GB1377610A

GB1377610A – 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof
– Google Patents

GB1377610A – 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof
– Google Patents
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

Info

Publication number
GB1377610A

GB1377610A
GB6043070A
GB6043070A
GB1377610A
GB 1377610 A
GB1377610 A
GB 1377610A
GB 6043070 A
GB6043070 A
GB 6043070A
GB 6043070 A
GB6043070 A
GB 6043070A
GB 1377610 A
GB1377610 A
GB 1377610A
Authority
GB
United Kingdom
Prior art keywords
spiro
piperidine
oxazolidinones
alkyl group
atom
Prior art date
1970-12-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB6043070A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratoires Jacques Logeais SA

Original Assignee
Laboratoires Jacques Logeais SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1970-12-19
Filing date
1970-12-19
Publication date
1974-12-18

1970-12-19
Application filed by Laboratoires Jacques Logeais SA
filed
Critical
Laboratoires Jacques Logeais SA

1970-12-19
Priority to GB6043070A
priority
Critical
patent/GB1377610A/en

1971-11-29
Priority to BE775984A
priority
patent/BE775984A/en

1971-12-01
Priority to CH546255D
priority
patent/CH546255A/en

1971-12-02
Priority to FR7143246A
priority
patent/FR2117894B1/fr

1971-12-16
Priority to SE1612271A
priority
patent/SE370401B/xx

1971-12-17
Priority to JP10253571A
priority
patent/JPS5538356B1/ja

1971-12-18
Priority to ES398106A
priority
patent/ES398106A1/en

1971-12-18
Priority to DE19712163000
priority
patent/DE2163000C3/en

1974-12-18
Publication of GB1377610A
publication
Critical
patent/GB1377610A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings

C07D498/10—Spiro-condensed systems

Abstract

1377610 5 – (Piperidine – 4 – spiro) – oxazolidinones LABORATOIRES JACQUES LOGEAIS 30 Nov 1971 [19 Dec 1970] 60430/70 Heading C2C Novel 5 – (piperidine – 4 – spiro) – oxazolidinones of the general formula wherein R is a hydrogen atom or an alkyl, alkenyl, alkynyl or phenyl group, R1 is a hydrogen atom or alkyl group, R2 is a hydrogen or halogen atom or an alkyl group and B is an oxygen atom or a methylene, ethylene or -O-CHR3– group, in which the oxygen atom is bonded to the aromatic nucleus and R3 is a hydrogen atom or alkyl group, and non-toxic acid addition salts thereof are prepared by condensing a 5-(piperidine-4-spiro)-oxazolidinone and a phenoxyethyl halide of the respective general formulµ wherein X is a halogen atom, followed optionally by salifying the product. Pharmaceutical compositions having adrenolytic activity comprise, as active ingredient, a 5-(piperidine-4-spiro)-oxazolidinone of the first general formula above or a non-toxic acid addition salt thereof, together with a therapeutically acceptable vehicle, arid may be administered orally or parenterally.

GB6043070A
1970-12-19
1970-12-19
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

Expired

GB1377610A
(en)

Priority Applications (8)

Application Number
Priority Date
Filing Date
Title

GB6043070A

GB1377610A
(en)

1970-12-19
1970-12-19
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

BE775984A

BE775984A
(en)

1970-12-19
1971-11-29

(PIPERIDINE-4-SPIRO) -5 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS

CH546255D

CH546255A
(en)

1970-12-19
1971-12-01

PROCESS FOR PREPARING DERIVATIVES OF (PIPERIDINE-4SPIRO) -5 OXAZOLIDINONE.

FR7143246A

FR2117894B1
(en)

1970-12-19
1971-12-02

SE1612271A

SE370401B
(en)

1970-12-19
1971-12-16

JP10253571A

JPS5538356B1
(en)

1970-12-19
1971-12-17

ES398106A

ES398106A1
(en)

1970-12-19
1971-12-18
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

DE19712163000

DE2163000C3
(en)

1970-12-19
1971-12-18

(Piperidin-4-spiro) -5-oxazolidone, process for their preparation and pharmaceutical preparations containing these compounds

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

GB6043070A

GB1377610A
(en)

1970-12-19
1970-12-19
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

Publications (1)

Publication Number
Publication Date

GB1377610A
true

GB1377610A
(en)

1974-12-18

Family
ID=10485592
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB6043070A
Expired

GB1377610A
(en)

1970-12-19
1970-12-19
5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

Country Status (8)

Country
Link

JP
(1)

JPS5538356B1
(en)

BE
(1)

BE775984A
(en)

CH
(1)

CH546255A
(en)

DE
(1)

DE2163000C3
(en)

ES
(1)

ES398106A1
(en)

FR
(1)

FR2117894B1
(en)

GB
(1)

GB1377610A
(en)

SE
(1)

SE370401B
(en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

GB1478932A
(en)

*

1975-03-06
1977-07-06
Science Union & Cie
8-(3-chromanyl)-1-oxa-3,8-diazaspiro(4,5)decan-2-ones and thiones

ES8401072A1
(en)

*

1982-11-23
1983-12-16
Faes
Compound 3-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxopurine-7-acetyl-8-(2-phenylethyl)-1-oxa-3,8-diazaspiro-(4,5)decan-2-one and a process of preparation thereof

FR2615515B1
(en)

*

1987-05-22
1989-06-30
Adir

NOVEL SPIRO 4, 5 DECANE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Family Cites Families (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

FR2035780A1
(en)

*

1969-03-25
1970-12-24
Logeais Labor Jacques

1970

1970-12-19
GB
GB6043070A
patent/GB1377610A/en
not_active
Expired

1971

1971-11-29
BE
BE775984A
patent/BE775984A/en
not_active
IP Right Cessation

1971-12-01
CH
CH546255D
patent/CH546255A/en
not_active
IP Right Cessation

1971-12-02
FR
FR7143246A
patent/FR2117894B1/fr
not_active
Expired

1971-12-16
SE
SE1612271A
patent/SE370401B/xx
unknown

1971-12-17
JP
JP10253571A
patent/JPS5538356B1/ja
active
Pending

1971-12-18
DE
DE19712163000
patent/DE2163000C3/en
not_active
Expired

1971-12-18
ES
ES398106A
patent/ES398106A1/en
not_active
Expired

Also Published As

Publication number
Publication date

DE2163000B2
(en)

1978-04-13

CH546255A
(en)

1974-02-28

BE775984A
(en)

1972-03-16

SE370401B
(en)

1974-10-14

ES398106A1
(en)

1974-07-01

FR2117894B1
(en)

1975-06-13

JPS5538356B1
(en)

1980-10-03

DE2163000C3
(en)

1978-12-14

DE2163000A1
(en)

1972-06-29

FR2117894A1
(en)

1972-07-28

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5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof

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Legal Events

Date
Code
Title
Description

1975-04-30
PS
Patent sealed

1976-07-14
435
Patent endorsed ‘licences of right’ on the date specified (sect. 35/1949)

1992-01-02
PE20
Patent expired after termination of 20 years

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