application No 668531 ( 32) Filed 19 Mar 1976 in United States of America (US)
Complete Specification Published 30 Jul 1980
INT CL 3 G 21 F 5/00 Index at Acceptance B 4 Q 13 X 14 5 A Inventors: RALPH FARELLA BARRY DANSKY LEONARD EPIFANO CARL COLLICA ( 54) SHIELDED SYRINGE ( 71) We, MEDI-RAY, INC a Corporation organised and existing under the laws of the State of New York, United States of America, of 150 Marbledale Road, Tuckahoe, New York 10707, United States of America, do hereby declare the invention, for which we pray that a patent may be granted to us and the method by which it is to be performed, to be particularly described in and by the following statement:-
This invention relates to the field of shielding radioactive materials and, more particularly, to an improved syringe shield which is partially disposable.
For various tvpes of diagnostic testing it is necessary to inject radioactive materials into a patient It is well recognised that technicians who handle these materials need protection against the perils of cumulative ionising radiation exposure so provision is commonly made for shielding the materials until such time as they are injected into the patient Toward this end, various types of syringe shields have been developed The typical prior art syringe shield includes a lead cylinder which fits over a syringe, the lead body having a window of leaded glass which allows the operator to see the scale on the syringe which is placed within the lead cylinder.
There are a number of disadvantages associated with commercially available syringe shield designs One such proble is that there is no standardisation of syringe sizes, and even syringes having the same volume often have different physical dimensions For example, a 10 cc syringe may have various possible diameters depending on the particular manufacturer Thus special provision is generally necessary to fit a syringe shield to the different possible syringe sizes For example in one prior design the syringe shield is provided with a set screw”‘ which adjustably protrudes into the syringe shield’s bore and engages the syringe so that it cannot move around within the syringe shield The use of this technique involves some inconvenience and can occasionally cause breakage of the syringe.
Disposable syringes are in widespread use and their advantages are well recognized.
Similar advantages would accrue if a disposable shielded syringe existed For example, a disposable shielded syringe would eliminate the need for medical personnel to locate an appropriately sized syringe shield and assemble the syringe shield over the syringe to be used The need to decontaminate, clean and maintain permanent syringe shields would also be eliminated However, to applicant’s knowledge no disposable shielded syringe has become commercially available One reason for this void is the cost of a shielded syringe which includes such expensive parts as a leaded glass window A further item of expense relates to the need for making shielded syringes suitable for use under hospital or laboratory sanitary conditions The presence of a heavy shielding body, typically lead, introduces problems in that an unfinished lead exterior tends to become dirty and contaminated and is unsuitable for hospital conditions Provisions for special finishing or plating generally involve expense As a result of these factors, the prospect of disposing of a syringe shield or of an integrally shielded syringe has not been commercial feasible.
A shielded syringe according to one aspect of the present invention comprises: a syringe having a barrel, a tip on the front of the barrel, and a plunger slideable in the barrel and extending from the rear of the barrel for manual actuation, said syringe having volumetric indicia disposed along its barrel: a body of radiation-shielding material substantially covering the barrel of the syringe, the body having a slot therein which is in registration with at least some of the said indicia; a shell substantially covering W) 0 I-= 1 572 650 the radiation-shielding body, the shell having a slot therein which is in registration with the slot in the said radiation-shielding body; an optically transparent radiationshielding member proportioned to generally conform in size to the slot in the said body and removably insertible therein; and retaining means adapted for engaging the shell and the transparent radiation-shielding member so as to removably retain the said member in the body.
In one embodiment of the invention the retaining means comprises a retaining sleeve proportioned to slideably fit over the shell and which extends over at least a portion of the periphery of the transparent radiationshielding member so as to retain the member while permitting the said indicia to be viewed through the said member In this embodiment the retaining sleeve has a slot which is in general registration with parallel edges of the transparent radiation-shielding member, and a pair of lipped panels extend outwardly from the parallel edges of the slot The lipped panels are proportioned such that the lips engage the upper edges of the transparent radiation-shielding member so as to retain it in place In another embodiment of the invention the radiationshielding body has a pair of lipped panels extending outwardly therefrom and the retaining means is a casing housing the transparent radiation-shielding member, the casing and the transparent member being removably slideable between the panels of the said body for temporary retention In a still further embodiment of the invention the retaining means comprises an apertured cap member mounted on a -living hinge-.
In operation the transparent radiationshielding member is reuseable and the remainder of the device, which is relatively inexpensive to manufacture, is disposable.
The transparent radiation-shielding member can also be temporarily removed in order to assav the radioactive material within the syringe without unnecessarily exposing medical personnel.
In one form of syringe embodying the invention the syringe plunger has a tip within the barrel a stem coupled to the plunger tip, and a plug of radiationshielding material mounted rearwardly of the plunger tip The plug conforms generallv in shape to the inner surface of the barrel.
The plug serves to shield an operator against radiation emitted axially from the rear of the barrel.
In order that the invention may be better understood some examples of apparatus embodying the invention will now be described with reference to the accompanying drawings in which:-Figure 1 is an elevational perspective view showing a shielded syringe in accordance with one embodiment of the invention.
Figure 2 is a cross-sectional view as taken through a section defined by arrows 2-2 of Figure 1.
Figure 3 is a cross-sectional view as taken through a section defined by arrows 3-3 of Figure 1.
Figure 4 is an elevational perspective view showing a shielded syringe in accordance with another embodiment of the invention.
Figure 5 is an exploded view of the shielded syringe of Figure 4.
Figure 6 is a cross-sectional view as taken through a section defined by arrows 6-6 of Figure 4.
Figure 7 is a cross-sectional view as taken through a section defined by arrows 7-7 of Figure 4.
Figure 8 is an elevational perspective view showing a shielded syringe in accordance with another embodiment of the invention.
Referring to Figures 1-3, there is shown a shielded syringe in accordance with an embodiment of the invention The device core includes the basic elements of a conventional disposable-type plastic syringe, as labeled in the drawings by reference numeral 10 The syringe 10 has a plastic body or barrel 11 a rear flange 12 a plunger 13 and a tip 14 The plunger 13 has a head or tip 14.
The plunger 13 has a head or tip 17 which is coupled to the plunger stem 18 by a shielding plug 19 This structure is described in detail hereinbelow in conjunction with another embodiment The syringe body has volumetric indicia disposed in a longitudinal pattern along its barrel as shown at 15 A cylindrical body 30 is formed of a high densitv radiation-shielding material, such as lead T he body 30, which is open-ended at its rear end and tapers at its front end at 31.
is proportioned such that its inner surface conforms generally to the outer surface of the syringe barrel 11 The body 30 has an elongated rectangular slot extending along one side thereof, the slot being in registration with the indicia 15 on the barrel 11 The slot in the body has a flat depression 32 formed around the periphery thereof in which an optically transparent radiationshielding member 40 is seated The member is of elongated rectangular shape and may be formed of leaded glass typically having a thickness which is substantially greater than that of the body 30 Thus, the shielding provided by the leaded glass, which is generally of less dense material than lead, will be comparable to the shielding provided by body 30 due to the greater thickness of thie leaded glass.
A cylindrical shell 50 is preferably formed of a rigid plastics material and conforms generally in shape to the outer surface of the shielding body 30 The shell 50 tapers inwardly at the front thereof (at 51) and has 1 572 650 a collar 52 which joins the tapered front of the syringe barrel 11 The shell 50 has an elongated rectangular slot which is in registration with the slot in the body 30.
A retaining sleeve 60 also preferably formed of a rigid plastics material, is generally cylindrical in shape and proportioned to slideably fit over the shell 50 from the front end of the device In the present embodiment, the sleeve 60 has a cross-section which is somewhat greater than semicircular to ensure its retention on the device It will be appreciated, however, that the sleeve could be a full cylinder The sleeve 60 has a pair of lipped panels 61 which are joined at the rear by connecting panel 62 and which extend inwardly and over the edges of the transparent shielding member 40 so as to retain the member in place The sleeve is preferably slightly tapered toward the front thereof to lightly grip the front of shell 50 so that it won’t slip off the shell.
The shielded syringe described above is well suited for use as a disposable item For example, a number of the described units, each minus the transparent shielding member 40, could be packaged together along with a single transparent shielding member When a shielded syringe is needed, a disposable unit can be taken from the package and the reuseable member 40 inserted in the particular unit by removing the sleeve 60, inserting the transparent shielding member 40, and replacing the sleeve 60 The device is then utilized in the manner of a conventional shielded syringe.
After use, the reuseable member 40 is extracted by removing the sleeve 60 and the remainder of the device can be disposed of.
A further advantage of the device is that the shielding member 40 can be removed at any time during use to assay the radioactive material in the shielded syringe This is accomplished by removing the member 40 and positioning the exposed aperture toward a detector In this manner, an assay can be performed without unnecessary exposure of personnel or inconvenience.
Referring to Figures 4-7 there is illustrated another embodiment of a shielded syringe device in accordance with the invept: ‘n.
The device includes a syring 110 having a plastic body or barrel 111, a rear flange 112, a plunger 113 and a tip 114 The plunger 113 has a conventional head or tip 117, typically formed of rubber, which is coupled to a plunger stem 118 by a novel shielding plug 119 The plug 119 is formed of a high density radiation-shielding material sucn as lead or tantalum or plated lead The plug has a cylindrical central portion which conforms generally to the inner circumference of the barrel 1 l a front retaining nub 119 A which is inserted in an aperture in the rear of tip 117, and a rear retaining nub 119 B which snaps into and seats in the front end of the plunger stem 118 The plug 119 serves to shield the operator using the device against radiation emitted axially from the rear of the barrel This radiation, which would typically and dangerously be directed toward the body of the operator, is generally not satisfactorily shielded in the prior art.
The syringe body has volumetric indicia disposed in a longitudinal pattern along its barrel as shown at 115 A generally cylindrical body 130 is formed of a radiationshielding material, such as lead, and, as in the previous embodiment, is proportioned such that its inner surface conforms generally to the outer surface of the syringe barrel 111 The body 130 tapers inwardly at its front end at 138 and has an elongated reactangular slot 138 extending along one side thereof, the slot being in registration with the indicia 115 on the barrel 111 The surface containing the slot is flat on top and a pair of panels 131 and 132, which can be formed integrally of the same radiationshielding material such as lead, are spaced slightly from the parallel edges of the slot and extend outwardly from the flat surface.
A transparent radiation-shielding member 140 is of elongated rectangular shape and may be formed of leaded glass typically having a thickness whichn is substantially greater than that of the body 130 The member 140 is encased in a rectangular casing 141 which is opened at the top and bottom thereof Pairs of lips 142 retain the member 140 within the casing 141 The top edge of the casing slants upward at the front thereof as shown at 145 so that the front end protrudes slightly above the top of the encased member 140 In the present embodiment the casing 141 is formed of material such as a rigid plastics material and the member 140 is snapped into the casing 141 for permanent retention therein and reuse in a manner to be described The casing is proportioned to slideably fit within the panels 131 and 132 of body 130 such that the transparent shielding member 140 overlays the periphery of the slot 139 in body 130.
A shell 150 is preferably formed of a rigid plastics material and is porportioned to generally conform in shape to the outer surface of the body 130 Specifically, the shell 150 has a pair of side panels 151 and 152 which cover and extend above the body panesl 131 and 132, respectively The panels 151 and 152 have lips 153 and 154, respectively, which define an elongated slot that is in registration with the slot 139 in body 130.
The front end of the shell 150 is about half opened and has an approximately semicircular wall 156 having a circular aperture 159 therein which receives the tip of the syringe The tip 114 is provided witn an annular groove 199 which is retained in aperture 1 572 650 159 A cylindrical shroud 157 extends axially from the wall 156 and protrudes slightly above the top edge of the wall The shroud 157, which may typically be formed integrally with the body, has an annular protrusion at 158.
To assembly the disposable portion of the device, the syringe 110, with its plunger in place, is inserted into the body 130 The syringe flange 2 has a wall member 112 A formed on the inner surface thereof which serves as a spacer between the rear end of the body 130 and the flange The syringe and body are then inserted into the openended rear of the shell The rear edge of the shell fits over the periphery of wall 112 A and is secured to the flange 112 by any suitable means such as an epoxy bond This assembly comprises the portion of the shielded syringe which is most suitable for disposability.
In operation the encased transparent shielding member 140 is inserted in the shell through the front opening therein and is retained from sliding out during use by the protruding portion of the shroud 157 After use the reusable encased member 140 is removed, removal being facilitated by the raised edge of the casing ( 145) which can be grasped such as by using the thumb and finger The casing also provides protection against chipping of the leaded glass As previously noted, a safe assay is readily achieved with the member 140 removed.
The encased transparent shielding member is then typically stored with the package of disposable units until the next use is required.
Figure 6 shows the manner in which a standard needle can be mounted over the syringe tip and is conveniently retained within the shroud 157 by the annular protrusion 158 This eliminates the need for screwing in the needle and facilitates more convenient operation However, it will be understood that a standard needle mounting such as a “Luer-lock” (Registered Trade Mark) mounting, can be employed in conjunction with other features of the invention.
The invention has been described with reference to particular embodiments, but it will be appreciated that variations within the scope of the invention will occur to those skilled in the art For example, in Figure 8 there is shown a further embodiment of the invention which is described, for ease of illustration, as a modification of the embodiment of Figure 1 In the embodiment of Figure 8 the plastic shell which covers the shielding body 30 (see e g Figures 2 and 3) is designated by reference numeral 50 ‘ The shell 50 ‘ has a pair of outwardly extending panels 61 ‘ and 63 ‘ A retaining “cap”, comprising a pair of elongated retaining lips 67 ‘ joined at the rear by a connecting panel 62 ‘, is coupled to the panel 61 ‘ by a “living hinge” at 64 ‘ the cap being integrally formed with the panel 61 ‘ during molding.
The underside of retaining lip 68 ‘ has a thin elongated protrusion 69 ‘ (shown in dashed line) which snaps into a thin slot in the top of panel 63 ‘ In operation, the transparent shielding member 40 can be inserted from above with the cap swung back and then retained in place A small flange 65 ‘ is provided to facilitate lifting the cap to extricate the member 40.
The present invention is particularly suitable for packaging a “unit dose” of radioactive material A precalibrated dosage would be loaded into the shielded syringe which may have, for example, a removable inexpensive shielding insert (e g formed of lead) to cover the slot during shipping The user would receive a sterile precalibrated syringe, substitute the transparent radiation-shielding member (if desired) as described above, use the shielded syringe, and then dispose of it, saving the transparent member The need for a troublesome and hazardous transfer of radioactive material from a shipping container to a syringe is thereby eliminated, thereby decreasing exposure risk Also, relatively large amounts of radio isotopes would not have to be ordered by the user to provide adequate reserves in the event of unexpectedly high usage rate.
Claims (14)
WHAT WE CLAIM IS:-
1 A shielded syringe, comprising: a syringe having a barrel, a tip on the front of the barrel, and a plunger slideable in the barrel and extending from the rear of the barrel for manual actuation, said syringe having volumetric indicia disposed along its barrel; a body of radiation-shielding material substantially covering the barrel of the syringe, the body having a slot therein which is in registration with at least some of the said indicia; a shell substantially covering the radiation-shielding body, the shell having a slot therein which is in registration with the slot in the said relation-shielding body; an optically transparent radiationshielding member proportioned to generally conform in size to the slot in the said body and removably insertible therein; and retaining means adapted for engaging the shell and the transparent radiation-shielding member so as to removably retain the said member in the body.
2 A shielded syringe as defined in claim 1, wherein the said retaining means comprises a retaining sleeve proportioned to slideably fit over the shell and extending over at least a portion of the periphery of the transparent radiation-shielding member so as to retain the said member while permitting the said indicia to be viewed through the said member.
1 572 650
3 A shielded syringe as defined by claim 2, wherein the retaining sleeve has a slot therein which is in registration with parallel edges of said transparent radiationshielding member, the retaining sleeve having a pair of lipped panels extending outwardly from the parallel edges of the slot therein.
4 A shielded syringe as defined by claim 3, wherein the outwardly extending lipped panels are proportioned such that the lips engage the upper edges of the transparent radiation-shielding member so as to retain the said member.
5 A shielded syringe as defined by claim 1, wherein the shell has a pair of lipped panels extending outwardly therefrom and wherein the transparent radiationshielding member is removably slideable within the panels for temporary retention.
6 A shielded syringe as defined by claim 1, wherein the radiation-shielding body has a pair of generally parallel panels extending outwardly therefrom to removably receive the transparent radiationshielding member.
7 A shielded syringe as defined by claim 6, wherein the shell has a pair of lipped panels extending outwardly adjacent the panels of the said body.
8 A shielded syringe as defined by claim 7 in which the retaining means is a generally rectangular casing proportioned to encase the transparent radiation-shielding member, the casing being removably slideable between the said panels of the radiation-shielding body for temporary retention.
9 A shielded syringe as defined by claim 1, W vherein the shell has a pair of panels extending outwardly therefrom and wherein the manually actuable means comprises an apertured cap member hinged on one of the panels.
A shielded syringe as defined by claim 9, wherein the shell is of a plastics material and the cap member is integrally coupled with the sand pane,l by a living hinge.
11 A shielded syringe as defined in any one of the preceding claims, wherein the plunger has a tip within the barrel, a so m coupled to the plunger tip, and a plug of radiation-shielding material mounted rearwardly of the plunger tip, the plug conforming generally in shape to the inner surface of the barrel.
12 A shielded syringe as defined by any one of the preceding claims, wherein the barrel and the shell are formed of plastics material.
13 A shielded syringe as defined in Claim 1 in which the plunger has a tip within the barrel, a stem coupled to the plunger tip, and a plug of radiation6: shielding material mounted rearwardly of the plunger tip, the plug conforming generally in shape to the inner surface of the barrel.
14 A shielded syringe, substantially as herein described with reference to Figures 1 to 3 or Figures 4 to 7 or Figure 8 of the accompanying drawings.
Agents for the Applicants, GILL, JENNINGS & EVERY, Chartered Patent Agents, 53 to 64 Chancery Lane, London WC 2 A 1 HN Printed for Her Majesty’s Stationery Office, by Croydon Printing Company Limited Croydon, Surrey, 1980.
Published by The Patent Office 25 Southampton Buildings, London, WC 2 A l AY, from which copies may be obtained.
GB11374/77A
1976-03-19
1977-03-17
Shielded syringe
Expired
GB1572650A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US05/668,531
US4056096A
(en)
1976-03-19
1976-03-19
Shielded syringe
Publications (1)
Publication Number
Publication Date
GB1572650A
true
GB1572650A
(en)
1980-07-30
Family
ID=24682687
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB11374/77A
Expired
GB1572650A
(en)
1976-03-19
1977-03-17
Shielded syringe
Country Status (7)
Country
Link
US
(1)
US4056096A
(en)
JP
(1)
JPS6054071B2
(en)
AU
(1)
AU506759B2
(en)
CA
(1)
CA1091116A
(en)
DE
(1)
DE2711946A1
(en)
FR
(1)
FR2362370A1
(en)
GB
(1)
GB1572650A
(en)
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US7692173B2
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1976-10-26
1978-05-18
Hart Ass Inc
Automatic actuator esp. for heart injection syringe – has pneumatic piston to give accurate injection period
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1976-12-06
1980-04-29
Medi-Ray, Inc.
System for transporting, storing and injecting radioisotope-containing fluids
US4307713A
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1980-02-13
1981-12-29
Thomas Jefferson University
Syringe shields and methods for using same
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*
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Thomas Jefferson University
Radioactive material loading, calibration and injection systems
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1994-03-23
日本メジフィジックス株式会社
Radioactive substance injection device
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1988-05-13
1989-11-24
JP3406661B2
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*
1993-12-06
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日本メジフィジックス株式会社
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Heraeus Kulzer Gmbh & Co Kg
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2001-04-13
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METHOD AND DEVICE FOR PREPARING RADIOPHARMACEUTICAL PRODUCTS FOR INJECTION
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Bruno Schmidt
Beta radiation shielding system
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Radiation Shielded Syringe Assembly and Uses Thereof
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2006-09-29
2011-07-12
Arrow International, Inc.
Syringe with selectable indicia of contents
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2006-10-11
2013-01-08
Trasis S.A.
Dispenser cartridge for radiopharmaceuticals
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*
2006-12-25
2007-05-17
Nihon Medi Physics Co Ltd
Method for protecting lead glass in radiation shielding injector
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2012-05-22
Institute Of Nuclear Energy Research
Automated dispenser for radiopharmaceuticals
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Onpharma, Inc.
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Radiation safety shield for a syringe
1976
1976-03-19
US
US05/668,531
patent/US4056096A/en
not_active
Expired – Lifetime
1977
1977-03-17
CA
CA274,178A
patent/CA1091116A/en
not_active
Expired
1977-03-17
GB
GB11374/77A
patent/GB1572650A/en
not_active
Expired
1977-03-17
AU
AU23329/77A
patent/AU506759B2/en
not_active
Expired
1977-03-18
FR
FR7708274A
patent/FR2362370A1/en
active
Granted
1977-03-18
JP
JP52029380A
patent/JPS6054071B2/en
not_active
Expired
1977-03-18
DE
DE19772711946
patent/DE2711946A1/en
not_active
Ceased
Cited By (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US7692173B2
(en)
2002-10-17
2010-04-06
Mallinckrodt, Inc.
Radiopharmaceutical pig
US7918010B2
(en)
2002-10-17
2011-04-05
Mallinckrodt Inc.
Method for making a radiopharmaceutical pig
US7918009B2
(en)
2002-10-17
2011-04-05
Mallinckrodt Inc.
Methods of using radiopharmaceutical pigs
US8269201B2
(en)
2002-10-17
2012-09-18
Mallinckrodt Llc
Radiopharmaceutical pig
Also Published As
Publication number
Publication date
DE2711946A1
(en)
1977-09-29
AU506759B2
(en)
1980-01-24
FR2362370B3
(en)
1980-02-29
CA1091116A
(en)
1980-12-09
FR2362370A1
(en)
1978-03-17
JPS6054071B2
(en)
1985-11-28
JPS52135594A
(en)
1977-11-12
AU2332977A
(en)
1978-09-21
US4056096A
(en)
1977-11-01
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Legal Events
Date
Code
Title
Description
1980-10-15
PS
Patent sealed [section 19, patents act 1949]
1986-11-19
PCNP
Patent ceased through non-payment of renewal fee