GB1479655A – Antibiotic preparations
– Google Patents
GB1479655A – Antibiotic preparations
– Google Patents
Antibiotic preparations
Info
Publication number
GB1479655A
GB1479655A
GB1039674A
GB1039674A
GB1479655A
GB 1479655 A
GB1479655 A
GB 1479655A
GB 1039674 A
GB1039674 A
GB 1039674A
GB 1039674 A
GB1039674 A
GB 1039674A
GB 1479655 A
GB1479655 A
GB 1479655A
Authority
GB
United Kingdom
Prior art keywords
salt
particles
penicillin
poly
cephalosporin
Prior art date
1974-03-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1039674A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1974-03-08
Filing date
1974-03-08
Publication date
1977-07-13
1974-03-08
Application filed by Beecham Group PLC
filed
Critical
Beecham Group PLC
1974-03-08
Priority to GB1039674A
priority
Critical
patent/GB1479655A/en
1975-02-21
Priority to FR7505420A
priority
patent/FR2262961A1/fr
1975-03-05
Priority to DE19752509572
priority
patent/DE2509572A1/en
1975-03-06
Priority to BE154081A
priority
patent/BE826379A/en
1977-07-13
Publication of GB1479655A
publication
Critical
patent/GB1479655A/en
Status
Expired
legal-status
Critical
Current
Links
Espacenet
Global Dossier
Discuss
Classifications
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
A61K47/12—Carboxylic acids; Salts or anhydrides thereof
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/33—Heterocyclic compounds
A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
A61K31/425—Thiazoles
A61K31/429—Thiazoles condensed with heterocyclic ring systems
A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
A61K31/33—Heterocyclic compounds
A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Abstract
1479655 Antibiotic preparation BEECHAM GROUP Ltd 5 Feb 1975 [8 March 1974] 10396/74 Heading A5B A powder which may be dispersed in water to yield an orally administerable pharmaceutical composition comprises (a) particles of particle size 5 to 500Á comprising a watersoluble acid addition salt of an in vivo hydrolysable ester of a penicillin or cephalosporin which has an amino-group in the acetylaminoside chain which particles are at least 50% coated with a pharmaceutically acceptable water-insoluble coating agent and (b) a watersoluble salt of a weak organic acid, the weight ratio (a):(b) being from 5:1 to 1:5. The salt (b) may be included within the penicillin, or cephalosporin particles. The antibiotic may be ampicillin phthalidyl ester hydrochloride or ampicillin pivaloyloxymethyl ester hydrochloride. The weak acid salt may be disodium citrate or trisodium citrate. The coating agent may be ethyl cellulose, poly(dimethylaminoethylmethacrylate) or poly- (vinyl acetal diethylaminoacetate). Other ingredients specified include monmorillonite clay, preservative, flavouring and caster sugar.
GB1039674A
1974-03-08
1974-03-08
Antibiotic preparations
Expired
GB1479655A
(en)
Priority Applications (4)
Application Number
Priority Date
Filing Date
Title
GB1039674A
GB1479655A
(en)
1974-03-08
1974-03-08
Antibiotic preparations
FR7505420A
FR2262961A1
(en)
1974-03-08
1975-02-21
DE19752509572
DE2509572A1
(en)
1974-03-08
1975-03-05
DRY PRODUCT AND FINE PARTICLES
BE154081A
BE826379A
(en)
1974-03-08
1975-03-06
SOLUBILITY MODIFYING MICROCAPSULES
Applications Claiming Priority (1)
Application Number
Priority Date
Filing Date
Title
GB1039674A
GB1479655A
(en)
1974-03-08
1974-03-08
Antibiotic preparations
Publications (1)
Publication Number
Publication Date
GB1479655A
true
GB1479655A
(en)
1977-07-13
Family
ID=9967051
Family Applications (1)
Application Number
Title
Priority Date
Filing Date
GB1039674A
Expired
GB1479655A
(en)
1974-03-08
1974-03-08
Antibiotic preparations
Country Status (4)
Country
Link
BE
(1)
BE826379A
(en)
DE
(1)
DE2509572A1
(en)
FR
(1)
FR2262961A1
(en)
GB
(1)
GB1479655A
(en)
Cited By (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4321253A
(en)
1980-08-22
1982-03-23
Beatty Morgan L
Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
US4367217A
(en)
1980-01-12
1983-01-04
Boehringer Ingelheim Gmbh
Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
GB2231266A
(en)
*
1989-04-27
1990-11-14
Parenta Srl
The preparation of sterile powders of antibiotics
Families Citing this family (4)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
AU4927979A
(en)
*
1977-03-15
1980-02-07
Beecham Group Limited
Oxazyl pencillin powders
NZ189022A
(en)
*
1977-12-08
1981-11-19
Beecham Group Ltd
Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder
IL57907A0
(en)
*
1978-08-04
1979-11-30
Beecham Group Ltd
Powder containing salts of certain penicillins for preparing orally administrable syrups
DE19835823A1
(en)
*
1998-08-10
1999-10-07
Lindopharm Gmbh
Antibiotic composition useful for preparing stable aqueous suspensions
Family Cites Families (1)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
NL7112083A
(en)
*
1970-09-16
1972-03-20
1974
1974-03-08
GB
GB1039674A
patent/GB1479655A/en
not_active
Expired
1975
1975-02-21
FR
FR7505420A
patent/FR2262961A1/fr
not_active
Withdrawn
1975-03-05
DE
DE19752509572
patent/DE2509572A1/en
not_active
Withdrawn
1975-03-06
BE
BE154081A
patent/BE826379A/en
not_active
IP Right Cessation
Cited By (3)
* Cited by examiner, † Cited by third party
Publication number
Priority date
Publication date
Assignee
Title
US4367217A
(en)
1980-01-12
1983-01-04
Boehringer Ingelheim Gmbh
Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof
US4321253A
(en)
1980-08-22
1982-03-23
Beatty Morgan L
Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
GB2231266A
(en)
*
1989-04-27
1990-11-14
Parenta Srl
The preparation of sterile powders of antibiotics
Also Published As
Publication number
Publication date
DE2509572A1
(en)
1975-09-11
BE826379A
(en)
1975-09-08
FR2262961A1
(en)
1975-10-03
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Legal Events
Date
Code
Title
Description
1977-11-23
PS
Patent sealed
1985-10-02
PCNP
Patent ceased through non-payment of renewal fee
