GB1371650A – Analgesic derivatives of the series of sulphur-containing arylamines
– Google Patents
GB1371650A – Analgesic derivatives of the series of sulphur-containing arylamines
– Google Patents
Analgesic derivatives of the series of sulphur-containing arylamines
Info
Publication number
GB1371650A
GB1371650A
GB4424171A
GB4424171A
GB1371650A
GB 1371650 A
GB1371650 A
GB 1371650A
GB 4424171 A
GB4424171 A
GB 4424171A
GB 4424171 A
GB4424171 A
GB 4424171A
GB 1371650 A
GB1371650 A
GB 1371650A
Authority
GB
United Kingdom
Prior art keywords
aryl
group
sulphur
compounds
sept
Prior art date
1971-09-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4424171A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1971-09-22
Filing date
1971-09-22
Publication date
1974-10-23
Priority to BE788805D
priority
Critical
patent/BE788805A/en
1971-09-22
Application filed by Individual
filed
Critical
Individual
1971-09-22
Priority to GB4424171A
priority
patent/GB1371650A/en
1972-09-18
Priority to FR7233005A
priority
patent/FR2154528B1/fr
1972-09-20
Priority to IL40393A
priority
patent/IL40393A0/en
1972-09-20
Priority to CA152,193A
priority
patent/CA996129A/en
1972-09-21
Priority to DE2246429A
priority
patent/DE2246429C3/en
1972-09-21
Priority to CH111274A
priority
patent/CH565757A5/xx
1972-09-21
Priority to CH1382272A
priority
patent/CH566308A5/xx
1972-09-22
Priority to NL7212829A
priority
patent/NL7212829A/xx
1972-09-22
Priority to JP47094643A
priority
patent/JPS5755718B2/ja
1972-09-22
Priority to AU46984/72A
priority
patent/AU472048B2/en
1972-09-22
Priority to AR244227A
priority
patent/AR202378A1/en
1972-09-22
Priority to ES406929A
priority
patent/ES406929A1/en
1972-09-22
Priority to IN1482/72A
priority
patent/IN137842B/en
1973-05-31
Priority to AR248332A
priority
patent/AR198415A1/en
1974-10-23
Publication of GB1371650A
publication
Critical
patent/GB1371650A/en
1975-04-07
Priority to ES436363A
priority
patent/ES436363A1/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P25/00—Drugs for disorders of the nervous system
A61P25/04—Centrally acting analgesics, e.g. opioids
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C317/00—Sulfones; Sulfoxides
Abstract
1371650 Aryl sulphoxides and sulphones V LAFON 21 Sept 1972 [22 Sept 1971] 44241/71 Heading C2C Novel compounds (I) (including salts thereof) of general formula ArSO x -A-NR 1 R 2 wherein x represents 1 or 2; A represents a C 2 -C 4 alkylene group; NR 1 R 2 represents a secondary or tertiary amino group or an N-heterocyclic amino group having 5 to 7 ring atoms which may include a second hetero atom which is sulphur, oxygen or nitrogen and which may carry one or more substituents selected from C 1 -C 5 alkyl, C 1 -C 5 hydroxyalkyl groups and phenyl, and when x is 1, Ar represents an aryl or halogeno-aryl group or, when x is 1 or 2, a 2-benzimidazolyl group, are made by standard methods, especially from the corresponding thioethers and compounds of formula The invention also comprises a process for making (I) where, when x is 1, Ar is aryl or haloaryl and when x is 1 or 2, Ar is 2-benzimidazolyl by reacting ArSO n A-Cl with HNR 1 R 2 (n is 0, 1 or 2) and, if necessary, oxidizing the compounds obtained. Pharmaceutical compositions having analgesic action contain (I) as active ingredient; administration may be orally or parenterally.
GB4424171A
1971-09-22
1971-09-22
Analgesic derivatives of the series of sulphur-containing arylamines
Expired
GB1371650A
(en)
Priority Applications (16)
Application Number
Priority Date
Filing Date
Title
BE788805D
BE788805A
(en)
1971-09-22
NEW ANTALGIC DERIVATIVES FROM THE SULFUR ARYLAMINE SERIES
GB4424171A
GB1371650A
(en)
1971-09-22
1971-09-22
Analgesic derivatives of the series of sulphur-containing arylamines
FR7233005A
FR2154528B1
(en)
1971-09-22
1972-09-18
IL40393A
IL40393A0
(en)
1971-09-22
1972-09-20
Sulphone and sulphoxide derivatives of arylamines,their preparation and pharmaceutical compositions containing them
CA152,193A
CA996129A
(en)
1971-09-22
1972-09-20
Analgesic derivatives of the series of sulphur-containing arylamines
CH1382272A
CH566308A5
(en)
1971-09-22
1972-09-21
CH111274A
CH565757A5
(en)
1971-09-22
1972-09-21
DE2246429A
DE2246429C3
(en)
1971-09-22
1972-09-21
2-phenylsulfinyl compounds and analgesics containing these compounds
NL7212829A
NL7212829A
(en)
1971-09-22
1972-09-22
JP47094643A
JPS5755718B2
(en)
1971-09-22
1972-09-22
AU46984/72A
AU472048B2
(en)
1971-09-22
1972-09-22
New analgesic derivatives ofthe series of sulphur-containing arylamines
AR244227A
AR202378A1
(en)
1971-09-22
1972-09-22
PROCEDURE FOR OBTAINING N- (2-FENYLSULFONIL) -ETHYLMORPHOLINE HYDROCHLORIDE
ES406929A
ES406929A1
(en)
1971-09-22
1972-09-22
Analgesic derivatives of the series of sulphur-containing arylamines
IN1482/72A
IN137842B
(en)
1971-09-22
1972-09-22
AR248332A
AR198415A1
(en)
1971-09-22
1973-05-31
PROCEDURE FOR OBTAINING AMINATED ARYLMERCAPTAN S-OXIDES COMPOUNDS
ES436363A
ES436363A1
(en)
1971-09-22
1975-04-07
Analgesic derivatives of the series of sulphur-containing arylamines
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB4424171A
GB1371650A
(en)
1971-09-22
1971-09-22
Analgesic derivatives of the series of sulphur-containing arylamines
Publications (1)
Publication Number
Publication Date
GB1371650A
true
GB1371650A
(en)
1974-10-23
Family
ID=10432415
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB4424171A
Expired
GB1371650A
(en)
1971-09-22
1971-09-22
Analgesic derivatives of the series of sulphur-containing arylamines
Country Status (13)
Country
Link
JP
(1)
JPS5755718B2
(en)
AR
(2)
AR202378A1
(en)
AU
(1)
AU472048B2
(en)
BE
(1)
BE788805A
(en)
CA
(1)
CA996129A
(en)
CH
(2)
CH566308A5
(en)
DE
(1)
DE2246429C3
(en)
ES
(2)
ES406929A1
(en)
FR
(1)
FR2154528B1
(en)
GB
(1)
GB1371650A
(en)
IL
(1)
IL40393A0
(en)
IN
(1)
IN137842B
(en)
NL
(1)
NL7212829A
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4134996A
(en)
*
1976-08-16
1979-01-16
The Dow Chemical Company
Method for inhibiting adp-induced platelet aggregation using phenylthioalkylamines
EP0174717B1
(en)
*
1984-07-06
1992-01-22
FISONS plc
Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors
Families Citing this family (7)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
FR2285859A1
(en)
*
1974-09-30
1976-04-23
Lafon Labor
PHENYLSULFINYL-AMIDINES AND DERIVATIVES
FR2432316A1
(en)
*
1978-08-02
1980-02-29
Choay Sa
NOVEL MEDICINAL PRODUCTS CONTAINING, AS ACTIVE SUBSTANCE, BENZENESULFONE-LIKE COMPOUNDS, NOVEL SUCH COMPOUNDS AND PROCESS FOR THEIR PREPARATION
JPS5739044Y2
(en)
*
1978-08-21
1982-08-27
FR2447909A1
(en)
*
1979-01-31
1980-08-29
Choay Sa
Alkyl phenyl sulphone(s) – used as antilipaemic agents, act on the central nervous system, and affect mitosis
JPS5964720U
(en)
*
1982-10-22
1984-04-28
日本軽金属株式会社
liquid container
AR243167A1
(en)
1985-08-24
1993-07-30
Hoechst Ag
Substituted toluidines, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors
JP2933739B2
(en)
*
1990-04-09
1999-08-16
明治製菓株式会社
Thiazole or imidazole derivatives and anti-ulcer agents
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
DD70880A
(en)
*
FR2100668A1
(en)
*
1971-05-19
1972-03-24
Sumitomo Chemical Co
Pharmacol-active heterocyclic cpds
JPS4946312A
(en)
*
1972-09-05
1974-05-02
0
BE
BE788805D
patent/BE788805A/en
not_active
IP Right Cessation
1971
1971-09-22
GB
GB4424171A
patent/GB1371650A/en
not_active
Expired
1972
1972-09-18
FR
FR7233005A
patent/FR2154528B1/fr
not_active
Expired
1972-09-20
IL
IL40393A
patent/IL40393A0/en
unknown
1972-09-20
CA
CA152,193A
patent/CA996129A/en
not_active
Expired
1972-09-21
CH
CH1382272A
patent/CH566308A5/xx
not_active
IP Right Cessation
1972-09-21
DE
DE2246429A
patent/DE2246429C3/en
not_active
Expired
1972-09-21
CH
CH111274A
patent/CH565757A5/xx
not_active
IP Right Cessation
1972-09-22
JP
JP47094643A
patent/JPS5755718B2/ja
not_active
Expired
1972-09-22
IN
IN1482/72A
patent/IN137842B/en
unknown
1972-09-22
ES
ES406929A
patent/ES406929A1/en
not_active
Expired
1972-09-22
NL
NL7212829A
patent/NL7212829A/xx
not_active
Application Discontinuation
1972-09-22
AU
AU46984/72A
patent/AU472048B2/en
not_active
Expired
1972-09-22
AR
AR244227A
patent/AR202378A1/en
active
1973
1973-05-31
AR
AR248332A
patent/AR198415A1/en
active
1975
1975-04-07
ES
ES436363A
patent/ES436363A1/en
not_active
Expired
Cited By (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4134996A
(en)
*
1976-08-16
1979-01-16
The Dow Chemical Company
Method for inhibiting adp-induced platelet aggregation using phenylthioalkylamines
US4141983A
(en)
*
1976-08-16
1979-02-27
The Dow Chemical Company
Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines
EP0174717B1
(en)
*
1984-07-06
1992-01-22
FISONS plc
Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors
Also Published As
Publication number
Publication date
BE788805A
(en)
1973-01-02
AU472048B2
(en)
1976-05-13
CH565757A5
(en)
1975-08-29
DE2246429B2
(en)
1981-07-02
DE2246429C3
(en)
1982-05-19
AU4698472A
(en)
1974-03-28
ES436363A1
(en)
1977-01-01
CA996129A
(en)
1976-08-31
ES406929A1
(en)
1976-02-01
DE2246429A1
(en)
1973-03-29
JPS4836147A
(en)
1973-05-28
NL7212829A
(en)
1973-03-26
FR2154528A1
(en)
1973-05-11
IL40393A0
(en)
1972-11-28
IN137842B
(en)
1975-09-27
JPS5755718B2
(en)
1982-11-25
CH566308A5
(en)
1975-09-15
FR2154528B1
(en)
1975-10-17
AR198415A1
(en)
1974-06-21
AR202378A1
(en)
1975-06-06
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Legal Events
Date
Code
Title
Description
1975-03-05
PS
Patent sealed [section 19, patents act 1949]
1977-11-23
PLE
Entries relating assignments, transmissions, licences in the register of patents
1978-02-08
435
Patent endorsed ‘licences of right’ on the date specified (sect. 35/1949)
1991-05-15
PCNP
Patent ceased through non-payment of renewal fee
