GB1525626A

GB1525626A – Tetrazolethiomethyl cephalosporin compounds
– Google Patents

GB1525626A – Tetrazolethiomethyl cephalosporin compounds
– Google Patents
Tetrazolethiomethyl cephalosporin compounds

Info

Publication number
GB1525626A

GB1525626A
GB36079/75A
GB3607975A
GB1525626A
GB 1525626 A
GB1525626 A
GB 1525626A
GB 36079/75 A
GB36079/75 A
GB 36079/75A
GB 3607975 A
GB3607975 A
GB 3607975A
GB 1525626 A
GB1525626 A
GB 1525626A
Authority
GB
United Kingdom
Prior art keywords
tetrazolethiomethyl
cephalosporin compounds
formula
reacting
ester
Prior art date
1974-09-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Application number
GB36079/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1974-09-03
Filing date
1975-09-02
Publication date
1978-09-20

1975-09-02
Application filed by Bristol Myers Co
filed
Critical
Bristol Myers Co

1978-09-20
Publication of GB1525626A
publication
Critical
patent/GB1525626A/en

Status
Expired
legal-status
Critical
Current

Links

Espacenet

Global Dossier

Discuss

Classifications

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

C07D257/04—Five-membered rings

A—HUMAN NECESSITIES

A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE

A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P31/04—Antibacterial agents

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS

C07C265/00—Derivatives of isocyanic acid

C—CHEMISTRY; METALLURGY

C07—ORGANIC CHEMISTRY

C07D—HETEROCYCLIC COMPOUNDS

C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom

C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms

C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Valuable antibiotics are obtained by reacting a compound of the formula in which R<1> is acyl, or a salt or a readily hydrolysable ester thereof with 5-mercapto-1-tetrazoleacetic acid. The latter can be prepared by reacting sodium azide with an isocyanate of the formula ROOCCH2NCS and hydrolysing the resulting thiol ester.

GB36079/75A
1974-09-03
1975-09-02
Tetrazolethiomethyl cephalosporin compounds

Expired

GB1525626A
(en)

Applications Claiming Priority (1)

Application Number
Priority Date
Filing Date
Title

US50299174A

1974-09-03
1974-09-03

Publications (1)

Publication Number
Publication Date

GB1525626A
true

GB1525626A
(en)

1978-09-20

Family
ID=24000311
Family Applications (1)

Application Number
Title
Priority Date
Filing Date

GB36079/75A
Expired

GB1525626A
(en)

1974-09-03
1975-09-02
Tetrazolethiomethyl cephalosporin compounds

Country Status (14)

Country
Link

JP
(2)

JPS60222489A
(en)

AT
(3)

AT349140B
(en)

AU
(1)

AU503240B2
(en)

BE
(1)

BE832725A
(en)

BG
(1)

BG27753A3
(en)

CH
(1)

CH623330A5
(en)

CS
(3)

CS202056B2
(en)

CY
(1)

CY1120A
(en)

GB
(1)

GB1525626A
(en)

HK
(1)

HK45081A
(en)

KE
(1)

KE3157A
(en)

MY
(1)

MY8200111A
(en)

SU
(2)

SU691094A3
(en)

ZA
(1)

ZA755543B
(en)

Cited By (1)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4298605A
(en)

1978-06-22
1981-11-03
Chugai Seiyaku Kabushiki Kaisha
Cephalosporin derivatives

Families Citing this family (6)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4093723A
(en)

1976-05-19
1978-06-06
Smithkline Corporation
7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins

US4082912A
(en)

1976-06-30
1978-04-04
Bristol-Myers Company
Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters

US4066762A
(en)

*

1976-07-12
1978-01-03
Smithkline Corporation
Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

US4278670A
(en)

*

1976-07-12
1981-07-14
Smithkline Corporation
7-Alpha-oxyiminoacylcephalosporins

US4117125A
(en)

1977-06-24
1978-09-26
Smithkline Corporation
7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids

JPH01300075A
(en)

*

1988-05-25
1989-12-04
Tokyo Seimitsu Hatsujo Kk
Fluid pouring device

1975

1975-08-25
BE
BE159447A
patent/BE832725A/en
not_active
IP Right Cessation

1975-08-29
ZA
ZA00755543A
patent/ZA755543B/en
unknown

1975-09-01
BG
BG7736219A
patent/BG27753A3/en
active
Active

1975-09-02
GB
GB36079/75A
patent/GB1525626A/en
not_active
Expired

1975-09-02
AT
AT676475A
patent/AT349140B/en
not_active
IP Right Cessation

1975-09-02
CY
CY1120A
patent/CY1120A/en
unknown

1975-09-02
CH
CH1134575A
patent/CH623330A5/en
not_active
IP Right Cessation

1975-09-02
AU
AU84469/75A
patent/AU503240B2/en
not_active
Expired

1975-09-03
CS
CS755997A
patent/CS202056B2/en
unknown

1975-09-03
SU
SU752170664A
patent/SU691094A3/en
active

1976

1976-08-10
SU
SU762388313A
patent/SU685157A3/en
active

1977

1977-06-07
CS
CS773750A
patent/CS202057B2/en
unknown

1977-06-07
CS
CS773751A
patent/CS202058B2/en
unknown

1977-10-10
AT
AT723377A
patent/AT348520B/en
not_active
IP Right Cessation

1978

1978-04-24
AT
AT294178A
patent/AT349638B/en
not_active
IP Right Cessation

1981

1981-08-25
KE
KE3157A
patent/KE3157A/en
unknown

1981-09-03
HK
HK450/81A
patent/HK45081A/en
unknown

1982

1982-12-30
MY
MY111/82A
patent/MY8200111A/en
unknown

1985

1985-03-11
JP
JP60046699A
patent/JPS60222489A/en
active
Granted

1985-03-11
JP
JP60046700A
patent/JPS60222470A/en
active
Granted

Cited By (4)

* Cited by examiner, † Cited by third party

Publication number
Priority date
Publication date
Assignee
Title

US4298605A
(en)

1978-06-22
1981-11-03
Chugai Seiyaku Kabushiki Kaisha
Cephalosporin derivatives

US4301161A
(en)

1978-06-22
1981-11-17
Chugai Seiyaku Kabushiki Kaisha
Cephalosporin derivatives

US4328224A
(en)

1978-06-22
1982-05-04
Chugai Seiyaku Kabushiki Kaisha
Cephalosporin derivatives

US4341776A
(en)

1978-06-22
1982-07-27
Chugai Seiyaku Kabushiki Kaisha
Cephalosporin derivatives

Also Published As

Publication number
Publication date

AT348520B
(en)

1979-02-26

ATA294178A
(en)

1978-09-15

AT349140B
(en)

1979-03-26

JPS60222489A
(en)

1985-11-07

CH623330A5
(en)

1981-05-29

BG27753A3
(en)

1979-12-12

SU685157A3
(en)

1979-09-05

ATA723377A
(en)

1978-07-15

AU503240B2
(en)

1979-08-30

ZA755543B
(en)

1976-07-28

CS202058B2
(en)

1980-12-31

JPS6135200B2
(en)

1986-08-12

AT349638B
(en)

1979-04-10

CY1120A
(en)

1981-12-04

BE832725A
(en)

1976-02-25

CS202056B2
(en)

1980-12-31

JPS60222470A
(en)

1985-11-07

SU691094A3
(en)

1979-10-05

HK45081A
(en)

1981-09-11

AU8446975A
(en)

1977-03-10

ATA676475A
(en)

1978-08-15

KE3157A
(en)

1981-09-18

CS202057B2
(en)

1980-12-31

JPS6348870B2
(en)

1988-09-30

MY8200111A
(en)

1982-12-31

Similar Documents

Publication
Publication Date
Title

SE7902954L
(en)

1979-04-03

THIAZOLYLETIC ACID ASSOCIATIONS

ES442044A1
(en)

1977-06-16

Phenyl-pyrimidines

ES426003A1
(en)

1976-07-01

{60 -amino-{60 -(ureidophenyl)acetamidocephalosporins

GB1525626A
(en)

1978-09-20

Tetrazolethiomethyl cephalosporin compounds

GB1521073A
(en)

1978-08-09

Cephalosporin compounds

DE2965574D1
(en)

1983-07-07

Adamantylalkyloxy-carbonyl derivatives, their preparation and their use for the production of peptides

ES405994A1
(en)

1975-07-16

Cephalosporins

GB1547473A
(en)

1979-06-20

Cephalosporin compounds

GB1467610A
(en)

1977-03-16

7-aminocephalosporanic acid and derivatives thereof

GB1493197A
(en)

1977-11-23

Amides of clavulanic acid

GB1240817A
(en)

1971-07-28

Herbicidal agents

IE44230L
(en)

1977-03-03

1, 3-diaza-bicyclo [3,2, 0] heptane derivatives

IL47348A
(en)

1980-11-30

7(((isothioureidomethyl)phenyl)acetamido)ceph-3-em-4-carboxylic acid derivatives

GB1539053A
(en)

1979-01-24

Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins

GB1351932A
(en)

1974-05-15

Chromone-3-carboxylic acids

ES435003A1
(en)

1977-03-16

Process for N-acylation of 7 amino cephem compounds

IE36742L
(en)

1973-04-15

Isoxazolo pyrimidines

IE38745L
(en)

1974-07-16

1-alkylideneaminouracils

GB975773A
(en)

1964-11-18

Improvements in or relating to the manufacture of photographic colour images

GB1504589A
(en)

1978-03-22

Substituted cephalosporin antibiotics

GB1533866A
(en)

1978-11-29

3-alkyl-7-oxoalkyl-xanthine derivatives

IE42384L
(en)

1976-06-21

Oxothiodimethylamides

GB1502342A
(en)

1978-03-01

Cephalosporin antibiotics

GB1479610A
(en)

1977-07-13

Cephalosporin derivatives

GB1392554A
(en)

1975-04-30

Cephalosporins

Legal Events

Date
Code
Title
Description

1979-01-10
PS
Patent sealed

1979-05-16
48S
Specification amended (sect. 8/1949)

1979-07-04
SP
Amendment (slips) printed

1989-03-08
704A
Declaration that licence is not available as of right for an excepted use (par. 4a/1977)

1995-10-04
PE20
Patent expired after termination of 20 years

Effective date:
19950901

Download PDF in English

None