GB1268894A – Substituted cinnamamides and compositions containing them
– Google Patents
GB1268894A – Substituted cinnamamides and compositions containing them
– Google Patents
Substituted cinnamamides and compositions containing them
Info
Publication number
GB1268894A
GB1268894A
GB05749/70A
GB1574970A
GB1268894A
GB 1268894 A
GB1268894 A
GB 1268894A
GB 05749/70 A
GB05749/70 A
GB 05749/70A
GB 1574970 A
GB1574970 A
GB 1574970A
GB 1268894 A
GB1268894 A
GB 1268894A
Authority
GB
United Kingdom
Prior art keywords
alkyl
hydroxyalkyl
different
same
oconh
Prior art date
1969-04-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB05749/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1969-04-02
Filing date
1970-04-02
Publication date
1972-03-29
1970-04-02
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique
filed
Critical
LIPHA SAS
1972-03-29
Publication of GB1268894A
publication
Critical
patent/GB1268894A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/16—Amides, e.g. hydroxamic acids
A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C233/00—Carboxylic acid amides
C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Abstract
1,268,894. Compositions comprising cinnamamide derivatives. LIPHA LYONNAISE INDUSTRIELLE PHARMACEUTIQUE. 2 April, 1970 [2 April, 1969], No. 15749/70. Heading A5B. [Also in Division C2] Pharmaceutical compositions, having muscle relaxant activity and suitable for oral, parenteral or retcal administration contain cinhamamide derivatives of the forumla I in which R 1 and R 3 , which may be the same or different, are each H, C 1-4 alkyl or C 1-4 alkoxy; R 2 is H, halogen, C 1-4 alkyl or C 1-4 alkoxy; R 4 and R 5 , which may be the same or different, each are H or C 1-4 alkyl, R 6 is H, C 1-4 alkyl, C 1-4 hydroxyalkyl, aryl, or C 1-4 alkyl NH CO.O.C 2 H 4 ; R, and R 8 , which may be the same or different are each H, or C 1-4 alkyl or C 1-4 hydroxy alkyl, R 9 is H, C 1-4 alkyl or C 1-4 hydroxyalkyl and R 10 is halogen, OH, C 1-4 hydroxyalkyl, OCONH 2 , OCONHC 1-4 alkyl or OCONH-aryl, with the proviso that when R 1 , R 2 and R 3 are each OCH 3 , R 4 is CH 3 and R 5 to R 9 are H, then R 10 is not OH, in association with pharmaceutical carriers.
GB05749/70A
1969-04-02
1970-04-02
Substituted cinnamamides and compositions containing them
Expired
GB1268894A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
FR6910054A
FR2040181A1
(en)
1969-04-02
1969-04-02
Publications (1)
Publication Number
Publication Date
GB1268894A
true
GB1268894A
(en)
1972-03-29
Family
ID=9031796
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB05749/70A
Expired
GB1268894A
(en)
1969-04-02
1970-04-02
Substituted cinnamamides and compositions containing them
Country Status (19)
Country
Link
US
(2)
US3659014A
(en)
JP
(1)
JPS548666B1
(en)
BE
(1)
BE748214A
(en)
CA
(1)
CA969193A
(en)
CH
(2)
CH527167A
(en)
CS
(1)
CS154659B2
(en)
DE
(1)
DE2015447C3
(en)
DK
(1)
DK136244B
(en)
ES
(1)
ES378019A1
(en)
FI
(1)
FI53212C
(en)
FR
(1)
FR2040181A1
(en)
GB
(1)
GB1268894A
(en)
HU
(1)
HU162997B
(en)
IT
(1)
IT1043806B
(en)
NL
(1)
NL167416C
(en)
NO
(1)
NO129629B
(en)
SE
(1)
SE390020B
(en)
YU
(1)
YU34117B
(en)
ZA
(1)
ZA702130B
(en)
Families Citing this family (19)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
IT1060551B
(en)
*
1974-06-10
1982-08-20
Lorenzini Sas Inst Biochim
SUBSTITUTED AMID STARS OF 3-METHYL 4-PENYL 3 BUTENOIC ACID HAVING HIGH LIPOLIPEMIZING ACTION
US4091112A
(en)
*
1974-08-09
1978-05-23
Burroughs Wellcome Co.
Biologically active amides
GB1519762A
(en)
*
1974-08-09
1978-08-02
Wellcome Found
Cinnamamides their preparation and pharmaceutical compositions containing them
CH604705A5
(en)
*
1974-09-24
1978-09-15
Hoffmann La Roche
US4190674A
(en)
*
1976-02-03
1980-02-26
Burroughs Wellcome Co.
3-Fluoro-N-cyclopropylcinnamide
US4107320A
(en)
*
1976-08-06
1978-08-15
Burroughs Wellcome Co.
Biologically active amides
FR2544311A2
(en)
*
1983-04-14
1984-10-19
Lipha
Medicinal form of theophylline having prolonged action
FR2526317A1
(en)
*
1982-05-04
1983-11-10
Lipha
Theophylline and cinnamamide association for asthma – gives prolonged activity, up to 24 hours, and uses some novel cpds. e.g. 3-cinnamoyl 2,2-di:methyl oxazolidine
DE3361275D1
(en)
*
1982-05-04
1986-01-02
Lipha
Sustained-release theophyllin drug formulation
FR2579461B1
(en)
*
1985-03-28
1988-08-26
Strasbourg Universite L Pasteu
AMIDES OF PARA-METHOXYCINNAMIC ACID AND UROCANIC ACID FOR USE AS SOLAR FILTERS; PROCESSES FOR OBTAINING, DERMO-PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM AND APPLICATIONS
JPS62205052A
(en)
*
1986-03-05
1987-09-09
Terumo Corp
Nitric acid ester derivative and vasodilator containing same
US4876084A
(en)
*
1986-08-04
1989-10-24
Kao Corporation
P-hydroxycinnamamide derivatives and melanin inhibitor comprising the same
US5116877A
(en)
*
1989-02-02
1992-05-26
Taisho Pharmaceutical Co., Ltd.
Pharmaceutical use for cinnamamide derivatives
EP0773982B2
(en)
*
1994-07-26
2005-03-23
The Procter & Gamble Company
Rinse added fabric softener compositions containing antioxidants for sun-fade protection for fabrics
US5474691A
(en)
*
1994-07-26
1995-12-12
The Procter & Gamble Company
Dryer-added fabric treatment article of manufacture containing antioxidant and sunscreen compounds for sun fade protection of fabrics
FR2862538B1
(en)
*
2003-11-21
2006-03-03
Galderma Res & Dev
USE OF IDROCILAMIDE FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ROSACEA
WO2009031202A1
(en)
*
2007-09-04
2009-03-12
Shiseido Company Ltd.
Cinnamic acid derivatives and use thereof as ultraviolet absorber
PL220733B1
(en)
*
2012-11-07
2015-12-31
Univ Jagielloński
New alkanolamides cinnamic acid derivatives and the use of cinnamic acid derivatives alkanolamides the preparation of medicaments
CN111533693A
(en)
*
2020-05-08
2020-08-14
张建蒙
Cinnamic acid amide diazole derivative and application thereof in antifungal drugs
1969
1969-04-02
FR
FR6910054A
patent/FR2040181A1/fr
active
Pending
1970
1970-03-20
SE
SE7003817A
patent/SE390020B/en
unknown
1970-03-20
FI
FI805/70A
patent/FI53212C/fi
active
1970-03-20
DK
DK141570AA
patent/DK136244B/en
unknown
1970-03-20
NO
NO01063/70A
patent/NO129629B/no
unknown
1970-03-26
CH
CH515972A
patent/CH527167A/en
not_active
IP Right Cessation
1970-03-26
CH
CH465770A
patent/CH525189A/en
not_active
IP Right Cessation
1970-03-27
IT
IT22628/70A
patent/IT1043806B/en
active
1970-03-28
ES
ES378019A
patent/ES378019A1/en
not_active
Expired
1970-03-31
ZA
ZA702130A
patent/ZA702130B/en
unknown
1970-03-31
BE
BE748214D
patent/BE748214A/en
not_active
IP Right Cessation
1970-03-31
YU
YU839/70A
patent/YU34117B/en
unknown
1970-03-31
CS
CS212470A
patent/CS154659B2/cs
unknown
1970-03-31
US
US24359A
patent/US3659014A/en
not_active
Expired – Lifetime
1970-04-01
DE
DE2015447A
patent/DE2015447C3/en
not_active
Expired
1970-04-01
CA
CA078,926A
patent/CA969193A/en
not_active
Expired
1970-04-01
NL
NL7004638.A
patent/NL167416C/en
not_active
IP Right Cessation
1970-04-02
JP
JP2750170A
patent/JPS548666B1/ja
active
Pending
1970-04-02
GB
GB05749/70A
patent/GB1268894A/en
not_active
Expired
1970-04-02
HU
HULI207A
patent/HU162997B/hu
unknown
1971
1971-09-10
US
US00179572A
patent/US3780102A/en
not_active
Expired – Lifetime
Also Published As
Publication number
Publication date
US3780102A
(en)
1973-12-18
CS154659B2
(en)
1974-04-30
CH525189A
(en)
1972-07-15
YU34117B
(en)
1978-12-31
HU162997B
(en)
1973-05-28
NL7004638A
(en)
1970-10-06
FI53212C
(en)
1978-03-10
FR2040181A1
(en)
1971-01-22
ES378019A1
(en)
1972-05-16
NL167416C
(en)
1981-12-16
DE2015447B2
(en)
1979-07-26
SE390020B
(en)
1976-11-29
DE2015447A1
(en)
1970-10-15
NO129629B
(en)
1974-05-06
DE2015447C3
(en)
1980-04-03
BE748214A
(en)
1970-09-30
NL167416B
(en)
1981-07-16
CH527167A
(en)
1972-08-31
DK136244B
(en)
1977-09-12
YU83970A
(en)
1978-05-15
ZA702130B
(en)
1971-01-27
US3659014A
(en)
1972-04-25
CA969193A
(en)
1975-06-10
IT1043806B
(en)
1980-02-29
JPS548666B1
(en)
1979-04-17
FI53212B
(en)
1977-11-30
DK136244C
(en)
1978-03-28
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