GB1067742A – Process for the preparation of l-ornithine l-aspartate
– Google Patents
GB1067742A – Process for the preparation of l-ornithine l-aspartate
– Google Patents
Process for the preparation of l-ornithine l-aspartate
Info
Publication number
GB1067742A
GB1067742A
GB3640563A
GB3640563A
GB1067742A
GB 1067742 A
GB1067742 A
GB 1067742A
GB 3640563 A
GB3640563 A
GB 3640563A
GB 3640563 A
GB3640563 A
GB 3640563A
GB 1067742 A
GB1067742 A
GB 1067742A
Authority
GB
United Kingdom
Prior art keywords
ornithine
aspartate
solvent
volume
preparation
Prior art date
1963-09-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3640563A
Inventor
Hirofuto Marumo
Kunio Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1963-09-16
Filing date
1963-09-16
Publication date
1967-05-03
1963-09-16
Application filed by Kyowa Hakko Kogyo Co Ltd
filed
Critical
Kyowa Hakko Kogyo Co Ltd
1963-09-16
Priority to GB3640563A
priority
Critical
patent/GB1067742A/en
1967-05-03
Publication of GB1067742A
publication
Critical
patent/GB1067742A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Abstract
Crystalline L-ornithine L-aspartate monohydrate is prepared by adding to an aqueous solution of L-ornithine L-aspartate a water-miscible organic solvent which is a non-solvent for L-ornithine L-aspartate, a volume of non-solvent of at least one-fifth, based on the volume of the solution, being added initially and, after the addition of seed crystals, a further volume of at least one-fifth being added at a rate such that at least 30 hours would be required to add the same volume of non-solvent as of the original solution.
GB3640563A
1963-09-16
1963-09-16
Process for the preparation of l-ornithine l-aspartate
Expired
GB1067742A
(en)
Priority Applications (1)
Application Number
Priority Date
Filing Date
Title
GB3640563A
GB1067742A
(en)
1963-09-16
1963-09-16
Process for the preparation of l-ornithine l-aspartate
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB3640563A
GB1067742A
(en)
1963-09-16
1963-09-16
Process for the preparation of l-ornithine l-aspartate
Publications (1)
Publication Number
Publication Date
GB1067742A
true
GB1067742A
(en)
1967-05-03
Family
ID=10387837
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB3640563A
Expired
GB1067742A
(en)
1963-09-16
1963-09-16
Process for the preparation of l-ornithine l-aspartate
Country Status (1)
Country
Link
GB
(1)
GB1067742A
(en)
Cited By (11)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4447366A
(en)
*
1980-12-04
1984-05-08
Morelle Jean V
Derivatives of lysine and aspartic acid
EP0477991A1
(en)
*
1990-09-28
1992-04-01
Kyowa Hakko Kogyo Co., Ltd.
Process for producing crystals of salt of acidic amino acid and basic amino acid
US8173706B2
(en)
2009-04-03
2012-05-08
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
CN102827017A
(en)
*
2011-06-14
2012-12-19
上海励睿化学科技有限公司
Crystal form of double salt compound and preparation method thereof
US8389576B2
(en)
2004-11-26
2013-03-05
Ucl Business Plc
Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
US8946473B2
(en)
2010-10-06
2015-02-03
Ocera Therapeutics, Inc.
Methods of making L-ornithine phenyl acetate
US10039735B2
(en)
2014-11-24
2018-08-07
Ucl Business Plc
Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
US10835506B2
(en)
2015-08-18
2020-11-17
Ocera Therapeutics, Inc.
Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate
US11066352B2
(en)
2017-05-11
2021-07-20
Ocera Therapeutics, Inc.
Processes of making L-ornithine phenylacetate
US11266620B2
(en)
2009-06-08
2022-03-08
Ucl Business Ltd
Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
CN114349652A
(en)
*
2021-12-10
2022-04-15
汕头市佳禾生物科技有限公司
Preparation method of L-lysine aspartate
1963
1963-09-16
GB
GB3640563A
patent/GB1067742A/en
not_active
Expired
Cited By (24)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4447366A
(en)
*
1980-12-04
1984-05-08
Morelle Jean V
Derivatives of lysine and aspartic acid
EP0477991A1
(en)
*
1990-09-28
1992-04-01
Kyowa Hakko Kogyo Co., Ltd.
Process for producing crystals of salt of acidic amino acid and basic amino acid
US10610506B2
(en)
2004-11-26
2020-04-07
Ucl Business Ltd
Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
US9566257B2
(en)
2004-11-26
2017-02-14
Ucl Business Plc
Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
US8389576B2
(en)
2004-11-26
2013-03-05
Ucl Business Plc
Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
US9604909B2
(en)
2009-04-03
2017-03-28
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US8492439B2
(en)
2009-04-03
2013-07-23
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US8785498B2
(en)
2009-04-03
2014-07-22
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US9034925B2
(en)
2009-04-03
2015-05-19
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US10550069B2
(en)
2009-04-03
2020-02-04
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US11161802B2
(en)
2009-04-03
2021-11-02
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US10173964B2
(en)
2009-04-03
2019-01-08
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US8173706B2
(en)
2009-04-03
2012-05-08
Ocera Therapeutics, Inc.
L-ornithine phenyl acetate and methods of making thereof
US11266620B2
(en)
2009-06-08
2022-03-08
Ucl Business Ltd
Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
US8946473B2
(en)
2010-10-06
2015-02-03
Ocera Therapeutics, Inc.
Methods of making L-ornithine phenyl acetate
US9260379B2
(en)
2010-10-06
2016-02-16
Ocera Therapeutics, Inc.
Methods of making L-ornithine phenyl acetate
CN102827017B
(en)
*
2011-06-14
2014-07-02
上海励睿化学科技有限公司
Crystal form of double salt compound and preparation method thereof
CN102827017A
(en)
*
2011-06-14
2012-12-19
上海励睿化学科技有限公司
Crystal form of double salt compound and preparation method thereof
US10525029B2
(en)
2014-11-24
2020-01-07
Ucl Business Ltd
Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
US11040021B2
(en)
2014-11-24
2021-06-22
Ucl Business Ltd
Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
US10039735B2
(en)
2014-11-24
2018-08-07
Ucl Business Plc
Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
US10835506B2
(en)
2015-08-18
2020-11-17
Ocera Therapeutics, Inc.
Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate
US11066352B2
(en)
2017-05-11
2021-07-20
Ocera Therapeutics, Inc.
Processes of making L-ornithine phenylacetate
CN114349652A
(en)
*
2021-12-10
2022-04-15
汕头市佳禾生物科技有限公司
Preparation method of L-lysine aspartate
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None