GB1147336A – Quinoline-3-carboxylic acid derivatives
– Google Patents
GB1147336A – Quinoline-3-carboxylic acid derivatives
– Google Patents
Quinoline-3-carboxylic acid derivatives
Info
Publication number
GB1147336A
GB1147336A
GB2509665A
GB2509665A
GB1147336A
GB 1147336 A
GB1147336 A
GB 1147336A
GB 2509665 A
GB2509665 A
GB 2509665A
GB 2509665 A
GB2509665 A
GB 2509665A
GB 1147336 A
GB1147336 A
GB 1147336A
Authority
GB
United Kingdom
Prior art keywords
carboxylic acid
quinoline
acid derivatives
june
alkoxy
Prior art date
1965-06-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2509665A
Inventor
William Oldfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1965-06-14
Filing date
1965-06-14
Publication date
1969-04-02
1965-06-14
Application filed by Lilly Industries Ltd
filed
Critical
Lilly Industries Ltd
1965-06-14
Priority to GB2509665A
priority
Critical
patent/GB1147336A/en
1969-04-02
Publication of GB1147336A
publication
Critical
patent/GB1147336A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Abstract
1,147,336. Quinoline-3-carboxylic acid derivatives. LILLY INDUSTRIES Ltd. 28 June, 1966 [14 June, 1965], No. 25096/65. Heading C2C. Novel quinoline-3-carboxylic acid derivatives of Formula I, in which ‘each of R 1 and R 2 is hydrogen, C 1 -C 8 alkyl, substituted alkyl, alkoxy, halogen, hydroxy, nitro, amino or acylamino and R is hydroxy, C 1 -C 8 alkoxy or hydrazino, are prepared by reacting a diphenylamine of Formula II with a dialkyl alkoxymethylene malonate, causing or allowing the resulting dialkyl N,N-diarylaminomethylene malonate to cyclize and optionally thereafter hydrolysing or reacting with hydrazine the cyclized product, to form the desired compound. Pharmaceutical compositions, having antiinflammatory activity and/or antibacterial activity and/or an effect on the central nervous system, comprise one of the novel compounds together with a carrier.
GB2509665A
1965-06-14
1965-06-14
Quinoline-3-carboxylic acid derivatives
Expired
GB1147336A
(en)
Priority Applications (1)
Application Number
Priority Date
Filing Date
Title
GB2509665A
GB1147336A
(en)
1965-06-14
1965-06-14
Quinoline-3-carboxylic acid derivatives
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB2509665A
GB1147336A
(en)
1965-06-14
1965-06-14
Quinoline-3-carboxylic acid derivatives
Publications (1)
Publication Number
Publication Date
GB1147336A
true
GB1147336A
(en)
1969-04-02
Family
ID=10222161
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB2509665A
Expired
GB1147336A
(en)
1965-06-14
1965-06-14
Quinoline-3-carboxylic acid derivatives
Country Status (1)
Country
Link
GB
(1)
GB1147336A
(en)
Cited By (20)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
JPS6056959A
(en)
*
1983-07-18
1985-04-02
アボツト ラボラトリ−ズ
Quinoline antifungal compound
US4528285A
(en)
*
1984-04-26
1985-07-09
Abbott Laboratories
Methylenedioxy quino-benzothiazine derivatives
US4529725A
(en)
*
1984-04-26
1985-07-16
Abbott Laboratories
1-Pyridine substituted quino-benzothiazine
US4533663A
(en)
*
1984-04-26
1985-08-06
Abbott Laboratories
Quino-benzothiazine antibacterial compounds
US4540694A
(en)
*
1984-04-26
1985-09-10
Abbott Laboratories
1-Pyridine substituted quino-benoxazines and antibacterial use
US4542133A
(en)
*
1984-04-26
1985-09-17
Abbott Laboratories
Methylenedioxy quino-benoxazine derivatives and antibacterial use
EP0181521A1
(en)
*
1984-10-19
1986-05-21
Otsuka Pharmaceutical Co., Ltd.
Antimicrobial 1-substituted Phenyl-4-oxoquinoline-3-carboxylic acid compounds
FR2576305A1
(en)
*
1985-01-23
1986-07-25
Toyama Chemical Co Ltd
NOVEL PROCESS FOR THE MANUFACTURE OF A (SUBSTITUTED) ARYL DERIVATIVE -1 DIHYDRO-1,4-OXO-4-NAPHTHYRIDINE, INTERMEDIATE SUBSTANCES USED FOR THIS MANUFACTURE AND METHODS OF MAKING THE INTERMEDIATE SUBSTANCES
US4607032A
(en)
*
1984-04-26
1986-08-19
Abbott Laboratories
Quino-benoxazine antibacterial compounds
US4617308A
(en)
*
1985-01-25
1986-10-14
Warner-Lambert Company
7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents
US4684648A
(en)
*
1985-05-10
1987-08-04
Otsuka Pharmaceutical Company Limited
Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof
US4687770A
(en)
*
1985-12-23
1987-08-18
Abbott Laboratories
Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
US4689325A
(en)
*
1985-12-23
1987-08-25
Abbott Laboratories
Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
US4730000A
(en)
*
1984-04-09
1988-03-08
Abbott Laboratories
Quinoline antibacterial compounds
US4755513A
(en)
*
1985-01-30
1988-07-05
Otsuka Pharmaceutical Company, Limited
Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds
US4774246A
(en)
*
1984-01-26
1988-09-27
Abbott Laboratories
Quinoline antibacterial compounds
EP0131839B1
(en)
*
1983-07-18
1989-02-01
Abbott Laboratories
Quinoline antibacterial compounds
US4851535A
(en)
*
1985-01-23
1989-07-25
Toyama Chemical Co., Ltd.
Nicotinic acid derivatives
EP0154780B1
(en)
*
1984-01-26
1990-04-11
Abbott Laboratories
Quinoline antibacterial compounds
AT392791B
(en)
*
1985-01-23
1991-06-10
Toyama Chemical Co Ltd
Process for the preparation of 1-substituted aryl-1,4- dihydro-4-oxonaphthyridine derivatives
1965
1965-06-14
GB
GB2509665A
patent/GB1147336A/en
not_active
Expired
Cited By (23)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
EP0131839B1
(en)
*
1983-07-18
1989-02-01
Abbott Laboratories
Quinoline antibacterial compounds
JPS6056959A
(en)
*
1983-07-18
1985-04-02
アボツト ラボラトリ−ズ
Quinoline antifungal compound
JPH0146512B2
(en)
*
1983-07-18
1989-10-09
Abbott Lab
EP0154780B1
(en)
*
1984-01-26
1990-04-11
Abbott Laboratories
Quinoline antibacterial compounds
US4774246A
(en)
*
1984-01-26
1988-09-27
Abbott Laboratories
Quinoline antibacterial compounds
US4730000A
(en)
*
1984-04-09
1988-03-08
Abbott Laboratories
Quinoline antibacterial compounds
US4540694A
(en)
*
1984-04-26
1985-09-10
Abbott Laboratories
1-Pyridine substituted quino-benoxazines and antibacterial use
US4607032A
(en)
*
1984-04-26
1986-08-19
Abbott Laboratories
Quino-benoxazine antibacterial compounds
US4542133A
(en)
*
1984-04-26
1985-09-17
Abbott Laboratories
Methylenedioxy quino-benoxazine derivatives and antibacterial use
US4533663A
(en)
*
1984-04-26
1985-08-06
Abbott Laboratories
Quino-benzothiazine antibacterial compounds
US4529725A
(en)
*
1984-04-26
1985-07-16
Abbott Laboratories
1-Pyridine substituted quino-benzothiazine
US4528285A
(en)
*
1984-04-26
1985-07-09
Abbott Laboratories
Methylenedioxy quino-benzothiazine derivatives
EP0181521A1
(en)
*
1984-10-19
1986-05-21
Otsuka Pharmaceutical Co., Ltd.
Antimicrobial 1-substituted Phenyl-4-oxoquinoline-3-carboxylic acid compounds
FR2576305A1
(en)
*
1985-01-23
1986-07-25
Toyama Chemical Co Ltd
NOVEL PROCESS FOR THE MANUFACTURE OF A (SUBSTITUTED) ARYL DERIVATIVE -1 DIHYDRO-1,4-OXO-4-NAPHTHYRIDINE, INTERMEDIATE SUBSTANCES USED FOR THIS MANUFACTURE AND METHODS OF MAKING THE INTERMEDIATE SUBSTANCES
AT392789B
(en)
*
1985-01-23
1991-06-10
Toyama Chemical Co Ltd
METHOD FOR PRODUCING 1-SUBSTITUTED ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINE DERIVATIVES
AT392791B
(en)
*
1985-01-23
1991-06-10
Toyama Chemical Co Ltd
Process for the preparation of 1-substituted aryl-1,4- dihydro-4-oxonaphthyridine derivatives
US4704459A
(en)
*
1985-01-23
1987-11-03
Toyama Chemical Co., Ltd.
Process for producing 1-substituted aryl-1,4-dihydro-4-oxonaphthyridine derivatives, and processes for producing the intermediates
US4851535A
(en)
*
1985-01-23
1989-07-25
Toyama Chemical Co., Ltd.
Nicotinic acid derivatives
US4617308A
(en)
*
1985-01-25
1986-10-14
Warner-Lambert Company
7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents
US4755513A
(en)
*
1985-01-30
1988-07-05
Otsuka Pharmaceutical Company, Limited
Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds
US4684648A
(en)
*
1985-05-10
1987-08-04
Otsuka Pharmaceutical Company Limited
Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof
US4689325A
(en)
*
1985-12-23
1987-08-25
Abbott Laboratories
Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
US4687770A
(en)
*
1985-12-23
1987-08-18
Abbott Laboratories
Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
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