GB1361199A - Creación de Inventos y Patentes con Inteligencia Artificial

GB1361199A – Mercaptoalcohols and process for their manufacture
– Google Patents

GB1361199A – Mercaptoalcohols and process for their manufacture
– Google Patents
Mercaptoalcohols and process for their manufacture

Info

Publication number
GB1361199A

GB1361199A
GB4996471A
GB4996471A
GB1361199A
GB 1361199 A
GB1361199 A
GB 1361199A
GB 4996471 A
GB4996471 A
GB 4996471A
GB 4996471 A
GB4996471 A
GB 4996471A
GB 1361199 A
GB1361199 A
GB 1361199A
Authority
GB
United Kingdom
Prior art keywords
dimethyl
compounds
penam
penicillin
oct
Prior art date
1970-10-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB4996471A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-10-27
Filing date
1971-10-27
Publication date
1974-07-24

1970-10-27
Priority claimed from CH1584570A
external-priority
patent/CH542841A/en

1971-10-27
Application filed by Ciba Geigy AG
filed
Critical
Ciba Geigy AG

1974-07-24
Publication of GB1361199A
publication
Critical
patent/GB1361199A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings

C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4

C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM

C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System

C07F9/02—Phosphorus compounds

C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom

C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom

C07F9/568—Four-membered rings

Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE

Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS

Y02P20/00—Technologies relating to chemical industry

Y02P20/50—Improvements relating to the production of bulk chemicals

Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

1361199 Azetidinone derivatives CIBA-GEIGY AG 27 Oct 1971 [27 Oct 1970 10 Nov 1970 4 March 1971 25 May 1971] 49964/71 Headings C2A C2C and C2P Novel compounds (I) (including salts and isomers thereof) where Ra 1 is H or a protecting group, Rb 1 is H or acyl or Ra 1 and Rb 1 taken together signify a bivalent protecting group, R 2 is H or acyl and R 3 and R 4 are H or an organic radical bonded via a carbon atom are made by reacting compounds (II) with compounds (III) while simultaneously effecting treatment with a reducing agent (RA 1 is a protecting group). Compounds VIII, IX, XI, XII, XIII, XIV and XIVa are also prepared (XIVa is not isolated) as well as 3-isopropyl-4-thia-2,6-diazabicyclo[3,2,0]heptane- 7 – one and 4,4 – dimethyl- 5 – thia – 2,7-diazabicyclo[4,2,0]oct- 2 – en (and 2 – an – ) – 8-ones. (RA 5 and R 5 are organic radicals, Z is, e.g. halogen, R a , Rb and R c are, e.g. Ph and X 1 , in particular, is such that O-CO-X 1 is a carbonic acid ester group). The following synthesis is described and exemplified: penicillin-G # penicillin-G triethylammonium salt # penicillin-G azide # 2,2-dimethyl-6#-phenylacetylamino – 3 – (2,2,2 – trichloroethoxy – carbonyl-amino)-penam (XV) (optionally via 3 -isocyanato – 2,2 – dimethyl – 6# – phenyl – acetylamino – penam); (XV) # 6# – amino – 2,2 – dimethyl – 3 – (2,2,2 – trichloroethoxycarbonylamino)-penam. Pharmaceutical preparations especially active against micro-organisms contain (XIV) as active ingredient.

GB4996471A
1970-10-27
1971-10-27
Mercaptoalcohols and process for their manufacture

Expired

GB1361199A
(en)

Applications Claiming Priority (4)

Application Number
Priority Date
Filing Date
Title

CH1584570A

CH542841A
(en)

1970-10-27
1970-10-27
3-amino-4-(2-hydroxyethylthio)-2-oxo-azetidine derivs-pref contng ant – n-acyl derivs -intermediates for cpds with antibacterial activity

CH1663370

1970-11-10

CH319771

1971-03-04

CH760871

1971-05-25

Publications (1)

Publication Number
Publication Date

GB1361199A
true

GB1361199A
(en)

1974-07-24

Family
ID=27428585
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB4996471A
Expired

GB1361199A
(en)

1970-10-27
1971-10-27
Mercaptoalcohols and process for their manufacture

Country Status (5)

Country
Link

BE
(1)

BE774481A
(en)

DE
(1)

DE2151560A1
(en)

FR
(1)

FR2113239A5
(en)

GB
(1)

GB1361199A
(en)

NL
(1)

NL7114737A
(en)

1971

1971-10-16
DE
DE19712151560
patent/DE2151560A1/en
active
Pending

1971-10-26
NL
NL7114737A
patent/NL7114737A/xx
unknown

1971-10-26
FR
FR7138372A
patent/FR2113239A5/fr
not_active
Expired

1971-10-26
BE
BE774481A
patent/BE774481A/en
unknown

1971-10-27
GB
GB4996471A
patent/GB1361199A/en
not_active
Expired

Also Published As

Publication number
Publication date

NL7114737A
(en)

1972-05-02

FR2113239A5
(en)

1972-06-23

BE774481A
(en)

1972-04-26

DE2151560A1
(en)

1972-05-04

Información de contacto