GB1448081A – Process for the preparation of carnitine hydrochloride
– Google Patents
GB1448081A – Process for the preparation of carnitine hydrochloride
– Google Patents
Process for the preparation of carnitine hydrochloride
Info
Publication number
GB1448081A
GB1448081A
GB1561275A
GB1561275A
GB1448081A
GB 1448081 A
GB1448081 A
GB 1448081A
GB 1561275 A
GB1561275 A
GB 1561275A
GB 1561275 A
GB1561275 A
GB 1561275A
GB 1448081 A
GB1448081 A
GB 1448081A
Authority
GB
United Kingdom
Prior art keywords
carnitine hydrochloride
give
preparation
anilide
trimethylammonium
Prior art date
1974-04-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1561275A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1974-04-26
Filing date
1975-04-16
Publication date
1976-09-02
1975-04-16
Application filed by Lonza AG
filed
Critical
Lonza AG
1976-09-02
Publication of GB1448081A
publication
Critical
patent/GB1448081A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
Abstract
1448081 Carnitine hydrochloride LONZA Ltd 16 April 1975 [26 April 1974] 15612/75 Heading C2C Carnitine hydrochloride is made by (1) reacting a γ-haloacetoacetic acid anilide which can be N-alkylated or N-arylated with trimethylamine to give the corresponding γ- trimethylammonium acetoacetic anilide halide, (2) hydrogenating this product to give the corresponding γ – trimethylammonium – #- hydroxybutyric acid anilide halide and (3) reacting this product with hydrochloric acid to give the desired compound.
GB1561275A
1974-04-26
1975-04-16
Process for the preparation of carnitine hydrochloride
Expired
GB1448081A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
CH573074A
CH589604A5
(en)
1974-04-26
1974-04-26
Publications (1)
Publication Number
Publication Date
GB1448081A
true
GB1448081A
(en)
1976-09-02
Family
ID=4298393
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB1561275A
Expired
GB1448081A
(en)
1974-04-26
1975-04-16
Process for the preparation of carnitine hydrochloride
Country Status (25)
Country
Link
US
(1)
US3969406A
(en)
JP
(1)
JPS50148312A
(en)
AR
(1)
AR207361A1
(en)
AT
(1)
AT342792B
(en)
BE
(1)
BE828456A
(en)
BG
(1)
BG26371A3
(en)
BR
(1)
BR7502510A
(en)
CA
(1)
CA1034143A
(en)
CH
(1)
CH589604A5
(en)
DD
(1)
DD119575A5
(en)
DE
(1)
DE2518813C2
(en)
DK
(1)
DK174575A
(en)
ES
(1)
ES436902A1
(en)
FR
(1)
FR2268787B1
(en)
GB
(1)
GB1448081A
(en)
IE
(1)
IE41115B1
(en)
IN
(1)
IN144611B
(en)
IT
(1)
IT1035450B
(en)
LU
(1)
LU72363A1
(en)
NL
(1)
NL7504852A
(en)
NO
(1)
NO751472L
(en)
RO
(1)
RO66137A
(en)
SE
(1)
SE404691B
(en)
SU
(1)
SU544366A3
(en)
ZA
(1)
ZA752563B
(en)
Families Citing this family (6)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
IE56322B1
(en)
*
1982-12-06
1991-06-19
Sigma Tau Ind Farmaceuti
Process for preparing l-carnitine and chemical intermediates employed therein
US4642290A
(en)
*
1982-12-06
1987-02-10
Sih Charles J
Process for preparing a compound for use in the production of L-carnitine
US4710468A
(en)
*
1983-10-24
1987-12-01
Sigma-Tau Industrie Pharmaceutiche Riunite S.P.A.
Process for preparing L-carnitine and chemical intermediates employed therein
IT1190358B
(en)
*
1985-05-24
1988-02-16
Sclavo Spa
PROCEDURE FOR THE PREPARATION OF L-CARNITINA
US4788322A
(en)
*
1987-07-31
1988-11-29
Merck & Co., Inc.
Process for preparing ACHPA
JPH0678277B2
(en)
*
1988-02-19
1994-10-05
高砂香料工業株式会社
Process for producing optically active alcohol and its derivative
Family Cites Families (7)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US2328021A
(en)
*
1940-07-17
1943-08-31
Emuisol Corp
Derivatives of amines
US2530627A
(en)
*
1946-09-06
1950-11-21
Merck & Co Inc
Production of n-acyl allothreonine esters
US2571755A
(en)
*
1948-12-09
1951-10-16
Merck & Co Inc
Preparation of threonine and intermediates therefor
US3038007A
(en)
*
1958-05-23
1962-06-05
Reeve Edward Wilkins
Process for the preparation of dl-threonine
US3096368A
(en)
*
1958-07-30
1963-07-02
Process for preparing hydrolysis products of gamma-dimethyl amin-beta-hydroxybutyroni
US3135788A
(en)
*
1959-09-28
1964-06-02
Nihon Zoki Seiyaku Kabushikika
Preparation of dl-carnitine hydrochloride from trimethylamine hydrochloride and epihalogenohydrin
BE661015A
(en)
*
1965-03-12
1965-09-13
1974
1974-04-26
CH
CH573074A
patent/CH589604A5/xx
not_active
IP Right Cessation
1975
1975-01-01
AR
AR258495A
patent/AR207361A1/en
active
1975-04-16
GB
GB1561275A
patent/GB1448081A/en
not_active
Expired
1975-04-21
ZA
ZA00752563A
patent/ZA752563B/en
unknown
1975-04-21
IE
IE892/75A
patent/IE41115B1/en
unknown
1975-04-23
DK
DK174575A
patent/DK174575A/en
not_active
Application Discontinuation
1975-04-24
BR
BR3188/75D
patent/BR7502510A/en
unknown
1975-04-24
SE
SE7504782A
patent/SE404691B/en
unknown
1975-04-24
BG
BG7529774A
patent/BG26371A3/xx
unknown
1975-04-24
IT
IT49276/75A
patent/IT1035450B/en
active
1975-04-24
NO
NO751472A
patent/NO751472L/no
unknown
1975-04-24
ES
ES436902A
patent/ES436902A1/en
not_active
Expired
1975-04-24
NL
NL7504852A
patent/NL7504852A/en
not_active
Application Discontinuation
1975-04-24
JP
JP50051258A
patent/JPS50148312A/ja
active
Pending
1975-04-25
SU
SU2127884A
patent/SU544366A3/en
active
1975-04-25
AT
AT320575A
patent/AT342792B/en
not_active
IP Right Cessation
1975-04-25
DD
DD185713A
patent/DD119575A5/xx
unknown
1975-04-25
BE
BE155838A
patent/BE828456A/en
unknown
1975-04-25
LU
LU72363A
patent/LU72363A1/xx
unknown
1975-04-25
RO
RO7582091A
patent/RO66137A/en
unknown
1975-04-25
FR
FR7513098A
patent/FR2268787B1/fr
not_active
Expired
1975-04-28
DE
DE2518813A
patent/DE2518813C2/en
not_active
Expired
1975-04-28
US
US05/572,316
patent/US3969406A/en
not_active
Expired – Lifetime
1975-04-28
CA
CA225,629A
patent/CA1034143A/en
not_active
Expired
1975-06-13
IN
IN1172/CAL/75A
patent/IN144611B/en
unknown
Also Published As
Publication number
Publication date
AU8042675A
(en)
1976-10-28
LU72363A1
(en)
1977-02-03
SU544366A3
(en)
1977-01-25
DE2518813C2
(en)
1983-09-15
BG26371A3
(en)
1979-03-15
DD119575A5
(en)
1976-05-05
ATA320575A
(en)
1977-08-15
RO66137A
(en)
1980-02-15
US3969406A
(en)
1976-07-13
AR207361A1
(en)
1976-09-30
SE7504782L
(en)
1975-10-27
IT1035450B
(en)
1979-10-20
ES436902A1
(en)
1977-01-01
CH589604A5
(en)
1977-07-15
DE2518813A1
(en)
1975-11-06
IE41115B1
(en)
1979-10-24
SE404691B
(en)
1978-10-23
IN144611B
(en)
1978-05-20
IE41115L
(en)
1975-10-26
NO751472L
(en)
1975-10-28
BE828456A
(en)
1975-10-27
NL7504852A
(en)
1975-10-28
CA1034143A
(en)
1978-07-04
FR2268787B1
(en)
1980-05-09
FR2268787A1
(en)
1975-11-21
JPS50148312A
(en)
1975-11-27
ZA752563B
(en)
1976-03-31
BR7502510A
(en)
1976-03-03
DK174575A
(en)
1975-10-27
AT342792B
(en)
1978-04-25
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Legal Events
Date
Code
Title
Description
1977-01-13
PS
Patent sealed [section 19, patents act 1949]
1979-12-05
PCNP
Patent ceased through non-payment of renewal fee
