GB2016499A

GB2016499A – Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
– Google Patents

GB2016499A – Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them
– Google Patents
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them

Info

Publication number
GB2016499A

GB2016499A
GB7902710A
GB7902710A
GB2016499A
GB 2016499 A
GB2016499 A
GB 2016499A
GB 7902710 A
GB7902710 A
GB 7902710A
GB 7902710 A
GB7902710 A
GB 7902710A
GB 2016499 A
GB2016499 A
GB 2016499A
Authority
GB
United Kingdom
Prior art keywords
indomethacin
preparation
pharmaceutical compositions
compositions containing
inclusion complexes
Prior art date
1978-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Application number
GB7902710A
Other versions

GB2016499B
(en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Chinoin Private Co Ltd

Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-01-27
Filing date
1979-01-25
Publication date
1979-09-26

1979-01-25
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
filed
Critical
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt

1979-09-26
Publication of GB2016499A
publication
Critical
patent/GB2016499A/en

1982-07-28
Application granted
granted
Critical

1982-07-28
Publication of GB2016499B
publication
Critical
patent/GB2016499B/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

B—PERFORMING OPERATIONS; TRANSPORTING

B82—NANOTECHNOLOGY

B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES

B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K31/00—Medicinal preparations containing organic active ingredients

A61K31/33—Heterocyclic compounds

A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole

A61K31/404—Indoles, e.g. pindolol

A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES

A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient

A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit

A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes

A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring

C07D209/04—Indoles; Hydrogenated indoles

C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

C—CHEMISTRY; METALLURGY

C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON

C08B—POLYSACCHARIDES; DERIVATIVES THEREOF

C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 – C08B35/00; Derivatives thereof

C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid

C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof

C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

GB7902710A
1978-01-27
1979-01-25
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them

Expired

GB2016499B
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

HU78CI1803A

HU176215B
(en)

1978-01-27
1978-01-27
Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1

Publications (2)

Publication Number
Publication Date

GB2016499A
true

GB2016499A
(en)

1979-09-26

GB2016499B

GB2016499B
(en)

1982-07-28

Family
ID=10994689
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB7902710A
Expired

GB2016499B
(en)

1978-01-27
1979-01-25
Inclusion complexes of indomethacin their preparation and pharmaceutical compositions containing them

Country Status (23)

Country
Link

US
(1)

US4228160A
(en)

JP
(1)

JPS54117018A
(en)

AT
(1)

AT360554B
(en)

AU
(1)

AU518750B2
(en)

BE
(1)

BE873725A
(en)

CA
(1)

CA1119115A
(en)

CH
(1)

CH638819A5
(en)

CS
(1)

CS207742B2
(en)

DD
(1)

DD141312A1
(en)

DE
(1)

DE2902297A1
(en)

DK
(1)

DK154977C
(en)

ES
(1)

ES477181A1
(en)

FI
(1)

FI65441C
(en)

FR
(1)

FR2415631A1
(en)

GB
(1)

GB2016499B
(en)

HU
(1)

HU176215B
(en)

IL
(1)

IL56309A
(en)

IT
(1)

IT1118282B
(en)

NL
(1)

NL7808792A
(en)

NO
(1)

NO146637C
(en)

PL
(1)

PL117208B1
(en)

SE
(1)

SE445353B
(en)

SU
(1)

SU915807A3
(en)

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB2124489A
(en)

*

1982-07-19
1984-02-22
Ciba Geigy Ag
Medicinal composition containing pirprofen and cyclodextrin

US5079237A
(en)

*

1988-01-18
1992-01-07
Lek
Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical preparation containing the same

Families Citing this family (56)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US2606074A
(en)

*

1946-08-21
1952-08-05
Edward H Ackermann
Air distributing nozzle

US4352793A
(en)

*

1979-04-26
1982-10-05
Sumitomo Chemical Company, Limited
Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin

DE2947742C2
(en)

*

1979-11-27
1986-04-03
Koch, Jürgen, Dr., 2000 Hamburg

Medicaments containing β-cyclodextrin

HU184066B
(en)

*

1979-12-28
1984-06-28
Chinoin Gyogyszer Es Vegyeszet
Plant growth regulating substance and process for preparing such compound

HU181733B
(en)

*

1980-08-07
1983-11-28
Chinoin Gyogyszer Es Vegyeszet
Process for preparing sorbents containing cyclodextrin on cellulose base

HU182217B
(en)

*

1980-10-17
1983-12-28
Chinoin Gyogyszer Es Vegyeszet
Process for producing inclusive complexes of cyclodextrines and strong inorganic oxyacids

JPS5830032B2
(en)

*

1981-02-18
1983-06-27
呉羽化学工業株式会社

Bifidus bacteria growth agent

HU183430B
(en)

*

1981-05-12
1984-05-28
Chinoin Gyogyszer Es Vegyeszet
Process for producing cyclodextrine inclusion complexes of n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine or n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine-hydrochloride

JPS58177949A
(en)

*

1982-04-12
1983-10-18
Takeda Chem Ind Ltd
Clathrate compound of lankacidin-group antibiotic substance

US4425336A
(en)

1982-05-24
1984-01-10
Key Pharmaceuticals, Inc.
3,4-Dihydroxy-N-[3-(4-dihydroxyphenyl)-1-methyl-n-propyl]-beta-phenethylamine cyclodextrin complexes

HU190818B
(en)

*

1982-11-09
1986-11-28
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu
Process for producing complexes of piperonyl-butoxide-cyclodextrin

HU191101B
(en)

*

1983-02-14
1987-01-28
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu
Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups

US4502930A
(en)

*

1983-06-27
1985-03-05
Agency Of Industrial Science & Technology
Method for manufacture of 7-substituted quadricyclene-cyclodextrin inclusion compound

JPS6025967A
(en)

*

1983-07-21
1985-02-08
Eisai Co Ltd
Tripamide clathrate compound

US4675395A
(en)

*

1984-03-14
1987-06-23
Seiwa Technological Laboratories Limited
Cyclodextrin inclusion compound and process for its preparation

JPS60202115A
(en)

*

1984-03-27
1985-10-12
Ichiro Shibauchi
Curing agent for epoxy resin, and curing of said epoxy resin

DE3427787A1
(en)

*

1984-07-27
1986-01-30
Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz

ACTIVE SUBSTANCE COMPLEXES OF 5-METHOXY-2 ((4-METHOXY-3,5-DIMETHYL-2-PYRIDYL) METHYLSULFINYL) -1H-BENZIMIDAZOLE WITH CYCLODEXTRINES, THEIR PRODUCTION AND MEDICINAL PRODUCTS

YU43290B
(en)

*

1986-11-13
1989-06-30
Lek Tovarna Farmacevtskih
Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine

IT1204725B
(en)

*

1987-06-17
1989-03-10
Edmond Pharma Srl

DIPYRIDAMOL INCLUSION COMPLEXES WITH CYCLODESTRINE

US4885275A
(en)

*

1987-10-15
1989-12-05
Eli Lilly And Company
Vancomycin-HCL solutions and the lyophilization thereof

US5017566A
(en)

*

1987-12-30
1991-05-21
University Of Florida
Redox systems for brain-targeted drug delivery

US5002935A
(en)

*

1987-12-30
1991-03-26
University Of Florida
Improvements in redox systems for brain-targeted drug delivery

DE3809808A1
(en)

*

1988-03-23
1989-10-05
Hexal Pharma Gmbh & Co Kg

SOLIDS, ESPECIALLY FESTORAL AND RECTAL, ETOFENAMATE-CONTAINING MEDICINAL PRODUCTS

US5997856A
(en)

*

1988-10-05
1999-12-07
Chiron Corporation
Method and compositions for solubilization and stabilization of polypeptides, especially proteins

CA2013485C
(en)

*

1990-03-06
1997-04-22
John Michael Gardlik
Solid consumer product compositions containing small particle cyclodextrin complexes

US5139687A
(en)

*

1990-05-09
1992-08-18
The Proctor & Gamble Company
Non-destructive carriers for cyclodextrin complexes

US5384186A
(en)

*

1990-05-09
1995-01-24
The Proctor & Gamble Company
Non-destructive carriers for cyclodextrin complexes

US5246611A
(en)

*

1990-05-09
1993-09-21
The Procter & Gamble Company
Non-destructive carriers for cyclodextrin complexes

JPH07583B2
(en)

*

1990-11-21
1995-01-11
北海道糖業株式会社

Water-soluble pentacyclic triterpene clathrate compound, method for producing the same, and food, beverage and oral composition using the same

US5321014A
(en)

*

1991-06-28
1994-06-14
The United States Of America As Represented By The Department Of Health And Human Services
Molecular encapsulation and delivery of alkenes alkynes and long chain alkanes, to living mammalian cells

US20040014695A1
(en)

*

1992-06-19
2004-01-22
Supergen, Inc.
Pharmaceutical formulation

US5602112A
(en)

1992-06-19
1997-02-11
Supergen, Inc.
Pharmaceutical formulation

US5403828A
(en)

*

1992-08-13
1995-04-04
American Maize-Products Company
Purification of cyclodextrin complexes

JPH10500982A
(en)

*

1994-05-27
1998-01-27
ファーマーク、ネダーランド、ベスローテン、フェンノートシャップ

Pharmaceutical composition

ZA959469B
(en)

*

1994-11-15
1996-05-15
South African Druggists Ltd
Pharmaceutical composition

US5744154A
(en)

*

1995-09-06
1998-04-28
Laboratoire Chauvin S.A.
Ready-to-use indomethacin-based eye lotion

US5824668A
(en)

*

1996-11-07
1998-10-20
Supergen, Inc.
Formulation for administration of steroid compounds

US5942501A
(en)

*

1996-08-16
1999-08-24
Collaborative Laboratories, Inc.
Cyclodextrin derivative complex

US6287603B1
(en)

*

1999-09-16
2001-09-11
Nestec S.A.
Cyclodextrin flavor delivery systems

US20020176842A1
(en)

*

2001-04-09
2002-11-28
Lyn Hughes
Extended release of active ingredients

KR100473716B1
(en)

*

2002-03-27
2005-03-08
주식회사 참 존
Inclusion complex of 7-dehydrocholesterol and cyclodextrin, cosmetic compositions containing the same and method of stabilizing 7-dehydrocholeserol

WO2006137959A1
(en)

*

2005-06-13
2006-12-28
Cargill, Incorporated
Cyclodextrin inclusion complexes and methods of preparing same

CA2610471A1
(en)

*

2005-06-13
2006-12-28
Cargill, Incorporated
Cyclodextrin inclusion complexes and methods of preparing same

US20070009532A1
(en)

*

2005-07-06
2007-01-11
Branimir Sikic
Treatment of patients with cancer using a calicheamicin-antibody conjugate in combination with zosuquidar

US20070010485A1
(en)

*

2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins

US20070010487A1
(en)

*

2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins

US20070010486A1
(en)

*

2005-07-06
2007-01-11
Jeff Schwegman
Chemotherapeutic formulations of zosuquidar trihydrochloride and modified cyclodextrins

US20070010466A1
(en)

*

2005-07-06
2007-01-11
Branimir Sikic
Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer

US20090185985A1
(en)

*

2006-06-13
2009-07-23
Cargill, Incorporated
Large-particle cyclodextrin inclusion complexes and methods of preparing same

JP2010514794A
(en)

*

2006-12-27
2010-05-06
カーギル インコーポレイテッド

Cyclodextrin-encapsulated complex and method for preparing the complex

US20080283693A1
(en)

*

2007-05-15
2008-11-20
Evans Michael J F
Propulsion apparatus and system

US20110300127A1
(en)

*

2008-05-27
2011-12-08
Fujifilm Corporation
Drug-containing composition

FR2989001B1
(en)

*

2012-04-06
2017-07-21
Centre Nat Rech Scient

MICROPARTICLES AND NANOPARTICLES COMPRISING HYDROPHOBIC POLYSACCHARIDES AND ALPHA-CYCLODEXTRIN

RS62097B1
(en)

2016-02-04
2021-08-31
Czap Research And Development Llc
Controlled-release and stratified cyclodextrin inclusion complex vehicles

CN107184989B
(en)

*

2017-05-18
2020-09-08
宁夏蓝博思化学技术有限公司
Liquiritigenin-cyclodextrin or cyclodextrin derivative inclusion compound, composition, preparation method and application

CN107158403B
(en)

*

2017-05-18
2020-09-08
宁夏蓝博思化学技术有限公司
Isoliquiritigenin-cyclodextrin or cyclodextrin derivative inclusion compound, composition, preparation method and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US2959580A
(en)

*

1956-10-17
1960-11-08
Univ Minnesota
Formation of inclusion compounds

US3061444A
(en)

*

1960-10-07
1962-10-30
Gen Foods Corp
Inclusion compounds incorporating edible juice constituents

DE1620030B1
(en)

1961-03-22
1970-03-05
Merck & Co Inc

Process for the preparation of indolyl- (3) -alkanecarboxylic acids and their salts

US4054736A
(en)

*

1970-06-10
1977-10-18
Ono Pharmaceutical Co., Ltd.
Clathrate compounds of prostaglandins or their analogues with cyclodextrin

1978

1978-01-27
HU
HU78CI1803A
patent/HU176215B/en
not_active
IP Right Cessation

1978-08-25
NL
NL7808792A
patent/NL7808792A/en
not_active
Application Discontinuation

1978-12-26
IL
IL56309A
patent/IL56309A/en
not_active
IP Right Cessation

1979

1979-01-11
IT
IT67050/79A
patent/IT1118282B/en
active

1979-01-18
SE
SE7900479A
patent/SE445353B/en
not_active
IP Right Cessation

1979-01-19
CS
CS79445A
patent/CS207742B2/en
unknown

1979-01-22
DE
DE19792902297
patent/DE2902297A1/en
active
Granted

1979-01-22
FI
FI790198A
patent/FI65441C/en
not_active
IP Right Cessation

1979-01-24
FR
FR7901796A
patent/FR2415631A1/en
active
Granted

1979-01-24
US
US06/006,185
patent/US4228160A/en
not_active
Expired – Lifetime

1979-01-25
AU
AU43671/79A
patent/AU518750B2/en
not_active
Ceased

1979-01-25
DD
DD79210634A
patent/DD141312A1/en
unknown

1979-01-25
GB
GB7902710A
patent/GB2016499B/en
not_active
Expired

1979-01-25
JP
JP765679A
patent/JPS54117018A/en
active
Pending

1979-01-26
ES
ES477181A
patent/ES477181A1/en
not_active
Expired

1979-01-26
DK
DK035079A
patent/DK154977C/en
active

1979-01-26
NO
NO790261A
patent/NO146637C/en
unknown

1979-01-26
PL
PL1979213015A
patent/PL117208B1/en
unknown

1979-01-26
CA
CA000320353A
patent/CA1119115A/en
not_active
Expired

1979-01-26
AT
AT59179A
patent/AT360554B/en
not_active
IP Right Cessation

1979-01-26
CH
CH81779A
patent/CH638819A5/en
not_active
IP Right Cessation

1979-01-26
SU
SU792718201A
patent/SU915807A3/en
active

1979-01-26
BE
BE193088A
patent/BE873725A/en
not_active
IP Right Cessation

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB2124489A
(en)

*

1982-07-19
1984-02-22
Ciba Geigy Ag
Medicinal composition containing pirprofen and cyclodextrin

US5079237A
(en)

*

1988-01-18
1992-01-07
Lek
Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical preparation containing the same

Also Published As

Publication number
Publication date

DK154977C
(en)

1989-06-12

IL56309A
(en)

1981-09-13

AU4367179A
(en)

1979-08-02

BE873725A
(en)

1979-05-16

NO790261L
(en)

1979-07-30

FI65441C
(en)

1984-05-10

CA1119115A
(en)

1982-03-02

CS207742B2
(en)

1981-08-31

GB2016499B
(en)

1982-07-28

NL7808792A
(en)

1979-07-31

JPS54117018A
(en)

1979-09-11

IT7967050D0
(en)

1979-01-11

IT1118282B
(en)

1986-02-24

ES477181A1
(en)

1979-10-16

PL117208B1
(en)

1981-07-31

FR2415631A1
(en)

1979-08-24

NO146637C
(en)

1982-11-10

CH638819A5
(en)

1983-10-14

FR2415631B1
(en)

1981-12-24

DE2902297C2
(en)

1989-02-09

NO146637B
(en)

1982-08-02

SU915807A3
(en)

1982-03-23

US4228160A
(en)

1980-10-14

AU518750B2
(en)

1981-10-15

DE2902297A1
(en)

1979-08-02

FI65441B
(en)

1984-01-31

DK154977B
(en)

1989-01-16

DD141312A1
(en)

1980-04-23

FI790198A
(en)

1979-07-28

DK35079A
(en)

1979-07-28

HU176215B
(en)

1981-01-28

SE445353B
(en)

1986-06-16

PL213015A1
(en)

1979-12-17

ATA59179A
(en)

1980-06-15

SE7900479L
(en)

1979-07-28

AT360554B
(en)

1981-01-26

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Legal Events

Date
Code
Title
Description

1985-07-24
746
Register noted ‘licences of right’ (sect. 46/1977)

1994-09-21
PCNP
Patent ceased through non-payment of renewal fee

Effective date:
19940125

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