GB2021412B – Method for preparing urokinase injection
– Google Patents
GB2021412B – Method for preparing urokinase injection
– Google Patents
Method for preparing urokinase injection
Info
Publication number
GB2021412B
GB2021412B
GB7916251A
GB7916251A
GB2021412B
GB 2021412 B
GB2021412 B
GB 2021412B
GB 7916251 A
GB7916251 A
GB 7916251A
GB 7916251 A
GB7916251 A
GB 7916251A
GB 2021412 B
GB2021412 B
GB 2021412B
Authority
GB
United Kingdom
Prior art keywords
urokinase injection
preparing
preparing urokinase
injection
urokinase
Prior art date
1978-05-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7916251A
Other versions
GB2021412A
(en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1978-05-12
Filing date
1979-05-10
Publication date
1982-08-25
1979-05-10
Application filed by Sumitomo Chemical Co Ltd
filed
Critical
Sumitomo Chemical Co Ltd
1979-12-05
Publication of GB2021412A
publication
Critical
patent/GB2021412A/en
1982-08-25
Application granted
granted
Critical
1982-08-25
Publication of GB2021412B
publication
Critical
patent/GB2021412B/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
C12N9/14—Hydrolases (3)
C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
C12N9/6424—Serine endopeptidases (3.4.21)
C12N9/6456—Plasminogen activators
C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/0012—Galenical forms characterised by the site of application
A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
C—CHEMISTRY; METALLURGY
C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
C12Y—ENZYMES
C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
C12Y304/21—Serine endopeptidases (3.4.21)
C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
GB7916251A
1978-05-12
1979-05-10
Method for preparing urokinase injection
Expired
GB2021412B
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
JP5682678A
JPS54147916A
(en)
1978-05-12
1978-05-12
Preparation of urokinase injection
Publications (2)
Publication Number
Publication Date
GB2021412A
GB2021412A
(en)
1979-12-05
GB2021412B
true
GB2021412B
(en)
1982-08-25
Family
ID=13038173
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB7916251A
Expired
GB2021412B
(en)
1978-05-12
1979-05-10
Method for preparing urokinase injection
Country Status (10)
Country
Link
US
(1)
US4244943A
(en)
JP
(1)
JPS54147916A
(en)
CA
(1)
CA1115206A
(en)
CH
(1)
CH641046A5
(en)
DE
(1)
DE2917899A1
(en)
DK
(1)
DK147812B
(en)
FR
(1)
FR2425245A1
(en)
GB
(1)
GB2021412B
(en)
IT
(1)
IT7949032D0
(en)
SE
(1)
SE7904118L
(en)
Families Citing this family (21)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS5813521A
(en)
*
1981-07-16
1983-01-26
Green Cross Corp:The
Powdery pharmaceutical of myeloperoxidase
US4350659A
(en)
*
1981-07-30
1982-09-21
Corning Glass Works
Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
JPS59139323A
(en)
*
1983-01-28
1984-08-10
Green Cross Corp:The
Dried urokinase preparation
SU1128601A1
(en)
*
1983-05-10
1985-07-15
Всесоюзный кардиологический научный центр АМН СССР
Urocinase immobilized on fibrinogen
JPS6051119A
(en)
*
1983-08-30
1985-03-22
Green Cross Corp:The
Dried pharmaceutical preparation of urokinase
JPS61111684A
(en)
*
1984-11-05
1986-05-29
Terumo Corp
Preparation of purified urokinase complex
JPS61124383A
(en)
*
1984-11-16
1986-06-12
Unitika Ltd
Stabilization of immobilized fibrinolytic enzyme
EP0208785B1
(en)
*
1985-01-14
1992-12-30
Shiseido Company Limited
Fibrinophilic urokinase complex and process for its preparation
CA1336585C
(en)
*
1985-04-16
1995-08-08
Kazuo Morimoto
Method of stabilizing urokinase precursor and dry preparation containing said precursor
JPS61238732A
(en)
*
1985-04-16
1986-10-24
Green Cross Corp:The
Method of stabilizing urokinase precursor and dried preparation
NZ217844A
(en)
*
1985-10-11
1989-10-27
Sumitomo Pharma
A sustained release pharmaceutical composition containing silicone elastomer and an albumin
JP2708749B2
(en)
*
1987-08-10
1998-02-04
エーザイ株式会社
Injectable composition containing modified tPA
WO1990001334A1
(en)
*
1988-08-05
1990-02-22
Codon
Formulations for plasminogen activator using aspartate
US4980165A
(en)
*
1989-01-27
1990-12-25
Genetics Institute, Inc.
Pharmaceutical formulations of plasminogen activator proteins
JPH02268681A
(en)
*
1989-04-07
1990-11-02
Green Cross Corp:The
Stabilization of urokinase precursor and dried preparation
JPH05501855A
(en)
*
1989-05-17
1993-04-08
リサーチ、コーポレーション、テクノロジーズ、インコーポレーテッド
Methods and compositions for treating thrombosis in mammals
EP0406008B1
(en)
*
1989-06-30
1994-09-21
Ucar Carbon Technology Corporation
Graphite sheet material
EP2236617A1
(en)
*
2009-03-31
2010-10-06
Leukocare Ag
Methods of terminal sterilization of biofunctional compositions
MY160916A
(en)
*
2010-04-27
2017-03-31
Scil Tech Gmbh
Stable mia/cd-rap formulation
CN104906054B
(en)
*
2015-06-15
2017-08-25
武汉人福药业有限责任公司
A kind of freeze-dried preparation method of urokinase
CN111450052A
(en)
*
2020-04-22
2020-07-28
南京南大药业有限责任公司
Preparation method of urokinase injection
Family Cites Families (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
BE665076A
(en)
*
1963-12-23
1965-12-08
JPS5137343B2
(en)
*
1972-12-07
1976-10-15
1978
1978-05-12
JP
JP5682678A
patent/JPS54147916A/en
active
Pending
1979
1979-05-03
DE
DE19792917899
patent/DE2917899A1/en
not_active
Withdrawn
1979-05-09
US
US06/037,280
patent/US4244943A/en
not_active
Expired – Lifetime
1979-05-10
DK
DK195079AA
patent/DK147812B/en
not_active
Application Discontinuation
1979-05-10
FR
FR7911841A
patent/FR2425245A1/en
active
Granted
1979-05-10
GB
GB7916251A
patent/GB2021412B/en
not_active
Expired
1979-05-10
CH
CH438379A
patent/CH641046A5/en
not_active
IP Right Cessation
1979-05-10
SE
SE7904118A
patent/SE7904118L/en
not_active
Application Discontinuation
1979-05-11
IT
IT7949032A
patent/IT7949032D0/en
unknown
1979-05-11
CA
CA327,420A
patent/CA1115206A/en
not_active
Expired
Also Published As
Publication number
Publication date
FR2425245B1
(en)
1983-03-11
US4244943A
(en)
1981-01-13
GB2021412A
(en)
1979-12-05
DK195079A
(en)
1979-11-13
JPS54147916A
(en)
1979-11-19
DK147812B
(en)
1984-12-17
FR2425245A1
(en)
1979-12-07
IT7949032D0
(en)
1979-05-11
CH641046A5
(en)
1984-02-15
SE7904118L
(en)
1979-11-13
DE2917899A1
(en)
1979-11-22
CA1115206A
(en)
1981-12-29
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Legal Events
Date
Code
Title
Description
1986-01-29
PCNP
Patent ceased through non-payment of renewal fee
