GB1360658A

GB1360658A – Substituted 2-hydroxy-2-phenylethyl-amines having vascular activi ty and process for their preparation
– Google Patents

GB1360658A – Substituted 2-hydroxy-2-phenylethyl-amines having vascular activi ty and process for their preparation
– Google Patents
Substituted 2-hydroxy-2-phenylethyl-amines having vascular activi ty and process for their preparation

Info

Publication number
GB1360658A

GB1360658A
GB4815271A
GB4815271A
GB1360658A
GB 1360658 A
GB1360658 A
GB 1360658A
GB 4815271 A
GB4815271 A
GB 4815271A
GB 4815271 A
GB4815271 A
GB 4815271A
GB 1360658 A
GB1360658 A
GB 1360658A
Authority
GB
United Kingdom
Prior art keywords
preparation
vascular
activi
phenylethyl
amines
Prior art date
1971-04-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB4815271A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dr L Zambeletti SpA

Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-04-22
Filing date
1971-10-15
Publication date
1974-07-17

1971-10-15
Application filed by Dr L Zambeletti SpA
filed
Critical
Dr L Zambeletti SpA

1974-07-17
Publication of GB1360658A
publication
Critical
patent/GB1360658A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings

C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members

C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms

C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings

C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms

C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Abstract

1360658 Phenylethanolamines DR L ZAMBELETTI SpA 15 Oct 1971 [22 April 1971] 48152/71 Heading C2C Compounds of the general Formula (I) (K=H, OH, OMe; R1=H, OH, Ph; R2=H, Me; R3=(CH 2 ) 2 OH, Et, Pr, Bu, Bu1, furfuryl, tetrahydrofurfuryl) and their acid addition salts are prepared by reducing a compound of the Formula (II) (X = anion). The preparation of the starting materials and 3,5 – diacetoxydiazoacetophenone, # – chloro-3,5 – dihydroxyacetophenone and # – bromo – 4- phenylacetophenone is described. The compounds of Formula (I) and their salts possess vascular activity, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.

GB4815271A
1971-04-22
1971-10-15
Substituted 2-hydroxy-2-phenylethyl-amines having vascular activi ty and process for their preparation

Expired

GB1360658A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

IT2352771A

IT1044214B
(en)

1971-04-22
1971-04-22

2 HYDROXY 2 PHENYLETHYLAMINS SO ESTABLISHED EQUIPPED WITH VASOACTIVE PROPERTIES AND PROCESS FOR THEIR PREPARATION

Publications (1)

Publication Number
Publication Date

GB1360658A
true

GB1360658A
(en)

1974-07-17

Family
ID=11207862
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB4815271A
Expired

GB1360658A
(en)

1971-04-22
1971-10-15
Substituted 2-hydroxy-2-phenylethyl-amines having vascular activi ty and process for their preparation

Country Status (2)

Country
Link

GB
(1)

GB1360658A
(en)

IT
(1)

IT1044214B
(en)

Cited By (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

EP0103830A2
(en)

*

1982-09-22
1984-03-28
Bayer Ag
Phenylethylemine derivatires as growth stimulators

WO2008022038A1
(en)

*

2006-08-10
2008-02-21
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services
Preparation of (r,r)-fenoterol and (r,r)- or (r,s)-fenoterol analogues and their use in treating congestive heart failure

US9492405B2
(en)

2010-03-10
2016-11-15
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

1971

1971-04-22
IT
IT2352771A
patent/IT1044214B/en
active

1971-10-15
GB
GB4815271A
patent/GB1360658A/en
not_active
Expired

Cited By (13)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

EP0103830A2
(en)

*

1982-09-22
1984-03-28
Bayer Ag
Phenylethylemine derivatires as growth stimulators

EP0103830A3
(en)

*

1982-09-22
1985-07-31
Bayer Ag
Phenylethylemine derivatires as growth stimulators

US9522871B2
(en)

2006-08-10
2016-12-20
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Preparation of (R,R)-fenoterol and (R,R)-or (R,S)-fenoterol analogues and their use in treating congestive heart failure

JP2010500381A
(en)

*

2006-08-10
2010-01-07
アメリカ合衆国

Preparation of (R, R) -fenoterol and (R, R)-or (R, S) -fenoterol analogs and their use in the treatment of congestive heart failure

US8703826B2
(en)

2006-08-10
2014-04-22
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health
Preparation of (R,R)-fenoterol and (R,R)-or (R,S)-fenoterol analogues and their use in treating congestive heart failure

WO2008022038A1
(en)

*

2006-08-10
2008-02-21
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services
Preparation of (r,r)-fenoterol and (r,r)- or (r,s)-fenoterol analogues and their use in treating congestive heart failure

US9908841B2
(en)

2006-08-10
2018-03-06
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure

US10308591B2
(en)

2006-08-10
2019-06-04
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure

US10562843B2
(en)

2006-08-10
2020-02-18
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Preparation of (R,R)-fenoterol and (R,R)- or (R,S)-fenoterol analogues and their use in treating congestive heart failure

US9492405B2
(en)

2010-03-10
2016-11-15
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

US10130594B2
(en)

2010-03-10
2018-11-20
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

US10617654B2
(en)

2010-03-10
2020-04-14
The Usa, As Represented By The Secretary, Department Of Health And Human Services
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

US10925840B2
(en)

2010-03-10
2021-02-23
The Usa, As Represented By The Secretary, Department Of Health And Human Services
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas

Also Published As

Publication number
Publication date

IT1044214B
(en)

1980-03-20

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Esters

Legal Events

Date
Code
Title
Description

1974-11-27
PS
Patent sealed

1981-06-03
PCNP
Patent ceased through non-payment of renewal fee

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