GB1457491A – Analysis system
– Google Patents
GB1457491A – Analysis system
– Google Patents
Analysis system
Info
Publication number
GB1457491A
GB1457491A
GB1274375A
GB1274375A
GB1457491A
GB 1457491 A
GB1457491 A
GB 1457491A
GB 1274375 A
GB1274375 A
GB 1274375A
GB 1274375 A
GB1274375 A
GB 1274375A
GB 1457491 A
GB1457491 A
GB 1457491A
Authority
GB
United Kingdom
Prior art keywords
electrode
chamber
silver
conduit
oxygen
Prior art date
1974-06-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1274375A
Inventor
Bernard Stein
Philip Spergel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instrumentation Laboratory Co
Original Assignee
Instrumentation Laboratory Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1974-06-27
Filing date
1975-03-26
Publication date
1976-12-01
1975-03-26
Application filed by Instrumentation Laboratory Co
filed
Critical
Instrumentation Laboratory Co
1976-12-01
Publication of GB1457491A
publication
Critical
patent/GB1457491A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor
G01N35/00584—Control arrangements for automatic analysers
G01N35/00594—Quality control, including calibration or testing of components of the analyser
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 – G01N31/00
G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
G01N33/483—Physical analysis of biological material
G01N33/487—Physical analysis of biological material of liquid biological material
G01N33/49—Blood
G01N33/4925—Blood measuring blood gas content, e.g. O2, CO2, HCO3
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor
G01N2035/00346—Heating or cooling arrangements
G01N2035/00435—Refrigerated reagent storage
G—PHYSICS
G01—MEASURING; TESTING
G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 – G01N33/00; Handling materials therefor
G01N35/00584—Control arrangements for automatic analysers
G01N35/00594—Quality control, including calibration or testing of components of the analyser
G01N35/00693—Calibration
Abstract
1457491 Determination of blood gases and pH INSTRUMENTATION LABORATORY Inc 26 March 1975 [27 June 1974] 12743/75 Headings G1B and G1N [Also in Division F2] An analysis system which may be used for determination of oxygen and carbon dioxide and of the pH in blood comprises Figs. 1, 4 a thermostatting chamber 20, first and second flow-through measuring cells 24, 26 mounted in the chamber, the chambers having a common inlet port 74, a common outlet port 76, sampling mechanism 34 and a conduit 70 connecting the sampling mechanism to the inlet port of the measuring cells, positive displacement pump means 42 and conduits 202, 96, 98 connecting the outlet ports from the measuring cells to the pump means, and flush fluid supply means 64, 38, the sampling mechanism being movable between a first position (the raised position shown in Fig. 4) for taking in a sample to be analyzed and a second position in which the sampling tube is immersed in flush fluid in the flush fluid supply means 38, the pump causing flow of the sample or of the flush fluid through both the measuring cells. In the system shown, the measuring cells comprise oxygen electrode 24, carbon dioxide electrode 26 and pH electrode 22, the sample liquid flowing from sampler mechanism 36 through heater 58 (which is itself in the thermostatting chamber) and conduit 74 to a measuring cell chamber 76 which is bounded by the surfaces of the electrodes Fig. 7. The sample liquid then flows through conduit 78, through a calibrating valve-member 52 and by conduit 202 to pH electrode 88, past calibrating electrode 50 and through pump 42 to waste at 66. The results of the measurements are displayed at 158, 168, 180. Buffer solution from supplies 60, 62 are used for calibration of the pH electrode and gases from sources at 146, 148 are used to calibrate the electrodes. The electrode assembly may comprise Fig. 7 oxygen electrode 24 which has cathode wire 250 sealed in glass envelope 252 with its tip 254 exposed and covered with oxygen-permeable membrane 256, and a silver/silver chloride anode 258; carbon dioxide electrode 26 which has pH-sensitive glass membrane 260, chamber 262 housing silver/ silver chloride electrode 264, outer chamber 266 filled with electrolyte and containing silver/silver chloride reference electrode 270, disposed over the end of the assembly a spacer membrane 272 and a carbon-dioxide-permeable membrane 274, the oxygen and carbon dioxide electrodes being seated on sealing membranes 284, 256; and pH electrode 22, Fig. 9 the pH electrode being fed with sample liquid flowing through a passageway aligned with 214 from the chamber 76 shown in Fig. 7 into conduit 306 of the electrode, the electrode comprising capillary section 300 which includes pH-sensitive glass section 88, silver/silver chloride halfcell 302 disposed in electrolyte chamber 304, the capillary section having tip portion 308 carried in seal 310 in member 312 which provides a leak junction flow-path having a «jog» 314, 316 extending to part 318 adjacent polycarbonate membrane 90, the other surface of membrane 90 being exposed to electrolyte from a reservoir (94 in Fig. 4) in which is disposed a saturated calomel halfcell reference electrode 28, the sample liquid flowing to waste via 96.
GB1274375A
1974-06-27
1975-03-26
Analysis system
Expired
GB1457491A
(en)
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
US05/483,610
US3963440A
(en)
1974-06-27
1974-06-27
Analysis system
Publications (1)
Publication Number
Publication Date
GB1457491A
true
GB1457491A
(en)
1976-12-01
Family
ID=23920779
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB1274375A
Expired
GB1457491A
(en)
1974-06-27
1975-03-26
Analysis system
Country Status (12)
Country
Link
US
(1)
US3963440A
(en)
JP
(1)
JPS513693A
(en)
BE
(1)
BE826866A
(en)
BR
(1)
BR7502687A
(en)
CA
(1)
CA1046795A
(en)
DE
(1)
DE2528819A1
(en)
FR
(1)
FR2276585A1
(en)
GB
(1)
GB1457491A
(en)
IT
(1)
IT1032771B
(en)
LU
(1)
LU72317A1
(en)
MX
(1)
MX2979E
(en)
NL
(1)
NL7503060A
(en)
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB2140133A
(en)
*
1983-05-18
1984-11-21
Integrated Engineering Limited
Fluid control valve
GB2166221A
(en)
*
1984-10-03
1986-04-30
Ti Gas Spares Ltd
Improvements in or relating to disc valves and to structures incorporating such valves
Families Citing this family (37)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4086061A
(en)
*
1977-02-28
1978-04-25
Beckman Instruments, Inc.
Temperature control system for chemical reaction cell
CA1112474A
(en)
*
1978-09-18
1981-11-17
Guy Belanger
Apparatus for the detection and the measurement of hydrogen concentration in a liquid
US4298026A
(en)
*
1979-12-17
1981-11-03
Instrumentation Laboratory Inc.
Spool valve
US4361540A
(en)
*
1980-05-05
1982-11-30
Instrumentation Laboratory Inc.
Analysis system
US4361539A
(en)
*
1980-05-05
1982-11-30
Instrumentation Laboratory Inc.
Analysis system
US4304257A
(en)
*
1980-07-01
1981-12-08
Instrumentation Laboratory Inc.
Valve with flexible sheet member
DK421880A
(en)
*
1980-10-06
1982-04-07
Radiometer As
DEVICE FOR ANALYSIS OF BIOLOGICAL LIQUIDS
US4452682A
(en)
*
1980-10-24
1984-06-05
Hitachi, Ltd.
Apparatus for measuring clinical emergency check items of blood
US4338280A
(en)
*
1981-04-02
1982-07-06
Instrumentation Laboratory Inc.
Fluid sampling
US4443407A
(en)
*
1981-04-02
1984-04-17
Instrumentation Laboratory Inc.
Analysis system
US4499053A
(en)
*
1982-06-10
1985-02-12
Instrumentation Laboratory Inc.
Fluid sampling
JPS595933A
(en)
*
1982-07-02
1984-01-12
Hitachi Ltd
Flow analysis of liquid sample
US4531088A
(en)
*
1982-08-06
1985-07-23
Allied Corporation
Blood analysis
FR2545905B1
(en)
*
1983-05-13
1987-11-27
Ferracci Francois
DEVICE FOR MEASURING CHARACTERISTICS OF A LIQUID, AND TAP, IN PARTICULAR FOR SUCH A DEVICE
US5019238A
(en)
*
1984-03-28
1991-05-28
Baxter Diagnostics Inc.
Means for quantitative determination of analyte in liquids
US4627893A
(en)
*
1984-03-28
1986-12-09
Amdev, Inc.
Means and methods for quantitative determination of analyte in liquids
JPS6151556A
(en)
*
1984-08-21
1986-03-14
Hitachi Ltd
Electrolyte analysis instrument
US4624928A
(en)
*
1984-11-01
1986-11-25
Allied Corporation
Liquid handling process
US4601881A
(en)
*
1984-11-01
1986-07-22
Allied Corporation
Liquid handling system
JPH067115B2
(en)
*
1985-03-01
1994-01-26
株式会社日立製作所
Automatic analyzer
US4640821A
(en)
*
1985-07-16
1987-02-03
Fisher Scientific Company
Analysis apparatus
US4935106A
(en)
*
1985-11-15
1990-06-19
Smithkline Diagnostics, Inc.
Ion selective/enzymatic electrode medical analyzer device and method of use
AT391214B
(en)
*
1987-06-17
1990-09-10
Avl Verbrennungskraft Messtech
ANALYZER
US4844872A
(en)
*
1987-07-17
1989-07-04
Fisher Scientific Company
Fluid handling
JP2599994Y2
(en)
*
1992-07-30
1999-09-27
株式会社堀場製作所
Automatic calibration system for laboratory ion concentration meter
US5710371A
(en)
*
1995-01-25
1998-01-20
Przedsiebiorstwo Zagraniezne Htl
Container for calibrating fluids, and device and method for measuring parameters of a sample of fluid, and oxygen electrode therefor
JPH0862179A
(en)
*
1995-02-13
1996-03-08
Hitachi Ltd
Electrolyte analyzer
FR2772129B1
(en)
*
1997-12-04
2000-02-25
Didier Roux
APPARATUS AND METHODS FOR MEASUREMENT ON A FLOWING FLOW WITH SHEAR
DE10116614C5
(en)
*
2001-04-03
2008-10-16
Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG
Automatable measuring, cleaning and calibration device for pH electrodes or electrodes for the measurement of redox potentials
WO2005047889A2
(en)
*
2003-11-12
2005-05-26
Chemtronix Inc.
Heavy metals monitoring apparatus
US20080108955A1
(en)
*
2006-11-02
2008-05-08
Blickhan Bryan J
Flow Controllers
JP4852399B2
(en)
*
2006-11-22
2012-01-11
富士フイルム株式会社
Two-component merger
US20090218535A1
(en)
*
2008-02-27
2009-09-03
Andres Pasko
Flow controllers for fluid circuits
US9121047B2
(en)
2011-04-07
2015-09-01
Life Technologies Corporation
System and methods for making and processing emulsions
WO2012139125A2
(en)
2011-04-07
2012-10-11
Life Technologies Corporation
System and methods for making and processing emulsions
DE102011120067B4
(en)
*
2011-12-05
2023-11-16
Ifm Electronic Gmbh
Sensor with an adjusting element
EP3969901A1
(en)
*
2019-05-14
2022-03-23
Radiometer Medical ApS
Methods for determining blood gas or metabolic parameters
Family Cites Families (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US3556950A
(en)
*
1966-07-15
1971-01-19
Ibm
Method and apparatus for automatic electrochemical analysis
US3658478A
(en)
*
1970-04-07
1972-04-25
Instrumentation Labor Inc
Fluid analyzing apparatus
JPS5238754B2
(en)
*
1971-10-28
1977-09-30
1974
1974-06-27
US
US05/483,610
patent/US3963440A/en
not_active
Expired – Lifetime
1975
1975-03-04
MX
MX000735U
patent/MX2979E/en
unknown
1975-03-14
NL
NL7503060A
patent/NL7503060A/en
unknown
1975-03-19
BE
BE154488A
patent/BE826866A/en
unknown
1975-03-26
GB
GB1274375A
patent/GB1457491A/en
not_active
Expired
1975-04-18
LU
LU72317A
patent/LU72317A1/xx
unknown
1975-04-21
FR
FR7512377A
patent/FR2276585A1/en
active
Granted
1975-04-23
CA
CA225,228A
patent/CA1046795A/en
not_active
Expired
1975-04-28
IT
IT68382/75A
patent/IT1032771B/en
active
1975-04-30
JP
JP50051574A
patent/JPS513693A/en
active
Pending
1975-05-02
BR
BR3420/75A
patent/BR7502687A/en
unknown
1975-06-27
DE
DE19752528819
patent/DE2528819A1/en
not_active
Withdrawn
Cited By (2)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
GB2140133A
(en)
*
1983-05-18
1984-11-21
Integrated Engineering Limited
Fluid control valve
GB2166221A
(en)
*
1984-10-03
1986-04-30
Ti Gas Spares Ltd
Improvements in or relating to disc valves and to structures incorporating such valves
Also Published As
Publication number
Publication date
BR7502687A
(en)
1976-07-06
IT1032771B
(en)
1979-06-20
JPS513693A
(en)
1976-01-13
NL7503060A
(en)
1975-12-30
CA1046795A
(en)
1979-01-23
FR2276585A1
(en)
1976-01-23
BE826866A
(en)
1975-07-16
US3963440A
(en)
1976-06-15
DE2528819A1
(en)
1976-01-15
LU72317A1
(en)
1975-08-20
MX2979E
(en)
1980-01-21
FR2276585B1
(en)
1980-07-04
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Legal Events
Date
Code
Title
Description
1977-04-14
PS
Patent sealed [section 19, patents act 1949]
1984-11-28
PCNP
Patent ceased through non-payment of renewal fee
