GB1374562A – Process for the production of insulin derivatives and their medicinal use
– Google Patents
GB1374562A – Process for the production of insulin derivatives and their medicinal use
– Google Patents
Process for the production of insulin derivatives and their medicinal use
Info
Publication number
GB1374562A
GB1374562A
GB972773A
GB972773A
GB1374562A
GB 1374562 A
GB1374562 A
GB 1374562A
GB 972773 A
GB972773 A
GB 972773A
GB 972773 A
GB972773 A
GB 972773A
GB 1374562 A
GB1374562 A
GB 1374562A
Authority
GB
United Kingdom
Prior art keywords
chain
insulin derivatives
production
derivatives
medicinal use
Prior art date
1972-03-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB972773A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1972-03-01
Filing date
1973-02-28
Publication date
1974-11-20
1972-03-01
Priority claimed from DE19722209836
external-priority
patent/DE2209836C3/en
1973-02-28
Application filed by Bayer AG
filed
Critical
Bayer AG
1974-11-20
Publication of GB1374562A
publication
Critical
patent/GB1374562A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07K—PEPTIDES
C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
C07K14/575—Hormones
C07K14/62—Insulins
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K38/00—Medicinal preparations containing peptides
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
Y02P20/00—Technologies relating to chemical industry
Y02P20/50—Improvements relating to the production of bulk chemicals
Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S930/00—Peptide or protein sequence
Y10S930/01—Peptide or protein sequence
Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Abstract
1374562 Insulin derivatives; preparation BAYER AG 28 Feb 1973 [1 March 1972] 9727/73 Heading C2C The bifunctionally cross-linked insulins of partial Formula I in which X is a direct bond or a 1-15C aliphatic hydrocarbon chain of which one or more carbon atoms are optionally replaced by one or more heteroatoms and either carrying no substituents or carrying hydrophilic substituents are prepared by a sequence of reactions as exemplified in the following scheme (Y is a protecting group). The S-protected A-chain and B-chain derivatives are, e.g. the S-sulphonates. The products of partial Formula I are claimed per se in Specification 1,374,385.
GB972773A
1972-03-01
1973-02-28
Process for the production of insulin derivatives and their medicinal use
Expired
GB1374562A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
DE19722209836
DE2209836C3
(en)
1972-03-01
New insulin derivatives and processes for their production and pharmaceuticals containing them
Publications (1)
Publication Number
Publication Date
GB1374562A
true
GB1374562A
(en)
1974-11-20
Family
ID=5837579
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB972773A
Expired
GB1374562A
(en)
1972-03-01
1973-02-28
Process for the production of insulin derivatives and their medicinal use
Country Status (11)
Country
Link
US
(1)
US3847893A
(en)
JP
(1)
JPS4897890A
(en)
AT
(1)
AT324589B
(en)
BE
(1)
BE795998A
(en)
CH
(1)
CH579917A5
(en)
DK
(1)
DK145854C
(en)
FR
(1)
FR2181779B1
(en)
GB
(1)
GB1374562A
(en)
IL
(1)
IL41614A
(en)
NL
(1)
NL7302899A
(en)
SE
(1)
SE420087B
(en)
Families Citing this family (9)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
NL7411563A
(en)
*
1973-09-06
1975-03-10
Hoechst Ag
PROCEDURE FOR PREPARING SYNTHETICALLY MODIFIED TRYPSINE INHIBITORS.
DE2439296A1
(en)
*
1974-08-16
1976-02-26
Hoechst Ag
PROCESS FOR THE MANUFACTURING OF INSULIN, INSULIN ANALOGS AND DERIVATIVES
JPS5939421B2
(en)
*
1975-02-15
1984-09-22
イ−ライ リリ− アンド カンパニ−
Insulin purification method
JPS5939422B2
(en)
*
1975-02-15
1984-09-22
イ−ライ リリ− アンド カンパニ−
Insulin purification method
US4430266A
(en)
1980-11-28
1984-02-07
Eli Lilly And Company
Process for producing an insulin precursor
US5336782A
(en)
*
1991-04-24
1994-08-09
Kuraray Co., Ltd.
Long chain carboxylic acid imide ester
US6001604A
(en)
*
1993-12-29
1999-12-14
Bio-Technology General Corp.
Refolding of proinsulins without addition of reducing agents
US8618049B2
(en)
2009-09-08
2013-12-31
Stephen B. H. Kent
Ester insulin
GB201321489D0
(en)
*
2013-12-05
2014-01-22
Chemical & Biopharmaceutical Lab Of Patras S A
Biologically active insulin derivatives
Family Cites Families (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
IE36225B1
(en)
*
1971-01-28
1976-09-15
Nat Res Dev
Improvements relating to insulin derivatives
1973
1973-02-16
US
US00333366A
patent/US3847893A/en
not_active
Expired – Lifetime
1973-02-26
IL
IL41614A
patent/IL41614A/en
unknown
1973-02-27
CH
CH284773A
patent/CH579917A5/xx
not_active
IP Right Cessation
1973-02-27
JP
JP48022748A
patent/JPS4897890A/ja
active
Pending
1973-02-27
BE
BE128129A
patent/BE795998A/en
not_active
IP Right Cessation
1973-02-28
SE
SE7302819A
patent/SE420087B/en
unknown
1973-02-28
DK
DK109273A
patent/DK145854C/en
not_active
IP Right Cessation
1973-02-28
GB
GB972773A
patent/GB1374562A/en
not_active
Expired
1973-03-01
FR
FR7307335A
patent/FR2181779B1/fr
not_active
Expired
1973-03-01
AT
AT184973A
patent/AT324589B/en
not_active
IP Right Cessation
1973-03-01
NL
NL7302899A
patent/NL7302899A/xx
not_active
Application Discontinuation
Also Published As
Publication number
Publication date
NL7302899A
(en)
1973-09-04
AT324589B
(en)
1975-09-10
DE2209836B2
(en)
1976-03-18
DE2209836A1
(en)
1973-09-06
IL41614A
(en)
1975-12-31
DK145854C
(en)
1983-09-05
DK145854B
(en)
1983-03-21
IL41614A0
(en)
1973-04-30
FR2181779B1
(en)
1976-12-03
US3847893A
(en)
1974-11-12
JPS4897890A
(en)
1973-12-13
CH579917A5
(en)
1976-09-30
BE795998A
(en)
1973-08-27
FR2181779A1
(en)
1973-12-07
SE420087B
(en)
1981-09-14
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Legal Events
Date
Code
Title
Description
1975-04-03
PS
Patent sealed [section 19, patents act 1949]
1981-01-21
732
Registration of transactions, instruments or events in the register (sect. 32/1977)
1989-10-25
PCNP
Patent ceased through non-payment of renewal fee
