GB1081796A – Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
– Google Patents
GB1081796A – Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
– Google Patents
Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
Info
Publication number
GB1081796A
GB1081796A
GB34730/65A
GB3473065A
GB1081796A
GB 1081796 A
GB1081796 A
GB 1081796A
GB 34730/65 A
GB34730/65 A
GB 34730/65A
GB 3473065 A
GB3473065 A
GB 3473065A
GB 1081796 A
GB1081796 A
GB 1081796A
Authority
GB
United Kingdom
Prior art keywords
vaccine
water
relating
mixture
pertussis
Prior art date
1965-08-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB34730/65A
Inventor
Lewis Burnell Holt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WRIGHT FLEMING INST OF MICROBI
Original Assignee
WRIGHT FLEMING INST OF MICROBI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1965-08-13
Filing date
1965-08-13
Publication date
1967-08-31
1965-08-13
Application filed by WRIGHT FLEMING INST OF MICROBI
filed
Critical
WRIGHT FLEMING INST OF MICROBI
1965-08-13
Priority to GB34730/65A
priority
Critical
patent/GB1081796A/en
1967-08-31
Publication of GB1081796A
publication
Critical
patent/GB1081796A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K39/00—Medicinal preparations containing antigens or antibodies
A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K39/00—Medicinal preparations containing antigens or antibodies
A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K39/00—Medicinal preparations containing antigens or antibodies
A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
A61K2039/55511—Organic adjuvants
A61K2039/55566—Emulsions, e.g. Freund’s adjuvant, MF59
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K39/00—Medicinal preparations containing antigens or antibodies
A61K2039/70—Multivalent vaccine
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
A single shot trivalent injectable vaccine comprises a water-in-oil emulsion of diphtheria toxoid, tetanus toxoid and pertussis vaccine adsorbed on a mineral carrier in aqueous suspension, emulsified with an equal volume of a mixture of squalane, as an oily adjuvant and mannide mono-oleate as emulsifier. The mineral carrier may be aluminium phosphate or aluminium hydroxide. Also disclosed is a quadruple vaccine of the above vaccine further mixed with a polio virus emulsion, and for comparative purposes, similar trivalent vaccine compositions wherein the oily adjuvant is 1) almond oil, 2) a paraffin hydrocarbon; and also a simple nonemulsified mixture of aqueous toxoids of diphtheria, tetanus, and pertussis.
GB34730/65A
1965-08-13
1965-08-13
Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
Expired
GB1081796A
(en)
Priority Applications (1)
Application Number
Priority Date
Filing Date
Title
GB34730/65A
GB1081796A
(en)
1965-08-13
1965-08-13
Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB34730/65A
GB1081796A
(en)
1965-08-13
1965-08-13
Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
Publications (1)
Publication Number
Publication Date
GB1081796A
true
GB1081796A
(en)
1967-08-31
Family
ID=10369262
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB34730/65A
Expired
GB1081796A
(en)
1965-08-13
1965-08-13
Improvements in or relating to oily adjuvants for water-in-oil emulsions of antigenic materials
Country Status (1)
Country
Link
GB
(1)
GB1081796A
(en)
Cited By (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB2135190A
(en)
*
1983-02-22
1984-08-30
Human Oltoanyagtermelo
Lyophilized adsorbed polyvalent vaccines
EP0187286A1
(en)
*
1984-12-20
1986-07-16
BEHRINGWERKE Aktiengesellschaft
Oil-adjuvated vaccine and its manufacturing process
USRE32393E
(en)
*
1967-09-01
1987-04-07
Kabivitrum Ab
Composition for enhancing the administration of pharmacologically active agents
1965
1965-08-13
GB
GB34730/65A
patent/GB1081796A/en
not_active
Expired
Cited By (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
USRE32393E
(en)
*
1967-09-01
1987-04-07
Kabivitrum Ab
Composition for enhancing the administration of pharmacologically active agents
GB2135190A
(en)
*
1983-02-22
1984-08-30
Human Oltoanyagtermelo
Lyophilized adsorbed polyvalent vaccines
EP0187286A1
(en)
*
1984-12-20
1986-07-16
BEHRINGWERKE Aktiengesellschaft
Oil-adjuvated vaccine and its manufacturing process
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