GB1360180A – Anthelmintically active benzimidazole derivatives and process for preparing them
– Google Patents
GB1360180A – Anthelmintically active benzimidazole derivatives and process for preparing them
– Google Patents
Anthelmintically active benzimidazole derivatives and process for preparing them
Info
Publication number
GB1360180A
GB1360180A
GB5966672A
GB5966672A
GB1360180A
GB 1360180 A
GB1360180 A
GB 1360180A
GB 5966672 A
GB5966672 A
GB 5966672A
GB 5966672 A
GB5966672 A
GB 5966672A
GB 1360180 A
GB1360180 A
GB 1360180A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
group
preparing
dec
benzimidazole derivatives
Prior art date
1971-12-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5966672A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-12-27
Filing date
1972-12-27
Publication date
1974-07-17
1972-12-27
Application filed by Hoechst AG, Farbwerke Hoechst AG
filed
Critical
Hoechst AG
1974-07-17
Publication of GB1360180A
publication
Critical
patent/GB1360180A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
C07D235/30—Nitrogen atoms not forming part of a nitro radical
C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Abstract
1360180 Benzimidazoles FARBWERKE HOECHST AG 27 Dec 1972 [27 Dec 1971] 59666/72 Heading C2C Novel compounds (I) in which R 1 represents an alkyl group having from 1 to 4 carbon atoms, R 2 and R 3 , which may be the same of different, each represents a hydrogen atom, a hydroxyl group, an alkoxy group having from 1 to 4 carbon atoms, a halogen atom, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms or a carbalkoxy group having from 1 to 4 carbon atoms in the alkoxy group, R 4 represents a hydrogen or chlorine atom and X represents oxygen or sulphur, are made by standard methods from diamines VII, themselves prepared from the corresponding 3- amino-4-nitro compounds. Pharmaceutical preparations possessing anthelmintic action contain (I) as active ingredient. Administration is orally or parenterally.
GB5966672A
1971-12-27
1972-12-27
Anthelmintically active benzimidazole derivatives and process for preparing them
Expired
GB1360180A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
DE2164690A
DE2164690C3
(en)
1971-12-27
1971-12-27
5-phenoxy- and 5-phenylthiobenzimidazolyl- (2) -carbamic acid methyl ester effective as anthelmintic and process for their preparation
Publications (1)
Publication Number
Publication Date
GB1360180A
true
GB1360180A
(en)
1974-07-17
Family
ID=5829297
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB5966672A
Expired
GB1360180A
(en)
1971-12-27
1972-12-27
Anthelmintically active benzimidazole derivatives and process for preparing them
Country Status (30)
Country
Link
US
(1)
US3954791A
(en)
JP
(1)
JPS5033067B2
(en)
KR
(1)
KR780000116B1
(en)
AT
(1)
AT320638B
(en)
AU
(1)
AU465226B2
(en)
BE
(1)
BE793358A
(en)
BG
(2)
BG22080A3
(en)
CA
(1)
CA1017750A
(en)
CH
(2)
CH583710A5
(en)
CS
(2)
CS173615B2
(en)
DD
(2)
DD110760A5
(en)
DE
(1)
DE2164690C3
(en)
DK
(1)
DK130293B
(en)
EG
(1)
EG11122A
(en)
ES
(1)
ES409860A1
(en)
FI
(1)
FI54299C
(en)
FR
(1)
FR2166048B1
(en)
GB
(1)
GB1360180A
(en)
HU
(1)
HU165060B
(en)
IL
(1)
IL41170A
(en)
IT
(1)
IT1043888B
(en)
KE
(1)
KE2613A
(en)
MY
(1)
MY7600092A
(en)
NL
(1)
NL153187B
(en)
NO
(1)
NO137092C
(en)
PL
(1)
PL85192B1
(en)
RO
(1)
RO71503A
(en)
SE
(1)
SE395890B
(en)
SU
(2)
SU492086A3
(en)
ZA
(1)
ZA729076B
(en)
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4299837A
(en)
1979-12-05
1981-11-10
Montedison S.P.A.
Anthelmintic benzimidazole-carbamates
Families Citing this family (29)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3965113A
(en)
*
1972-12-29
1976-06-22
Syntex (U.S.A.) Inc.
5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
HU169503B
(en)
*
1974-02-05
1976-12-28
RO64921A
(en)
*
1974-05-28
1979-07-15
Syntex Inc
PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE-2-CARBAMATE DERIVATIVES
DE2432631A1
(en)
*
1974-07-06
1976-01-22
Hoechst Ag
Alkyl 5-phenylsulphinyl-2-benzimidazolecarbamate derivs – prepd. by oxidising corresponding 5-phenylthio cpds.
DE2441201C2
(en)
*
1974-08-28
1986-08-07
Hoechst Ag, 6230 Frankfurt
2-Carbalkoxyamino-5 (6) -phenyl-sulfonyloxy-benzimidazoles and process for their preparation
DE2441202C2
(en)
*
1974-08-28
1986-05-28
Hoechst Ag, 6230 Frankfurt
2-Carbalkoxyamino-benzimidazolyl-5 (6) -sulfonic acid-phenyl ester, process for their preparation and anthelmintic compositions containing them
US4076825A
(en)
*
1977-06-22
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles
US4076828A
(en)
*
1977-02-17
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles
US4076827A
(en)
*
1977-04-28
1978-02-28
E. R. Squibb & Sons, Inc.
Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles
IT1076022B
(en)
*
1977-04-20
1985-04-22
Montedison Spa
ANTIELMINTIC BENZIMIDAZOLCARBAMMATES
SE443977B
(en)
*
1977-05-10
1986-03-17
Chinoin Gyogyszer Es Vegyeszet
PROCEDURE FOR PREPARING 5 (6) -TIO-BENZIMIDAZOLDE DERIVATIVES
US4156006A
(en)
*
1978-01-09
1979-05-22
E. R. Squibb & Sons, Inc.
Vinyl sulfide derivatives of benzimidazoles
US4136174A
(en)
*
1978-01-18
1979-01-23
E. R. Squibb & Sons, Inc.
Benzimidazolecarbamates and method
US4154846A
(en)
*
1978-06-16
1979-05-15
E. R. Squibb & Sons, Inc.
Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates
EP0028455A1
(en)
*
1979-10-12
1981-05-13
Imperial Chemical Industries Plc
5-Phenylselenobenzimidazole derivatives, their preparation and anthelmintic or fasciolicidal compositions containing them
US4662935A
(en)
*
1980-01-14
1987-05-05
Rohm And Haas Company
Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers
DE3260986D1
(en)
*
1981-03-18
1984-11-22
Ciba Geigy Ag
Anthelmintics
IE56125B1
(en)
*
1982-10-28
1991-04-24
Ici Plc
Indole derivatives
WO1990010630A1
(en)
*
1989-03-15
1990-09-20
Janssen Pharmaceutica N.V.
[5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates
NZ232785A
(en)
*
1989-03-15
1991-03-26
Janssen Pharmaceutica Nv
5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
US5538989A
(en)
1993-11-10
1996-07-23
Hoechst-Roussel Agri-Vet Company
Fenbendazole formulations
US5861142A
(en)
*
1996-03-25
1999-01-19
Schick; Mary Pichler
Method for promoting hair, nail, and skin keratinization
GB9900752D0
(en)
1999-01-15
1999-03-03
Angiogene Pharm Ltd
Benzimidazole vascular damaging agents
US7396819B2
(en)
2003-08-08
2008-07-08
Virbac Corporation
Anthelmintic formulations
US7582612B2
(en)
*
2004-03-12
2009-09-01
Hartz Mountain Corporation
Multi-action anthelmintic formulations
JP5227795B2
(en)
*
2005-07-28
2013-07-03
インターベツト・インターナシヨナル・ベー・ベー
Novel benzimidazole (thio) carbamate with antiparasitic activity and its synthesis
EP2032046B1
(en)
*
2006-06-12
2015-11-04
Smith & Nephew, Inc.
Systems and devices for tibial resection
WO2007144362A1
(en)
2006-06-14
2007-12-21
Intervet International B.V.
A suspension comprising benzimidazole carbamate and a polysorbate
CA3043549A1
(en)
2015-11-30
2017-06-08
Children’s Medical Center Corporation
Compounds for treating proliferative diseases
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3480642A
(en)
*
1967-03-22
1969-11-25
Smithkline Corp
Process for producing 2-carbalkoxyaminobenzimidazoles
DK131821C
(en)
*
1967-03-22
1976-03-08
Smith Kline French Lab
ANALOGICAL PROCEDURE FOR THE PREPARATION OF A 2-CARBALCOXYAMINOBENZIMIDAZOLE
FR2063815A5
(en)
*
1969-10-31
1971-07-09
Aries Robert
Antifungal and anthelmintic benzimidazole carbamates
0
BE
BE793358D
patent/BE793358A/en
not_active
IP Right Cessation
1971
1971-12-27
DE
DE2164690A
patent/DE2164690C3/en
not_active
Expired
1972
1972-12-19
RO
RO7273205A
patent/RO71503A/en
unknown
1972-12-20
CS
CS8805A
patent/CS173615B2/cs
unknown
1972-12-20
CH
CH827476A
patent/CH583710A5/xx
not_active
IP Right Cessation
1972-12-20
CS
CS5893A
patent/CS173650B2/cs
unknown
1972-12-20
CH
CH1856672A
patent/CH580080A5/xx
not_active
IP Right Cessation
1972-12-20
HU
HUHO1535A
patent/HU165060B/hu
unknown
1972-12-20
ES
ES409860A
patent/ES409860A1/en
not_active
Expired
1972-12-21
DD
DD178527*A
patent/DD110760A5/xx
unknown
1972-12-21
DD
DD167796A
patent/DD109219A5/xx
unknown
1972-12-21
FI
FI3637/72A
patent/FI54299C/en
active
1972-12-22
DK
DK642872AA
patent/DK130293B/en
unknown
1972-12-22
NL
NL727217532A
patent/NL153187B/en
not_active
IP Right Cessation
1972-12-22
IT
IT33528/72A
patent/IT1043888B/en
active
Protection Beyond IP Right Term
1972-12-22
AU
AU50486/72A
patent/AU465226B2/en
not_active
Expired
1972-12-22
CA
CA159,777A
patent/CA1017750A/en
not_active
Expired
1972-12-22
NO
NO4753/72A
patent/NO137092C/en
unknown
1972-12-22
AT
AT1099672A
patent/AT320638B/en
not_active
IP Right Cessation
1972-12-23
BG
BG22217A
patent/BG22080A3/xx
unknown
1972-12-23
BG
BG25960A
patent/BG20591A3/xx
unknown
1972-12-23
PL
PL1972159809A
patent/PL85192B1/pl
unknown
1972-12-25
IL
IL41170A
patent/IL41170A/en
unknown
1972-12-26
US
US05/318,271
patent/US3954791A/en
not_active
Expired – Lifetime
1972-12-26
KR
KR7201961A
patent/KR780000116B1/en
active
1972-12-26
EG
EG541/72A
patent/EG11122A/en
active
1972-12-27
ZA
ZA729076A
patent/ZA729076B/en
unknown
1972-12-27
SU
SU1865601A
patent/SU492086A3/en
active
1972-12-27
FR
FR7246316A
patent/FR2166048B1/fr
not_active
Expired
1972-12-27
SE
SE7216998A
patent/SE395890B/en
unknown
1972-12-27
GB
GB5966672A
patent/GB1360180A/en
not_active
Expired
1972-12-27
JP
JP734324A
patent/JPS5033067B2/ja
not_active
Expired
1973
1973-11-11
SU
SU1967977A
patent/SU493967A3/en
active
1976
1976-03-22
KE
KE2613*UA
patent/KE2613A/en
unknown
1976-12-30
MY
MY92/76A
patent/MY7600092A/en
unknown
Cited By (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4299837A
(en)
1979-12-05
1981-11-10
Montedison S.P.A.
Anthelmintic benzimidazole-carbamates
Also Published As
Publication number
Publication date
AT320638B
(en)
1975-02-25
ES409860A1
(en)
1975-11-16
DD109219A5
(en)
1974-10-20
ZA729076B
(en)
1973-11-28
DK130293B
(en)
1975-02-03
JPS5033067B2
(en)
1975-10-27
RO71503A
(en)
1981-01-30
SU492086A3
(en)
1975-11-15
SU493967A3
(en)
1975-11-28
FR2166048B1
(en)
1976-07-02
DE2164690C3
(en)
1981-04-16
NL153187B
(en)
1977-05-16
CH580080A5
(en)
1976-09-30
BE793358A
(en)
1973-06-27
CS173650B2
(en)
1977-02-28
KE2613A
(en)
1976-04-15
US3954791A
(en)
1976-05-04
KR780000116B1
(en)
1978-04-15
NL7217532A
(en)
1973-06-29
BG22080A3
(en)
1976-11-25
CS173615B2
(en)
1977-02-28
MY7600092A
(en)
1976-12-31
IL41170A
(en)
1977-01-31
DE2164690A1
(en)
1973-07-12
EG11122A
(en)
1977-05-31
IL41170A0
(en)
1973-02-28
HU165060B
(en)
1974-06-28
FI54299B
(en)
1978-07-31
DE2164690B2
(en)
1980-08-14
SE395890B
(en)
1977-08-29
DD110760A5
(en)
1975-01-12
JPS4880558A
(en)
1973-10-29
FR2166048A1
(en)
1973-08-10
BG20591A3
(en)
1975-12-05
DK130293C
(en)
1975-06-30
IT1043888B
(en)
1980-02-29
AU5048672A
(en)
1974-06-27
NO137092B
(en)
1977-09-19
PL85192B1
(en)
1976-04-30
FI54299C
(en)
1978-11-10
AU465226B2
(en)
1975-09-18
CH583710A5
(en)
1977-01-14
NO137092C
(en)
1977-12-28
CA1017750A
(en)
1977-09-20
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Legal Events
Date
Code
Title
Description
1974-11-27
PS
Patent sealed [section 19, patents act 1949]
1989-02-08
746B
Proceeding under section 46(3) patents act 1977
1991-06-19
746D
Case decided by the comptroller (sect. 46(3)/1977)
1993-01-27
PE20
Patent expired after termination of 20 years
Effective date:
19921225
