GB1237194A

GB1237194A – Pharmaceutical compositions containing 2-arylthiazoles
– Google Patents

GB1237194A – Pharmaceutical compositions containing 2-arylthiazoles
– Google Patents
Pharmaceutical compositions containing 2-arylthiazoles

Info

Publication number
GB1237194A

GB1237194A
GB48640/67A
GB4864067A
GB1237194A
GB 1237194 A
GB1237194 A
GB 1237194A
GB 48640/67 A
GB48640/67 A
GB 48640/67A
GB 4864067 A
GB4864067 A
GB 4864067A
GB 1237194 A
GB1237194 A
GB 1237194A
Authority
GB
United Kingdom
Prior art keywords
radical
cooh
amide
salt
formula
Prior art date
1967-10-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB48640/67A
Inventor
Kevan Brown
John Frederick Cavalla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

John Wyeth and Brother Ltd

Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1967-10-26
Filing date
1967-10-26
Publication date
1971-06-30

1967-10-26
Application filed by John Wyeth and Brother Ltd
filed
Critical
John Wyeth and Brother Ltd

1967-10-26
Priority to GB48640/67A
priority
Critical
patent/GB1237194A/en

1968-10-05
Priority to CA031766A
priority
patent/CA930740A/en

1968-10-07
Priority to JP7251268A
priority
patent/JPS4810466B1/ja

1968-10-11
Priority to IE121768A
priority
patent/IE32443B1/en

1968-10-14
Priority to BE722290D
priority
patent/BE722290A/xx

1968-10-15
Priority to FR1587945D
priority
patent/FR1587945A/fr

1968-10-15
Priority to FR169961A
priority
patent/FR7971M/fr

1968-10-17
Priority to CH1832872A
priority
patent/CH609051A5/en

1968-10-17
Priority to CH1556768A
priority
patent/CH540280A/en

1968-10-22
Priority to DE19681804448
priority
patent/DE1804448C3/en

1968-10-24
Priority to NL6815215A
priority
patent/NL165932C/en

1971-06-30
Publication of GB1237194A
publication
Critical
patent/GB1237194A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings

C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Novel thiazoles which have an antiinflammatory effect and which can be used as pharmaceuticals and correspond to the formula (I) in which R1 is an optionally substituted carbocyclic or heterocyclic aromatic radical; R2 is a radical of the formula -CH=CH-COOH or -CH2-CH2-COOH or the radical of a salt or amide of these acids; and R3 is hydrogen or an alkyl radical with 1 to 4 carbon atoms, and their acid addition salts, with the proviso that R2 is the radical of a salt or amide of the said acid groups if R1 is an unsubstituted phenyl radical or a mono- or dimethoxyphenyl radical and R3 is a hydrogen atom, are obtained by hydrolysing the corresponding cyanoethenyl or cyanoethyl derivatives.

GB48640/67A
1967-10-26
1967-10-26
Pharmaceutical compositions containing 2-arylthiazoles

Expired

GB1237194A
(en)

Priority Applications (11)

Application Number
Priority Date
Filing Date
Title

GB48640/67A

GB1237194A
(en)

1967-10-26
1967-10-26
Pharmaceutical compositions containing 2-arylthiazoles

CA031766A

CA930740A
(en)

1967-10-26
1968-10-05
Process for preparing mono aryl thiazole-propionic and acrylic acids and derivatives thereof

JP7251268A

JPS4810466B1
(en)

1967-10-26
1968-10-07

IE121768A

IE32443B1
(en)

1967-10-26
1968-10-11
Pharmaceutical compositions containing 2-aryl thiazoles

BE722290D

BE722290A
(en)

1967-10-26
1968-10-14

FR1587945D

FR1587945A
(en)

1967-10-26
1968-10-15

FR169961A

FR7971M
(en)

1967-10-26
1968-10-15

CH1832872A

CH609051A5
(en)

1967-10-26
1968-10-17
Process for the preparation of novel thiazoles

CH1556768A

CH540280A
(en)

1967-10-26
1968-10-17

Process for the production of new thiazoles

DE19681804448

DE1804448C3
(en)

1967-10-26
1968-10-22

β- (2-p-chlorophenyl-thiazol-4-yl) acrylic acid, pharmaceutically acceptable salts thereof and processes for making the compound

NL6815215A

NL165932C
(en)

1967-10-26
1968-10-24

METHOD FOR PREPARING AN ANTI-INFLAMMATORY ACTIVE PHARMACEUTICAL PREPARATION, AND METHOD FOR PREPARING A 2-ARYLTHIAZOL-4-YL DERIVATIVE OF AN ALIPHATIC CARBONIC ACID

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

GB48640/67A

GB1237194A
(en)

1967-10-26
1967-10-26
Pharmaceutical compositions containing 2-arylthiazoles

Publications (1)

Publication Number
Publication Date

GB1237194A
true

GB1237194A
(en)

1971-06-30

Family
ID=10449369
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB48640/67A
Expired

GB1237194A
(en)

1967-10-26
1967-10-26
Pharmaceutical compositions containing 2-arylthiazoles

Country Status (9)

Country
Link

JP
(1)

JPS4810466B1
(en)

BE
(1)

BE722290A
(en)

CA
(1)

CA930740A
(en)

CH
(2)

CH609051A5
(en)

DE
(1)

DE1804448C3
(en)

FR
(2)

FR1587945A
(en)

GB
(1)

GB1237194A
(en)

IE
(1)

IE32443B1
(en)

NL
(1)

NL165932C
(en)

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4934947A
(en)

*

1987-10-30
1990-06-19
Amp Incorporated
Modular jack for flat flexible cable

US8304438B2
(en)

2006-12-20
2012-11-06
Sanofi
Heteroarylacrylamides and their use as pharmaceuticals

Families Citing this family (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

EP1939181A1
(en)

*

2006-12-27
2008-07-02
sanofi-aventis
Heteroaryl-substituted carboxamides and use thereof for the stimulation of the expression of NO synthase

Family Cites Families (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

NL130759C
(en)

*

1965-10-07

1967

1967-10-26
GB
GB48640/67A
patent/GB1237194A/en
not_active
Expired

1968

1968-10-05
CA
CA031766A
patent/CA930740A/en
not_active
Expired

1968-10-07
JP
JP7251268A
patent/JPS4810466B1/ja
active
Pending

1968-10-11
IE
IE121768A
patent/IE32443B1/en
unknown

1968-10-14
BE
BE722290D
patent/BE722290A/xx
not_active
IP Right Cessation

1968-10-15
FR
FR1587945D
patent/FR1587945A/fr
not_active
Expired

1968-10-15
FR
FR169961A
patent/FR7971M/fr
not_active
Expired

1968-10-17
CH
CH1832872A
patent/CH609051A5/en
not_active
IP Right Cessation

1968-10-17
CH
CH1556768A
patent/CH540280A/en
not_active
IP Right Cessation

1968-10-22
DE
DE19681804448
patent/DE1804448C3/en
not_active
Expired

1968-10-24
NL
NL6815215A
patent/NL165932C/en
not_active
IP Right Cessation

Cited By (2)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4934947A
(en)

*

1987-10-30
1990-06-19
Amp Incorporated
Modular jack for flat flexible cable

US8304438B2
(en)

2006-12-20
2012-11-06
Sanofi
Heteroarylacrylamides and their use as pharmaceuticals

Also Published As

Publication number
Publication date

FR1587945A
(en)

1970-04-03

IE32443B1
(en)

1973-08-08

DE1804448C3
(en)

1981-04-02

NL165932C
(en)

1981-06-15

FR7971M
(en)

1970-06-01

CH609051A5
(en)

1979-02-15

NL165932B
(en)

1981-01-15

DE1804448A1
(en)

1969-08-14

CA930740A
(en)

1973-07-24

NL6815215A
(en)

1969-04-29

DE1804448B2
(en)

1980-07-03

IE32443L
(en)

1969-04-26

JPS4810466B1
(en)

1973-04-03

BE722290A
(en)

1969-04-14

CH540280A
(en)

1973-08-15

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